Phenotype measure:   Petkova1   CD4_naive_M12

ID, description, units MPD:24234   CD4_naive_M12   CD4 T cells, naive, as percentage of total CD4 T cells   [%]  at age 12mo
Data set, strains Petkova1   inbred   31 strains     sex: both     age: 52wks
Procedure immune cell quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Petkova1 - CD4 T cells, naive, as percentage of total CD4 T cells at age 12mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested30 strains30 strains
Mean of the strain means49.2   % 52.8   %
Median of the strain means56.5   % 59.4   %
SD of the strain means± 24.7 ± 20.5
Coefficient of variation (CV)0.503 0.389
Min–max range of strain means0.0944   –   86.3   % 0.112   –   81.3   %
Mean sample size per strain7.6   mice 7.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1452.8399 1452.8399 15.1011 0.0001
strain 28 190674.0752 6809.7884 70.7822 < 0.0001
sex:strain 28 45729.0872 1633.1817 16.9756 < 0.0001
Residuals 389 37424.7543 96.2076


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 66.5 4.14   8 1.46 0.0622 57.8, 70.4 0.7
129S1/SvImJ m 2.83 1.45   8 0.514 0.513 1.06, 4.51 -2.44
A/J f 68.1 4.47   8 1.58 0.0656 61.5, 73.0 0.77
A/J m 65.0 5.55   8 1.96 0.0854 57.6, 71.9 0.6
AKR/J m 49.5 23.6   5 10.5 0.476 9.21, 70.0 -0.16
BALB/cByJ f 44.3 9.0   8 3.18 0.203 31.7, 55.5 -0.2
BALB/cByJ m 51.7 25.5   8 9.0 0.493 13.0, 74.6 -0.05
BTBR T+ Itpr3tf/J f 72.4 3.64   8 1.29 0.0503 67.5, 78.2 0.94
BTBR T+ Itpr3tf/J m 69.8 3.53   7 1.33 0.0505 65.3, 75.6 0.83
BUB/BnJ f 59.9 8.61   6 3.52 0.144 43.2, 67.8 0.43
BUB/BnJ m 64.5 10.1   9 3.36 0.156 40.4, 73.7 0.57
C3H/HeJ f 12.7 9.25   8 3.27 0.727 1.17, 27.8 -1.48
C3H/HeJ m 24.8 8.32   8 2.94 0.335 14.8, 36.4 -1.36
C57BL/10J f 8.45 4.35   8 1.54 0.515 1.79, 15.6 -1.65
C57BL/10J m 40.3 9.42   7 3.56 0.234 26.5, 54.8 -0.61
C57BL/6J f 6.13 2.07   8 0.733 0.338 3.23, 9.16 -1.74
C57BL/6J m 31.7 5.32   8 1.88 0.167 24.2, 41.5 -1.03
C57BLKS/J f 55.5 4.84   8 1.71 0.0873 48.8, 64.4 0.26
C57BLKS/J m 64.9 1.92   8 0.679 0.0296 62.1, 67.6 0.59
C57BR/cdJ f 26.4 9.68   8 3.42 0.367 7.72, 36.8 -0.92
C57BR/cdJ m 62.1 3.33   8 1.18 0.0536 57.8, 68.9 0.45
C57L/J f 30.0 11.2   7 4.22 0.373 17.0, 44.2 -0.78
C57L/J m 28.3 6.61   8 2.34 0.233 20.2, 40.7 -1.19
CAST/EiJ f 55.0 5.74   3 3.32 0.104 48.7, 59.9 0.24
CBA/J f 65.5 20.8   8 7.37 0.318 14.5, 77.3 0.66
CBA/J m 76.4 2.8   8 0.989 0.0366 71.4, 80.7 1.15
DBA/2J f 46.0 7.05   6 2.88 0.153 34.8, 54.5 -0.13
DBA/2J m 67.6 3.95   7 1.49 0.0584 61.4, 72.7 0.72
FVB/NJ f 78.4 3.24   8 1.15 0.0414 73.8, 82.5 1.18
FVB/NJ m 72.4 7.2   8 2.55 0.0995 56.1, 78.8 0.96
KK/HlJ f 50.0 8.41   8 2.97 0.168 32.1, 56.8 0.03
KK/HlJ m 43.0 8.92   8 3.15 0.207 28.6, 54.5 -0.48
LP/J f 60.4 23.7   7 8.94 0.391 26.1, 84.2 0.45
LP/J m 59.6 22.6   8 8.0 0.38 18.2, 80.2 0.33
MOLF/EiJ f 0.0944 0.0383   7 0.0145 0.406 0.021, 0.14 -1.99
MOLF/EiJ m 0.112 0.0927   9 0.0309 0.829 0.017, 0.31 -2.57
MRL/MpJ f 18.0 11.5   8 4.08 0.64 8.91, 37.5 -1.26
MRL/MpJ m 71.1 10.9   8 3.84 0.153 47.9, 84.0 0.89
NON/ShiLtJ f 21.1 9.74   8 3.44 0.461 7.18, 37.5 -1.14
NON/ShiLtJ m 32.0 8.6   6 3.51 0.269 21.9, 45.8 -1.01
NZO/HlLtJ f 32.9 6.63   7 2.51 0.201 18.9, 39.3 -0.66
NZO/HlLtJ m 45.6 15.9   7 6.0 0.348 15.7, 63.9 -0.35
NZW/LacJ f 86.3 2.23   8 0.79 0.0259 81.8, 89.0 1.5
NZW/LacJ m 74.2 5.48   8 1.94 0.0739 62.5, 80.8 1.04
P/J f 75.1 8.44   8 2.98 0.112 62.2, 84.1 1.05
P/J m 60.2 5.48   7 2.07 0.091 53.2, 70.8 0.36
PL/J f 59.8 16.6   7 6.29 0.278 23.6, 73.5 0.43
PL/J m 50.8 3.94   6 1.61 0.0776 46.5, 55.8 -0.1
PWD/PhJ f 71.1 10.5   8 3.72 0.148 50.1, 81.6 0.89
PWD/PhJ m 59.1 12.2   8 4.32 0.207 43.4, 79.4 0.31
RIIIS/J f 72.5 5.6   8 1.98 0.0772 65.1, 78.7 0.94
RIIIS/J m 70.2 7.52   8 2.66 0.107 54.0, 77.9 0.85
SJL/J f 28.8 17.8   8 6.29 0.617 9.61, 63.7 -0.82
SJL/J m 41.6 12.8   9 4.25 0.307 16.7, 56.6 -0.55
SM/J f 67.6 3.29   8 1.16 0.0487 63.4, 72.7 0.75
SM/J m 56.5 7.61   8 2.69 0.135 50.1, 73.5 0.18
SWR/J f 57.4 10.9   7 4.14 0.191 37.2, 70.4 0.33
SWR/J m 66.6 3.76   7 1.42 0.0564 60.9, 72.7 0.67
WSB/EiJ f 78.5 4.58   8 1.62 0.0583 68.9, 83.5 1.19
WSB/EiJ m 81.3 2.35   8 0.832 0.029 76.6, 83.7 1.39


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 66.5 3.4678 73.3181 59.6819
129S1/SvImJ m 2.835 3.4678 9.6531 0.0
A/J f 68.0875 3.4678 74.9056 61.2694
A/J m 65.0375 3.4678 71.8556 58.2194
BALB/cByJ f 44.2625 3.4678 51.0806 37.4444
BALB/cByJ m 51.6625 3.4678 58.4806 44.8444
BTBR T+ Itpr3tf/J f 72.3625 3.4678 79.1806 65.5444
BTBR T+ Itpr3tf/J m 69.8429 3.7073 77.1317 62.554
BUB/BnJ f 59.8667 4.0043 67.7395 51.9938
BUB/BnJ m 64.4778 3.2695 70.9059 58.0496
C3H/HeJ f 12.7238 3.4678 19.5418 5.9057
C3H/HeJ m 24.8375 3.4678 31.6556 18.0194
C57BL/10J f 8.4475 3.4678 15.2656 1.6294
C57BL/10J m 40.3286 3.7073 47.6174 33.0398
C57BL/6J f 6.1287 3.4678 12.9468 0.0
C57BL/6J m 31.7375 3.4678 38.5556 24.9194
C57BLKS/J f 55.4625 3.4678 62.2806 48.6444
C57BLKS/J m 64.9125 3.4678 71.7306 58.0944
C57BR/cdJ f 26.4025 3.4678 33.2206 19.5844
C57BR/cdJ m 62.1375 3.4678 68.9556 55.3194
C57L/J f 29.9571 3.7073 37.246 22.6683
C57L/J m 28.3375 3.4678 35.1556 21.5194
CBA/J f 65.475 3.4678 72.2931 58.6569
CBA/J m 76.425 3.4678 83.2431 69.6069
DBA/2J f 46.0 4.0043 53.8728 38.1272
DBA/2J m 67.6143 3.7073 74.9031 60.3255
FVB/NJ f 78.4 3.4678 85.2181 71.5819
FVB/NJ m 72.4 3.4678 79.2181 65.5819
KK/HlJ f 50.025 3.4678 56.8431 43.2069
KK/HlJ m 43.0 3.4678 49.8181 36.1819
LP/J f 60.4286 3.7073 67.7174 53.1398
LP/J m 59.625 3.4678 66.4431 52.8069
MOLF/EiJ f 0.0944 3.7073 7.3832 0.0
MOLF/EiJ m 0.1118 3.2695 6.5399 0.0
MRL/MpJ f 18.0275 3.4678 24.8456 11.2094
MRL/MpJ m 71.05 3.4678 77.8681 64.2319
NON/ShiLtJ f 21.1475 3.4678 27.9656 14.3294
NON/ShiLtJ m 31.9833 4.0043 39.8562 24.1105
NZO/HlLtJ f 32.9429 3.7073 40.2317 25.654
NZO/HlLtJ m 45.6143 3.7073 52.9031 38.3255
NZW/LacJ f 86.3125 3.4678 93.1306 79.4944
NZW/LacJ m 74.175 3.4678 80.9931 67.3569
P/J f 75.15 3.4678 81.9681 68.3319
P/J m 60.2 3.7073 67.4888 52.9112
PL/J f 59.8286 3.7073 67.1174 52.5398
PL/J m 50.8333 4.0043 58.7062 42.9605
PWD/PhJ f 71.1375 3.4678 77.9556 64.3194
PWD/PhJ m 59.125 3.4678 65.9431 52.3069
RIIIS/J f 72.525 3.4678 79.3431 65.7069
RIIIS/J m 70.2375 3.4678 77.0556 63.4194
SJL/J f 28.8388 3.4678 35.6568 22.0207
SJL/J m 41.6 3.2695 48.0281 35.1719
SM/J f 67.55 3.4678 74.3681 60.7319
SM/J m 56.475 3.4678 63.2931 49.6569
SWR/J f 57.4 3.7073 64.6888 50.1112
SWR/J m 66.6143 3.7073 73.9031 59.3255
WSB/EiJ f 78.5375 3.4678 85.3556 71.7194
WSB/EiJ m 81.2875 3.4678 88.1056 74.4694


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 34.6675 2.4521 39.4886 29.8464
A/J both 66.5625 2.4521 71.3836 61.7414
BALB/cByJ both 47.9625 2.4521 52.7836 43.1414
BTBR T+ Itpr3tf/J both 71.1027 2.5382 76.093 66.1124
BUB/BnJ both 62.1722 2.5848 67.2541 57.0903
C3H/HeJ both 18.7806 2.4521 23.6017 13.9595
C57BL/10J both 24.388 2.5382 29.3783 19.3977
C57BL/6J both 18.9331 2.4521 23.7542 14.112
C57BLKS/J both 60.1875 2.4521 65.0086 55.3664
C57BR/cdJ both 44.27 2.4521 49.0911 39.4489
C57L/J both 29.1473 2.5382 34.1376 24.157
CBA/J both 70.95 2.4521 75.7711 66.1289
DBA/2J both 56.8071 2.7285 62.1716 51.4427
FVB/NJ both 75.4 2.4521 80.2211 70.5789
KK/HlJ both 46.5125 2.4521 51.3336 41.6914
LP/J both 60.0268 2.5382 65.0171 55.0365
MOLF/EiJ both 0.1031 2.4715 4.9623 0.0
MRL/MpJ both 44.5388 2.4521 49.3598 39.7177
NON/ShiLtJ both 26.5654 2.6486 31.7728 21.358
NZO/HlLtJ both 39.2786 2.6214 44.4325 34.1246
NZW/LacJ both 80.2437 2.4521 85.0648 75.4227
P/J both 67.675 2.5382 72.6653 62.6847
PL/J both 55.331 2.7285 60.6954 49.9665
PWD/PhJ both 65.1313 2.4521 69.9523 60.3102
RIIIS/J both 71.3812 2.4521 76.2023 66.5602
SJL/J both 35.2194 2.383 39.9046 30.5341
SM/J both 62.0125 2.4521 66.8336 57.1914
SWR/J both 62.0071 2.6214 67.1611 56.8532
WSB/EiJ both 79.9125 2.4521 84.7336 75.0914




  GWAS USING LINEAR MIXED MODELS