Project measure / variable:   Yuan3   LIP_M06

ID, description, units MPD:24406   LIP_M06   lipase (plasma LIP)   [U/L]  at age 6mo  
Data set, strains Yuan3   inbred   31 strains     sex: both     age: 26wks
Procedure metabolic panel
Ontology mappings

  STRAIN COMPARISON PLOT
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Yuan3 - lipase (plasma LIP) at age 6mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains27 strains
Mean of the strain means64.3   U/L 59.4   U/L
Median of the strain means63.8   U/L 57.2   U/L
SD of the strain means± 15.0 ± 17.5
Coefficient of variation (CV)0.233 0.295
Min–max range of strain means38.4   –   98.8   U/L 29.9   –   103   U/L
Mean sample size per strain7.4   mice 7.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 524.3971 524.3971 2.3631 0.1252
strain 24 63652.8277 2652.2012 11.9518 < 0.0001
sex:strain 24 25243.7356 1051.8223 4.7399 < 0.0001
Residuals 339 75226.6798 221.9076


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 41.9 4.12   8 1.46 0.0984 37.0, 48.0 -1.49
129S1/SvImJ m 49.8 11.5   8 4.06 0.231 33.0, 66.0 -0.55
A/J f 78.2 21.1   6 8.62 0.27 59.0, 118.0 0.93
A/J m 32.4 11.2   8 3.95 0.345 10.0, 50.0 -1.54
AKR/J f 75.6 13.0   8 4.59 0.172 66.0, 105.0 0.75
BALB/cByJ f 81.8 10.3   8 3.62 0.125 65.0, 101.0 1.17
BALB/cByJ m 71.4 6.55   8 2.31 0.0917 59.0, 80.0 0.69
BTBR T+ Itpr3tf/J f 58.9 25.4   8 8.99 0.432 44.0, 121.0 -0.36
BTBR T+ Itpr3tf/J m 39.7 7.16   7 2.71 0.18 33.0, 53.0 -1.12
BUB/BnJ f 57.4 7.15   8 2.53 0.125 43.0, 64.0 -0.46
BUB/BnJ m 73.1 20.4   8 7.2 0.279 43.0, 108.0 0.79
C3H/HeJ f 69.9 6.27   8 2.22 0.0897 60.0, 77.0 0.37
C3H/HeJ m 60.8 8.25   16 2.06 0.136 48.0, 73.0 0.08
C57BL/10J f 59.6 10.2   8 3.61 0.171 46.0, 79.0 -0.31
C57BL/10J m 43.4 8.7   8 3.08 0.201 33.0, 59.0 -0.91
C57BL/6J f 98.8 20.3   4 10.2 0.206 85.0, 128.0 2.3
C57BL/6J m 92.0 19.7   4 9.85 0.214 77.0, 121.0 1.87
C57BLKS/J f 74.9 29.8   8 10.5 0.397 46.0, 141.0 0.71
C57BLKS/J m 47.8 7.5   8 2.65 0.157 33.0, 60.0 -0.66
C57BR/cdJ f 60.1 9.42   8 3.33 0.157 45.0, 78.0 -0.28
C57BR/cdJ m 59.8 8.05   8 2.85 0.135 46.0, 71.0 0.02
CAST/EiJ f 50.2 37.3   5 16.7 0.742 22.0, 110.0 -0.94
CBA/J m 29.9 5.72   8 2.02 0.191 21.0, 38.0 -1.69
DBA/2J f 78.9 5.84   8 2.07 0.0741 70.0, 85.0 0.97
DBA/2J m 53.8 5.37   8 1.9 0.0998 45.0, 60.0 -0.32
FVB/NJ f 63.8 7.69   8 2.72 0.121 50.0, 76.0 -0.03
FVB/NJ m 72.5 12.2   8 4.31 0.168 50.0, 87.0 0.75
KK/HlJ f 80.9 7.62   8 2.7 0.0943 71.0, 89.0 1.11
LP/J f 63.8 14.2   4 7.12 0.223 44.0, 76.0 -0.03
LP/J m 52.0 6.72   8 2.38 0.129 41.0, 65.0 -0.42
MOLF/EiJ f 83.6 9.66   7 3.65 0.116 69.0, 97.0 1.29
MOLF/EiJ m 80.2 18.8   8 6.65 0.234 66.0, 116.0 1.19
MRL/MpJ m 71.8 9.92   8 3.51 0.138 58.0, 90.0 0.71
NOD.B10Sn-H2b/J f 84.9 22.8   8 8.05 0.268 45.0, 122.0 1.37
NOD.B10Sn-H2b/J m 103.0 24.8   7 9.36 0.24 80.0, 152.0 2.5
NON/ShiLtJ f 46.2 9.77   8 3.45 0.211 27.0, 56.0 -1.21
NON/ShiLtJ m 69.4 16.1   8 5.69 0.232 41.0, 92.0 0.57
NZO/HlLtJ f 44.9 7.83   8 2.77 0.174 32.0, 59.0 -1.29
NZO/HlLtJ m 52.7 10.7   7 4.05 0.203 39.0, 73.0 -0.38
NZW/LacJ f 58.6 9.38   8 3.32 0.16 46.0, 73.0 -0.38
NZW/LacJ m 73.5 6.99   8 2.47 0.0951 63.0, 84.0 0.81
P/J f 65.4 9.65   8 3.41 0.148 50.0, 78.0 0.07
PL/J f 62.6 13.8   7 5.2 0.22 41.0, 76.0 -0.11
PL/J m 63.3 11.5   14 3.08 0.182 47.0, 82.0 0.23
PWD/PhJ f 58.0 12.2   8 4.3 0.21 45.0, 80.0 -0.42
PWD/PhJ m 38.2 6.46   6 2.64 0.169 28.0, 46.0 -1.21
RIIIS/J f 52.8 6.18   6 2.52 0.117 46.0, 64.0 -0.77
RIIIS/J m 57.2 11.6   8 4.1 0.202 40.0, 80.0 -0.12
SJL/J f 69.0 8.94   8 3.16 0.13 53.0, 81.0 0.31
SJL/J m 49.3 9.69   6 3.96 0.196 39.0, 66.0 -0.58
SM/J f 38.4 6.61   15 1.71 0.172 28.0, 55.0 -1.73
SM/J m 51.4 60.9   7 23.0 1.18 19.0, 189.0 -0.46
SWR/J f 65.9 7.4   8 2.61 0.112 54.0, 79.0 0.11
SWR/J m 70.4 15.6   7 5.88 0.221 42.0, 82.0 0.63
WSB/EiJ f 39.2 12.0   5 5.37 0.306 29.0, 60.0 -1.67
WSB/EiJ m 44.0 4.29   6 1.75 0.0975 38.0, 50.0 -0.88


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 41.875 5.2667 52.2346 31.5154
129S1/SvImJ m 49.75 5.2667 60.1096 39.3904
A/J f 78.1667 6.0815 90.1289 66.2044
A/J m 32.375 5.2667 42.7346 22.0154
BALB/cByJ f 81.75 5.2667 92.1096 71.3904
BALB/cByJ m 71.375 5.2667 81.7346 61.0154
BTBR T+ Itpr3tf/J f 58.875 5.2667 69.2346 48.5154
BTBR T+ Itpr3tf/J m 39.7143 5.6304 50.7892 28.6394
BUB/BnJ f 57.375 5.2667 67.7346 47.0154
BUB/BnJ m 73.125 5.2667 83.4846 62.7654
C3H/HeJ f 69.875 5.2667 80.2346 59.5154
C3H/HeJ m 60.75 3.7241 68.0753 53.4247
C57BL/10J f 59.625 5.2667 69.9846 49.2654
C57BL/10J m 43.375 5.2667 53.7346 33.0154
C57BL/6J f 98.75 7.4483 113.4007 84.0993
C57BL/6J m 92.0 7.4483 106.6507 77.3493
C57BLKS/J f 74.875 5.2667 85.2346 64.5154
C57BLKS/J m 47.75 5.2667 58.1096 37.3904
C57BR/cdJ f 60.125 5.2667 70.4846 49.7654
C57BR/cdJ m 59.75 5.2667 70.1096 49.3904
DBA/2J f 78.875 5.2667 89.2346 68.5154
DBA/2J m 53.75 5.2667 64.1096 43.3904
FVB/NJ f 63.75 5.2667 74.1096 53.3904
FVB/NJ m 72.5 5.2667 82.8596 62.1404
LP/J f 63.75 7.4483 78.4007 49.0993
LP/J m 52.0 5.2667 62.3596 41.6404
MOLF/EiJ f 83.5714 5.6304 94.6463 72.4966
MOLF/EiJ m 80.25 5.2667 90.6096 69.8904
NOD.B10Sn-H2b/J f 84.875 5.2667 95.2346 74.5154
NOD.B10Sn-H2b/J m 103.0 5.6304 114.0749 91.9251
NON/ShiLtJ f 46.25 5.2667 56.6096 35.8904
NON/ShiLtJ m 69.375 5.2667 79.7346 59.0154
NZO/HlLtJ f 44.875 5.2667 55.2346 34.5154
NZO/HlLtJ m 52.7143 5.6304 63.7892 41.6394
NZW/LacJ f 58.625 5.2667 68.9846 48.2654
NZW/LacJ m 73.5 5.2667 83.8596 63.1404
PL/J f 62.5714 5.6304 73.6463 51.4966
PL/J m 63.2857 3.9813 71.1168 55.4546
PWD/PhJ f 58.0 5.2667 68.3596 47.6404
PWD/PhJ m 38.1667 6.0815 50.1289 26.2044
RIIIS/J f 52.8333 6.0815 64.7956 40.8711
RIIIS/J m 57.25 5.2667 67.6096 46.8904
SJL/J f 69.0 5.2667 79.3596 58.6404
SJL/J m 49.3333 6.0815 61.2956 37.3711
SM/J f 38.4 3.8463 45.9656 30.8344
SM/J m 51.4286 5.6304 62.5034 40.3537
SWR/J f 65.875 5.2667 76.2346 55.5154
SWR/J m 70.4286 5.6304 81.5034 59.3537
WSB/EiJ f 39.2 6.6619 52.304 26.096
WSB/EiJ m 44.0 6.0815 55.9622 32.0378


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 45.8125 3.7241 53.1378 38.4872
A/J both 55.2708 4.0225 63.1831 47.3586
BALB/cByJ both 76.5625 3.7241 83.8878 69.2372
BTBR T+ Itpr3tf/J both 49.2946 3.8549 56.8771 41.7122
BUB/BnJ both 65.25 3.7241 72.5753 57.9247
C3H/HeJ both 65.3125 3.2252 71.6564 58.9686
C57BL/10J both 51.5 3.7241 58.8253 44.1747
C57BL/6J both 95.375 5.2667 105.7346 85.0154
C57BLKS/J both 61.3125 3.7241 68.6378 53.9872
C57BR/cdJ both 59.9375 3.7241 67.2628 52.6122
DBA/2J both 66.3125 3.7241 73.6378 58.9872
FVB/NJ both 68.125 3.7241 75.4503 60.7997
LP/J both 57.875 4.5611 66.8467 48.9033
MOLF/EiJ both 81.9107 3.8549 89.4932 74.3283
NOD.B10Sn-H2b/J both 93.9375 3.8549 101.5199 86.3551
NON/ShiLtJ both 57.8125 3.7241 65.1378 50.4872
NZO/HlLtJ both 48.7946 3.8549 56.3771 41.2122
NZW/LacJ both 66.0625 3.7241 73.3878 58.7372
PL/J both 62.9286 3.4479 69.7105 56.1466
PWD/PhJ both 48.0833 4.0225 55.9956 40.1711
RIIIS/J both 55.0417 4.0225 62.9539 47.1294
SJL/J both 59.1667 4.0225 67.0789 51.2544
SM/J both 44.9143 3.4094 51.6204 38.2081
SWR/J both 68.1518 3.8549 75.7342 60.5693
WSB/EiJ both 41.6 4.5102 50.4714 32.7286




  GWAS USING LINEAR MIXED MODELS