Phenotype measure:   Petkova1   CD4_naive_M18

ID, description, units MPD:24235   CD4_naive_M18   CD4 T cells, naive, as percentage of total CD4 T cells   [%]  at age 18mo
Data set, strains Petkova1   inbred   30 strains     sex: both     age: 78wks
Procedure immune cell quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Petkova1 - CD4 T cells, naive, as percentage of total CD4 T cells at age 18mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains25 strains
Mean of the strain means40.2   % 43.4   %
Median of the strain means39.0   % 42.3   %
SD of the strain means± 19.8 ± 22.4
Coefficient of variation (CV)0.492 0.516
Min–max range of strain means0.190   –   74.6   % 0.119   –   80.7   %
Mean sample size per strain7.3   mice 6.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2567.6477 2567.6477 12.2282 0.0005
strain 22 121305.2066 5513.873 26.2594 < 0.0001
sex:strain 22 13758.2608 625.3755 2.9783 < 0.0001
Residuals 278 58373.6417 209.9771


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 50.1 11.8   7 4.48 0.237 27.0, 60.7 0.5
129S1/SvImJ m 52.6 7.14   8 2.52 0.136 41.2, 61.6 0.41
A/J f 58.5 17.4   8 6.15 0.297 20.3, 73.7 0.93
BALB/cByJ f 33.0 14.6   8 5.16 0.443 5.36, 46.4 -0.36
BALB/cByJ m 17.3 14.8   6 6.03 0.853 7.17, 46.5 -1.17
BTBR T+ Itpr3tf/J f 64.7 12.0   8 4.25 0.186 36.3, 73.5 1.24
BTBR T+ Itpr3tf/J m 66.0 5.75   5 2.57 0.087 57.6, 71.2 1.01
BUB/BnJ f 53.6 15.5   8 5.47 0.289 25.3, 65.1 0.68
BUB/BnJ m 54.4 7.16   6 2.92 0.132 42.1, 63.1 0.49
C3H/HeJ f 50.1 9.8   8 3.47 0.196 39.3, 61.7 0.5
C3H/HeJ m 62.5 6.87   8 2.43 0.11 54.0, 70.2 0.85
C57BL/10J f 15.9 6.04   7 2.28 0.378 8.93, 25.3 -1.23
C57BL/10J m 16.4 0.0   1   0.0 0.0 16.4, 16.4 -1.21
C57BL/6J f 31.0 10.3   8 3.65 0.333 20.4, 46.9 -0.47
C57BL/6J m 37.6 15.9   7 6.03 0.424 11.7, 58.8 -0.26
C57BLKS/J f 50.0 6.99   7 2.64 0.14 37.9, 59.8 0.5
C57BR/cdJ f 21.7 8.98   8 3.17 0.414 7.13, 39.7 -0.94
C57BR/cdJ m 26.3 6.88   8 2.43 0.261 17.1, 35.3 -0.76
C57L/J f 25.4 11.6   8 4.1 0.457 7.62, 43.9 -0.75
C57L/J m 42.3 7.58   6 3.1 0.179 32.6, 52.8 -0.05
CBA/J f 53.1 15.6   8 5.51 0.294 28.7, 71.6 0.65
CBA/J m 68.0 8.22   6 3.36 0.121 54.5, 77.6 1.1
DBA/2J f 37.7 12.9   7 4.88 0.343 13.7, 53.1 -0.13
DBA/2J m 55.5 6.76   8 2.39 0.122 42.0, 63.2 0.54
FVB/NJ f 66.0 23.6   8 8.34 0.358 9.43, 80.0 1.3
KK/HlJ f 24.1 9.33   7 3.53 0.387 8.64, 35.9 -0.81
KK/HlJ m 33.7 4.88   7 1.84 0.145 25.4, 41.7 -0.43
LP/J f 62.4 18.9   7 7.15 0.303 32.7, 78.8 1.12
LP/J m 52.2 26.3   8 9.29 0.503 18.8, 78.6 0.39
MOLF/EiJ f 0.19 0.0686   9 0.0229 0.361 0.11, 0.31 -2.02
MOLF/EiJ m 0.119 0.0791   7 0.0299 0.664 0.03, 0.27 -1.93
MRL/MpJ f 34.6 22.9   6 9.35 0.663 9.49, 62.7 -0.28
MRL/MpJ m 31.2 31.3   8 11.1 1.0 4.07, 83.8 -0.54
NOD.B10Sn-H2b/J f 5.91 3.87   7 1.46 0.654 2.7, 14.1 -1.73
NOD.B10Sn-H2b/J m 33.3 10.9   6 4.46 0.328 18.8, 45.3 -0.45
NON/ShiLtJ f 13.3 5.01   7 1.89 0.378 7.13, 22.8 -1.36
NON/ShiLtJ m 24.3 10.0   7 3.79 0.413 12.2, 35.2 -0.85
NZO/HlLtJ f 28.5 22.7   3 13.1 0.798 6.36, 51.7 -0.59
NZW/LacJ f 64.6 28.1   8 9.92 0.434 1.3, 86.4 1.23
NZW/LacJ m 69.9 16.0   7 6.03 0.228 35.8, 83.8 1.19
P/J f 31.9 21.3   5 9.54 0.669 11.0, 59.8 -0.42
P/J m 21.1 6.78   4 3.39 0.321 11.9, 28.2 -1.0
PL/J f 50.0 7.52   4 3.76 0.15 41.4, 59.1 0.5
PL/J m 9.05 1.36   5 0.61 0.151 7.03, 10.7 -1.53
PWD/PhJ f 47.9 24.1   8 8.52 0.503 2.49, 70.3 0.39
PWD/PhJ m 63.8 6.09   8 2.15 0.0956 55.3, 74.1 0.91
RIIIS/J m 71.6 11.4   8 4.02 0.159 45.6, 81.0 1.26
SJL/J f 16.8 10.1   8 3.56 0.6 8.56, 32.9 -1.18
SJL/J m 27.8 16.6   7 6.28 0.599 13.0, 57.8 -0.7
SM/J f 61.3 7.58   7 2.87 0.124 51.3, 71.1 1.07
SWR/J f 39.0 28.0   7 10.6 0.718 2.07, 71.5 -0.06
SWR/J m 66.8 7.49   6 3.06 0.112 56.8, 78.2 1.05
WSB/EiJ f 74.6 21.7   8 7.68 0.291 21.6, 85.3 1.74
WSB/EiJ m 80.7 3.02   7 1.14 0.0374 77.0, 85.4 1.67


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 50.0714 5.4769 60.8529 39.2899
129S1/SvImJ m 52.55 5.1232 62.6352 42.4648
BALB/cByJ f 32.9575 5.1232 43.0427 22.8723
BALB/cByJ m 17.3133 5.9158 28.9587 5.668
BTBR T+ Itpr3tf/J f 64.7375 5.1232 74.8227 54.6523
BTBR T+ Itpr3tf/J m 66.04 6.4804 78.7969 53.2831
BUB/BnJ f 53.6375 5.1232 63.7227 43.5523
BUB/BnJ m 54.4333 5.9158 66.0787 42.788
C3H/HeJ f 50.0875 5.1232 60.1727 40.0023
C3H/HeJ m 62.525 5.1232 72.6102 52.4398
C57BL/6J f 31.0125 5.1232 41.0977 20.9273
C57BL/6J m 37.5857 5.4769 48.3672 26.8042
C57BR/cdJ f 21.7037 5.1232 31.7889 11.6186
C57BR/cdJ m 26.3375 5.1232 36.4227 16.2523
C57L/J f 25.3525 5.1232 35.4377 15.2673
C57L/J m 42.2833 5.9158 53.9287 30.638
CBA/J f 53.05 5.1232 63.1352 42.9648
CBA/J m 68.0333 5.9158 79.6787 56.388
DBA/2J f 37.6857 5.4769 48.4672 26.9042
DBA/2J m 55.4875 5.1232 65.5727 45.4023
KK/HlJ f 24.12 5.4769 34.9015 13.3385
KK/HlJ m 33.7143 5.4769 44.4958 22.9328
LP/J f 62.4143 5.4769 73.1958 51.6328
LP/J m 52.25 5.1232 62.3352 42.1648
MOLF/EiJ f 0.19 4.8302 9.6984 0.0
MOLF/EiJ m 0.1191 5.4769 10.9007 0.0
MRL/MpJ f 34.5517 5.9158 46.197 22.9063
MRL/MpJ m 31.2088 5.1232 41.2939 21.1236
NOD.B10Sn-H2b/J f 5.9129 5.4769 16.6944 0.0
NOD.B10Sn-H2b/J m 33.3 5.9158 44.9454 21.6546
NON/ShiLtJ f 13.2614 5.4769 24.0429 2.4799
NON/ShiLtJ m 24.3143 5.4769 35.0958 13.5328
NZW/LacJ f 64.6375 5.1232 74.7227 54.5523
NZW/LacJ m 69.9 5.4769 80.6815 59.1185
P/J f 31.86 6.4804 44.6169 19.1031
P/J m 21.125 7.2453 35.3876 6.8624
PL/J f 50.05 7.2453 64.3126 35.7874
PL/J m 9.052 6.4804 21.8089 0.0
PWD/PhJ f 47.9237 5.1232 58.0089 37.8386
PWD/PhJ m 63.75 5.1232 73.8352 53.6648
SJL/J f 16.7975 5.1232 26.8827 6.7123
SJL/J m 27.7571 5.4769 38.5387 16.9756
SWR/J f 39.04 5.4769 49.8215 28.2585
SWR/J m 66.7667 5.9158 78.412 55.1213
WSB/EiJ f 74.6375 5.1232 84.7227 64.5523
WSB/EiJ m 80.7143 5.4769 91.4958 69.9328


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 51.3107 3.7498 58.6923 43.9291
BALB/cByJ both 25.1354 3.9129 32.8381 17.4327
BTBR T+ Itpr3tf/J both 65.3888 4.1305 73.5197 57.2578
BUB/BnJ both 54.0354 3.9129 61.7381 46.3327
C3H/HeJ both 56.3062 3.6226 63.4376 49.1749
C57BL/6J both 34.2991 3.7498 41.6807 26.9175
C57BR/cdJ both 24.0206 3.6226 31.1519 16.8893
C57L/J both 33.8179 3.9129 41.5206 26.1152
CBA/J both 60.5417 3.9129 68.2444 52.839
DBA/2J both 46.5866 3.7498 53.9682 39.205
KK/HlJ both 28.9171 3.8728 36.5408 21.2935
LP/J both 57.3321 3.7498 64.7137 49.9505
MOLF/EiJ both 0.1546 3.6513 7.3422 0.0
MRL/MpJ both 32.8802 3.9129 40.5829 25.1775
NOD.B10Sn-H2b/J both 19.6064 4.0309 27.5414 11.6714
NON/ShiLtJ both 18.7879 3.8728 26.4115 11.1642
NZW/LacJ both 67.2688 3.7498 74.6504 59.8871
P/J both 26.4925 4.8603 36.0601 16.9249
PL/J both 29.551 4.8603 39.1186 19.9834
PWD/PhJ both 55.8369 3.6226 62.9682 48.7056
SJL/J both 22.2773 3.7498 29.6589 14.8957
SWR/J both 52.9033 4.0309 60.8383 44.9684
WSB/EiJ both 77.6759 3.7498 85.0575 70.2943




  GWAS USING LINEAR MIXED MODELS