Project measure / variable:   Yuan3   TP_M12

ID, description, units MPD:24457   TP_M12   total protein (plasma TP)   [g/dL]  at age 12mo  
Data set, strains Yuan3   inbred   31 strains     sex: both     age: 52wks
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  STRAIN COMPARISON PLOT
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Yuan3 - total protein (plasma TP) at age 12mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested30 strains30 strains
Mean of the strain means6.08   g/dL 6.10   g/dL
Median of the strain means6.12   g/dL 6.01   g/dL
SD of the strain means± 0.388 ± 0.396
Coefficient of variation (CV)0.0638 0.0649
Min–max range of strain means4.95   –   6.82   g/dL 5.43   –   7.20   g/dL
Mean sample size per strain6.6   mice 6.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0786 0.0786 0.8361 0.3612
strain 23 33.141 1.4409 15.333 < 0.0001
sex:strain 23 10.1915 0.4431 4.7152 < 0.0001
Residuals 298 28.0044 0.094


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 5.92 0.446   8 0.158 0.0753 5.4, 6.8 -0.42
129S1/SvImJ m 5.78 0.388   8 0.137 0.0672 5.1, 6.1 -0.8
A/J f 6.17 0.427   7 0.161 0.0692 5.4, 6.8 0.22
A/J m 6.03 0.139   8 0.0491 0.023 5.8, 6.2 -0.17
AKR/J m 5.62 0.32   4 0.16 0.0569 5.3, 5.9 -1.21
BALB/cByJ f 6.2 0.0   1   0.0 0.0 6.2, 6.2 0.3
BALB/cByJ m 5.5 0.16   8 0.0567 0.0292 5.2, 5.7 -1.51
BTBR T+ Itpr3tf/J f 6.45 0.267   8 0.0945 0.0414 6.0, 6.7 0.95
BTBR T+ Itpr3tf/J m 5.97 0.33   7 0.125 0.0553 5.6, 6.5 -0.32
BUB/BnJ f 5.68 0.248   6 0.101 0.0437 5.4, 6.0 -1.04
BUB/BnJ m 5.76 0.388   9 0.129 0.0674 5.4, 6.5 -0.85
C3H/HeJ f 6.0 0.0   1   0.0 0.0 6.0, 6.0 -0.21
C3H/HeJ m 6.13 0.281   7 0.106 0.0459 5.7, 6.5 0.08
C57BL/10J f 6.06 0.35   8 0.124 0.0578 5.7, 6.6 -0.06
C57BL/10J m 5.97 0.214   7 0.0808 0.0358 5.7, 6.2 -0.32
C57BL/6J f 6.14 0.267   8 0.0944 0.0435 5.9, 6.5 0.15
C57BL/6J m 5.91 0.28   8 0.099 0.0474 5.5, 6.3 -0.47
C57BLKS/J f 5.64 0.207   8 0.073 0.0366 5.3, 5.9 -1.14
C57BLKS/J m 6.05 0.138   6 0.0563 0.0228 5.9, 6.3 -0.12
C57BR/cdJ f 6.15 0.251   8 0.0886 0.0408 5.7, 6.5 0.17
C57BR/cdJ m 6.4 0.361   3 0.208 0.0563 6.1, 6.8 0.76
C57L/J f 6.13 0.275   7 0.104 0.0449 5.7, 6.5 0.12
C57L/J m 6.16 0.256   8 0.0905 0.0415 5.8, 6.5 0.16
CAST/EiJ f 4.95 0.164   6 0.0671 0.0332 4.8, 5.2 -2.92
CBA/J f 6.08 0.183   8 0.0648 0.0302 5.8, 6.3 -0.01
CBA/J m 5.99 0.479   8 0.169 0.0801 5.3, 6.6 -0.27
DBA/2J f 5.3 0.141   6 0.0577 0.0267 5.1, 5.5 -2.02
DBA/2J m 5.91 0.291   7 0.11 0.0492 5.5, 6.2 -0.47
FVB/NJ f 5.96 0.233   8 0.0822 0.039 5.6, 6.4 -0.32
FVB/NJ m 6.76 0.257   7 0.0972 0.0381 6.5, 7.2 1.67
KK/HlJ f 5.71 0.41   12 0.118 0.0718 4.7, 6.0 -0.96
KK/HlJ m 5.97 0.111   7 0.0421 0.0186 5.8, 6.1 -0.32
LP/J f 5.91 0.121   7 0.0459 0.0205 5.8, 6.1 -0.45
LP/J m 5.85 0.262   8 0.0926 0.0448 5.3, 6.1 -0.63
MRL/MpJ f 6.74 0.292   8 0.103 0.0434 6.2, 7.2 1.69
MRL/MpJ m 6.53 0.48   6 0.196 0.0735 5.8, 7.3 1.09
NOD.B10Sn-H2b/J f 6.57 0.189   7 0.0714 0.0288 6.3, 6.9 1.25
NOD.B10Sn-H2b/J m 6.71 0.21   8 0.0743 0.0313 6.4, 7.0 1.55
NON/ShiLtJ f 6.07 0.373   7 0.141 0.0614 5.5, 6.6 -0.03
NON/ShiLtJ m 5.6 0.0   1   0.0 0.0 5.6, 5.6 -1.26
NZO/HlLtJ f 6.54 0.14   7 0.0528 0.0214 6.4, 6.8 1.18
NZO/HlLtJ m 7.2 0.474   5 0.212 0.0659 6.6, 7.9 2.78
NZW/LacJ f 6.14 0.141   8 0.0498 0.0229 5.9, 6.3 0.15
NZW/LacJ m 6.33 0.225   8 0.0796 0.0356 6.1, 6.8 0.59
P/J f 5.85 0.339   6 0.138 0.058 5.5, 6.4 -0.6
P/J m 5.43 0.616   7 0.233 0.113 4.7, 6.2 -1.69
PL/J f 6.34 0.251   7 0.0948 0.0395 6.0, 6.7 0.66
PL/J m 6.33 0.234   6 0.0955 0.0369 5.9, 6.6 0.59
PWD/PhJ f 6.03 0.175   6 0.0715 0.029 5.9, 6.3 -0.14
PWD/PhJ m 6.15 0.387   4 0.194 0.063 5.8, 6.7 0.13
RIIIS/J f 6.16 0.23   5 0.103 0.0374 5.9, 6.5 0.2
RIIIS/J m 5.8 0.0   1   0.0 0.0 5.8, 5.8 -0.75
SJL/J f 6.82 0.685   4 0.342 0.1 6.0, 7.6 1.9
SJL/J m 5.97 0.436   9 0.145 0.0731 5.1, 6.5 -0.32
SM/J f 6.49 0.227   7 0.0857 0.035 6.1, 6.8 1.05
SM/J m 6.6 0.2   7 0.0756 0.0303 6.3, 6.8 1.27
SWR/J f 6.1 0.0   1   0.0 0.0 6.1, 6.1 0.04
SWR/J m 6.17 0.0577   3 0.0333 0.00936 6.1, 6.2 0.18
WSB/EiJ f 6.19 0.189   8 0.0666 0.0305 6.0, 6.5 0.28
WSB/EiJ m 6.36 0.141   8 0.0498 0.0221 6.1, 6.5 0.66


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 5.925 0.1084 6.1383 5.7117
129S1/SvImJ m 5.775 0.1084 5.9883 5.5617
A/J f 6.1714 0.1159 6.3994 5.9434
A/J m 6.025 0.1084 6.2383 5.8117
BTBR T+ Itpr3tf/J f 6.45 0.1084 6.6633 6.2367
BTBR T+ Itpr3tf/J m 5.9714 0.1159 6.1994 5.7434
BUB/BnJ f 5.6833 0.1251 5.9296 5.437
BUB/BnJ m 5.7556 0.1022 5.9566 5.5545
C57BL/10J f 6.0625 0.1084 6.2758 5.8492
C57BL/10J m 5.9714 0.1159 6.1994 5.7434
C57BL/6J f 6.1375 0.1084 6.3508 5.9242
C57BL/6J m 5.9125 0.1084 6.1258 5.6992
C57BLKS/J f 5.6375 0.1084 5.8508 5.4242
C57BLKS/J m 6.05 0.1251 6.2963 5.8037
C57BR/cdJ f 6.15 0.1084 6.3633 5.9367
C57BR/cdJ m 6.4 0.177 6.7483 6.0517
C57L/J f 6.1286 0.1159 6.3566 5.9006
C57L/J m 6.1625 0.1084 6.3758 5.9492
CBA/J f 6.075 0.1084 6.2883 5.8617
CBA/J m 5.9875 0.1084 6.2008 5.7742
DBA/2J f 5.3 0.1251 5.5463 5.0537
DBA/2J m 5.9143 0.1159 6.1423 5.6863
FVB/NJ f 5.9625 0.1084 6.1758 5.7492
FVB/NJ m 6.7571 0.1159 6.9852 6.5291
KK/HlJ f 5.7083 0.0885 5.8825 5.5342
KK/HlJ m 5.9714 0.1159 6.1994 5.7434
LP/J f 5.9143 0.1159 6.1423 5.6863
LP/J m 5.85 0.1084 6.0633 5.6367
MRL/MpJ f 6.7375 0.1084 6.9508 6.5242
MRL/MpJ m 6.5333 0.1251 6.7796 6.287
NOD.B10Sn-H2b/J f 6.5714 0.1159 6.7994 6.3434
NOD.B10Sn-H2b/J m 6.7125 0.1084 6.9258 6.4992
NZO/HlLtJ f 6.5429 0.1159 6.7709 6.3148
NZO/HlLtJ m 7.2 0.1371 7.4698 6.9302
NZW/LacJ f 6.1375 0.1084 6.3508 5.9242
NZW/LacJ m 6.325 0.1084 6.5383 6.1117
P/J f 5.85 0.1251 6.0963 5.6037
P/J m 5.4286 0.1159 5.6566 5.2006
PL/J f 6.3429 0.1159 6.5709 6.1148
PL/J m 6.3333 0.1251 6.5796 6.087
PWD/PhJ f 6.0333 0.1251 6.2796 5.787
PWD/PhJ m 6.15 0.1533 6.4516 5.8484
SJL/J f 6.825 0.1533 7.1266 6.5234
SJL/J m 5.9667 0.1022 6.1678 5.7656
SM/J f 6.4857 0.1159 6.7137 6.2577
SM/J m 6.6 0.1159 6.828 6.372
WSB/EiJ f 6.1875 0.1084 6.4008 5.9742
WSB/EiJ m 6.3625 0.1084 6.5758 6.1492


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 5.85 0.0766 6.0008 5.6992
A/J both 6.0982 0.0793 6.2543 5.9421
BTBR T+ Itpr3tf/J both 6.2107 0.0793 6.3668 6.0546
BUB/BnJ both 5.7194 0.0808 5.8784 5.5605
C57BL/10J both 6.017 0.0793 6.1731 5.8609
C57BL/6J both 6.025 0.0766 6.1758 5.8742
C57BLKS/J both 5.8437 0.0828 6.0067 5.6808
C57BR/cdJ both 6.275 0.1038 6.4792 6.0708
C57L/J both 6.1455 0.0793 6.3016 5.9894
CBA/J both 6.0312 0.0766 6.1821 5.8804
DBA/2J both 5.6071 0.0853 5.775 5.4393
FVB/NJ both 6.3598 0.0793 6.5159 6.2037
KK/HlJ both 5.8399 0.0729 5.9833 5.6964
LP/J both 5.8821 0.0793 6.0383 5.726
MRL/MpJ both 6.6354 0.0828 6.7983 6.4725
NOD.B10Sn-H2b/J both 6.642 0.0793 6.7981 6.4859
NZO/HlLtJ both 6.8714 0.0897 7.0481 6.6948
NZW/LacJ both 6.2313 0.0766 6.3821 6.0804
P/J both 5.6393 0.0853 5.8071 5.4715
PL/J both 6.3381 0.0853 6.5059 6.1703
PWD/PhJ both 6.0917 0.0989 6.2864 5.897
SJL/J both 6.3958 0.0921 6.5771 6.2146
SM/J both 6.5429 0.0819 6.7041 6.3816
WSB/EiJ both 6.275 0.0766 6.4258 6.1242




  GWAS USING LINEAR MIXED MODELS