Project measure / variable:   Petkova1   CD4_mem_central_M24

ID, description, units MPD:24240   CD4_mem_central_M24   CD4 T cells, central memory, as percentage of total CD4 T cells   [%]  at age 24mo  
Data set, strains Petkova1   inbred   12 strains     sex: both     age: 104wks
Procedure immune cell quantification
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  STRAIN COMPARISON PLOT
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Petkova1 - CD4 T cells, central memory, as percentage of total CD4 T cells at age 24mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested11 strains11 strains
Mean of the strain means8.68   % 8.76   %
Median of the strain means8.42   % 8.38   %
SD of the strain means± 1.59 ± 1.37
Coefficient of variation (CV)0.183 0.157
Min–max range of strain means6.32   –   11.6   % 6.76   –   10.5   %
Mean sample size per strain7.0   mice 7.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.8228 0.8228 0.0827 0.7742
strain 9 283.7914 31.5324 3.168 0.0018
sex:strain 9 45.1929 5.0214 0.5045 0.8689
Residuals 121 1204.3604 9.9534


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 8.71 1.69   6 0.688 0.194 6.9, 11.9 0.02
129S1/SvImJ m 9.71 2.38   7 0.899 0.245 5.85, 12.6 0.69
BALB/cByJ f 8.22 6.88   7 2.6 0.837 -0.29
C3H/HeJ m 9.37 2.28   8 0.806 0.243 6.96, 12.6 0.44
C57BL/10J f 7.1 2.45   8 0.867 0.346 3.13, 10.5 -0.99
C57BL/10J m 8.11 1.75   6 0.715 0.216 6.37, 11.2 -0.47
C57BL/6J f 8.81 1.61   8 0.571 0.183 5.6, 9.98 0.08
C57BL/6J m 10.4 4.08   8 1.44 0.394 3.81, 16.5 1.19
C57BLKS/J f 7.67 1.17   6 0.476 0.152 6.08, 8.95 -0.63
C57BLKS/J m 8.35 2.85   7 1.08 0.341 4.72, 12.3 -0.3
C57BR/cdJ f 6.32 2.31   7 0.872 0.365 3.52, 10.4 -1.48
C57BR/cdJ m 6.76 2.47   9 0.823 0.365 2.42, 10.6 -1.46
LP/J f 11.3 6.58   8 2.33 0.581 1.92, 22.7 1.65
LP/J m 10.3 4.68   6 1.91 0.455 5.28, 19.2 1.12
NON/ShiLtJ f 11.6 3.29   8 1.16 0.284 7.31, 16.2 1.84
NON/ShiLtJ m 10.5 3.02   7 1.14 0.287 6.32, 15.4 1.27
NZW/LacJ f 8.42 3.37   6 1.38 0.4 3.96, 13.0 -0.16
NZW/LacJ m 8.38 3.69   7 1.39 0.44 4.32, 15.2 -0.28
PWD/PhJ f 9.17 2.9   7 1.09 0.316 3.96, 12.5 0.31
PWD/PhJ m 6.94 1.81   7 0.685 0.261 4.91, 9.3 -1.33
WSB/EiJ f 8.11 3.12   6 1.27 0.384 4.64, 12.4 -0.36
WSB/EiJ m 7.55 2.14   7 0.808 0.283 3.85, 10.8 -0.88


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 8.7083 1.288 11.2582 6.1584
129S1/SvImJ m 9.7143 1.1924 12.075 7.3535
C57BL/10J f 7.0962 1.1154 9.3045 4.888
C57BL/10J m 8.1133 1.288 10.6632 5.5634
C57BL/6J f 8.805 1.1154 11.0133 6.5967
C57BL/6J m 10.3675 1.1154 12.5758 8.1592
C57BLKS/J f 7.6667 1.288 10.2166 5.1168
C57BLKS/J m 8.3543 1.1924 10.715 5.9935
C57BR/cdJ f 6.3243 1.1924 8.685 3.9635
C57BR/cdJ m 6.7578 1.0516 8.8398 4.6758
LP/J f 11.3325 1.1154 13.5408 9.1242
LP/J m 10.2983 1.288 12.8482 7.7484
NON/ShiLtJ f 11.59 1.1154 13.7983 9.3817
NON/ShiLtJ m 10.5357 1.1924 12.8965 8.175
NZW/LacJ f 8.4233 1.288 10.9732 5.8734
NZW/LacJ m 8.3771 1.1924 10.7379 6.0164
PWD/PhJ f 9.1729 1.1924 11.5336 6.8121
PWD/PhJ m 6.9371 1.1924 9.2979 4.5764
WSB/EiJ f 8.1117 1.288 10.6616 5.5618
WSB/EiJ m 7.5471 1.1924 9.9079 5.1864


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 9.2113 0.8776 10.9488 7.4738
C57BL/10J both 7.6048 0.8519 9.2914 5.9182
C57BL/6J both 9.5863 0.7887 11.1477 8.0248
C57BLKS/J both 8.0105 0.8776 9.7479 6.273
C57BR/cdJ both 6.541 0.795 8.1149 4.9672
LP/J both 10.8154 0.8519 12.502 9.1288
NON/ShiLtJ both 11.0629 0.8164 12.6792 9.4466
NZW/LacJ both 8.4002 0.8776 10.1377 6.6628
PWD/PhJ both 8.055 0.8432 9.7243 6.3857
WSB/EiJ both 7.8294 0.8776 9.5669 6.0919




  GWAS USING LINEAR MIXED MODELS