Project measure / variable:   Yuan3   TP_M18

ID, description, units MPD:24458   TP_M18   total protein (plasma TP)   [g/dL]  at age 18mo  
Data set, strains Yuan3   inbred   29 strains     sex: both     age: 78wks
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  STRAIN COMPARISON PLOT
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Yuan3 - total protein (plasma TP) at age 18mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains25 strains
Mean of the strain means6.20   g/dL 6.18   g/dL
Median of the strain means6.30   g/dL 6.26   g/dL
SD of the strain means± 0.460 ± 0.451
Coefficient of variation (CV)0.0743 0.0730
Min–max range of strain means5.23   –   7.16   g/dL 4.95   –   6.83   g/dL
Mean sample size per strain7.0   mice 6.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0124 0.0124 0.0658 0.7977
strain 23 39.3714 1.7118 9.0758 < 0.0001
sex:strain 23 16.2161 0.705 3.7381 < 0.0001
Residuals 281 53.0 0.1886


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 6.83 0.222   4 0.111 0.0325 6.6, 7.1 1.38
129S1/SvImJ m 6.44 0.573   8 0.203 0.089 5.6, 7.5 0.57
A/J f 6.75 0.273   8 0.0964 0.0404 6.4, 7.2 1.2
BALB/cByJ f 6.11 0.544   8 0.192 0.0889 5.0, 6.7 -0.19
BALB/cByJ m 6.58 0.327   5 0.146 0.0497 6.0, 6.8 0.88
BTBR T+ Itpr3tf/J f 6.45 0.407   8 0.144 0.0631 5.9, 6.9 0.55
BTBR T+ Itpr3tf/J m 6.04 0.428   5 0.191 0.0708 5.8, 6.8 -0.31
BUB/BnJ f 5.91 0.196   8 0.0693 0.0331 5.7, 6.3 -0.62
BUB/BnJ m 5.5 0.167   6 0.0683 0.0304 5.3, 5.7 -1.51
C3H/HeJ f 6.11 0.47   8 0.166 0.077 5.5, 7.0 -0.19
C3H/HeJ m 6.3 0.2   7 0.0756 0.0317 6.0, 6.5 0.26
C57BL/10J f 6.3 0.316   5 0.141 0.0502 6.0, 6.8 0.22
C57BL/10J m 6.2 0.0   1   0.0 0.0 6.2, 6.2 0.04
C57BL/6J f 6.13 0.236   7 0.0892 0.0385 5.8, 6.5 -0.15
C57BL/6J m 6.52 0.214   6 0.0872 0.0328 6.3, 6.9 0.75
C57BLKS/J f 5.37 0.243   7 0.0918 0.0452 5.1, 5.7 -1.8
C57BR/cdJ f 6.11 0.344   8 0.122 0.0563 5.8, 6.8 -0.19
C57BR/cdJ m 5.72 0.462   6 0.189 0.0809 4.9, 6.3 -1.02
C57L/J f 6.63 0.431   7 0.163 0.065 6.0, 7.1 0.94
C57L/J m 6.03 0.216   6 0.0882 0.0358 5.7, 6.3 -0.34
CBA/J f 6.35 0.22   8 0.0779 0.0347 6.0, 6.6 0.33
CBA/J m 6.48 0.16   6 0.0654 0.0247 6.2, 6.7 0.66
DBA/2J f 5.5 0.542   7 0.205 0.0985 4.9, 6.2 -1.51
DBA/2J m 6.14 0.403   8 0.143 0.0657 5.4, 6.4 -0.09
FVB/NJ f 6.44 0.297   8 0.105 0.0462 6.0, 6.9 0.53
KK/HlJ f 6.43 0.575   6 0.235 0.0894 5.9, 7.3 0.51
KK/HlJ m 6.69 0.463   7 0.175 0.0693 6.1, 7.4 1.13
LP/J f 6.69 0.474   7 0.179 0.0709 6.0, 7.3 1.07
LP/J m 6.28 0.0983   6 0.0401 0.0156 6.2, 6.4 0.22
MRL/MpJ f 6.03 0.831   6 0.339 0.138 4.9, 7.3 -0.36
MRL/MpJ m 6.0 0.444   8 0.157 0.074 5.1, 6.5 -0.4
NOD.B10Sn-H2b/J f 6.33 0.442   7 0.167 0.0699 5.7, 6.9 0.29
NOD.B10Sn-H2b/J m 6.67 0.242   6 0.0989 0.0363 6.5, 7.1 1.08
NON/ShiLtJ f 5.77 0.579   15 0.149 0.1 4.9, 6.7 -0.93
NON/ShiLtJ m 5.94 0.244   7 0.0922 0.0411 5.6, 6.3 -0.54
NZO/HlLtJ f 5.23 0.666   3 0.384 0.127 4.5, 5.8 -2.1
NZW/LacJ f 6.35 0.901   8 0.318 0.142 4.4, 7.0 0.33
NZW/LacJ m 6.83 0.407   7 0.154 0.0596 6.3, 7.6 1.44
P/J f 6.36 0.586   5 0.262 0.0921 5.8, 7.2 0.35
P/J m 4.95 0.387   4 0.194 0.0782 4.6, 5.5 -2.73
PL/J f 5.92 0.417   6 0.17 0.0704 5.2, 6.3 -0.6
PL/J m 5.94 0.288   5 0.129 0.0485 5.5, 6.3 -0.54
PWD/PhJ f 6.23 0.373   7 0.141 0.0599 5.8, 6.9 0.07
PWD/PhJ m 6.44 0.529   8 0.187 0.0822 5.9, 7.1 0.57
RIIIS/J f 6.31 0.168   7 0.0634 0.0265 6.1, 6.6 0.25
RIIIS/J m 6.03 0.263   7 0.0993 0.0436 5.7, 6.5 -0.34
SJL/J f 5.75 0.593   8 0.21 0.103 4.7, 6.7 -0.97
SJL/J m 6.47 0.446   7 0.169 0.0689 5.8, 7.0 0.64
SM/J f 6.73 0.243   7 0.0918 0.0361 6.4, 7.1 1.16
SM/J m 6.26 0.777   5 0.347 0.124 4.9, 6.8 0.17
SWR/J f 7.16 0.404   7 0.153 0.0564 6.6, 7.5 2.09
SWR/J m 6.72 0.214   6 0.0872 0.0318 6.4, 7.0 1.19
WSB/EiJ f 5.43 0.198   8 0.0701 0.0365 5.1, 5.7 -1.67
WSB/EiJ m 5.37 0.163   6 0.0667 0.0304 5.1, 5.6 -1.8


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 6.825 0.2171 7.2524 6.3976
129S1/SvImJ m 6.4375 0.1535 6.7397 6.1353
BALB/cByJ f 6.1125 0.1535 6.4147 5.8103
BALB/cByJ m 6.58 0.1942 6.9623 6.1977
BTBR T+ Itpr3tf/J f 6.45 0.1535 6.7522 6.1478
BTBR T+ Itpr3tf/J m 6.04 0.1942 6.4223 5.6577
BUB/BnJ f 5.9125 0.1535 6.2147 5.6103
BUB/BnJ m 5.5 0.1773 5.849 5.151
C3H/HeJ f 6.1125 0.1535 6.4147 5.8103
C3H/HeJ m 6.3 0.1641 6.6231 5.9769
C57BL/6J f 6.1286 0.1641 6.4517 5.8055
C57BL/6J m 6.5167 0.1773 6.8657 6.1677
C57BR/cdJ f 6.1125 0.1535 6.4147 5.8103
C57BR/cdJ m 5.7167 0.1773 6.0657 5.3677
C57L/J f 6.6286 0.1641 6.9517 6.3055
C57L/J m 6.0333 0.1773 6.3823 5.6843
CBA/J f 6.35 0.1535 6.6522 6.0478
CBA/J m 6.4833 0.1773 6.8323 6.1343
DBA/2J f 5.5 0.1641 5.8231 5.1769
DBA/2J m 6.1375 0.1535 6.4397 5.8353
KK/HlJ f 6.4333 0.1773 6.7823 6.0843
KK/HlJ m 6.6857 0.1641 7.0088 6.3626
LP/J f 6.6857 0.1641 7.0088 6.3626
LP/J m 6.2833 0.1773 6.6323 5.9343
MRL/MpJ f 6.0333 0.1773 6.3823 5.6843
MRL/MpJ m 6.0 0.1535 6.3022 5.6978
NOD.B10Sn-H2b/J f 6.3286 0.1641 6.6517 6.0055
NOD.B10Sn-H2b/J m 6.6667 0.1773 7.0157 6.3177
NON/ShiLtJ f 5.7733 0.1121 5.9941 5.5526
NON/ShiLtJ m 5.9429 0.1641 6.266 5.6197
NZW/LacJ f 6.35 0.1535 6.6522 6.0478
NZW/LacJ m 6.8286 0.1641 7.1517 6.5055
P/J f 6.36 0.1942 6.7423 5.9777
P/J m 4.95 0.2171 5.3774 4.5226
PL/J f 5.9167 0.1773 6.2657 5.5677
PL/J m 5.94 0.1942 6.3223 5.5577
PWD/PhJ f 6.2286 0.1641 6.5517 5.9055
PWD/PhJ m 6.4375 0.1535 6.7397 6.1353
RIIIS/J f 6.3143 0.1641 6.6374 5.9912
RIIIS/J m 6.0286 0.1641 6.3517 5.7055
SJL/J f 5.75 0.1535 6.0522 5.4478
SJL/J m 6.4714 0.1641 6.7945 6.1483
SM/J f 6.7286 0.1641 7.0517 6.4055
SM/J m 6.26 0.1942 6.6423 5.8777
SWR/J f 7.1571 0.1641 7.4803 6.834
SWR/J m 6.7167 0.1773 7.0657 6.3677
WSB/EiJ f 5.425 0.1535 5.7272 5.1228
WSB/EiJ m 5.3667 0.1773 5.7157 5.0177


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 6.6312 0.133 6.893 6.3695
BALB/cByJ both 6.3462 0.1238 6.5899 6.1026
BTBR T+ Itpr3tf/J both 6.245 0.1238 6.4887 6.0013
BUB/BnJ both 5.7062 0.1173 5.9371 5.4754
C3H/HeJ both 6.2062 0.1124 6.4275 5.985
C57BL/6J both 6.3226 0.1208 6.5604 6.0848
C57BR/cdJ both 5.9146 0.1173 6.1454 5.6837
C57L/J both 6.331 0.1208 6.5688 6.0931
CBA/J both 6.4167 0.1173 6.6475 6.1858
DBA/2J both 5.8187 0.1124 6.04 5.5975
KK/HlJ both 6.5595 0.1208 6.7973 6.3217
LP/J both 6.4845 0.1208 6.7223 6.2467
MRL/MpJ both 6.0167 0.1173 6.2475 5.7858
NOD.B10Sn-H2b/J both 6.4976 0.1208 6.7354 6.2598
NON/ShiLtJ both 5.8581 0.0994 6.0538 5.6624
NZW/LacJ both 6.5893 0.1124 6.8105 6.3681
P/J both 5.655 0.1457 5.9417 5.3683
PL/J both 5.9283 0.1315 6.1872 5.6695
PWD/PhJ both 6.333 0.1124 6.5543 6.1118
RIIIS/J both 6.1714 0.1161 6.3999 5.943
SJL/J both 6.1107 0.1124 6.3319 5.8895
SM/J both 6.4943 0.1271 6.7446 6.244
SWR/J both 6.9369 0.1208 7.1747 6.6991
WSB/EiJ both 5.3958 0.1173 5.6267 5.165




  GWAS USING LINEAR MIXED MODELS