Phenotype measure:   Petkova1   CD4_naive_M24

ID, description, units MPD:24236   CD4_naive_M24   CD4 T cells, naive, as percentage of total CD4 T cells   [%]  at age 24mo
Data set, strains Petkova1   inbred   12 strains     sex: both     age: 104wks
Procedure immune cell quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Petkova1 - CD4 T cells, naive, as percentage of total CD4 T cells at age 24mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested11 strains11 strains
Mean of the strain means28.0   % 40.0   %
Median of the strain means26.2   % 41.5   %
SD of the strain means± 16.0 ± 16.5
Coefficient of variation (CV)0.572 0.412
Min–max range of strain means6.75   –   50.8   % 13.0   –   59.0   %
Mean sample size per strain7.0   mice 7.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 4723.4875 4723.4875 28.5552 < 0.0001
strain 9 32705.0182 3633.8909 21.9682 < 0.0001
sex:strain 9 2205.1273 245.0141 1.4812 0.1623
Residuals 121 20015.3067 165.4158


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 42.9 19.6   6 8.0 0.457 11.5, 59.9 0.93
129S1/SvImJ m 41.5 3.18   7 1.2 0.0766 36.4, 45.2 0.09
BALB/cByJ f 20.1 8.46   7 3.2 0.421 7.49, 30.5 -0.49
C3H/HeJ m 53.2 14.5   8 5.12 0.272 32.3, 70.3 0.8
C57BL/10J f 8.99 5.56   8 1.96 0.618 3.57, 19.8 -1.19
C57BL/10J m 13.0 6.08   6 2.48 0.466 4.0, 22.4 -1.64
C57BL/6J f 6.75 1.78   8 0.628 0.263 5.06, 9.84 -1.33
C57BL/6J m 22.1 10.9   8 3.85 0.492 7.62, 34.4 -1.09
C57BLKS/J f 40.7 5.0   6 2.04 0.123 36.0, 46.2 0.79
C57BLKS/J m 52.2 4.42   7 1.67 0.0846 43.3, 56.4 0.74
C57BR/cdJ f 20.0 6.48   7 2.45 0.324 7.59, 27.7 -0.5
C57BR/cdJ m 33.8 16.4   9 5.46 0.485 6.28, 50.2 -0.38
LP/J f 36.5 18.2   8 6.44 0.499 12.0, 58.0 0.53
LP/J m 38.1 17.1   6 6.99 0.449 13.3, 58.2 -0.12
NON/ShiLtJ f 9.58 2.88   8 1.02 0.301 4.62, 13.8 -1.15
NON/ShiLtJ m 17.6 4.92   7 1.86 0.28 10.9, 27.0 -1.36
NZW/LacJ f 45.8 25.1   6 10.3 0.548 13.4, 71.3 1.11
NZW/LacJ m 54.8 21.9   7 8.29 0.4 25.4, 76.9 0.9
PWD/PhJ f 26.2 12.6   7 4.75 0.479 7.18, 39.8 -0.11
PWD/PhJ m 54.9 17.2   7 6.48 0.313 20.6, 76.2 0.9
WSB/EiJ f 50.8 13.8   6 5.63 0.272 38.0, 68.5 1.42
WSB/EiJ m 59.0 8.58   7 3.24 0.145 49.0, 72.7 1.15


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 42.9333 5.2506 53.3284 32.5383
129S1/SvImJ m 41.5286 4.8612 51.1525 31.9046
C57BL/10J f 8.995 4.5472 17.9974 0.0
C57BL/10J m 13.0333 5.2506 23.4284 2.6383
C57BL/6J f 6.7475 4.5472 15.7499 0.0
C57BL/6J m 22.1338 4.5472 31.1361 13.1314
C57BLKS/J f 40.7 5.2506 51.095 30.305
C57BLKS/J m 52.2429 4.8612 61.8668 42.6189
C57BR/cdJ f 19.9843 4.8612 29.6082 10.3603
C57BR/cdJ m 33.7544 4.2871 42.242 25.2669
LP/J f 36.5 4.5472 45.5024 27.4976
LP/J m 38.15 5.2506 48.545 27.755
NON/ShiLtJ f 9.5763 4.5472 18.5786 0.5739
NON/ShiLtJ m 17.6 4.8612 27.2239 7.9761
NZW/LacJ f 45.8333 5.2506 56.2284 35.4383
NZW/LacJ m 54.8429 4.8612 64.4668 45.2189
PWD/PhJ f 26.2257 4.8612 35.8497 16.6018
PWD/PhJ m 54.8714 4.8612 64.4954 45.2475
WSB/EiJ f 50.7833 5.2506 61.1784 40.3883
WSB/EiJ m 59.0 4.8612 68.6239 49.3761


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 42.231 3.5777 49.314 35.1479
C57BL/10J both 11.0142 3.473 17.8898 4.1385
C57BL/6J both 14.4406 3.2154 20.8063 8.075
C57BLKS/J both 46.4714 3.5777 53.5545 39.3884
C57BR/cdJ both 26.8694 3.2408 33.2853 20.4534
LP/J both 37.325 3.473 44.2007 30.4493
NON/ShiLtJ both 13.5881 3.3282 20.1772 6.9991
NZW/LacJ both 50.3381 3.5777 57.4211 43.2551
PWD/PhJ both 40.5486 3.4374 47.3537 33.7434
WSB/EiJ both 54.8917 3.5777 61.9747 47.8086




  GWAS USING LINEAR MIXED MODELS