Project measure / variable:   Petkova1   CD4_effector_M18

ID, description, units MPD:24248   CD4_effector_M18   CD4 T cells, effector, as percentage of total CD4 T cells   [%]  at age 18mo  
Data set, strains Petkova1   inbred   30 strains     sex: both     age: 78wks
Procedure immune cell quantification
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  STRAIN COMPARISON PLOT
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Petkova1 - CD4 T cells, effector, as percentage of total CD4 T cells at age 18mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains25 strains
Mean of the strain means26.7   % 32.9   %
Median of the strain means23.5   % 27.3   %
SD of the strain means± 14.9 ± 20.8
Coefficient of variation (CV)0.559 0.633
Min–max range of strain means8.72   –   81.3   % 6.28   –   82.8   %
Mean sample size per strain7.3   mice 6.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1686.659 1686.659 8.4723 0.0039
strain 22 93115.5762 4232.5262 21.2606 < 0.0001
sex:strain 22 19312.951 877.8614 4.4096 < 0.0001
Residuals 278 55343.89 199.0787


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 20.9 3.92   7 1.48 0.187 14.7, 24.4 -0.39
129S1/SvImJ m 28.8 6.34   8 2.24 0.22 20.0, 37.4 -0.2
A/J f 17.5 6.68   8 2.36 0.383 9.61, 26.8 -0.62
BALB/cByJ f 39.8 8.08   8 2.86 0.203 29.0, 53.6 0.88
BALB/cByJ m 67.6 17.8   6 7.26 0.263 32.2, 80.3 1.66
BTBR T+ Itpr3tf/J f 8.72 2.93   8 1.04 0.336 4.02, 13.5 -1.21
BTBR T+ Itpr3tf/J m 10.8 2.46   5 1.1 0.228 7.73, 13.3 -1.06
BUB/BnJ f 10.2 5.47   8 1.93 0.537 4.49, 19.1 -1.11
BUB/BnJ m 19.4 2.57   6 1.05 0.133 16.4, 22.8 -0.65
C3H/HeJ f 22.4 6.25   8 2.21 0.279 16.2, 32.4 -0.29
C3H/HeJ m 17.5 3.77   8 1.33 0.216 12.4, 25.2 -0.74
C57BL/10J f 29.4 7.8   7 2.95 0.265 20.9, 45.1 0.18
C57BL/10J m 42.9 0.0   1   0.0 0.0 42.9, 42.9 0.48
C57BL/6J f 29.3 6.55   8 2.32 0.224 21.4, 38.5 0.17
C57BL/6J m 27.3 3.52   7 1.33 0.129 24.5, 33.3 -0.27
C57BLKS/J f 32.5 9.8   7 3.71 0.302 17.3, 44.7 0.39
C57BR/cdJ f 55.3 6.66   8 2.36 0.12 44.3, 67.9 1.92
C57BR/cdJ m 55.3 7.29   8 2.58 0.132 45.3, 66.0 1.07
C57L/J f 29.1 11.1   8 3.92 0.381 16.6, 50.9 0.16
C57L/J m 35.4 8.29   6 3.38 0.234 20.2, 41.9 0.12
CBA/J f 19.3 11.5   8 4.08 0.6 8.69, 45.0 -0.5
CBA/J m 17.8 8.1   6 3.31 0.456 10.2, 32.6 -0.73
DBA/2J f 23.5 6.08   7 2.3 0.259 17.5, 32.0 -0.21
DBA/2J m 15.2 5.05   8 1.78 0.333 8.96, 21.9 -0.85
FVB/NJ f 21.9 24.4   8 8.62 1.11 7.81, 81.0 -0.32
KK/HlJ f 39.8 16.5   7 6.25 0.415 19.7, 59.6 0.88
KK/HlJ m 33.8 8.79   7 3.32 0.26 23.2, 46.0 0.04
LP/J f 14.9 14.2   7 5.38 0.958 8.21, 46.7 -0.79
LP/J m 17.9 5.83   8 2.06 0.327 10.5, 26.5 -0.72
MOLF/EiJ f 81.3 7.36   9 2.45 0.0905 70.8, 90.8 3.66
MOLF/EiJ m 82.8 5.6   7 2.12 0.0677 75.0, 89.3 2.39
MRL/MpJ f 23.0 16.6   6 6.78 0.721 9.38, 53.5 -0.25
MRL/MpJ m 53.8 34.7   8 12.3 0.645 8.93, 85.2 1.0
NOD.B10Sn-H2b/J f 29.4 10.2   7 3.87 0.348 21.2, 50.5 0.18
NOD.B10Sn-H2b/J m 22.1 7.03   6 2.87 0.319 10.7, 28.7 -0.52
NON/ShiLtJ f 16.0 5.08   7 1.92 0.317 8.74, 23.7 -0.72
NON/ShiLtJ m 41.2 17.4   7 6.58 0.423 23.1, 78.4 0.4
NZO/HlLtJ f 21.1 8.53   3 4.93 0.404 15.3, 30.9 -0.38
NZW/LacJ f 23.7 30.5   8 10.8 1.29 5.83, 95.1 -0.2
NZW/LacJ m 14.9 5.48   7 2.07 0.367 8.11, 24.8 -0.87
P/J f 33.4 17.3   5 7.74 0.518 16.4, 62.5 0.45
P/J m 43.0 5.54   4 2.77 0.129 37.9, 50.5 0.48
PL/J f 23.7 11.6   4 5.78 0.488 12.1, 39.7 -0.2
PL/J m 75.3 5.98   5 2.68 0.0795 67.4, 80.9 2.03
PWD/PhJ f 35.2 30.8   8 10.9 0.875 7.05, 96.3 0.57
PWD/PhJ m 22.3 5.99   8 2.12 0.269 12.2, 32.3 -0.51
RIIIS/J m 12.3 4.42   8 1.56 0.36 8.44, 22.1 -0.99
SJL/J f 13.7 5.6   8 1.98 0.409 7.06, 22.6 -0.87
SJL/J m 41.9 20.8   7 7.87 0.497 18.7, 67.7 0.43
SM/J f 10.4 5.34   7 2.02 0.512 6.53, 21.3 -1.09
SWR/J f 37.5 40.7   7 15.4 1.08 9.54, 97.7 0.72
SWR/J m 17.8 10.4   6 4.24 0.583 9.94, 38.4 -0.73
WSB/EiJ f 11.6 19.9   8 7.04 1.71 2.77, 60.8 -1.01
WSB/EiJ m 6.28 1.22   7 0.459 0.194 4.83, 7.72 -1.28


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 20.9 5.3329 31.398 10.402
129S1/SvImJ m 28.775 4.9885 38.595 18.955
BALB/cByJ f 39.825 4.9885 49.645 30.005
BALB/cByJ m 67.6 5.7602 78.9391 56.2609
BTBR T+ Itpr3tf/J f 8.7187 4.9885 18.5387 0.0
BTBR T+ Itpr3tf/J m 10.77 6.31 23.1914 0.0
BUB/BnJ f 10.1962 4.9885 20.0162 0.3763
BUB/BnJ m 19.3667 5.7602 30.7058 8.0275
C3H/HeJ f 22.375 4.9885 32.195 12.555
C3H/HeJ m 17.475 4.9885 27.295 7.655
C57BL/6J f 29.275 4.9885 39.095 19.455
C57BL/6J m 27.3 5.3329 37.798 16.802
C57BR/cdJ f 55.3125 4.9885 65.1325 45.4925
C57BR/cdJ m 55.2625 4.9885 65.0825 45.4425
C57L/J f 29.1125 4.9885 38.9325 19.2925
C57L/J m 35.4167 5.7602 46.7558 24.0775
CBA/J f 19.2613 4.9885 29.0812 9.4413
CBA/J m 17.7833 5.7602 29.1225 6.4442
DBA/2J f 23.5143 5.3329 34.0123 13.0163
DBA/2J m 15.1525 4.9885 24.9725 5.3325
KK/HlJ f 39.8143 5.3329 50.3123 29.3163
KK/HlJ m 33.8 5.3329 44.298 23.302
LP/J f 14.86 5.3329 25.358 4.362
LP/J m 17.85 4.9885 27.67 8.03
MOLF/EiJ f 81.3222 4.7032 90.5806 72.0639
MOLF/EiJ m 82.7857 5.3329 93.2837 72.2877
MRL/MpJ f 23.03 5.7602 34.3691 11.6909
MRL/MpJ m 53.7662 4.9885 63.5862 43.9463
NOD.B10Sn-H2b/J f 29.4143 5.3329 39.9123 18.9163
NOD.B10Sn-H2b/J m 22.05 5.7602 33.3891 10.7109
NON/ShiLtJ f 15.9914 5.3329 26.4894 5.4934
NON/ShiLtJ m 41.2 5.3329 51.698 30.702
NZW/LacJ f 23.7312 4.9885 33.5512 13.9113
NZW/LacJ m 14.93 5.3329 25.428 4.432
P/J f 33.44 6.31 45.8614 21.0186
P/J m 42.95 7.0548 56.8375 29.0625
PL/J f 23.7 7.0548 37.5875 9.8125
PL/J m 75.3 6.31 87.7214 62.8786
PWD/PhJ f 35.1938 4.9885 45.0137 25.3738
PWD/PhJ m 22.2625 4.9885 32.0825 12.4425
SJL/J f 13.6875 4.9885 23.5075 3.8675
SJL/J m 41.9143 5.3329 52.4123 31.4163
SWR/J f 37.5486 5.3329 48.0466 27.0506
SWR/J m 17.79 5.7602 29.1291 6.4509
WSB/EiJ f 11.6487 4.9885 21.4687 1.8288
WSB/EiJ m 6.2757 5.3329 16.7737 0.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 24.8375 3.6512 32.025 17.65
BALB/cByJ both 53.7125 3.81 61.2126 46.2124
BTBR T+ Itpr3tf/J both 9.7444 4.0218 17.6615 1.8273
BUB/BnJ both 14.7815 3.81 22.2816 7.2813
C3H/HeJ both 19.925 3.5274 26.8688 12.9812
C57BL/6J both 28.2875 3.6512 35.475 21.1
C57BR/cdJ both 55.2875 3.5274 62.2313 48.3437
C57L/J both 32.2646 3.81 39.7647 24.7645
CBA/J both 18.5223 3.81 26.0224 11.0222
DBA/2J both 19.3334 3.6512 26.5209 12.1459
KK/HlJ both 36.8071 3.7709 44.2303 29.3839
LP/J both 16.355 3.6512 23.5425 9.1675
MOLF/EiJ both 82.054 3.5553 89.0526 75.0553
MRL/MpJ both 38.3981 3.81 45.8983 30.898
NOD.B10Sn-H2b/J both 25.7321 3.9249 33.4585 18.0058
NON/ShiLtJ both 28.5957 3.7709 36.0189 21.1725
NZW/LacJ both 19.3306 3.6512 26.5181 12.1431
P/J both 38.195 4.7325 47.511 28.879
PL/J both 49.5 4.7325 58.816 40.184
PWD/PhJ both 28.7281 3.5274 35.6719 21.7844
SJL/J both 27.8009 3.6512 34.9884 20.6134
SWR/J both 27.6693 3.9249 35.3956 19.943
WSB/EiJ both 8.9622 3.6512 16.1497 1.7747




  GWAS USING LINEAR MIXED MODELS