Project measure / variable:   Yuan3   LIP_M18

ID, description, units MPD:24408   LIP_M18   lipase (plasma LIP)   [U/L]  at age 18mo  
Data set, strains Yuan3   inbred   29 strains     sex: both     age: 78wks
Procedure metabolic panel
Ontology mappings

  STRAIN COMPARISON PLOT
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Yuan3 - lipase (plasma LIP) at age 18mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains25 strains
Mean of the strain means52.1   U/L 52.5   U/L
Median of the strain means52.8   U/L 52.8   U/L
SD of the strain means± 12.4 ± 14.9
Coefficient of variation (CV)0.238 0.284
Min–max range of strain means31.9   –   77.4   U/L 33.0   –   102   U/L
Mean sample size per strain7.0   mice 6.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 185.4009 185.4009 0.7261 0.3949
strain 23 47340.268 2058.2725 8.0615 < 0.0001
sex:strain 23 10429.8229 453.4706 1.7761 0.0173
Residuals 281 71745.3107 255.3214


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 52.8 6.38   5 2.85 0.121 48.0, 63.0 0.05
129S1/SvImJ m 52.8 19.7   8 6.95 0.373 32.0, 90.0 0.02
A/J f 61.8 31.2   8 11.0 0.505 34.0, 133.0 0.78
BALB/cByJ f 77.4 17.0   8 6.02 0.22 63.0, 117.0 2.03
BALB/cByJ m 59.4 8.56   5 3.83 0.144 46.0, 68.0 0.46
BTBR T+ Itpr3tf/J f 42.8 11.1   8 3.93 0.26 22.0, 56.0 -0.75
BTBR T+ Itpr3tf/J m 50.6 17.1   5 7.66 0.338 35.0, 77.0 -0.13
BUB/BnJ f 64.2 13.4   8 4.75 0.209 54.0, 95.0 0.97
BUB/BnJ m 59.0 5.69   6 2.32 0.0965 53.0, 68.0 0.44
C3H/HeJ f 34.2 8.33   8 2.94 0.243 20.0, 45.0 -1.45
C3H/HeJ m 43.4 10.9   7 4.12 0.251 30.0, 60.0 -0.61
C57BL/10J f 44.6 7.64   5 3.41 0.171 37.0, 57.0 -0.61
C57BL/10J m 33.0 0.0   1   0.0 0.0 33.0, 33.0 -1.31
C57BL/6J f 57.8 8.28   6 3.38 0.143 44.0, 67.0 0.46
C57BL/6J m 72.1 27.3   7 10.3 0.378 46.0, 122.0 1.32
C57BLKS/J f 53.3 11.2   7 4.25 0.211 32.0, 65.0 0.09
C57BR/cdJ f 47.9 23.4   8 8.27 0.489 35.0, 105.0 -0.34
C57BR/cdJ m 66.8 58.7   6 24.0 0.879 36.0, 186.0 0.96
C57L/J f 54.9 14.8   8 5.23 0.27 28.0, 77.0 0.22
C57L/J m 48.7 10.1   6 4.12 0.207 32.0, 61.0 -0.25
CBA/J f 35.4 9.13   8 3.23 0.258 16.0, 45.0 -1.35
CBA/J m 42.5 4.68   6 1.91 0.11 36.0, 49.0 -0.67
DBA/2J f 51.3 5.91   7 2.23 0.115 46.0, 64.0 -0.07
DBA/2J m 38.0 14.0   8 4.94 0.368 24.0, 61.0 -0.97
FVB/NJ f 64.2 9.15   8 3.23 0.142 51.0, 75.0 0.97
KK/HlJ f 51.0 9.3   5 4.16 0.182 40.0, 65.0 -0.09
KK/HlJ m 64.7 11.8   7 4.48 0.183 51.0, 83.0 0.82
LP/J f 70.7 22.6   7 8.53 0.319 53.0, 119.0 1.49
LP/J m 53.8 9.11   6 3.72 0.169 43.0, 68.0 0.09
MRL/MpJ f 56.5 29.3   6 11.9 0.518 40.0, 116.0 0.35
MRL/MpJ m 53.8 9.97   8 3.52 0.185 43.0, 74.0 0.09
NOD.B10Sn-H2b/J f 75.3 21.8   7 8.24 0.289 40.0, 93.0 1.86
NOD.B10Sn-H2b/J m 102.0 20.4   6 8.35 0.2 70.0, 124.0 3.32
NON/ShiLtJ f 50.6 9.92   15 2.56 0.196 32.0, 66.0 -0.12
NON/ShiLtJ m 54.4 6.32   7 2.39 0.116 46.0, 62.0 0.13
NZO/HlLtJ f 34.3 2.08   3 1.2 0.0606 32.0, 36.0 -1.44
NZW/LacJ f 47.6 15.0   8 5.3 0.315 23.0, 61.0 -0.37
NZW/LacJ m 49.9 22.5   7 8.49 0.451 34.0, 100.0 -0.17
P/J f 62.6 13.0   5 5.81 0.208 45.0, 75.0 0.84
P/J m 38.2 6.29   4 3.15 0.164 31.0, 44.0 -0.96
PL/J f 40.0 9.01   6 3.68 0.225 27.0, 51.0 -0.98
PL/J m 37.4 1.52   5 0.678 0.0406 36.0, 39.0 -1.01
PWD/PhJ f 57.9 4.88   7 1.84 0.0843 51.0, 64.0 0.46
PWD/PhJ m 55.1 10.2   7 3.85 0.185 39.0, 71.0 0.18
RIIIS/J f 36.0 11.3   7 4.27 0.313 24.0, 53.0 -1.3
RIIIS/J m 34.0 5.69   7 2.15 0.167 27.0, 42.0 -1.24
SJL/J f 58.0 18.7   8 6.63 0.323 41.0, 88.0 0.47
SJL/J m 57.7 15.1   7 5.7 0.261 42.0, 79.0 0.35
SM/J f 31.9 5.34   7 2.02 0.168 24.0, 40.0 -1.63
SM/J m 47.6 21.9   5 9.79 0.46 29.0, 84.0 -0.33
SWR/J f 59.3 12.7   7 4.79 0.214 43.0, 77.0 0.58
SWR/J m 62.5 14.1   6 5.77 0.226 49.0, 90.0 0.67
WSB/EiJ f 38.0 2.93   8 1.04 0.077 31.0, 40.0 -1.14
WSB/EiJ m 34.7 2.8   6 1.15 0.0809 32.0, 39.0 -1.19


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 52.8 7.1459 66.8663 38.7337
129S1/SvImJ m 52.75 5.6494 63.8704 41.6296
BALB/cByJ f 77.375 5.6494 88.4954 66.2546
BALB/cByJ m 59.4 7.1459 73.4663 45.3337
BTBR T+ Itpr3tf/J f 42.75 5.6494 53.8704 31.6296
BTBR T+ Itpr3tf/J m 50.6 7.1459 64.6663 36.5337
BUB/BnJ f 64.25 5.6494 75.3704 53.1296
BUB/BnJ m 59.0 6.5233 71.8408 46.1592
C3H/HeJ f 34.25 5.6494 45.3704 23.1296
C3H/HeJ m 43.4286 6.0394 55.3168 31.5403
C57BL/6J f 57.8333 6.5233 70.6741 44.9926
C57BL/6J m 72.1429 6.0394 84.0311 60.2546
C57BR/cdJ f 47.875 5.6494 58.9954 36.7546
C57BR/cdJ m 66.8333 6.5233 79.6741 53.9926
C57L/J f 54.875 5.6494 65.9954 43.7546
C57L/J m 48.6667 6.5233 61.5074 35.8259
CBA/J f 35.375 5.6494 46.4954 24.2546
CBA/J m 42.5 6.5233 55.3408 29.6592
DBA/2J f 51.2857 6.0394 63.1739 39.3975
DBA/2J m 38.0 5.6494 49.1204 26.8796
KK/HlJ f 51.0 7.1459 65.0663 36.9337
KK/HlJ m 64.7143 6.0394 76.6025 52.8261
LP/J f 70.7143 6.0394 82.6025 58.8261
LP/J m 53.8333 6.5233 66.6741 40.9926
MRL/MpJ f 56.5 6.5233 69.3408 43.6592
MRL/MpJ m 53.75 5.6494 64.8704 42.6296
NOD.B10Sn-H2b/J f 75.2857 6.0394 87.1739 63.3975
NOD.B10Sn-H2b/J m 102.3333 6.5233 115.1741 89.4926
NON/ShiLtJ f 50.6 4.1257 58.7212 42.4788
NON/ShiLtJ m 54.4286 6.0394 66.3168 42.5403
NZW/LacJ f 47.625 5.6494 58.7454 36.5046
NZW/LacJ m 49.8571 6.0394 61.7454 37.9689
P/J f 62.6 7.1459 76.6663 48.5337
P/J m 38.25 7.9894 53.9767 22.5233
PL/J f 40.0 6.5233 52.8408 27.1592
PL/J m 37.4 7.1459 51.4663 23.3337
PWD/PhJ f 57.8571 6.0394 69.7454 45.9689
PWD/PhJ m 55.1429 6.0394 67.0311 43.2546
RIIIS/J f 36.0 6.0394 47.8882 24.1118
RIIIS/J m 34.0 6.0394 45.8882 22.1118
SJL/J f 58.0 5.6494 69.1204 46.8796
SJL/J m 57.7143 6.0394 69.6025 45.8261
SM/J f 31.8571 6.0394 43.7454 19.9689
SM/J m 47.6 7.1459 61.6663 33.5337
SWR/J f 59.2857 6.0394 71.1739 47.3975
SWR/J m 62.5 6.5233 75.3408 49.6592
WSB/EiJ f 38.0 5.6494 49.1204 26.8796
WSB/EiJ m 34.6667 6.5233 47.5074 21.8259


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 52.775 4.5547 61.7406 43.8094
BALB/cByJ both 68.3875 4.5547 77.3531 59.4219
BTBR T+ Itpr3tf/J both 46.675 4.5547 55.6406 37.7094
BUB/BnJ both 61.625 4.3148 70.1184 53.1316
C3H/HeJ both 38.8393 4.1349 46.9786 30.7
C57BL/6J both 64.9881 4.4449 73.7376 56.2386
C57BR/cdJ both 57.3542 4.3148 65.8475 48.8608
C57L/J both 51.7708 4.3148 60.2642 43.2775
CBA/J both 38.9375 4.3148 47.4309 30.4441
DBA/2J both 44.6429 4.1349 52.7822 36.5035
KK/HlJ both 57.8571 4.6781 67.0657 48.6486
LP/J both 62.2738 4.4449 71.0233 53.5243
MRL/MpJ both 55.125 4.3148 63.6184 46.6316
NOD.B10Sn-H2b/J both 88.8095 4.4449 97.559 80.06
NON/ShiLtJ both 52.5143 3.657 59.713 45.3156
NZW/LacJ both 48.7411 4.1349 56.8804 40.6018
P/J both 50.425 5.3594 60.9748 39.8752
PL/J both 38.7 4.8378 48.223 29.177
PWD/PhJ both 56.5 4.2705 64.9062 48.0938
RIIIS/J both 35.0 4.2705 43.4062 26.5938
SJL/J both 57.8571 4.1349 65.9965 49.7178
SM/J both 39.7286 4.6781 48.9372 30.52
SWR/J both 60.8929 4.4449 69.6424 52.1434
WSB/EiJ both 36.3333 4.3148 44.8267 27.84




  GWAS USING LINEAR MIXED MODELS