Project measure / variable:   Xing1   RR_M06

ID, description, units MPD:24916   RR_M06   interval RR   [ms]  at age 6mo  
Data set, strains Xing1   inbred   28 strains     sex: both     age: 26wks
Procedure ECG
Ontology mappings

  STRAIN COMPARISON PLOT
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Xing1 - interval RR at age 6mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested28 strains27 strains
Mean of the strain means82.7   ms 80.9   ms
Median of the strain means82.5   ms 79.7   ms
SD of the strain means± 3.77 ± 4.25
Coefficient of variation (CV)0.0456 0.0525
Min–max range of strain means75.0   –   92.0   ms 74.3   –   92.1   ms
Mean sample size per strain7.5   mice 7.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 332.4234 332.4234 12.1763 0.0005
strain 26 5258.9932 202.269 7.4089 < 0.0001
sex:strain 26 1021.7106 39.2966 1.4394 0.0787
Residuals 348 9500.6603 27.3007


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 84.9 5.32   8 1.88 0.0627 77.7, 93.4 0.58
129S1/SvImJ m 80.0 5.85   7 2.21 0.0731 72.9, 88.4 -0.21
A/J f 83.8 8.59   8 3.04 0.102 75.1, 95.8 0.29
A/J m 88.3 10.8   8 3.82 0.122 74.6, 108.0 1.75
AKR/J f 77.1 1.9   8 0.672 0.0247 74.6, 80.5 -1.49
AKR/J m 78.5 2.01   7 0.761 0.0256 76.3, 81.5 -0.56
BALB/cByJ f 86.3 3.03   7 1.14 0.0351 82.4, 91.0 0.95
BALB/cByJ m 89.4 2.84   8 1.0 0.0318 85.4, 93.8 2.01
BTBR T+ Itpr3tf/J f 83.2 3.4   6 1.39 0.0408 80.2, 88.1 0.13
BUB/BnJ f 76.0 2.49   7 0.94 0.0327 73.5, 79.6 -1.78
BUB/BnJ m 76.5 1.97   7 0.743 0.0257 74.2, 79.4 -1.03
C3H/HeJ f 81.6 9.06   8 3.2 0.111 73.9, 97.4 -0.29
C3H/HeJ m 74.3 2.35   7 0.89 0.0317 71.4, 77.9 -1.55
C57BL/10J f 85.0 7.69   7 2.9 0.0905 76.2, 96.0 0.61
C57BL/10J m 79.0 1.95   8 0.69 0.0247 76.2, 81.9 -0.44
C57BL/6J f 81.6 1.14   8 0.404 0.014 79.6, 83.2 -0.29
C57BL/6J m 79.7 1.69   8 0.599 0.0213 77.1, 82.0 -0.28
C57BLKS/J f 89.3 7.87   8 2.78 0.0881 83.1, 108.0 1.75
C57BLKS/J m 83.5 4.26   7 1.61 0.051 78.5, 89.4 0.62
C57BR/cdJ f 82.4 2.65   7 1.0 0.0321 80.0, 86.7 -0.08
C57BR/cdJ m 80.6 2.42   7 0.915 0.03 75.9, 82.4 -0.07
C57L/J f 81.3 2.38   8 0.84 0.0292 78.3, 85.8 -0.37
C57L/J m 81.9 3.06   8 1.08 0.0374 78.7, 87.5 0.24
CBA/J f 81.0 4.98   7 1.88 0.0615 76.0, 91.4 -0.45
CBA/J m 78.3 1.95   8 0.69 0.0249 75.4, 80.9 -0.61
DBA/2J f 84.6 1.88   8 0.666 0.0222 81.9, 87.5 0.5
DBA/2J m 82.0 4.08   8 1.44 0.0498 77.7, 90.6 0.26
FVB/NJ f 78.0 3.34   8 1.18 0.0428 73.5, 82.6 -1.25
FVB/NJ m 76.9 2.03   7 0.766 0.0264 73.8, 79.3 -0.94
KK/HlJ f 82.5 2.02   8 0.713 0.0244 80.1, 86.6 -0.05
KK/HlJ m 80.5 3.1   8 1.1 0.0385 76.1, 86.0 -0.09
LP/J f 83.0 5.87   6 2.4 0.0707 77.5, 90.5 0.08
LP/J m 77.5 5.02   8 1.77 0.0647 70.4, 84.9 -0.8
MRL/MpJ f 83.0 3.73   6 1.52 0.045 79.8, 89.5 0.08
MRL/MpJ m 79.4 2.79   8 0.985 0.0351 76.9, 85.1 -0.35
NOD.B10Sn-H2b/J f 75.0 3.11   6 1.27 0.0415 70.5, 78.9 -2.04
NOD.B10Sn-H2b/J m 76.5 2.46   4 1.23 0.0321 73.5, 79.2 -1.03
NON/ShiLtJ f 84.1 2.19   8 0.774 0.026 80.5, 87.5 0.37
NON/ShiLtJ m 85.3 3.97   8 1.4 0.0465 79.5, 91.4 1.04
NZO/HlLtJ f 81.7 5.07   8 1.79 0.0621 77.8, 93.0 -0.27
NZO/HlLtJ m 78.9 2.2   7 0.833 0.0279 75.3, 81.0 -0.47
NZW/LacJ f 88.2 9.78   8 3.46 0.111 75.4, 107.0 1.46
NZW/LacJ m 85.7 10.7   7 4.06 0.125 77.5, 107.0 1.13
P/J f 79.9 2.06   5 0.922 0.0258 78.1, 83.3 -0.74
P/J m 78.7 2.44   7 0.921 0.031 75.3, 82.6 -0.51
PL/J f 81.9 3.85   10 1.22 0.047 76.9, 87.3 -0.21
PL/J m 81.1 4.01   5 1.79 0.0495 76.9, 86.3 0.05
RIIIS/J f 92.0 15.2   8 5.39 0.166 76.7, 119.0 2.47
RIIIS/J m 92.1 8.53   7 3.22 0.0926 80.0, 106.0 2.64
SJL/J f 86.3 5.53   8 1.96 0.0641 78.6, 93.5 0.95
SJL/J m 77.2 1.65   8 0.584 0.0214 74.3, 79.2 -0.87
SM/J f 80.8 3.0   8 1.06 0.0372 77.5, 85.9 -0.51
SM/J m 78.6 1.32   8 0.468 0.0168 77.1, 80.6 -0.54
SWR/J f 81.3 4.92   8 1.74 0.0605 74.7, 89.4 -0.37
SWR/J m 83.4 5.85   8 2.07 0.0701 73.5, 93.3 0.59


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 84.85 1.8473 88.4833 81.2167
129S1/SvImJ m 80.0286 1.9749 83.9128 76.1444
A/J f 83.8125 1.8473 87.4458 80.1792
A/J m 88.3125 1.8473 91.9458 84.6792
AKR/J f 77.0875 1.8473 80.7208 73.4542
AKR/J m 78.5 1.9749 82.3842 74.6158
BALB/cByJ f 86.2571 1.9749 90.1413 82.373
BALB/cByJ m 89.375 1.8473 93.0083 85.7417
BUB/BnJ f 75.9714 1.9749 79.8556 72.0872
BUB/BnJ m 76.5143 1.9749 80.3985 72.6301
C3H/HeJ f 81.5625 1.8473 85.1958 77.9292
C3H/HeJ m 74.3286 1.9749 78.2128 70.4444
C57BL/10J f 84.9571 1.9749 88.8413 81.073
C57BL/10J m 79.0375 1.8473 82.6708 75.4042
C57BL/6J f 81.625 1.8473 85.2583 77.9917
C57BL/6J m 79.6625 1.8473 83.2958 76.0292
C57BLKS/J f 89.35 1.8473 92.9833 85.7167
C57BLKS/J m 83.5429 1.9749 87.427 79.6587
C57BR/cdJ f 82.4286 1.9749 86.3128 78.5444
C57BR/cdJ m 80.5714 1.9749 84.4556 76.6872
C57L/J f 81.35 1.8473 84.9833 77.7167
C57L/J m 81.85 1.8473 85.4833 78.2167
CBA/J f 81.0 1.9749 84.8842 77.1158
CBA/J m 78.3125 1.8473 81.9458 74.6792
DBA/2J f 84.6125 1.8473 88.2458 80.9792
DBA/2J m 82.0375 1.8473 85.6708 78.4042
FVB/NJ f 78.0125 1.8473 81.6458 74.3792
FVB/NJ m 76.8857 1.9749 80.7699 73.0015
KK/HlJ f 82.5375 1.8473 86.1708 78.9042
KK/HlJ m 80.4625 1.8473 84.0958 76.8292
LP/J f 83.0333 2.1331 87.2287 78.8379
LP/J m 77.5375 1.8473 81.1708 73.9042
MRL/MpJ f 83.0167 2.1331 87.2121 78.8213
MRL/MpJ m 79.4 1.8473 83.0333 75.7667
NOD.B10Sn-H2b/J f 75.0167 2.1331 79.2121 70.8213
NOD.B10Sn-H2b/J m 76.5 2.6125 81.6383 71.3617
NON/ShiLtJ f 84.075 1.8473 87.7083 80.4417
NON/ShiLtJ m 85.325 1.8473 88.9583 81.6917
NZO/HlLtJ f 81.7375 1.8473 85.3708 78.1042
NZO/HlLtJ m 78.9 1.9749 82.7842 75.0158
NZW/LacJ f 88.2375 1.8473 91.8708 84.6042
NZW/LacJ m 85.7 1.9749 89.5842 81.8158
P/J f 79.92 2.3367 84.5158 75.3242
P/J m 78.7286 1.9749 82.6128 74.8444
PL/J f 81.88 1.6523 85.1297 78.6303
PL/J m 81.06 2.3367 85.6558 76.4642
RIIIS/J f 92.025 1.8473 95.6583 88.3917
RIIIS/J m 92.1 1.9749 95.9842 88.2158
SJL/J f 86.3 1.8473 89.9333 82.6667
SJL/J m 77.2 1.8473 80.8333 73.5667
SM/J f 80.75 1.8473 84.3833 77.1167
SM/J m 78.6 1.8473 82.2333 74.9667
SWR/J f 81.325 1.8473 84.9583 77.6917
SWR/J m 83.4125 1.8473 87.0458 79.7792


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 82.4393 1.3521 85.0986 79.78
A/J both 86.0625 1.3063 88.6316 83.4934
AKR/J both 77.7937 1.3521 80.4531 75.1344
BALB/cByJ both 87.8161 1.3521 90.4754 85.1568
BUB/BnJ both 76.2429 1.3964 78.9894 73.4963
C3H/HeJ both 77.9455 1.3521 80.6049 75.2862
C57BL/10J both 81.9973 1.3521 84.6566 79.338
C57BL/6J both 80.6437 1.3063 83.2129 78.0746
C57BLKS/J both 86.4464 1.3521 89.1057 83.7871
C57BR/cdJ both 81.5 1.3964 84.2465 78.7535
C57L/J both 81.6 1.3063 84.1691 79.0309
CBA/J both 79.6563 1.3521 82.3156 76.9969
DBA/2J both 83.325 1.3063 85.8941 80.7559
FVB/NJ both 77.4491 1.3521 80.1084 74.7898
KK/HlJ both 81.5 1.3063 84.0691 78.9309
LP/J both 80.2854 1.4109 83.0604 77.5104
MRL/MpJ both 81.2083 1.4109 83.9833 78.4333
NOD.B10Sn-H2b/J both 75.7583 1.6864 79.0751 72.4416
NON/ShiLtJ both 84.7 1.3063 87.2691 82.1309
NZO/HlLtJ both 80.3187 1.3521 82.9781 77.6594
NZW/LacJ both 86.9687 1.3521 89.6281 84.3094
P/J both 79.3243 1.5297 82.333 76.3156
PL/J both 81.47 1.4309 84.2844 78.6556
RIIIS/J both 92.0625 1.3521 94.7218 89.4032
SJL/J both 81.75 1.3063 84.3191 79.1809
SM/J both 79.675 1.3063 82.2441 77.1059
SWR/J both 82.3688 1.3063 84.9379 79.7996




  GWAS USING LINEAR MIXED MODELS