Project measure / variable:   Xing1   HR_M06

ID, description, units MPD:24901   HR_M06   heart rate   [n/min]  at age 6mo  
Data set, strains Xing1   inbred   28 strains     sex: both     age: 26wks
Procedure ECG
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  STRAIN COMPARISON PLOT
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Xing1 - heart rate at age 6mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested28 strains27 strains
Mean of the strain means731   n/min 747   n/min
Median of the strain means728   n/min 754   n/min
SD of the strain means± 31.0 ± 35.2
Coefficient of variation (CV)0.0425 0.0472
Min–max range of strain means672   –   801   n/min 657   –   808   n/min
Mean sample size per strain7.5   mice 7.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 24690.2073 24690.2073 14.5923 0.0002
strain 26 353604.593 13600.1767 8.0379 < 0.0001
sex:strain 26 71856.7763 2763.7222 1.6334 0.0281
Residuals 348 588818.7643 1692.0079


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 710.0 44.4   8 15.7 0.0626 642.0, 773.0 -0.67
129S1/SvImJ m 753.0 53.7   7 20.3 0.0713 679.0, 823.0 0.18
A/J f 723.0 72.9   8 25.8 0.101 627.0, 799.0 -0.25
A/J m 703.0 86.1   8 30.5 0.122 555.0, 804.0 -1.24
AKR/J f 782.0 14.9   8 5.26 0.019 759.0, 805.0 1.65
AKR/J m 766.0 20.0   7 7.56 0.0261 737.0, 787.0 0.55
BALB/cByJ f 697.0 24.2   7 9.15 0.0348 660.0, 728.0 -1.09
BALB/cByJ m 673.0 20.9   8 7.39 0.0311 640.0, 702.0 -2.09
BTBR T+ Itpr3tf/J f 722.0 29.1   6 11.9 0.0403 681.0, 748.0 -0.28
BUB/BnJ f 791.0 25.3   7 9.56 0.032 754.0, 817.0 1.94
BUB/BnJ m 787.0 20.1   7 7.59 0.0255 755.0, 809.0 1.14
C3H/HeJ f 744.0 72.4   8 25.6 0.0972 625.0, 812.0 0.43
C3H/HeJ m 808.0 25.5   7 9.64 0.0316 770.0, 841.0 1.74
C57BL/10J f 711.0 62.7   7 23.7 0.0882 625.0, 787.0 -0.64
C57BL/10J m 760.0 18.3   8 6.48 0.0241 733.0, 787.0 0.38
C57BL/6J f 735.0 10.6   8 3.74 0.0144 721.0, 754.0 0.14
C57BL/6J m 754.0 15.9   8 5.63 0.0211 732.0, 778.0 0.21
C57BLKS/J f 678.0 46.8   8 16.5 0.0691 571.0, 722.0 -1.7
C57BLKS/J m 720.0 36.0   7 13.6 0.05 672.0, 764.0 -0.76
C57BR/cdJ f 729.0 22.9   7 8.65 0.0314 693.0, 750.0 -0.06
C57BR/cdJ m 746.0 22.9   7 8.65 0.0307 730.0, 791.0 -0.02
C57L/J f 738.0 20.9   8 7.37 0.0282 700.0, 766.0 0.23
C57L/J m 734.0 26.7   8 9.44 0.0364 686.0, 763.0 -0.36
CBA/J f 745.0 43.5   7 16.4 0.0584 657.0, 792.0 0.46
CBA/J m 768.0 18.8   8 6.65 0.0245 746.0, 796.0 0.6
DBA/2J f 712.0 15.6   8 5.53 0.022 686.0, 733.0 -0.6
DBA/2J m 733.0 34.7   8 12.3 0.0473 662.0, 772.0 -0.39
FVB/NJ f 770.0 32.7   8 11.5 0.0424 727.0, 816.0 1.27
FVB/NJ m 781.0 20.7   7 7.83 0.0265 756.0, 813.0 0.97
KK/HlJ f 728.0 17.4   8 6.14 0.0239 693.0, 749.0 -0.09
KK/HlJ m 747.0 27.9   8 9.87 0.0374 700.0, 789.0 0.01
LP/J f 726.0 50.6   6 20.7 0.0696 664.0, 775.0 -0.15
LP/J m 777.0 49.3   8 17.4 0.0635 707.0, 852.0 0.86
MRL/MpJ f 726.0 27.0   6 11.0 0.0372 684.0, 752.0 -0.15
MRL/MpJ m 757.0 25.9   8 9.16 0.0342 705.0, 780.0 0.29
NOD.B10Sn-H2b/J f 801.0 33.4   6 13.6 0.0416 761.0, 851.0 2.27
NOD.B10Sn-H2b/J m 785.0 25.2   4 12.6 0.032 758.0, 816.0 1.09
NON/ShiLtJ f 714.0 18.7   8 6.62 0.0262 686.0, 746.0 -0.54
NON/ShiLtJ m 707.0 29.8   8 10.5 0.0422 672.0, 755.0 -1.13
NZO/HlLtJ f 737.0 42.3   8 15.0 0.0575 645.0, 772.0 0.2
NZO/HlLtJ m 761.0 21.5   7 8.14 0.0283 741.0, 797.0 0.4
NZW/LacJ f 688.0 72.5   8 25.6 0.105 563.0, 796.0 -1.38
NZW/LacJ m 709.0 77.6   7 29.3 0.109 563.0, 775.0 -1.07
P/J f 751.0 19.2   5 8.58 0.0255 720.0, 768.0 0.65
P/J m 770.0 17.1   7 6.45 0.0222 744.0, 797.0 0.66
PL/J f 744.0 36.5   10 11.6 0.0492 688.0, 788.0 0.43
PL/J m 742.0 36.5   5 16.3 0.0493 696.0, 780.0 -0.13
RIIIS/J f 672.0 98.4   8 34.8 0.146 529.0, 782.0 -1.89
RIIIS/J m 657.0 59.8   7 22.6 0.0911 567.0, 750.0 -2.55
SJL/J f 699.0 44.5   8 15.7 0.0636 642.0, 763.0 -1.02
SJL/J m 778.0 16.7   8 5.9 0.0215 758.0, 808.0 0.89
SM/J f 744.0 27.3   8 9.65 0.0367 699.0, 774.0 0.43
SM/J m 764.0 12.9   8 4.56 0.0169 744.0, 778.0 0.49
SWR/J f 743.0 39.5   8 14.0 0.0532 692.0, 803.0 0.4
SWR/J m 722.0 51.1   8 18.1 0.0708 643.0, 816.0 -0.7


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 709.875 14.5431 738.4784 681.2716
129S1/SvImJ m 753.1429 15.5472 783.7212 722.5646
A/J f 723.25 14.5431 751.8534 694.6466
A/J m 703.25 14.5431 731.8534 674.6466
AKR/J f 781.5 14.5431 810.1034 752.8966
AKR/J m 766.1429 15.5472 796.7212 735.5646
BALB/cByJ f 696.8571 15.5472 727.4354 666.2788
BALB/cByJ m 672.75 14.5431 701.3534 644.1466
BUB/BnJ f 790.7143 15.5472 821.2926 760.136
BUB/BnJ m 787.2857 15.5472 817.864 756.7074
C3H/HeJ f 744.375 14.5431 772.9784 715.7716
C3H/HeJ m 807.8571 15.5472 838.4354 777.2788
C57BL/10J f 711.4286 15.5472 742.0069 680.8503
C57BL/10J m 760.125 14.5431 788.7284 731.5216
C57BL/6J f 735.25 14.5431 763.8534 706.6466
C57BL/6J m 753.5 14.5431 782.1034 724.8966
C57BLKS/J f 677.625 14.5431 706.2284 649.0216
C57BLKS/J m 720.0 15.5472 750.5783 689.4217
C57BR/cdJ f 728.8571 15.5472 759.4354 698.2788
C57BR/cdJ m 745.8571 15.5472 776.4354 715.2788
C57L/J f 738.5 14.5431 767.1034 709.8966
C57L/J m 734.25 14.5431 762.8534 705.6466
CBA/J f 744.7143 15.5472 775.2926 714.136
CBA/J m 768.25 14.5431 796.8534 739.6466
DBA/2J f 711.5 14.5431 740.1034 682.8966
DBA/2J m 733.25 14.5431 761.8534 704.6466
FVB/NJ f 770.5 14.5431 799.1034 741.8966
FVB/NJ m 780.7143 15.5472 811.2926 750.136
KK/HlJ f 727.625 14.5431 756.2284 699.0216
KK/HlJ m 746.875 14.5431 775.4784 718.2716
LP/J f 726.3333 16.7929 759.3617 693.305
LP/J m 776.625 14.5431 805.2284 748.0216
MRL/MpJ f 726.3333 16.7929 759.3617 693.305
MRL/MpJ m 757.125 14.5431 785.7284 728.5216
NOD.B10Sn-H2b/J f 801.1667 16.7929 834.195 768.1383
NOD.B10Sn-H2b/J m 785.0 20.567 825.4513 744.5487
NON/ShiLtJ f 714.375 14.5431 742.9784 685.7716
NON/ShiLtJ m 707.25 14.5431 735.8534 678.6466
NZO/HlLtJ f 736.625 14.5431 765.2284 708.0216
NZO/HlLtJ m 761.0 15.5472 791.5783 730.4217
NZW/LacJ f 687.5 14.5431 716.1034 658.8966
NZW/LacJ m 709.4286 15.5472 740.0069 678.8503
P/J f 751.2 18.3957 787.3807 715.0193
P/J m 769.5714 15.5472 800.1497 738.9931
PL/J f 743.5 13.0077 769.0836 717.9164
PL/J m 742.0 18.3957 778.1807 705.8193
RIIIS/J f 671.625 14.5431 700.2284 643.0216
RIIIS/J m 656.5714 15.5472 687.1497 625.9931
SJL/J f 698.75 14.5431 727.3534 670.1466
SJL/J m 777.875 14.5431 806.4784 749.2716
SM/J f 744.0 14.5431 772.6034 715.3966
SM/J m 763.625 14.5431 792.2284 735.0216
SWR/J f 742.75 14.5431 771.3534 714.1466
SWR/J m 722.375 14.5431 750.9784 693.7716


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 731.5089 10.6444 752.4445 710.5734
A/J both 713.25 10.2835 733.4756 693.0244
AKR/J both 773.8214 10.6444 794.757 752.8859
BALB/cByJ both 684.8036 10.6444 705.7391 663.868
BUB/BnJ both 789.0 10.9935 810.6221 767.3779
C3H/HeJ both 776.1161 10.6444 797.0516 755.1805
C57BL/10J both 735.7768 10.6444 756.7123 714.8413
C57BL/6J both 744.375 10.2835 764.6006 724.1494
C57BLKS/J both 698.8125 10.6444 719.748 677.877
C57BR/cdJ both 737.3571 10.9935 758.9793 715.735
C57L/J both 736.375 10.2835 756.6006 716.1494
CBA/J both 756.4821 10.6444 777.4177 735.5466
DBA/2J both 722.375 10.2835 742.6006 702.1494
FVB/NJ both 775.6071 10.6444 796.5427 754.6716
KK/HlJ both 737.25 10.2835 757.4756 717.0244
LP/J both 751.4792 11.1075 773.3254 729.633
MRL/MpJ both 741.7292 11.1075 763.5754 719.883
NOD.B10Sn-H2b/J both 793.0833 13.2759 819.1945 766.9721
NON/ShiLtJ both 710.8125 10.2835 731.0381 690.5869
NZO/HlLtJ both 748.8125 10.6444 769.748 727.877
NZW/LacJ both 698.4643 10.6444 719.3998 677.5288
P/J both 760.3857 12.0428 784.0716 736.6999
PL/J both 742.75 11.265 764.9061 720.5939
RIIIS/J both 664.0982 10.6444 685.0337 643.1627
SJL/J both 738.3125 10.2835 758.5381 718.0869
SM/J both 753.8125 10.2835 774.0381 733.5869
SWR/J both 732.5625 10.2835 752.7881 712.3369




  GWAS USING LINEAR MIXED MODELS