Project measure / variable:   Petkova1   CD4_naive_M06

ID, description, units MPD:24233   CD4_naive_M06   CD4 T cells, naive, as percentage of total CD4 T cells   [%]  at age 6mo  
Data set, strains Petkova1   inbred   32 strains     sex: both     age: 26wks
Procedure immune cell quantification
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  STRAIN COMPARISON PLOT
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Petkova1 - CD4 T cells, naive, as percentage of total CD4 T cells at age 6mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested32 strains31 strains
Mean of the strain means28.1   % 33.4   %
Median of the strain means23.3   % 37.9   %
SD of the strain means± 23.8 ± 23.9
Coefficient of variation (CV)0.848 0.715
Min–max range of strain means0.0494   –   71.9   % 0.0766   –   76.9   %
Mean sample size per strain8.0   mice 7.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1700.3477 1700.3477 25.0655 < 0.0001
strain 30 221391.0129 7379.7004 108.7869 < 0.0001
sex:strain 30 55088.8382 1836.2946 27.0695 < 0.0001
Residuals 435 29508.7786 67.8363


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 13.1 5.76   8 2.04 0.439 1.92, 18.5 -0.63
129S1/SvImJ m 4.63 1.12   8 0.396 0.242 3.27, 6.92 -1.2
A/J f 6.46 1.48   8 0.525 0.23 4.41, 8.48 -0.91
A/J m 12.1 2.52   8 0.891 0.208 8.42, 15.2 -0.89
AKR/J f 23.4 10.3   8 3.64 0.439 10.3, 36.2 -0.2
AKR/J m 54.3 11.6   8 4.1 0.214 34.7, 70.5 0.88
BALB/cByJ f 1.99 0.403   8 0.142 0.202 1.5, 2.62 -1.1
BALB/cByJ m 52.3 31.8   8 11.3 0.609 4.22, 80.7 0.79
BTBR T+ Itpr3tf/J f 37.9 5.68   8 2.01 0.15 28.4, 47.8 0.41
BTBR T+ Itpr3tf/J m 38.2 9.08   8 3.21 0.237 28.1, 50.6 0.2
BUB/BnJ f 4.05 2.66   8 0.941 0.657 2.08, 10.1 -1.01
BUB/BnJ m 7.6 1.74   8 0.616 0.229 5.4, 10.2 -1.08
C3H/HeJ f 68.5 5.56   8 1.97 0.0812 62.2, 75.1 1.69
C3H/HeJ m 58.5 11.4   8 4.03 0.195 37.8, 72.5 1.05
C57BL/10J f 49.0 11.5   8 4.06 0.235 31.3, 62.0 0.88
C57BL/10J m 49.2 5.15   8 1.82 0.105 42.1, 57.0 0.66
C57BL/6J f 44.1 10.2   8 3.59 0.231 32.2, 57.0 0.67
C57BL/6J m 57.6 7.49   8 2.65 0.13 45.9, 66.8 1.01
C57BLKS/J f 61.1 5.15   8 1.82 0.0843 52.8, 65.7 1.38
C57BLKS/J m 60.7 3.19   8 1.13 0.0526 55.1, 66.2 1.14
C57BR/cdJ f 22.5 5.31   8 1.88 0.236 15.0, 30.1 -0.24
C57BR/cdJ m 37.9 3.83   8 1.35 0.101 33.6, 44.1 0.19
C57L/J f 32.8 8.11   8 2.87 0.247 21.9, 45.0 0.2
C57L/J m 48.6 8.77   8 3.1 0.18 31.7, 59.4 0.64
CAST/EiJ f 23.2 17.5   6 7.16 0.755 4.37, 44.0 -0.21
CBA/J f 71.9 4.92   8 1.74 0.0684 61.7, 77.8 1.84
CBA/J m 34.2 8.21   8 2.9 0.24 23.4, 48.9 0.03
DBA/2J f 33.4 10.4   8 3.69 0.312 20.0, 45.2 0.22
DBA/2J m 25.8 11.0   8 3.87 0.425 13.2, 47.0 -0.32
FVB/NJ f 38.6 5.29   8 1.87 0.137 29.2, 44.9 0.44
FVB/NJ m 47.9 5.03   8 1.78 0.105 41.9, 56.5 0.61
KK/HlJ f 12.0 11.8   8 4.17 0.98 1.13, 28.5 -0.68
KK/HlJ m 18.5 5.32   8 1.88 0.287 10.9, 25.8 -0.62
LP/J f 6.04 4.65   8 1.64 0.769 1.53, 14.8 -0.93
LP/J m 5.89 3.01   8 1.06 0.51 2.59, 10.7 -1.15
MOLF/EiJ f 0.0494 0.0328   7 0.0124 0.664 0.014, 0.1 -1.18
MOLF/EiJ m 0.0766 0.0314   8 0.0111 0.41 0.028, 0.11 -1.4
MRL/MpJ f 7.33 3.8   8 1.34 0.518 3.19, 14.5 -0.87
MRL/MpJ m 8.03 4.57   8 1.62 0.569 3.51, 17.1 -1.06
NOD.B10Sn-H2b/J f 53.7 13.7   9 4.57 0.255 35.6, 74.9 1.07
NOD.B10Sn-H2b/J m 40.0 8.57   7 3.24 0.214 30.0, 53.5 0.28
NON/ShiLtJ f 3.3 0.56   8 0.198 0.17 2.52, 4.08 -1.04
NON/ShiLtJ m 1.07 0.444   8 0.157 0.416 0.24, 1.68 -1.35
NZO/HlLtJ f 39.4 8.01   8 2.83 0.203 25.1, 50.7 0.47
NZO/HlLtJ m 30.3 6.08   8 2.15 0.201 22.0, 38.9 -0.13
NZW/LacJ f 2.55 1.33   8 0.47 0.521 0.78, 4.66 -1.07
NZW/LacJ m 6.82 1.52   8 0.538 0.223 4.91, 9.06 -1.11
P/J f 2.78 1.53   8 0.539 0.549 1.03, 6.16 -1.06
P/J m 76.9 5.57   8 1.97 0.0723 67.1, 84.3 1.82
PL/J f 67.4 5.98   7 2.26 0.0887 60.6, 75.0 1.65
PL/J m 58.0 8.31   7 3.14 0.143 47.6, 73.4 1.03
PWD/PhJ f 2.89 0.741   8 0.262 0.256 1.93, 3.97 -1.06
PWD/PhJ m 4.4 0.996   8 0.352 0.227 3.46, 6.14 -1.21
RIIIS/J f 33.5 7.8   8 2.76 0.233 20.3, 43.5 0.23
RIIIS/J m 12.0 4.61   8 1.63 0.384 7.13, 19.9 -0.9
SJL/J f 14.4 5.24   8 1.85 0.365 9.11, 24.4 -0.58
SJL/J m 63.5 15.3   6 6.24 0.241 36.8, 77.6 1.26
SM/J f 52.5 13.0   16 3.24 0.247 23.2, 68.4 1.02
SM/J m 60.5 6.29   8 2.22 0.104 50.9, 69.1 1.14
SWR/J f 1.51 1.37   8 0.483 0.907 0.42, 4.72 -1.12
SWR/J m 1.5 0.877   8 0.31 0.586 0.53, 3.09 -1.34
WSB/EiJ f 68.5 12.2   8 4.3 0.178 56.8, 82.9 1.69
WSB/EiJ m 57.9 14.5   6 5.91 0.25 30.0, 69.2 1.03


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 13.1212 2.912 18.8445 7.398
129S1/SvImJ m 4.6262 2.912 10.3495 0.0
A/J f 6.455 2.912 12.1783 0.7317
A/J m 12.1413 2.912 17.8645 6.418
AKR/J f 23.4375 2.912 29.1608 17.7142
AKR/J m 54.325 2.912 60.0483 48.6017
BALB/cByJ f 1.9937 2.912 7.717 0.0
BALB/cByJ m 52.335 2.912 58.0583 46.6117
BTBR T+ Itpr3tf/J f 37.95 2.912 43.6733 32.2267
BTBR T+ Itpr3tf/J m 38.2375 2.912 43.9608 32.5142
BUB/BnJ f 4.0525 2.912 9.7758 0.0
BUB/BnJ m 7.5963 2.912 13.3195 1.873
C3H/HeJ f 68.45 2.912 74.1733 62.7267
C3H/HeJ m 58.475 2.912 64.1983 52.7517
C57BL/10J f 48.9625 2.912 54.6858 43.2392
C57BL/10J m 49.225 2.912 54.9483 43.5017
C57BL/6J f 44.1 2.912 49.8233 38.3767
C57BL/6J m 57.6375 2.912 63.3608 51.9142
C57BLKS/J f 61.1 2.912 66.8233 55.3767
C57BLKS/J m 60.6625 2.912 66.3858 54.9392
C57BR/cdJ f 22.475 2.912 28.1983 16.7517
C57BR/cdJ m 37.8625 2.912 43.5858 32.1392
C57L/J f 32.825 2.912 38.5483 27.1017
C57L/J m 48.5875 2.912 54.3108 42.8642
CBA/J f 71.9 2.912 77.6233 66.1767
CBA/J m 34.1875 2.912 39.9108 28.4642
DBA/2J f 33.4 2.912 39.1233 27.6767
DBA/2J m 25.8 2.912 31.5233 20.0767
FVB/NJ f 38.5875 2.912 44.3108 32.8642
FVB/NJ m 47.8625 2.912 53.5858 42.1392
KK/HlJ f 12.0263 2.912 17.7495 6.303
KK/HlJ m 18.525 2.912 24.2483 12.8017
LP/J f 6.045 2.912 11.7683 0.3217
LP/J m 5.8925 2.912 11.6158 0.1692
MOLF/EiJ f 0.0494 3.113 6.1679 0.0
MOLF/EiJ m 0.0766 2.912 5.7999 0.0
MRL/MpJ f 7.3312 2.912 13.0545 1.608
MRL/MpJ m 8.025 2.912 13.7483 2.3017
NOD.B10Sn-H2b/J f 53.7444 2.7454 59.1404 48.3485
NOD.B10Sn-H2b/J m 40.0429 3.113 46.1613 33.9244
NON/ShiLtJ f 3.3037 2.912 9.027 0.0
NON/ShiLtJ m 1.0687 2.912 6.792 0.0
NZO/HlLtJ f 39.4375 2.912 45.1608 33.7142
NZO/HlLtJ m 30.2875 2.912 36.0108 24.5642
NZW/LacJ f 2.5525 2.912 8.2758 0.0
NZW/LacJ m 6.8225 2.912 12.5458 1.0992
P/J f 2.7812 2.912 8.5045 0.0
P/J m 76.95 2.912 82.6733 71.2267
PL/J f 67.4429 3.113 73.5613 61.3244
PL/J m 57.9714 3.113 64.0899 51.853
PWD/PhJ f 2.8913 2.912 8.6145 0.0
PWD/PhJ m 4.395 2.912 10.1183 0.0
RIIIS/J f 33.5375 2.912 39.2608 27.8142
RIIIS/J m 12.0012 2.912 17.7245 6.278
SJL/J f 14.3637 2.912 20.087 8.6405
SJL/J m 63.4667 3.3624 70.0753 56.858
SM/J f 52.5312 2.0591 56.5782 48.4843
SM/J m 60.4625 2.912 66.1858 54.7392
SWR/J f 1.505 2.912 7.2283 0.0
SWR/J m 1.4963 2.912 7.2195 0.0
WSB/EiJ f 68.525 2.912 74.2483 62.8017
WSB/EiJ m 57.8833 3.3624 64.492 51.2747


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 8.8737 2.0591 12.9207 4.8268
A/J both 9.2981 2.0591 13.3451 5.2512
AKR/J both 38.8813 2.0591 42.9282 34.8343
BALB/cByJ both 27.1644 2.0591 31.2113 23.1174
BTBR T+ Itpr3tf/J both 38.0937 2.0591 42.1407 34.0468
BUB/BnJ both 5.8244 2.0591 9.8713 1.7774
C3H/HeJ both 63.4625 2.0591 67.5095 59.4155
C57BL/10J both 49.0937 2.0591 53.1407 45.0468
C57BL/6J both 50.8688 2.0591 54.9157 46.8218
C57BLKS/J both 60.8813 2.0591 64.9282 56.8343
C57BR/cdJ both 30.1688 2.0591 34.2157 26.1218
C57L/J both 40.7062 2.0591 44.7532 36.6593
CBA/J both 53.0438 2.0591 57.0907 48.9968
DBA/2J both 29.6 2.0591 33.647 25.553
FVB/NJ both 43.225 2.0591 47.272 39.178
KK/HlJ both 15.2756 2.0591 19.3226 11.2287
LP/J both 5.9687 2.0591 10.0157 1.9218
MOLF/EiJ both 0.063 2.1313 4.252 0.0
MRL/MpJ both 7.6781 2.0591 11.7251 3.6312
NOD.B10Sn-H2b/J both 46.8937 2.0753 50.9726 42.8147
NON/ShiLtJ both 2.1862 2.0591 6.2332 0.0
NZO/HlLtJ both 34.8625 2.0591 38.9095 30.8155
NZW/LacJ both 4.6875 2.0591 8.7345 0.6405
P/J both 39.8656 2.0591 43.9126 35.8187
PL/J both 62.7071 2.2012 67.0335 58.3808
PWD/PhJ both 3.6431 2.0591 7.6901 0.0
RIIIS/J both 22.7694 2.0591 26.8163 18.7224
SJL/J both 38.9152 2.224 43.2864 34.544
SM/J both 56.4969 1.7832 60.0016 52.9921
SWR/J both 1.5006 2.0591 5.5476 0.0
WSB/EiJ both 63.2042 2.224 67.5754 58.8329




  GWAS USING LINEAR MIXED MODELS