Project measure / variable:   Xing1   PR_M12

ID, description, units MPD:24922   PR_M12   interval PR   [ms]  at age 12mo  
Data set, strains Xing1   inbred   28 strains     sex: both     age: 52wks
Procedure ECG
Ontology mappings

  STRAIN COMPARISON PLOT
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Xing1 - interval PR at age 12mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested27 strains27 strains
Mean of the strain means28.5   ms 27.4   ms
Median of the strain means28.9   ms 29.0   ms
SD of the strain means± 2.83 ± 4.19
Coefficient of variation (CV)0.0994 0.153
Min–max range of strain means20.8   –   33.6   ms 17.0   –   33.2   ms
Mean sample size per strain7.5   mice 7.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 81.2571 81.2571 5.3021 0.0219
strain 25 3978.3083 159.1323 10.3835 < 0.0001
sex:strain 25 682.0306 27.2812 1.7801 0.0133
Residuals 338 5180.0223 15.3255


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 30.2 3.39   8 1.2 0.112 21.8, 31.9 0.61
129S1/SvImJ m 22.4 3.17   8 1.12 0.141 20.2, 29.1 -1.19
A/J f 28.9 3.63   7 1.37 0.125 24.4, 34.6 0.15
A/J m 31.4 2.68   7 1.01 0.0853 27.8, 34.5 0.96
AKR/J f 31.7 5.38   4 2.69 0.17 28.6, 39.7 1.14
AKR/J m 24.4 5.22   5 2.33 0.214 16.7, 29.3 -0.71
BALB/cByJ f 27.7 2.36   6 0.963 0.0851 24.9, 31.4 -0.28
BALB/cByJ m 26.3 3.44   8 1.22 0.131 18.5, 29.1 -0.26
BTBR T+ Itpr3tf/J f 29.3 3.84   8 1.36 0.131 23.7, 34.9 0.29
BTBR T+ Itpr3tf/J m 27.7 6.25   8 2.21 0.225 18.1, 33.5 0.08
BUB/BnJ f 21.3 6.45   7 2.44 0.303 12.6, 30.3 -2.54
BUB/BnJ m 17.0 3.53   8 1.25 0.207 12.2, 21.9 -2.48
C3H/HeJ f 20.8 3.69   8 1.31 0.177 16.9, 28.5 -2.71
C3H/HeJ m 17.9 2.28   8 0.807 0.127 15.3, 22.7 -2.26
C57BL/10J f 27.1 5.19   8 1.84 0.192 20.4, 34.2 -0.49
C57BL/10J m 25.2 5.64   8 2.0 0.223 13.8, 32.9 -0.52
C57BL/6J f 29.3 4.93   7 1.86 0.168 20.5, 33.6 0.29
C57BL/6J m 30.2 3.91   8 1.38 0.129 21.1, 32.6 0.68
C57BLKS/J f 28.4 4.05   8 1.43 0.143 18.8, 31.3 -0.03
C57BLKS/J m 30.6 2.51   8 0.888 0.0822 28.7, 36.5 0.77
C57BR/cdJ f 31.8 2.2   6 0.898 0.0691 27.5, 33.6 1.17
C57BR/cdJ m 29.5 2.64   8 0.934 0.0896 25.3, 32.4 0.51
C57L/J f 30.0 5.19   7 1.96 0.173 21.2, 34.0 0.54
C57L/J m 30.6 3.44   8 1.22 0.113 24.5, 33.9 0.77
CBA/J f 29.1 4.02   8 1.42 0.138 19.8, 32.0 0.22
CBA/J m 29.7 4.15   8 1.47 0.14 20.0, 32.6 0.56
DBA/2J f 29.1 5.57   7 2.1 0.191 21.4, 35.8 0.22
DBA/2J m 29.0 5.3   8 1.87 0.183 18.4, 37.3 0.39
FVB/NJ f 27.1 2.04   8 0.722 0.0753 25.2, 31.8 -0.49
FVB/NJ m 26.4 3.4   8 1.2 0.129 20.5, 30.7 -0.23
KK/HlJ f 27.8 1.11   8 0.393 0.04 25.8, 29.3 -0.24
KK/HlJ m 27.5 2.68   9 0.894 0.0974 21.5, 30.7 0.03
LP/J f 27.5 5.84   7 2.21 0.213 18.0, 33.2 -0.35
LP/J m 29.8 2.19   8 0.774 0.0736 26.4, 33.8 0.58
MRL/MpJ f 28.0 5.35   7 2.02 0.191 21.1, 35.2 -0.17
MRL/MpJ m 23.7 5.53   6 2.26 0.233 19.0, 33.1 -0.88
NOD.B10Sn-H2b/J f 30.1 1.16   10 0.366 0.0385 28.1, 32.0 0.57
NOD.B10Sn-H2b/J m 29.6 1.03   8 0.363 0.0347 27.8, 31.4 0.53
NON/ShiLtJ f 29.1 3.19   7 1.21 0.109 25.8, 34.7 0.22
NON/ShiLtJ m 30.5 3.96   8 1.4 0.13 24.2, 36.6 0.75
NZO/HlLtJ f 30.6 3.52   9 1.17 0.115 23.3, 36.1 0.75
NZO/HlLtJ m 31.9 1.77   5 0.793 0.0556 29.9, 34.7 1.08
NZW/LacJ f 33.6 1.54   8 0.544 0.0458 31.8, 36.1 1.81
NZW/LacJ m 33.2 3.0   7 1.13 0.0904 27.4, 36.4 1.39
P/J m 21.2 2.64   6 1.08 0.125 18.5, 26.2 -1.47
PL/J f 28.0 5.63   8 1.99 0.201 20.6, 35.3 -0.17
PL/J m 31.6 3.96   7 1.49 0.125 24.2, 35.9 1.01
RIIIS/J f 28.3 2.08   7 0.787 0.0736 24.9, 31.5 -0.06
RIIIS/J m 25.6 1.97   8 0.698 0.0771 23.1, 27.7 -0.42
SJL/J f 28.5 2.26   8 0.799 0.0795 24.4, 30.8 0.01
SM/J f 24.1 5.44   7 2.06 0.226 18.4, 31.4 -1.55
SM/J m 25.6 5.46   8 1.93 0.213 18.5, 31.8 -0.42
SWR/J f 31.6 1.52   8 0.537 0.0481 29.6, 34.2 1.1
SWR/J m 30.5 4.38   7 1.65 0.144 21.3, 35.2 0.75


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 30.1625 1.3841 32.885 27.44
129S1/SvImJ m 22.4375 1.3841 25.16 19.715
A/J f 28.9286 1.4796 31.8391 26.0181
A/J m 31.4143 1.4796 34.3248 28.5038
AKR/J f 31.65 1.9574 35.5002 27.7998
AKR/J m 24.36 1.7507 27.8037 20.9163
BALB/cByJ f 27.7167 1.5982 30.8603 24.573
BALB/cByJ m 26.275 1.3841 28.9975 23.5525
BTBR T+ Itpr3tf/J f 29.2875 1.3841 32.01 26.565
BTBR T+ Itpr3tf/J m 27.75 1.3841 30.4725 25.0275
BUB/BnJ f 21.3143 1.4796 24.2248 18.4038
BUB/BnJ m 17.025 1.3841 19.7475 14.3025
C3H/HeJ f 20.825 1.3841 23.5475 18.1025
C3H/HeJ m 17.95 1.3841 20.6725 15.2275
C57BL/10J f 27.0875 1.3841 29.81 24.365
C57BL/10J m 25.25 1.3841 27.9725 22.5275
C57BL/6J f 29.2857 1.4796 32.1962 26.3752
C57BL/6J m 30.2125 1.3841 32.935 27.49
C57BLKS/J f 28.375 1.3841 31.0975 25.6525
C57BLKS/J m 30.575 1.3841 33.2975 27.8525
C57BR/cdJ f 31.8167 1.5982 34.9603 28.673
C57BR/cdJ m 29.5 1.3841 32.2225 26.7775
C57L/J f 30.0429 1.4796 32.9533 27.1324
C57L/J m 30.5625 1.3841 33.285 27.84
CBA/J f 29.0625 1.3841 31.785 26.34
CBA/J m 29.7125 1.3841 32.435 26.99
DBA/2J f 29.1 1.4796 32.0105 26.1895
DBA/2J m 28.9875 1.3841 31.71 26.265
FVB/NJ f 27.125 1.3841 29.8475 24.4025
FVB/NJ m 26.35 1.3841 29.0725 23.6275
KK/HlJ f 27.8 1.3841 30.5225 25.0775
KK/HlJ m 27.5444 1.3049 30.1112 24.9776
LP/J f 27.4714 1.4796 30.3819 24.5609
LP/J m 29.75 1.3841 32.4725 27.0275
MRL/MpJ f 28.0 1.4796 30.9105 25.0895
MRL/MpJ m 23.6667 1.5982 26.8103 20.523
NOD.B10Sn-H2b/J f 30.11 1.238 32.5451 27.6749
NOD.B10Sn-H2b/J m 29.5875 1.3841 32.31 26.865
NON/ShiLtJ f 29.1286 1.4796 32.0391 26.2181
NON/ShiLtJ m 30.525 1.3841 33.2475 27.8025
NZO/HlLtJ f 30.6 1.3049 33.1668 28.0332
NZO/HlLtJ m 31.9 1.7507 35.3437 28.4563
NZW/LacJ f 33.6375 1.3841 36.36 30.915
NZW/LacJ m 33.1714 1.4796 36.0819 30.2609
PL/J f 28.0125 1.3841 30.735 25.29
PL/J m 31.6429 1.4796 34.5533 28.7324
RIIIS/J f 28.2857 1.4796 31.1962 25.3752
RIIIS/J m 25.6125 1.3841 28.335 22.89
SM/J f 24.1 1.4796 27.0105 21.1895
SM/J m 25.6125 1.3841 28.335 22.89
SWR/J f 31.5625 1.3841 34.285 28.84
SWR/J m 30.4571 1.4796 33.3676 27.5467


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 26.3 0.9787 28.2251 24.3749
A/J both 30.1714 1.0463 32.2294 28.1134
AKR/J both 28.005 1.3131 30.5878 25.4222
BALB/cByJ both 26.9958 1.0571 29.0752 24.9165
BTBR T+ Itpr3tf/J both 28.5188 0.9787 30.4439 26.5936
BUB/BnJ both 19.1696 1.013 21.1623 17.177
C3H/HeJ both 19.3875 0.9787 21.3126 17.4624
C57BL/10J both 26.1688 0.9787 28.0939 24.2436
C57BL/6J both 29.7491 1.013 31.7418 27.7564
C57BLKS/J both 29.475 0.9787 31.4001 27.5499
C57BR/cdJ both 30.6583 1.0571 32.7377 28.579
C57L/J both 30.3027 1.013 32.2953 28.31
CBA/J both 29.3875 0.9787 31.3126 27.4624
DBA/2J both 29.0438 1.013 31.0364 27.0511
FVB/NJ both 26.7375 0.9787 28.6626 24.8124
KK/HlJ both 27.6722 0.9511 29.5431 25.8014
LP/J both 28.6107 1.013 30.6034 26.618
MRL/MpJ both 25.8333 1.089 27.9754 23.6913
NOD.B10Sn-H2b/J both 29.8488 0.9285 31.6751 28.0224
NON/ShiLtJ both 29.8268 1.013 31.8195 27.8341
NZO/HlLtJ both 31.25 1.0918 33.3975 29.1025
NZW/LacJ both 33.4045 1.013 35.3971 31.4118
PL/J both 29.8277 1.013 31.8203 27.835
RIIIS/J both 26.9491 1.013 28.9418 24.9564
SM/J both 24.8563 1.013 26.8489 22.8636
SWR/J both 31.0098 1.013 33.0025 29.0172




  GWAS USING LINEAR MIXED MODELS