Project measure / variable:   Petkova1   CD4_effector_M06

ID, description, units MPD:24246   CD4_effector_M06   CD4 T cells, effector, as percentage of total CD4 T cells   [%]  at age 6mo  
Data set, strains Petkova1   inbred   32 strains     sex: both     age: 26wks
Procedure immune cell quantification
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Petkova1 - CD4 T cells, effector, as percentage of total CD4 T cells at age 6mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested32 strains31 strains
Mean of the strain means53.4   % 48.2   %
Median of the strain means53.7   % 46.5   %
SD of the strain means± 19.3 ± 20.0
Coefficient of variation (CV)0.361 0.416
Min–max range of strain means20.0   –   86.5   % 14.6   –   92.1   %
Mean sample size per strain8.0   mice 7.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1630.1625 1630.1625 16.8153 < 0.0001
strain 30 131788.8547 4392.9618 45.3139 < 0.0001
sex:strain 30 53081.761 1769.392 18.2515 < 0.0001
Residuals 435 42171.098 96.9451


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 52.8 12.5   8 4.41 0.236 33.7, 71.6 -0.03
129S1/SvImJ m 63.6 2.6   8 0.919 0.0409 59.9, 68.2 0.77
A/J f 69.2 4.28   8 1.51 0.0618 61.7, 73.6 0.82
A/J m 55.7 4.99   8 1.77 0.0896 49.6, 63.6 0.37
AKR/J f 54.2 15.0   8 5.31 0.277 31.1, 69.9 0.04
AKR/J m 34.2 10.5   8 3.72 0.307 20.4, 55.1 -0.7
BALB/cByJ f 73.9 6.36   8 2.25 0.0861 63.1, 84.0 1.06
BALB/cByJ m 38.2 32.4   8 11.5 0.847 10.0, 88.4 -0.5
BTBR T+ Itpr3tf/J f 55.2 6.83   8 2.42 0.124 41.9, 64.3 0.09
BTBR T+ Itpr3tf/J m 53.7 9.16   8 3.24 0.171 41.5, 64.0 0.27
BUB/BnJ f 76.8 7.22   8 2.55 0.0941 67.9, 89.3 1.21
BUB/BnJ m 69.9 2.04   8 0.72 0.0291 66.7, 72.4 1.08
C3H/HeJ f 22.7 4.77   8 1.69 0.21 17.8, 31.1 -1.59
C3H/HeJ m 29.6 10.9   8 3.85 0.367 16.2, 50.1 -0.93
C57BL/10J f 34.7 9.72   8 3.44 0.28 26.3, 51.1 -0.97
C57BL/10J m 33.7 5.62   8 1.99 0.167 26.8, 43.0 -0.72
C57BL/6J f 31.7 7.71   8 2.73 0.243 23.3, 43.6 -1.12
C57BL/6J m 30.7 4.87   8 1.72 0.159 24.7, 37.1 -0.87
C57BLKS/J f 21.7 2.17   8 0.767 0.0999 18.9, 24.4 -1.64
C57BLKS/J m 25.3 2.48   8 0.878 0.098 22.7, 30.4 -1.14
C57BR/cdJ f 67.9 6.47   8 2.29 0.0954 58.8, 78.2 0.75
C57BR/cdJ m 46.5 4.21   8 1.49 0.0905 41.7, 51.4 -0.09
C57L/J f 49.8 5.46   8 1.93 0.11 40.0, 58.4 -0.19
C57L/J m 38.8 9.39   8 3.32 0.242 25.4, 56.8 -0.47
CAST/EiJ f 67.1 19.1   6 7.8 0.285 44.8, 86.4 0.71
CBA/J f 20.0 5.93   8 2.1 0.297 14.2, 32.4 -1.73
CBA/J m 50.3 5.08   8 1.8 0.101 41.6, 55.4 0.1
DBA/2J f 50.4 5.91   8 2.09 0.117 40.4, 58.6 -0.16
DBA/2J m 56.6 9.29   8 3.29 0.164 39.9, 66.9 0.42
FVB/NJ f 54.3 6.02   8 2.13 0.111 45.9, 63.7 0.05
FVB/NJ m 39.8 4.77   8 1.69 0.12 32.2, 46.9 -0.42
KK/HlJ f 49.5 14.0   8 4.95 0.283 24.9, 64.7 -0.2
KK/HlJ m 71.8 5.01   8 1.77 0.0697 65.6, 78.9 1.18
LP/J f 53.5 20.9   8 7.39 0.391 31.4, 78.5 0.01
LP/J m 52.1 22.4   8 7.92 0.431 18.8, 80.6 0.19
MOLF/EiJ f 84.9 2.47   7 0.933 0.0291 81.2, 88.7 1.63
MOLF/EiJ m 86.1 2.65   8 0.937 0.0308 82.4, 89.0 1.89
MRL/MpJ f 72.0 8.25   8 2.92 0.115 59.3, 81.4 0.96
MRL/MpJ m 73.6 2.55   8 0.901 0.0346 70.7, 79.3 1.27
NOD.B10Sn-H2b/J f 35.4 12.5   9 4.17 0.353 16.3, 49.9 -0.93
NOD.B10Sn-H2b/J m 37.4 8.24   7 3.11 0.22 23.1, 48.6 -0.54
NON/ShiLtJ f 73.5 6.93   8 2.45 0.0944 62.2, 85.1 1.04
NON/ShiLtJ m 30.9 5.89   8 2.08 0.191 21.7, 38.6 -0.86
NZO/HlLtJ f 49.5 7.27   8 2.57 0.147 39.2, 63.2 -0.2
NZO/HlLtJ m 56.0 6.58   8 2.33 0.118 49.2, 66.3 0.39
NZW/LacJ f 50.2 11.7   8 4.15 0.234 34.5, 70.9 -0.17
NZW/LacJ m 68.5 4.43   8 1.57 0.0647 62.8, 74.3 1.01
P/J f 72.8 4.02   8 1.42 0.0553 66.9, 78.3 1.01
P/J m 15.2 4.51   8 1.6 0.297 9.74, 24.5 -1.65
PL/J f 26.5 5.85   7 2.21 0.221 19.0, 33.5 -1.39
PL/J m 35.0 8.1   7 3.06 0.231 20.8, 45.6 -0.66
PWD/PhJ f 86.5 21.3   8 7.52 0.246 34.0, 96.0 1.72
PWD/PhJ m 92.1 1.74   8 0.614 0.0189 89.2, 93.7 2.19
RIIIS/J f 58.2 8.48   8 3.0 0.146 48.3, 72.7 0.25
RIIIS/J m 78.4 5.27   8 1.86 0.0673 71.0, 84.5 1.51
SJL/J f 78.1 5.76   8 2.04 0.0738 68.6, 84.8 1.28
SJL/J m 14.6 7.99   6 3.26 0.547 8.58, 29.6 -1.68
SM/J f 36.0 12.1   16 3.03 0.337 23.3, 62.6 -0.9
SM/J m 29.2 5.24   8 1.85 0.179 21.5, 37.0 -0.95
SWR/J f 53.9 13.2   8 4.65 0.244 32.9, 69.7 0.03
SWR/J m 52.4 5.29   8 1.87 0.101 45.5, 61.4 0.21
WSB/EiJ f 25.7 12.1   8 4.27 0.469 10.4, 37.6 -1.44
WSB/EiJ m 34.7 14.9   6 6.1 0.43 23.0, 63.5 -0.67


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 52.7875 3.4811 59.6294 45.9456
129S1/SvImJ m 63.55 3.4811 70.3919 56.7081
A/J f 69.2125 3.4811 76.0544 62.3706
A/J m 55.7375 3.4811 62.5794 48.8956
AKR/J f 54.225 3.4811 61.0669 47.3831
AKR/J m 34.25 3.4811 41.0919 27.4081
BALB/cByJ f 73.9125 3.4811 80.7544 67.0706
BALB/cByJ m 38.25 3.4811 45.0919 31.4081
BTBR T+ Itpr3tf/J f 55.175 3.4811 62.0169 48.3331
BTBR T+ Itpr3tf/J m 53.7 3.4811 60.5419 46.8581
BUB/BnJ f 76.7625 3.4811 83.6044 69.9206
BUB/BnJ m 69.925 3.4811 76.7669 63.0831
C3H/HeJ f 22.7125 3.4811 29.5544 15.8706
C3H/HeJ m 29.65 3.4811 36.4919 22.8081
C57BL/10J f 34.7375 3.4811 41.5794 27.8956
C57BL/10J m 33.7 3.4811 40.5419 26.8581
C57BL/6J f 31.675 3.4811 38.5169 24.8331
C57BL/6J m 30.6625 3.4811 37.5044 23.8206
C57BLKS/J f 21.7125 3.4811 28.5544 14.8706
C57BLKS/J m 25.325 3.4811 32.1669 18.4831
C57BR/cdJ f 67.8875 3.4811 74.7294 61.0456
C57BR/cdJ m 46.525 3.4811 53.3669 39.6831
C57L/J f 49.825 3.4811 56.6669 42.9831
C57L/J m 38.8 3.4811 45.6419 31.9581
CBA/J f 19.95 3.4811 26.7919 13.1081
CBA/J m 50.275 3.4811 57.1169 43.4331
DBA/2J f 50.425 3.4811 57.2669 43.5831
DBA/2J m 56.6375 3.4811 63.4794 49.7956
FVB/NJ f 54.325 3.4811 61.1669 47.4831
FVB/NJ m 39.7875 3.4811 46.6294 32.9456
KK/HlJ f 49.5 3.4811 56.3419 42.6581
KK/HlJ m 71.825 3.4811 78.6669 64.9831
LP/J f 53.4625 3.4811 60.3044 46.6206
LP/J m 52.05 3.4811 58.8919 45.2081
MOLF/EiJ f 84.9429 3.7215 92.2571 77.6286
MOLF/EiJ m 86.0875 3.4811 92.9294 79.2456
MRL/MpJ f 72.0125 3.4811 78.8544 65.1706
MRL/MpJ m 73.6375 3.4811 80.4794 66.7956
NOD.B10Sn-H2b/J f 35.3556 3.282 41.8061 28.905
NOD.B10Sn-H2b/J m 37.4286 3.7215 44.7429 30.1143
NON/ShiLtJ f 73.4625 3.4811 80.3044 66.6206
NON/ShiLtJ m 30.8875 3.4811 37.7294 24.0456
NZO/HlLtJ f 49.5 3.4811 56.3419 42.6581
NZO/HlLtJ m 55.9625 3.4811 62.8044 49.1206
NZW/LacJ f 50.2 3.4811 57.0419 43.3581
NZW/LacJ m 68.5125 3.4811 75.3544 61.6706
P/J f 72.7875 3.4811 79.6294 65.9456
P/J m 15.2175 3.4811 22.0594 8.3756
PL/J f 26.5143 3.7215 33.8286 19.2
PL/J m 35.0143 3.7215 42.3286 27.7
PWD/PhJ f 86.5375 3.4811 93.3794 79.6956
PWD/PhJ m 92.075 3.4811 98.9169 85.2331
RIIIS/J f 58.225 3.4811 65.0669 51.3831
RIIIS/J m 78.4 3.4811 85.2419 71.5581
SJL/J f 78.0875 3.4811 84.9294 71.2456
SJL/J m 14.6133 4.0196 22.5137 6.713
SM/J f 36.025 2.4615 40.8629 31.1871
SM/J m 29.2 3.4811 36.0419 22.3581
SWR/J f 53.9125 3.4811 60.7544 47.0706
SWR/J m 52.4375 3.4811 59.2794 45.5956
WSB/EiJ f 25.725 3.4811 32.5669 18.8831
WSB/EiJ m 34.7 4.0196 42.6003 26.7997


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 58.1688 2.4615 63.0067 53.3308
A/J both 62.475 2.4615 67.3129 57.6371
AKR/J both 44.2375 2.4615 49.0754 39.3996
BALB/cByJ both 56.0813 2.4615 60.9192 51.2433
BTBR T+ Itpr3tf/J both 54.4375 2.4615 59.2754 49.5996
BUB/BnJ both 73.3437 2.4615 78.1817 68.5058
C3H/HeJ both 26.1813 2.4615 31.0192 21.3433
C57BL/10J both 34.2188 2.4615 39.0567 29.3808
C57BL/6J both 31.1687 2.4615 36.0067 26.3308
C57BLKS/J both 23.5187 2.4615 28.3567 18.6808
C57BR/cdJ both 57.2062 2.4615 62.0442 52.3683
C57L/J both 44.3125 2.4615 49.1504 39.4746
CBA/J both 35.1125 2.4615 39.9504 30.2746
DBA/2J both 53.5312 2.4615 58.3692 48.6933
FVB/NJ both 47.0562 2.4615 51.8942 42.2183
KK/HlJ both 60.6625 2.4615 65.5004 55.8246
LP/J both 52.7562 2.4615 57.5942 47.9183
MOLF/EiJ both 85.5152 2.5479 90.5229 80.5074
MRL/MpJ both 72.825 2.4615 77.6629 67.9871
NOD.B10Sn-H2b/J both 36.3921 2.481 41.2683 31.5159
NON/ShiLtJ both 52.175 2.4615 57.0129 47.3371
NZO/HlLtJ both 52.7312 2.4615 57.5692 47.8933
NZW/LacJ both 59.3563 2.4615 64.1942 54.5183
P/J both 44.0025 2.4615 48.8404 39.1646
PL/J both 30.7643 2.6315 35.9363 25.5923
PWD/PhJ both 89.3062 2.4615 94.1442 84.4683
RIIIS/J both 68.3125 2.4615 73.1504 63.4746
SJL/J both 46.3504 2.6587 51.576 41.1248
SM/J both 32.6125 2.1317 36.8023 28.4227
SWR/J both 53.175 2.4615 58.0129 48.3371
WSB/EiJ both 30.2125 2.6587 35.4381 24.9869




  GWAS USING LINEAR MIXED MODELS