Project measure / variable:   Yuan3   LIP_M12

ID, description, units MPD:24407   LIP_M12   lipase (plasma LIP)   [U/L]  at age 12mo  
Data set, strains Yuan3   inbred   31 strains     sex: both     age: 52wks
Procedure metabolic panel
Ontology mappings

  STRAIN COMPARISON PLOT
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Yuan3 - lipase (plasma LIP) at age 12mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested30 strains30 strains
Mean of the strain means57.7   U/L 55.2   U/L
Median of the strain means56.9   U/L 54.1   U/L
SD of the strain means± 13.6 ± 15.3
Coefficient of variation (CV)0.236 0.277
Min–max range of strain means25.5   –   86.6   U/L 33.6   –   108   U/L
Mean sample size per strain6.4   mice 6.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2897.554 2897.554 14.4337 0.0002
strain 23 47662.4922 2072.2823 10.3227 < 0.0001
sex:strain 23 17144.144 745.3976 3.7131 < 0.0001
Residuals 291 58417.975 200.7491


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 57.1 6.36   8 2.25 0.111 49.0, 71.0 -0.04
129S1/SvImJ m 54.2 9.5   8 3.36 0.175 43.0, 69.0 -0.06
A/J f 61.4 15.8   5 7.08 0.258 47.0, 81.0 0.27
A/J m 58.8 29.8   8 10.5 0.507 38.0, 130.0 0.24
AKR/J m 39.5 8.35   4 4.17 0.211 27.0, 44.0 -1.03
BALB/cByJ f 56.0 0.0   1   0.0 0.0 56.0, 56.0 -0.12
BALB/cByJ m 51.4 5.37   8 1.9 0.105 44.0, 59.0 -0.25
BTBR T+ Itpr3tf/J f 55.2 6.71   8 2.37 0.122 45.0, 65.0 -0.18
BTBR T+ Itpr3tf/J m 52.6 4.69   7 1.77 0.0891 45.0, 58.0 -0.17
BUB/BnJ f 68.0 7.77   6 3.17 0.114 60.0, 80.0 0.76
BUB/BnJ m 58.3 16.1   9 5.37 0.276 44.0, 87.0 0.2
C3H/HeJ f 42.0 0.0   1   0.0 0.0 42.0, 42.0 -1.15
C3H/HeJ m 45.7 8.18   7 3.09 0.179 30.0, 54.0 -0.62
C57BL/10J f 44.8 9.74   8 3.44 0.218 32.0, 57.0 -0.95
C57BL/10J m 46.0 8.14   7 3.08 0.177 34.0, 60.0 -0.6
C57BL/6J f 74.3 12.0   7 4.55 0.162 57.0, 88.0 1.22
C57BL/6J m 57.4 8.99   8 3.18 0.157 47.0, 75.0 0.15
C57BLKS/J f 61.1 13.9   7 5.27 0.228 39.0, 84.0 0.25
C57BLKS/J m 60.5 4.37   6 1.78 0.0722 57.0, 69.0 0.35
C57BR/cdJ f 66.7 10.4   6 4.25 0.156 54.0, 80.0 0.66
C57BR/cdJ m 69.7 2.52   3 1.45 0.0361 67.0, 72.0 0.95
C57L/J f 53.4 6.85   7 2.59 0.128 43.0, 61.0 -0.31
C57L/J m 55.6 8.42   8 2.98 0.151 45.0, 67.0 0.03
CAST/EiJ f 25.5 9.2   6 3.76 0.361 20.0, 44.0 -2.36
CBA/J f 40.2 8.66   8 3.06 0.215 21.0, 47.0 -1.28
CBA/J m 36.1 5.62   8 1.99 0.155 25.0, 41.0 -1.25
DBA/2J f 61.7 22.4   6 9.13 0.363 39.0, 101.0 0.29
DBA/2J m 43.1 12.9   7 4.88 0.299 24.0, 63.0 -0.79
FVB/NJ f 69.5 11.0   8 3.91 0.159 50.0, 84.0 0.87
FVB/NJ m 63.5 12.5   8 4.41 0.197 46.0, 83.0 0.54
KK/HlJ f 68.9 19.9   12 5.73 0.288 42.0, 92.0 0.82
KK/HlJ m 63.1 15.2   7 5.74 0.24 38.0, 81.0 0.52
LP/J f 60.4 9.29   7 3.51 0.154 43.0, 70.0 0.2
LP/J m 48.0 8.33   8 2.95 0.174 35.0, 59.0 -0.47
MRL/MpJ f 55.8 11.1   8 3.91 0.199 38.0, 70.0 -0.14
MRL/MpJ m 64.2 35.7   6 14.6 0.557 39.0, 131.0 0.59
NOD.B10Sn-H2b/J f 86.6 8.04   7 3.04 0.0929 73.0, 97.0 2.12
NOD.B10Sn-H2b/J m 108.0 42.2   7 16.0 0.392 77.0, 198.0 3.45
NON/ShiLtJ f 49.6 8.42   7 3.18 0.17 38.0, 59.0 -0.59
NON/ShiLtJ m 63.0 0.0   1   0.0 0.0 63.0, 63.0 0.51
NZO/HlLtJ f 54.4 7.81   7 2.95 0.143 46.0, 66.0 -0.24
NZO/HlLtJ m 91.0 28.8   5 12.9 0.316 61.0, 120.0 2.34
NZW/LacJ f 74.8 8.8   8 3.11 0.118 63.0, 92.0 1.26
NZW/LacJ m 49.1 3.76   8 1.33 0.0765 45.0, 54.0 -0.4
P/J f 80.3 11.8   6 4.8 0.146 66.0, 98.0 1.66
P/J m 37.9 5.49   7 2.08 0.145 30.0, 46.0 -1.13
PL/J f 50.0 8.53   6 3.48 0.171 42.0, 62.0 -0.56
PL/J m 55.2 4.54   6 1.85 0.0822 48.0, 60.0 0.0
PWD/PhJ f 70.6 9.91   5 4.43 0.14 58.0, 85.0 0.95
PWD/PhJ m 54.0 25.3   4 12.7 0.469 34.0, 90.0 -0.08
RIIIS/J f 59.4 13.0   5 5.82 0.219 51.0, 82.0 0.13
RIIIS/J m 61.0 0.0   1   0.0 0.0 61.0, 61.0 0.38
SJL/J f 51.6 4.77   5 2.14 0.0925 48.0, 60.0 -0.45
SJL/J m 42.0 5.34   9 1.78 0.127 36.0, 53.0 -0.86
SM/J f 38.7 12.0   7 4.52 0.309 23.0, 61.0 -1.39
SM/J m 33.6 5.91   7 2.23 0.176 24.0, 42.0 -1.41
SWR/J f 36.0 0.0   1   0.0 0.0 36.0, 36.0 -1.59
SWR/J m 48.0 9.64   3 5.57 0.201 37.0, 55.0 -0.47
WSB/EiJ f 56.6 12.6   8 4.47 0.223 41.0, 76.0 -0.08
WSB/EiJ m 44.9 9.61   8 3.4 0.214 34.0, 62.0 -0.67


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 57.125 5.0094 66.9842 47.2658
129S1/SvImJ m 54.25 5.0094 64.1092 44.3908
A/J f 61.4 6.3364 73.871 48.929
A/J m 58.75 5.0094 68.6092 48.8908
BTBR T+ Itpr3tf/J f 55.25 5.0094 65.1092 45.3908
BTBR T+ Itpr3tf/J m 52.5714 5.3552 63.1113 42.0315
BUB/BnJ f 68.0 5.7843 79.3844 56.6156
BUB/BnJ m 58.3333 4.7229 67.6286 49.038
C57BL/10J f 44.75 5.0094 54.6092 34.8908
C57BL/10J m 46.0 5.3552 56.5399 35.4601
C57BL/6J f 74.2857 5.3552 84.8256 63.7458
C57BL/6J m 57.375 5.0094 67.2342 47.5158
C57BLKS/J f 61.1429 5.3552 71.6827 50.603
C57BLKS/J m 60.5 5.7843 71.8844 49.1156
C57BR/cdJ f 66.6667 5.7843 78.051 55.2823
C57BR/cdJ m 69.6667 8.1802 85.7666 53.5667
C57L/J f 53.4286 5.3552 63.9685 42.8887
C57L/J m 55.625 5.0094 65.4842 45.7658
CBA/J f 40.25 5.0094 50.1092 30.3908
CBA/J m 36.125 5.0094 45.9842 26.2658
DBA/2J f 61.6667 5.7843 73.051 50.2823
DBA/2J m 43.1429 5.3552 53.6827 32.603
FVB/NJ f 69.5 5.0094 79.3592 59.6408
FVB/NJ m 63.5 5.0094 73.3592 53.6408
KK/HlJ f 68.9167 4.0901 76.9666 60.8667
KK/HlJ m 63.1429 5.3552 73.6827 52.603
LP/J f 60.4286 5.3552 70.9685 49.8887
LP/J m 48.0 5.0094 57.8592 38.1408
MRL/MpJ f 55.75 5.0094 65.6092 45.8908
MRL/MpJ m 64.1667 5.7843 75.551 52.7823
NOD.B10Sn-H2b/J f 86.5714 5.3552 97.1113 76.0315
NOD.B10Sn-H2b/J m 107.7143 5.3552 118.2542 97.1744
NZO/HlLtJ f 54.4286 5.3552 64.9685 43.8887
NZO/HlLtJ m 91.0 6.3364 103.471 78.529
NZW/LacJ f 74.75 5.0094 84.6092 64.8908
NZW/LacJ m 49.125 5.0094 58.9842 39.2658
P/J f 80.3333 5.7843 91.7177 68.949
P/J m 37.8571 5.3552 48.397 27.3173
PL/J f 50.0 5.7843 61.3844 38.6156
PL/J m 55.1667 5.7843 66.551 43.7823
PWD/PhJ f 70.6 6.3364 83.071 58.129
PWD/PhJ m 54.0 7.0843 67.943 40.057
SJL/J f 51.6 6.3364 64.071 39.129
SJL/J m 42.0 4.7229 51.2953 32.7047
SM/J f 38.7143 5.3552 49.2542 28.1744
SM/J m 33.5714 5.3552 44.1113 23.0315
WSB/EiJ f 56.625 5.0094 66.4842 46.7658
WSB/EiJ m 44.875 5.0094 54.7342 35.0158


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 55.6875 3.5421 62.659 48.716
A/J both 60.075 4.0387 68.0237 52.1263
BTBR T+ Itpr3tf/J both 53.9107 3.6665 61.1269 46.6945
BUB/BnJ both 63.1667 3.7338 70.5152 55.8181
C57BL/10J both 45.375 3.6665 52.5912 38.1588
C57BL/6J both 65.8304 3.6665 73.0465 58.6142
C57BLKS/J both 60.8214 3.9413 68.5786 53.0643
C57BR/cdJ both 68.1667 5.0094 78.0258 58.3075
C57L/J both 54.5268 3.6665 61.743 47.3106
CBA/J both 38.1875 3.5421 45.159 31.216
DBA/2J both 52.4048 3.9413 60.1619 44.6476
FVB/NJ both 66.5 3.5421 73.4715 59.5285
KK/HlJ both 66.0298 3.3693 72.661 59.3986
LP/J both 54.2143 3.6665 61.4305 46.9981
MRL/MpJ both 59.9583 3.826 67.4884 52.4283
NOD.B10Sn-H2b/J both 97.1429 3.7867 104.5957 89.69
NZO/HlLtJ both 72.7143 4.1481 80.8784 64.5501
NZW/LacJ both 61.9375 3.5421 68.909 54.966
P/J both 59.0952 3.9413 66.8524 51.3381
PL/J both 52.5833 4.0901 60.6333 44.5334
PWD/PhJ both 62.3 4.7523 71.6532 52.9468
SJL/J both 46.8 3.9514 54.577 39.023
SM/J both 36.1429 3.7867 43.5957 28.69
WSB/EiJ both 50.75 3.5421 57.7215 43.7785




  GWAS USING LINEAR MIXED MODELS