Project measure / variable:   Xing1   QT_M20

ID, description, units MPD:24933   QT_M20   interval QT   [ms]  at age 20mo  
Data set, strains Xing1   inbred   27 strains     sex: both     age: 87wks
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  STRAIN COMPARISON PLOT
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Xing1 - interval QT at age 20mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested27 strains27 strains
Mean of the strain means43.2   ms 43.5   ms
Median of the strain means43.4   ms 43.6   ms
SD of the strain means± 2.19 ± 2.25
Coefficient of variation (CV)0.0506 0.0517
Min–max range of strain means38.7   –   46.1   ms 37.0   –   46.9   ms
Mean sample size per strain7.2   mice 7.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 25.943 25.943 2.5396 0.112
strain 25 1199.4977 47.9799 4.6968 < 0.0001
sex:strain 25 320.5365 12.8215 1.2551 0.1892
Residuals 321 3279.1429 10.2154


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 46.1 5.19   8 1.84 0.113 41.0, 54.0 1.34
129S1/SvImJ m 44.4 2.69   8 0.951 0.0606 39.1, 47.5 0.41
A/J f 42.8 1.92   7 0.727 0.045 40.3, 45.7 -0.17
A/J m 46.3 4.8   9 1.6 0.104 39.9, 54.5 1.25
BALB/cByJ f 45.0 3.53   9 1.18 0.0785 40.4, 49.8 0.84
BALB/cByJ m 43.6 1.76   8 0.621 0.0403 40.2, 45.5 0.05
BTBR T+ Itpr3tf/J f 39.2 2.75   7 1.04 0.0701 35.9, 42.5 -1.81
BTBR T+ Itpr3tf/J m 41.0 2.93   7 1.11 0.0715 38.2, 44.7 -1.11
BUB/BnJ f 41.9 3.53   8 1.25 0.0843 35.9, 45.5 -0.58
BUB/BnJ m 37.0 0.0   1   0.0 0.0 37.0, 37.0 -2.88
C3H/HeJ f 39.6 5.01   8 1.77 0.127 34.2, 50.5 -1.63
C3H/HeJ m 39.1 2.52   8 0.891 0.0646 36.2, 42.3 -1.95
C57BL/10J f 41.6 3.05   8 1.08 0.0733 36.6, 46.8 -0.72
C57BL/10J m 43.9 4.26   8 1.51 0.0969 38.7, 51.3 0.18
C57BL/6J f 43.5 2.9   6 1.18 0.0666 39.9, 47.6 0.15
C57BL/6J m 43.7 2.2   8 0.779 0.0504 40.6, 48.1 0.1
C57BLKS/J f 44.2 2.59   8 0.917 0.0587 40.4, 47.5 0.47
C57BLKS/J m 44.6 4.0   8 1.41 0.0897 38.3, 50.6 0.5
C57BR/cdJ f 43.0 1.78   8 0.628 0.0412 40.6, 45.2 -0.07
C57BR/cdJ m 42.5 1.63   8 0.578 0.0385 39.8, 44.5 -0.44
C57L/J f 45.4 1.86   6 0.76 0.0409 43.1, 47.9 1.02
C57L/J m 43.1 2.54   9 0.848 0.059 38.6, 48.2 -0.17
CBA/J f 43.0 2.23   9 0.742 0.0518 39.7, 45.5 -0.07
CBA/J m 45.8 4.91   8 1.74 0.107 35.5, 53.0 1.03
DBA/2J f 43.4 2.16   7 0.816 0.0497 41.1, 47.8 0.11
DBA/2J m 43.0 2.92   6 1.19 0.0679 39.0, 46.4 -0.22
FVB/NJ f 44.3 2.98   7 1.13 0.0674 40.1, 49.5 0.52
FVB/NJ m 43.8 3.0   7 1.13 0.0685 39.1, 47.8 0.14
KK/HlJ f 45.8 3.25   6 1.33 0.0709 42.5, 51.3 1.21
KK/HlJ m 41.7 2.72   7 1.03 0.0651 37.5, 44.7 -0.79
LP/J f 41.8 1.78   8 0.631 0.0427 39.5, 44.4 -0.62
LP/J m 42.5 2.24   9 0.747 0.0527 38.5, 45.3 -0.44
MRL/MpJ f 45.4 2.66   3 1.53 0.0585 43.9, 48.5 1.02
MRL/MpJ m 45.8 5.46   4 2.73 0.119 39.1, 51.7 1.03
NOD.B10Sn-H2b/J f 40.3 1.83   8 0.646 0.0453 38.0, 43.5 -1.31
NOD.B10Sn-H2b/J m 41.9 3.03   8 1.07 0.0723 38.3, 47.4 -0.7
NON/ShiLtJ f 45.7 3.75   7 1.42 0.0821 40.8, 50.6 1.16
NON/ShiLtJ m 46.9 1.72   7 0.651 0.0367 43.8, 48.8 1.52
NZO/HlLtJ f 44.1 3.84   6 1.57 0.0872 39.5, 50.5 0.43
NZO/HlLtJ m 43.1 2.29   5 1.03 0.0533 40.6, 45.4 -0.17
NZW/LacJ f 43.1 2.44   8 0.861 0.0565 38.3, 46.3 -0.03
NZW/LacJ m 44.9 3.1   8 1.1 0.0691 40.3, 49.2 0.63
P/J f 45.0 5.09   8 1.8 0.113 38.5, 53.9 0.84
P/J m 46.4 4.07   6 1.66 0.0877 39.9, 51.9 1.3
PL/J f 42.6 2.05   5 0.919 0.0482 39.0, 44.0 -0.26
PL/J m 43.5 1.06   2   0.75 0.0244 42.8, 44.3 0.01
PWD/PhJ f 38.7 4.3   8 1.52 0.111 33.6, 44.7 -2.04
PWD/PhJ m 43.4 4.52   7 1.71 0.104 33.3, 46.6 -0.04
RIIIS/J f 46.1 4.75   8 1.68 0.103 41.0, 53.1 1.34
RIIIS/J m 46.6 2.11   8 0.745 0.0452 43.7, 50.3 1.39
SM/J f 43.8 2.18   8 0.772 0.0499 40.2, 47.0 0.29
SM/J m 43.8 1.66   8 0.587 0.0379 40.8, 45.1 0.14
SWR/J f 40.0 1.85   4 0.924 0.0462 37.8, 41.8 -1.45
SWR/J m 41.8 2.2   7 0.83 0.0526 39.0, 44.5 -0.75


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 46.075 1.13 48.2982 43.8518
129S1/SvImJ m 44.375 1.13 46.5982 42.1518
A/J f 42.7857 1.208 45.1624 40.4091
A/J m 46.3444 1.0654 48.4405 44.2484
BALB/cByJ f 44.9778 1.0654 47.0738 42.8818
BALB/cByJ m 43.5875 1.13 45.8107 41.3643
BTBR T+ Itpr3tf/J f 39.2286 1.208 41.6052 36.8519
BTBR T+ Itpr3tf/J m 40.9714 1.208 43.3481 38.5948
C3H/HeJ f 39.5625 1.13 41.7857 37.3393
C3H/HeJ m 39.05 1.13 41.2732 36.8268
C57BL/10J f 41.6 1.13 43.8232 39.3768
C57BL/10J m 43.95 1.13 46.1732 41.7268
C57BL/6J f 43.5333 1.3048 46.1004 40.9662
C57BL/6J m 43.6875 1.13 45.9107 41.4643
C57BLKS/J f 44.15 1.13 46.3732 41.9268
C57BLKS/J m 44.55 1.13 46.7732 42.3268
C57BR/cdJ f 43.0375 1.13 45.2607 40.8143
C57BR/cdJ m 42.5125 1.13 44.7357 40.2893
C57L/J f 45.45 1.3048 48.0171 42.8829
C57L/J m 43.0778 1.0654 45.1738 40.9818
CBA/J f 42.9889 1.0654 45.0849 40.8929
CBA/J m 45.8125 1.13 48.0357 43.5893
DBA/2J f 43.4143 1.208 45.7909 41.0376
DBA/2J m 43.0167 1.3048 45.5838 40.4496
FVB/NJ f 44.2714 1.208 46.6481 41.8948
FVB/NJ m 43.7571 1.208 46.1338 41.3805
KK/HlJ f 45.8167 1.3048 48.3838 43.2496
KK/HlJ m 41.7286 1.208 44.1052 39.3519
LP/J f 41.8 1.13 44.0232 39.5768
LP/J m 42.5333 1.0654 44.6294 40.4373
MRL/MpJ f 45.4333 1.8453 49.0637 41.8029
MRL/MpJ m 45.75 1.5981 48.894 42.606
NOD.B10Sn-H2b/J f 40.3125 1.13 42.5357 38.0893
NOD.B10Sn-H2b/J m 41.925 1.13 44.1482 39.7018
NON/ShiLtJ f 45.6857 1.208 48.0624 43.3091
NON/ShiLtJ m 46.8571 1.208 49.2338 44.4805
NZO/HlLtJ f 44.05 1.3048 46.6171 41.4829
NZO/HlLtJ m 43.06 1.4294 45.8721 40.2479
NZW/LacJ f 43.1125 1.13 45.3357 40.8893
NZW/LacJ m 44.85 1.13 47.0732 42.6268
P/J f 45.0125 1.13 47.2357 42.7893
P/J m 46.4333 1.3048 49.0004 43.8662
PL/J f 42.62 1.4294 45.4321 39.8079
PL/J m 43.55 2.26 47.9963 39.1037
PWD/PhJ f 38.6625 1.13 40.8857 36.4393
PWD/PhJ m 43.4143 1.208 45.7909 41.0376
RIIIS/J f 46.0875 1.13 48.3107 43.8643
RIIIS/J m 46.575 1.13 48.7982 44.3518
SM/J f 43.825 1.13 46.0482 41.6018
SM/J m 43.7875 1.13 46.0107 41.5643
SWR/J f 40.05 1.5981 43.194 36.906
SWR/J m 41.8 1.208 44.1767 39.4233


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 45.225 0.799 46.797 43.653
A/J both 44.5651 0.8054 46.1495 42.9806
BALB/cByJ both 44.2826 0.7765 45.8104 42.7549
BTBR T+ Itpr3tf/J both 40.1 0.8542 41.7806 38.4194
C3H/HeJ both 39.3062 0.799 40.8783 37.7342
C57BL/10J both 42.775 0.799 44.347 41.203
C57BL/6J both 43.6104 0.8631 45.3084 41.9124
C57BLKS/J both 44.35 0.799 45.922 42.778
C57BR/cdJ both 42.775 0.799 44.347 41.203
C57L/J both 44.2639 0.8423 45.9209 42.6068
CBA/J both 44.4007 0.7765 45.9284 42.873
DBA/2J both 43.2155 0.8891 44.9647 41.4663
FVB/NJ both 44.0143 0.8542 45.6948 42.3337
KK/HlJ both 43.7726 0.8891 45.5218 42.0234
LP/J both 42.1667 0.7765 43.6944 40.6389
MRL/MpJ both 45.5917 1.2206 47.993 43.1904
NOD.B10Sn-H2b/J both 41.1187 0.799 42.6908 39.5467
NON/ShiLtJ both 46.2714 0.8542 47.952 44.5909
NZO/HlLtJ both 43.555 0.9677 45.4588 41.6512
NZW/LacJ both 43.9812 0.799 45.5533 42.4092
P/J both 45.7229 0.8631 47.4209 44.0249
PL/J both 43.085 1.337 45.7155 40.4545
PWD/PhJ both 41.0384 0.8271 42.6656 39.4112
RIIIS/J both 46.3312 0.799 47.9033 44.7592
SM/J both 43.8062 0.799 45.3783 42.2342
SWR/J both 40.925 1.0016 42.8956 38.9544




  GWAS USING LINEAR MIXED MODELS