Project measure / variable:   Yuan3   BUN_M12

ID, description, units MPD:24482   BUN_M12   blood urea nitrogen (plasma BUN)   [mg/dL]  at age 12mo  
Data set, strains Yuan3   inbred   31 strains     sex: both     age: 52wks
Procedure metabolic panel
Ontology mappings

  STRAIN COMPARISON PLOT
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Yuan3 - blood urea nitrogen (plasma BUN) at age 12mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains30 strains
Mean of the strain means23.1   mg/dL 23.7   mg/dL
Median of the strain means23.0   mg/dL 23.4   mg/dL
SD of the strain means± 3.23 ± 3.47
Coefficient of variation (CV)0.140 0.147
Min–max range of strain means16.0   –   29.3   mg/dL 18.6   –   32.8   mg/dL
Mean sample size per strain6.0   mice 5.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 208.0402 208.0402 15.8911 0.0001
strain 23 2214.6818 96.2905 7.3551 < 0.0001
sex:strain 23 771.0707 33.5248 2.5608 0.0002
Residuals 262 3430.0008 13.0916


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 20.5 3.59   8 1.27 0.175 15.0, 26.0 -0.79
129S1/SvImJ m 23.6 1.41   8 0.498 0.0596 22.0, 26.0 -0.03
A/J f 24.2 3.92   6 1.6 0.162 20.0, 31.0 0.35
A/J m 23.4 1.51   8 0.532 0.0644 22.0, 26.0 -0.09
AKR/J m 21.0 1.73   3 1.0 0.0825 19.0, 22.0 -0.78
BALB/cByJ m 21.0 3.06   7 1.15 0.145 18.0, 27.0 -0.78
BTBR T+ Itpr3tf/J f 21.4 2.07   8 0.73 0.0966 19.0, 25.0 -0.52
BTBR T+ Itpr3tf/J m 23.3 4.54   7 1.71 0.195 20.0, 33.0 -0.12
BUB/BnJ f 28.2 2.28   5 1.02 0.0809 26.0, 31.0 1.59
BUB/BnJ m 26.6 9.07   7 3.43 0.341 18.0, 43.0 0.83
C3H/HeJ f 26.0 0.0   1   0.0 0.0 26.0, 26.0 0.91
C3H/HeJ m 24.2 1.47   6 0.601 0.0609 23.0, 26.0 0.14
C57BL/10J f 27.0 6.11   7 2.31 0.226 21.0, 39.0 1.22
C57BL/10J m 23.0 2.71   7 1.02 0.118 20.0, 28.0 -0.2
C57BL/6J f 26.8 2.79   6 1.14 0.104 22.0, 29.0 1.16
C57BL/6J m 26.2 2.55   8 0.901 0.0971 22.0, 30.0 0.72
C57BLKS/J f 20.9 2.27   7 0.857 0.109 19.0, 25.0 -0.67
C57BLKS/J m 18.8 3.37   6 1.38 0.179 16.0, 25.0 -1.41
C57BR/cdJ f 21.3 3.33   6 1.36 0.156 16.0, 26.0 -0.55
C57BR/cdJ m 22.3 1.15   3 0.667 0.0517 21.0, 23.0 -0.41
C57L/J f 16.0 0.707   5 0.316 0.0442 15.0, 17.0 -2.19
C57L/J m 19.0 1.73   3 1.0 0.0912 17.0, 20.0 -1.36
CAST/EiJ f 23.7 3.78   6 1.54 0.16 19.0, 30.0 0.2
CBA/J f 18.2 2.77   5 1.24 0.152 14.0, 21.0 -1.51
CBA/J m 18.6 2.5   8 0.885 0.134 16.0, 24.0 -1.47
DBA/2J f 22.8 1.72   6 0.703 0.0754 20.0, 25.0 -0.08
DBA/2J m 25.6 3.78   7 1.43 0.148 21.0, 32.0 0.54
FVB/NJ f 23.6 3.81   8 1.35 0.161 19.0, 30.0 0.17
FVB/NJ m 19.8 4.21   5 1.88 0.212 17.0, 27.0 -1.13
KK/HlJ f 17.7 4.48   12 1.29 0.254 14.0, 31.0 -1.66
KK/HlJ m 20.4 3.21   7 1.21 0.157 17.0, 27.0 -0.95
LP/J f 22.9 1.95   7 0.738 0.0854 20.0, 26.0 -0.05
LP/J m 21.8 3.99   8 1.41 0.183 17.0, 30.0 -0.55
MRL/MpJ f 21.0 4.72   8 1.67 0.225 17.0, 32.0 -0.64
MRL/MpJ m 29.0 9.67   6 3.95 0.334 19.0, 44.0 1.52
NOD.B10Sn-H2b/J f 20.7 2.98   7 1.13 0.144 17.0, 25.0 -0.73
NOD.B10Sn-H2b/J m 21.9 1.13   8 0.398 0.0515 20.0, 23.0 -0.52
NON/ShiLtJ f 29.3 4.82   7 1.82 0.165 21.0, 36.0 1.93
NON/ShiLtJ m 29.0 0.0   1   0.0 0.0 29.0, 29.0 1.52
NZO/HlLtJ f 21.0 1.26   6 0.516 0.0602 19.0, 22.0 -0.64
NZO/HlLtJ m 26.6 5.64   5 2.52 0.212 21.0, 36.0 0.83
NZW/LacJ f 21.1 1.89   8 0.666 0.0892 18.0, 24.0 -0.61
NZW/LacJ m 24.9 2.03   8 0.718 0.0816 22.0, 28.0 0.34
P/J f 25.8 1.47   6 0.601 0.057 24.0, 28.0 0.85
P/J m 27.1 3.89   7 1.47 0.143 23.0, 35.0 0.98
PL/J f 20.0 1.1   6 0.447 0.0548 19.0, 22.0 -0.95
PL/J m 19.7 2.07   6 0.843 0.105 17.0, 22.0 -1.15
PWD/PhJ f 24.2 1.6   6 0.654 0.0663 22.0, 26.0 0.35
PWD/PhJ m 32.8 5.25   4 2.63 0.16 28.0, 40.0 2.62
RIIIS/J f 27.0 8.43   5 3.77 0.312 20.0, 40.0 1.22
RIIIS/J m 21.0 0.0   1   0.0 0.0 21.0, 21.0 -0.78
SJL/J f 25.0 2.58   4 1.29 0.103 22.0, 28.0 0.6
SJL/J m 25.2 3.23   9 1.08 0.128 19.0, 29.0 0.43
SM/J f 23.1 3.39   7 1.28 0.146 18.0, 28.0 0.01
SM/J m 28.5 1.87   6 0.764 0.0656 26.0, 31.0 1.38
SWR/J f 23.0 0.0   1   0.0 0.0 23.0, 23.0 -0.02
SWR/J m 23.7 2.08   3 1.2 0.088 22.0, 26.0 0.0
WSB/EiJ f 26.5 2.12   2   1.5 0.08 25.0, 28.0 1.06
WSB/EiJ m 23.3 0.577   3 0.333 0.0247 23.0, 24.0 -0.12


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 20.5 1.2792 23.0189 17.9811
129S1/SvImJ m 23.625 1.2792 26.1439 21.1061
A/J f 24.1667 1.4771 27.0752 21.2581
A/J m 23.375 1.2792 25.8939 20.8561
BTBR T+ Itpr3tf/J f 21.375 1.2792 23.8939 18.8561
BTBR T+ Itpr3tf/J m 23.2857 1.3676 25.9785 20.5929
BUB/BnJ f 28.2 1.6181 31.3862 25.0138
BUB/BnJ m 26.5714 1.3676 29.2642 23.8786
C57BL/10J f 27.0 1.3676 29.6928 24.3072
C57BL/10J m 23.0 1.3676 25.6928 20.3072
C57BL/6J f 26.8333 1.4771 29.7419 23.9248
C57BL/6J m 26.25 1.2792 28.7689 23.7311
C57BLKS/J f 20.8571 1.3676 23.55 18.1643
C57BLKS/J m 18.8333 1.4771 21.7419 15.9248
C57BR/cdJ f 21.3333 1.4771 24.2419 18.4248
C57BR/cdJ m 22.3333 2.089 26.4467 18.22
C57L/J f 16.0 1.6181 19.1862 12.8138
C57L/J m 19.0 2.089 23.1133 14.8867
CBA/J f 18.2 1.6181 21.3862 15.0138
CBA/J m 18.625 1.2792 21.1439 16.1061
DBA/2J f 22.8333 1.4771 25.7419 19.9248
DBA/2J m 25.5714 1.3676 28.2642 22.8786
FVB/NJ f 23.625 1.2792 26.1439 21.1061
FVB/NJ m 19.8 1.6181 22.9862 16.6138
KK/HlJ f 17.6667 1.0445 19.7233 15.61
KK/HlJ m 20.4286 1.3676 23.1214 17.7358
LP/J f 22.8571 1.3676 25.55 20.1643
LP/J m 21.75 1.2792 24.2689 19.2311
MRL/MpJ f 21.0 1.2792 23.5189 18.4811
MRL/MpJ m 29.0 1.4771 31.9086 26.0914
NOD.B10Sn-H2b/J f 20.7143 1.3676 23.4071 18.0215
NOD.B10Sn-H2b/J m 21.875 1.2792 24.3939 19.3561
NZO/HlLtJ f 21.0 1.4771 23.9086 18.0914
NZO/HlLtJ m 26.6 1.6181 29.7862 23.4138
NZW/LacJ f 21.125 1.2792 23.6439 18.6061
NZW/LacJ m 24.875 1.2792 27.3939 22.3561
P/J f 25.8333 1.4771 28.7419 22.9248
P/J m 27.1429 1.3676 29.8357 24.45
PL/J f 20.0 1.4771 22.9086 17.0914
PL/J m 19.6667 1.4771 22.5752 16.7581
PWD/PhJ f 24.1667 1.4771 27.0752 21.2581
PWD/PhJ m 32.75 1.8091 36.3123 29.1877
SJL/J f 25.0 1.8091 28.5623 21.4377
SJL/J m 25.2222 1.2061 27.5971 22.8474
SM/J f 23.1429 1.3676 25.8357 20.45
SM/J m 28.5 1.4771 31.4086 25.5914
WSB/EiJ f 26.5 2.5585 31.5378 21.4622
WSB/EiJ m 23.3333 2.089 27.4467 19.22


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 22.0625 0.9046 23.8436 20.2814
A/J both 23.7708 0.977 25.6947 21.847
BTBR T+ Itpr3tf/J both 22.3304 0.9363 24.174 20.4867
BUB/BnJ both 27.3857 1.0593 29.4716 25.2999
C57BL/10J both 25.0 0.967 26.9041 23.0959
C57BL/6J both 26.5417 0.977 28.4655 24.6178
C57BLKS/J both 19.8452 1.0065 21.8271 17.8634
C57BR/cdJ both 21.8333 1.2792 24.3522 19.3144
C57L/J both 17.5 1.3212 20.1015 14.8985
CBA/J both 18.4125 1.0314 20.4433 16.3817
DBA/2J both 24.2024 1.0065 26.1842 22.2205
FVB/NJ both 21.7125 1.0314 23.7433 19.6817
KK/HlJ both 19.0476 0.8604 20.7418 17.3534
LP/J both 22.3036 0.9363 24.1472 20.4599
MRL/MpJ both 25.0 0.977 26.9238 23.0762
NOD.B10Sn-H2b/J both 21.2946 0.9363 23.1383 19.451
NZO/HlLtJ both 23.8 1.0955 25.9571 21.6429
NZW/LacJ both 23.0 0.9046 24.7811 21.2189
P/J both 26.4881 1.0065 28.47 24.5062
PL/J both 19.8333 1.0445 21.89 17.7767
PWD/PhJ both 28.4583 1.1678 30.7578 26.1589
SJL/J both 25.1111 1.0871 27.2518 22.9705
SM/J both 25.8214 1.0065 27.8033 23.8396
WSB/EiJ both 24.9167 1.6515 28.1685 21.6648




  GWAS USING LINEAR MIXED MODELS