Project measure / variable:   Petkova1   CD4_mem_central_M12

ID, description, units MPD:24238   CD4_mem_central_M12   CD4 T cells, central memory, as percentage of total CD4 T cells   [%]  at age 12mo  
Data set, strains Petkova1   inbred   31 strains     sex: both     age: 52wks
Procedure immune cell quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Petkova1 - CD4 T cells, central memory, as percentage of total CD4 T cells at age 12mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested30 strains30 strains
Mean of the strain means6.71   % 6.04   %
Median of the strain means6.35   % 5.54   %
SD of the strain means± 3.37 ± 2.39
Coefficient of variation (CV)0.503 0.395
Min–max range of strain means0.0809   –   15.7   % 0.0763   –   10.9   %
Mean sample size per strain7.6   mice 7.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 49.2543 49.2543 13.807 0.0002
strain 28 3117.0923 111.3247 31.2066 < 0.0001
sex:strain 28 647.9344 23.1405 6.4868 < 0.0001
Residuals 389 1387.6959 3.5673


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 7.53 1.58   8 0.559 0.21 5.14, 9.46 0.24
129S1/SvImJ m 2.43 1.21   8 0.429 0.499 1.31, 4.43 -1.51
A/J f 6.8 1.17   8 0.412 0.172 5.12, 8.97 0.03
A/J m 7.93 1.36   8 0.482 0.172 4.88, 9.44 0.79
AKR/J m 7.91 2.08   5 0.931 0.263 6.57, 11.5 0.79
BALB/cByJ f 8.32 1.42   8 0.501 0.17 6.06, 9.89 0.48
BALB/cByJ m 3.04 0.836   8 0.296 0.275 1.42, 3.85 -1.26
BTBR T+ Itpr3tf/J f 4.57 0.687   8 0.243 0.15 3.93, 6.04 -0.63
BTBR T+ Itpr3tf/J m 4.99 1.05   7 0.396 0.21 3.86, 6.76 -0.44
BUB/BnJ f 8.44 2.33   6 0.95 0.276 5.31, 11.2 0.51
BUB/BnJ m 6.7 2.35   9 0.785 0.351 3.02, 10.2 0.28
C3H/HeJ f 5.65 1.24   8 0.438 0.219 3.89, 7.14 -0.31
C3H/HeJ m 5.31 1.13   8 0.401 0.214 3.26, 7.04 -0.3
C57BL/10J f 8.01 2.11   8 0.747 0.264 4.48, 10.9 0.39
C57BL/10J m 10.5 2.38   7 0.899 0.226 8.28, 15.5 1.87
C57BL/6J f 6.72 1.26   8 0.445 0.187 4.99, 8.63 0.0
C57BL/6J m 6.76 3.29   8 1.16 0.486 3.92, 14.5 0.3
C57BLKS/J f 15.4 3.85   8 1.36 0.25 8.79, 21.5 2.58
C57BLKS/J m 8.81 0.981   8 0.347 0.111 7.35, 10.1 1.16
C57BR/cdJ f 4.14 1.02   8 0.361 0.247 2.11, 5.52 -0.76
C57BR/cdJ m 4.95 1.36   8 0.481 0.275 2.81, 6.28 -0.46
C57L/J f 6.23 2.52   7 0.953 0.405 3.68, 11.3 -0.14
C57L/J m 6.12 0.866   8 0.306 0.142 4.78, 7.46 0.04
CAST/EiJ f 9.74 1.47   3 0.847 0.151 8.13, 11.0 0.9
CBA/J f 6.46 1.93   8 0.683 0.299 2.9, 9.06 -0.07
CBA/J m 6.53 1.29   8 0.455 0.197 4.18, 8.18 0.21
DBA/2J f 6.85 1.07   6 0.438 0.157 5.61, 8.21 0.04
DBA/2J m 6.43 1.31   7 0.495 0.203 5.21, 8.87 0.17
FVB/NJ f 4.05 0.582   8 0.206 0.144 3.15, 4.62 -0.79
FVB/NJ m 3.7 1.01   8 0.355 0.272 2.37, 5.08 -0.98
KK/HlJ f 6.49 0.754   8 0.267 0.116 4.69, 7.1 -0.06
KK/HlJ m 5.72 1.07   8 0.379 0.187 4.17, 7.52 -0.13
LP/J f 12.4 4.79   7 1.81 0.385 6.31, 18.2 1.69
LP/J m 9.46 4.15   8 1.47 0.439 5.83, 16.8 1.44
MOLF/EiJ f 0.0809 0.0505   7 0.0191 0.624 0.021, 0.16 -1.97
MOLF/EiJ m 0.0763 0.0695   9 0.0232 0.91 -2.5
MRL/MpJ f 5.22 1.26   8 0.445 0.241 3.43, 7.4 -0.44
MRL/MpJ m 8.29 1.8   8 0.637 0.217 5.36, 10.9 0.95
NON/ShiLtJ f 9.28 2.13   8 0.755 0.23 6.41, 12.2 0.76
NON/ShiLtJ m 5.25 1.63   6 0.666 0.311 2.89, 7.51 -0.33
NZO/HlLtJ f 1.76 0.127   7 0.048 0.0723 1.57, 1.89 -1.47
NZO/HlLtJ m 3.59 1.26   7 0.478 0.352 1.52, 5.16 -1.03
NZW/LacJ f 4.21 0.78   8 0.276 0.185 2.69, 5.28 -0.74
NZW/LacJ m 5.29 1.82   8 0.642 0.344 3.47, 8.56 -0.31
P/J f 5.29 1.78   8 0.629 0.336 2.95, 7.82 -0.42
P/J m 5.15 1.74   7 0.658 0.338 2.76, 7.85 -0.37
PL/J f 7.52 2.18   7 0.823 0.289 5.12, 11.1 0.24
PL/J m 8.92 0.804   6 0.328 0.0901 7.85, 10.1 1.21
PWD/PhJ f 5.14 1.5   8 0.531 0.292 3.15, 7.95 -0.46
PWD/PhJ m 5.02 1.52   8 0.537 0.303 3.56, 7.52 -0.43
RIIIS/J f 4.43 0.892   8 0.315 0.201 3.54, 6.49 -0.68
RIIIS/J m 5.36 1.75   8 0.618 0.326 3.23, 8.96 -0.28
SJL/J f 15.7 5.34   8 1.89 0.339 4.49, 21.4 2.67
SJL/J m 10.9 2.78   9 0.926 0.254 7.09, 15.8 2.04
SM/J f 5.37 0.819   8 0.289 0.152 4.39, 6.54 -0.4
SM/J m 6.74 1.68   8 0.593 0.249 4.46, 8.87 0.3
SWR/J f 4.7 1.3   7 0.492 0.277 3.6, 6.59 -0.6
SWR/J m 4.93 0.981   7 0.371 0.199 3.18, 6.23 -0.46
WSB/EiJ f 4.69 0.586   8 0.207 0.125 3.94, 5.44 -0.6
WSB/EiJ m 4.26 1.01   8 0.357 0.237 2.99, 6.44 -0.74


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 7.5262 0.6678 8.8391 6.2134
129S1/SvImJ m 2.4312 0.6678 3.7441 1.1184
A/J f 6.7963 0.6678 8.1091 5.4834
A/J m 7.9338 0.6678 9.2466 6.6209
BALB/cByJ f 8.3213 0.6678 9.6341 7.0084
BALB/cByJ m 3.0387 0.6678 4.3516 1.7259
BTBR T+ Itpr3tf/J f 4.5675 0.6678 5.8804 3.2546
BTBR T+ Itpr3tf/J m 4.9929 0.7139 6.3964 3.5893
BUB/BnJ f 8.4417 0.7711 9.9577 6.9257
BUB/BnJ m 6.6989 0.6296 7.9367 5.4611
C3H/HeJ f 5.6488 0.6678 6.9616 4.3359
C3H/HeJ m 5.3075 0.6678 6.6204 3.9946
C57BL/10J f 8.0088 0.6678 9.3216 6.6959
C57BL/10J m 10.5186 0.7139 11.9221 9.115
C57BL/6J f 6.72 0.6678 8.0329 5.4071
C57BL/6J m 6.765 0.6678 8.0779 5.4521
C57BLKS/J f 15.3987 0.6678 16.7116 14.0859
C57BLKS/J m 8.81 0.6678 10.1229 7.4971
C57BR/cdJ f 4.14 0.6678 5.4529 2.8271
C57BR/cdJ m 4.9513 0.6678 6.2641 3.6384
C57L/J f 6.2286 0.7139 7.6321 4.825
C57L/J m 6.1163 0.6678 7.4291 4.8034
CBA/J f 6.4575 0.6678 7.7704 5.1446
CBA/J m 6.5275 0.6678 7.8404 5.2146
DBA/2J f 6.8517 0.7711 8.3677 5.3357
DBA/2J m 6.4343 0.7139 7.8378 5.0307
FVB/NJ f 4.0488 0.6678 5.3616 2.7359
FVB/NJ m 3.7012 0.6678 5.0141 2.3884
KK/HlJ f 6.4913 0.6678 7.8041 5.1784
KK/HlJ m 5.7238 0.6678 7.0366 4.4109
LP/J f 12.44 0.7139 13.8435 11.0365
LP/J m 9.4575 0.6678 10.7704 8.1446
MOLF/EiJ f 0.0809 0.7139 1.4844 0.0
MOLF/EiJ m 0.0763 0.6296 1.3141 0.0
MRL/MpJ f 5.22 0.6678 6.5329 3.9071
MRL/MpJ m 8.29 0.6678 9.6029 6.9771
NON/ShiLtJ f 9.2838 0.6678 10.5966 7.9709
NON/ShiLtJ m 5.2533 0.7711 6.7693 3.7373
NZO/HlLtJ f 1.7557 0.7139 3.1593 0.3522
NZO/HlLtJ m 3.5943 0.7139 4.9978 2.1907
NZW/LacJ f 4.21 0.6678 5.5229 2.8971
NZW/LacJ m 5.285 0.6678 6.5979 3.9721
P/J f 5.2938 0.6678 6.6066 3.9809
P/J m 5.1457 0.7139 6.5493 3.7422
PL/J f 7.52 0.7139 8.9235 6.1165
PL/J m 8.9217 0.7711 10.4377 7.4057
PWD/PhJ f 5.135 0.6678 6.4479 3.8221
PWD/PhJ m 5.0162 0.6678 6.3291 3.7034
RIIIS/J f 4.4337 0.6678 5.7466 3.1209
RIIIS/J m 5.3625 0.6678 6.6754 4.0496
SJL/J f 15.7488 0.6678 17.0616 14.4359
SJL/J m 10.9256 0.6296 12.1634 9.6877
SM/J f 5.37 0.6678 6.6829 4.0571
SM/J m 6.7438 0.6678 8.0566 5.4309
SWR/J f 4.7029 0.7139 6.1064 3.2993
SWR/J m 4.9286 0.7139 6.3321 3.525
WSB/EiJ f 4.6888 0.6678 6.0016 3.3759
WSB/EiJ m 4.2562 0.6678 5.5691 2.9434


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 4.9787 0.4722 5.9071 4.0504
A/J both 7.365 0.4722 8.2934 6.4366
BALB/cByJ both 5.68 0.4722 6.6084 4.7516
BTBR T+ Itpr3tf/J both 4.7802 0.4888 5.7411 3.8192
BUB/BnJ both 7.5703 0.4977 8.5488 6.5917
C3H/HeJ both 5.4781 0.4722 6.4065 4.5498
C57BL/10J both 9.2637 0.4888 10.2246 8.3027
C57BL/6J both 6.7425 0.4722 7.6709 5.8141
C57BLKS/J both 12.1044 0.4722 13.0327 11.176
C57BR/cdJ both 4.5456 0.4722 5.474 3.6173
C57L/J both 6.1724 0.4888 7.1333 5.2115
CBA/J both 6.4925 0.4722 7.4209 5.5641
DBA/2J both 6.643 0.5254 7.676 5.61
FVB/NJ both 3.875 0.4722 4.8034 2.9466
KK/HlJ both 6.1075 0.4722 7.0359 5.1791
LP/J both 10.9488 0.4888 11.9097 9.9878
MOLF/EiJ both 0.0786 0.4759 1.0143 0.0
MRL/MpJ both 6.755 0.4722 7.6834 5.8266
NON/ShiLtJ both 7.2685 0.51 8.2713 6.2658
NZO/HlLtJ both 2.675 0.5048 3.6675 1.6825
NZW/LacJ both 4.7475 0.4722 5.6759 3.8191
P/J both 5.2197 0.4888 6.1807 4.2588
PL/J both 8.2208 0.5254 9.2538 7.1879
PWD/PhJ both 5.0756 0.4722 6.004 4.1473
RIIIS/J both 4.8981 0.4722 5.8265 3.9698
SJL/J both 13.3372 0.4589 14.2394 12.435
SM/J both 6.0569 0.4722 6.9852 5.1285
SWR/J both 4.8157 0.5048 5.8082 3.8233
WSB/EiJ both 4.4725 0.4722 5.4009 3.5441




  GWAS USING LINEAR MIXED MODELS