Project measure / variable:   Xing1   QRS_M12

ID, description, units MPD:24927   QRS_M12   interval QRS   [ms]  at age 12mo  
Data set, strains Xing1   inbred   28 strains     sex: both     age: 52wks
Procedure ECG
Ontology mappings

  STRAIN COMPARISON PLOT
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Xing1 - interval QRS at age 12mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested27 strains27 strains
Mean of the strain means11.3   ms 11.1   ms
Median of the strain means11.3   ms 11.0   ms
SD of the strain means± 0.715 ± 0.886
Coefficient of variation (CV)0.0634 0.0801
Min–max range of strain means9.89   –   12.6   ms 8.93   –   12.9   ms
Mean sample size per strain7.5   mice 7.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2.8507 2.8507 2.4651 0.1173
strain 25 184.0925 7.3637 6.3677 < 0.0001
sex:strain 25 55.9617 2.2385 1.9357 0.0053
Residuals 338 390.8667 1.1564


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 12.2 0.636   8 0.225 0.0521 11.5, 13.2 1.29
129S1/SvImJ m 10.6 1.09   8 0.385 0.103 9.2, 12.2 -0.52
A/J f 11.4 0.678   7 0.256 0.0596 10.3, 12.3 0.17
A/J m 10.9 0.731   7 0.276 0.0672 9.4, 11.6 -0.18
AKR/J f 11.2 1.28   4 0.641 0.115 10.0, 13.0 -0.11
AKR/J m 10.1 0.522   5 0.233 0.0515 9.5, 10.9 -1.09
BALB/cByJ f 11.7 0.924   6 0.377 0.0792 10.4, 12.6 0.59
BALB/cByJ m 11.3 1.46   8 0.515 0.128 8.1, 12.6 0.27
BTBR T+ Itpr3tf/J f 9.89 0.508   8 0.18 0.0514 9.0, 10.7 -1.94
BTBR T+ Itpr3tf/J m 9.79 0.662   8 0.234 0.0676 9.1, 11.2 -1.44
BUB/BnJ f 10.8 1.6   7 0.606 0.149 9.0, 13.2 -0.67
BUB/BnJ m 12.0 0.972   8 0.344 0.0811 10.1, 13.1 1.06
C3H/HeJ f 10.9 1.49   8 0.525 0.136 8.7, 12.6 -0.53
C3H/HeJ m 8.93 0.57   8 0.202 0.0639 8.0, 9.7 -2.41
C57BL/10J f 11.0 1.06   8 0.375 0.0965 9.3, 12.3 -0.39
C57BL/10J m 11.3 1.52   8 0.537 0.134 7.8, 12.8 0.27
C57BL/6J f 10.6 1.17   7 0.441 0.11 9.0, 12.5 -0.95
C57BL/6J m 10.7 0.481   8 0.17 0.0451 9.8, 11.2 -0.41
C57BLKS/J f 11.2 0.49   8 0.173 0.0439 10.3, 11.9 -0.11
C57BLKS/J m 11.0 1.13   8 0.399 0.102 8.4, 11.9 -0.07
C57BR/cdJ f 11.3 0.446   6 0.182 0.0393 10.6, 11.9 0.03
C57BR/cdJ m 11.6 0.349   8 0.124 0.0301 11.1, 12.1 0.61
C57L/J f 11.5 1.23   7 0.465 0.107 9.7, 13.1 0.31
C57L/J m 10.8 0.737   8 0.26 0.0682 9.9, 11.8 -0.3
CBA/J f 11.5 1.11   8 0.393 0.0963 9.4, 12.9 0.31
CBA/J m 11.4 1.54   8 0.544 0.135 8.6, 13.3 0.38
DBA/2J f 12.2 0.757   7 0.286 0.0619 10.7, 13.0 1.29
DBA/2J m 12.1 1.35   8 0.477 0.112 9.9, 13.9 1.17
FVB/NJ f 10.6 1.03   8 0.366 0.0975 9.3, 12.1 -0.95
FVB/NJ m 10.9 1.21   8 0.426 0.111 9.4, 13.0 -0.18
KK/HlJ f 10.2 0.494   8 0.175 0.0484 9.5, 10.9 -1.51
KK/HlJ m 10.8 1.48   9 0.492 0.137 7.9, 12.7 -0.3
LP/J f 10.3 1.16   7 0.437 0.112 9.1, 11.9 -1.37
LP/J m 11.4 0.484   8 0.171 0.0423 10.7, 12.0 0.38
MRL/MpJ f 11.3 1.16   7 0.44 0.103 10.2, 13.8 0.03
MRL/MpJ m 11.5 0.74   6 0.302 0.0646 10.2, 12.5 0.49
NOD.B10Sn-H2b/J f 10.5 0.485   10 0.154 0.0461 9.9, 11.1 -1.09
NOD.B10Sn-H2b/J m 10.4 0.783   8 0.277 0.0752 9.4, 11.7 -0.75
NON/ShiLtJ f 11.8 1.05   7 0.396 0.0885 10.9, 14.0 0.73
NON/ShiLtJ m 12.4 1.64   8 0.58 0.132 10.7, 15.1 1.51
NZO/HlLtJ f 12.1 0.985   9 0.328 0.0817 10.5, 13.4 1.15
NZO/HlLtJ m 12.9 1.2   5 0.538 0.093 11.0, 14.0 2.07
NZW/LacJ f 12.3 1.69   8 0.597 0.138 10.9, 15.9 1.43
NZW/LacJ m 11.6 1.88   7 0.712 0.162 8.8, 13.7 0.61
P/J m 10.9 1.3   6 0.53 0.119 9.0, 12.4 -0.18
PL/J f 12.3 0.924   8 0.327 0.075 10.9, 13.5 1.43
PL/J m 12.3 0.281   7 0.106 0.0228 11.9, 12.7 1.4
RIIIS/J f 11.3 1.93   7 0.729 0.171 8.5, 13.9 0.03
RIIIS/J m 9.9 0.91   8 0.322 0.0919 8.2, 11.1 -1.31
SJL/J f 12.6 1.48   8 0.522 0.118 10.9, 15.6 1.85
SM/J f 10.6 1.7   7 0.644 0.161 9.3, 13.8 -0.95
SM/J m 9.98 0.755   8 0.267 0.0757 8.8, 11.1 -1.22
SWR/J f 11.2 0.587   8 0.208 0.0523 10.4, 11.9 -0.11
SWR/J m 11.2 0.42   7 0.159 0.0373 10.8, 11.8 0.15


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 12.2125 0.3802 12.9604 11.4646
129S1/SvImJ m 10.6 0.3802 11.3479 9.8521
A/J f 11.3714 0.4064 12.1709 10.5719
A/J m 10.8857 0.4064 11.6852 10.0862
AKR/J f 11.175 0.5377 12.2326 10.1174
AKR/J m 10.12 0.4809 11.066 9.174
BALB/cByJ f 11.6667 0.439 12.5302 10.8031
BALB/cByJ m 11.35 0.3802 12.0979 10.6021
BTBR T+ Itpr3tf/J f 9.8875 0.3802 10.6354 9.1396
BTBR T+ Itpr3tf/J m 9.7875 0.3802 10.5354 9.0396
BUB/BnJ f 10.8 0.4064 11.5995 10.0005
BUB/BnJ m 11.9875 0.3802 12.7354 11.2396
C3H/HeJ f 10.9125 0.3802 11.6604 10.1646
C3H/HeJ m 8.925 0.3802 9.6729 8.1771
C57BL/10J f 10.9875 0.3802 11.7354 10.2396
C57BL/10J m 11.35 0.3802 12.0979 10.6021
C57BL/6J f 10.6 0.4064 11.3995 9.8005
C57BL/6J m 10.6625 0.3802 11.4104 9.9146
C57BLKS/J f 11.1625 0.3802 11.9104 10.4146
C57BLKS/J m 11.025 0.3802 11.7729 10.2771
C57BR/cdJ f 11.35 0.439 12.2135 10.4865
C57BR/cdJ m 11.625 0.3802 12.3729 10.8771
C57L/J f 11.4857 0.4064 12.2852 10.6862
C57L/J m 10.8 0.3802 11.5479 10.0521
CBA/J f 11.55 0.3802 12.2979 10.8021
CBA/J m 11.4125 0.3802 12.1604 10.6646
DBA/2J f 12.2286 0.4064 13.0281 11.4291
DBA/2J m 12.0875 0.3802 12.8354 11.3396
FVB/NJ f 10.6125 0.3802 11.3604 9.8646
FVB/NJ m 10.9 0.3802 11.6479 10.1521
KK/HlJ f 10.2125 0.3802 10.9604 9.4646
KK/HlJ m 10.7667 0.3585 11.4718 10.0616
LP/J f 10.3429 0.4064 11.1423 9.5434
LP/J m 11.4375 0.3802 12.1854 10.6896
MRL/MpJ f 11.2571 0.4064 12.0566 10.4577
MRL/MpJ m 11.45 0.439 12.3135 10.5865
NOD.B10Sn-H2b/J f 10.53 0.3401 11.1989 9.8611
NOD.B10Sn-H2b/J m 10.4125 0.3802 11.1604 9.6646
NON/ShiLtJ f 11.8429 0.4064 12.6423 11.0434
NON/ShiLtJ m 12.45 0.3802 13.1979 11.7021
NZO/HlLtJ f 12.0556 0.3585 12.7606 11.3505
NZO/HlLtJ m 12.94 0.4809 13.886 11.994
NZW/LacJ f 12.2625 0.3802 13.0104 11.5146
NZW/LacJ m 11.6286 0.4064 12.4281 10.8291
PL/J f 12.325 0.3802 13.0729 11.5771
PL/J m 12.3286 0.4064 13.1281 11.5291
RIIIS/J f 11.2714 0.4064 12.0709 10.4719
RIIIS/J m 9.9 0.3802 10.6479 9.1521
SM/J f 10.5714 0.4064 11.3709 9.7719
SM/J m 9.975 0.3802 10.7229 9.2271
SWR/J f 11.225 0.3802 11.9729 10.4771
SWR/J m 11.2429 0.4064 12.0423 10.4434


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 11.4063 0.2688 11.9351 10.8774
A/J both 11.1286 0.2874 11.6939 10.5632
AKR/J both 10.6475 0.3607 11.357 9.938
BALB/cByJ both 11.5083 0.2904 12.0795 10.9372
BTBR T+ Itpr3tf/J both 9.8375 0.2688 10.3663 9.3087
BUB/BnJ both 11.3938 0.2783 11.9411 10.8464
C3H/HeJ both 9.9188 0.2688 10.4476 9.3899
C57BL/10J both 11.1688 0.2688 11.6976 10.6399
C57BL/6J both 10.6313 0.2783 11.1786 10.0839
C57BLKS/J both 11.0938 0.2688 11.6226 10.5649
C57BR/cdJ both 11.4875 0.2904 12.0587 10.9163
C57L/J both 11.1429 0.2783 11.6902 10.5955
CBA/J both 11.4813 0.2688 12.0101 10.9524
DBA/2J both 12.158 0.2783 12.7054 11.6107
FVB/NJ both 10.7563 0.2688 11.2851 10.2274
KK/HlJ both 10.4896 0.2613 11.0035 9.9757
LP/J both 10.8902 0.2783 11.4376 10.3428
MRL/MpJ both 11.3536 0.2991 11.942 10.7652
NOD.B10Sn-H2b/J both 10.4713 0.255 10.9729 9.9696
NON/ShiLtJ both 12.1464 0.2783 12.6938 11.5991
NZO/HlLtJ both 12.4978 0.2999 13.0877 11.9079
NZW/LacJ both 11.9455 0.2783 12.4929 11.3982
PL/J both 12.3268 0.2783 12.8742 11.7794
RIIIS/J both 10.5857 0.2783 11.1331 10.0383
SM/J both 10.2732 0.2783 10.8206 9.7258
SWR/J both 11.2339 0.2783 11.7813 10.6866




  GWAS USING LINEAR MIXED MODELS