Project measure / variable:   Petkova1   CD4_all_M18

ID, description, units MPD:24231   CD4_all_M18   CD4 T cells, as percentage of total lymphocytes   [%]  at age 18mo  
Data set, strains Petkova1   inbred   30 strains     sex: both     age: 78wks
Procedure immune cell quantification
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  STRAIN COMPARISON PLOT
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Petkova1 - CD4 T cells, as percentage of total lymphocytes at age 18mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains25 strains
Mean of the strain means16.4   % 18.9   %
Median of the strain means14.9   % 19.0   %
SD of the strain means± 8.52 ± 9.09
Coefficient of variation (CV)0.520 0.481
Min–max range of strain means2.05   –   33.0   % 4.14   –   40.1   %
Mean sample size per strain7.3   mice 6.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 103.6766 103.6766 2.7401 0.099
strain 22 16951.9059 770.5412 20.3649 < 0.0001
sex:strain 22 1248.0991 56.7318 1.4994 0.0728
Residuals 278 10518.5865 37.8366


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 20.9 3.44   7 1.3 0.164 15.4, 25.2 0.53
129S1/SvImJ m 23.8 3.86   8 1.37 0.162 18.5, 29.2 0.54
A/J f 25.7 6.72   8 2.38 0.262 12.6, 34.5 1.1
BALB/cByJ f 15.7 8.23   8 2.91 0.523 0.51, 28.4 -0.08
BALB/cByJ m 20.2 3.63   6 1.48 0.18 16.4, 26.5 0.14
BTBR T+ Itpr3tf/J f 28.5 9.1   8 3.22 0.319 12.2, 41.0 1.42
BTBR T+ Itpr3tf/J m 25.5 6.8   5 3.04 0.267 16.1, 34.7 0.73
BUB/BnJ f 20.9 10.7   8 3.78 0.511 9.26, 39.1 0.53
BUB/BnJ m 23.5 3.22   6 1.31 0.137 19.4, 28.5 0.51
C3H/HeJ f 12.9 2.24   8 0.794 0.174 9.86, 16.2 -0.41
C3H/HeJ m 18.0 5.79   8 2.05 0.322 9.83, 25.8 -0.1
C57BL/10J f 2.05 0.612   7 0.231 0.299 1.17, 2.91 -1.68
C57BL/10J m 4.14 0.0   1   0.0 0.0 4.14, 4.14 -1.62
C57BL/6J f 6.13 3.85   8 1.36 0.629 1.62, 14.2 -1.2
C57BL/6J m 5.14 2.14   7 0.808 0.416 2.51, 8.59 -1.51
C57BLKS/J f 6.8 1.63   7 0.615 0.239 4.46, 9.38 -1.12
C57BR/cdJ f 12.4 4.53   8 1.6 0.367 2.27, 15.3 -0.47
C57BR/cdJ m 11.1 2.49   8 0.88 0.224 7.66, 15.6 -0.86
C57L/J f 7.29 3.98   8 1.41 0.546 2.94, 13.5 -1.07
C57L/J m 8.48 2.15   6 0.876 0.253 5.16, 10.7 -1.14
CBA/J f 14.1 7.52   8 2.66 0.534 4.74, 25.9 -0.27
CBA/J m 16.7 3.89   6 1.59 0.233 11.7, 20.9 -0.24
DBA/2J f 12.2 4.05   7 1.53 0.333 7.7, 20.0 -0.49
DBA/2J m 12.9 5.14   8 1.82 0.399 5.53, 23.6 -0.66
FVB/NJ f 27.9 7.07   8 2.5 0.253 20.6, 43.5 1.35
KK/HlJ f 10.3 3.78   7 1.43 0.367 2.4, 13.7 -0.71
KK/HlJ m 10.2 2.54   7 0.96 0.25 6.73, 14.6 -0.96
LP/J f 17.5 10.1   7 3.83 0.578 0.94, 30.6 0.13
LP/J m 19.7 8.67   8 3.07 0.44 2.39, 29.7 0.09
MOLF/EiJ f 22.9 3.46   9 1.15 0.151 19.7, 29.4 0.77
MOLF/EiJ m 20.3 4.41   7 1.67 0.218 14.1, 28.2 0.16
MRL/MpJ f 13.5 3.79   6 1.55 0.281 7.24, 18.3 -0.34
MRL/MpJ m 22.1 9.47   8 3.35 0.428 11.9, 36.4 0.35
NOD.B10Sn-H2b/J f 5.91 2.93   7 1.11 0.496 2.49, 10.1 -1.23
NOD.B10Sn-H2b/J m 14.9 6.16   6 2.52 0.413 6.92, 23.0 -0.44
NON/ShiLtJ f 12.6 2.18   7 0.824 0.173 9.77, 15.0 -0.44
NON/ShiLtJ m 7.83 1.47   7 0.556 0.188 5.52, 9.84 -1.22
NZO/HlLtJ f 7.2 7.13   3 4.12 0.99 0.81, 14.9 -1.08
NZW/LacJ f 16.6 8.38   8 2.96 0.504 1.15, 28.8 0.03
NZW/LacJ m 19.0 8.65   7 3.27 0.456 6.66, 31.2 0.01
P/J f 14.9 7.72   5 3.45 0.517 6.87, 23.8 -0.17
P/J m 13.1 4.8   4 2.4 0.366 8.94, 17.4 -0.64
PL/J f 30.4 7.78   4 3.89 0.256 25.6, 42.0 1.65
PL/J m 33.9 3.68   5 1.65 0.108 29.9, 39.7 1.65
PWD/PhJ f 18.5 5.26   8 1.86 0.284 9.91, 26.0 0.25
PWD/PhJ m 14.6 4.35   8 1.54 0.297 8.52, 21.2 -0.47
RIIIS/J m 40.1 9.72   8 3.44 0.242 26.3, 53.5 2.34
SJL/J f 31.5 14.2   8 5.03 0.451 16.4, 54.7 1.78
SJL/J m 32.1 4.95   7 1.87 0.154 27.0, 40.6 1.45
SM/J f 7.61 2.58   7 0.976 0.339 3.61, 10.7 -1.03
SWR/J f 18.9 6.32   7 2.39 0.334 12.2, 30.8 0.3
SWR/J m 27.0 4.72   6 1.93 0.175 21.7, 35.6 0.89
WSB/EiJ f 33.0 7.77   8 2.75 0.235 15.7, 41.0 1.95
WSB/EiJ m 27.8 4.14   7 1.56 0.149 22.7, 34.3 0.98


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 20.9429 2.3249 25.5195 16.3662
129S1/SvImJ m 23.8 2.1748 28.0811 19.5189
BALB/cByJ f 15.7388 2.1748 20.0198 11.4577
BALB/cByJ m 20.1667 2.5112 25.11 15.2233
BTBR T+ Itpr3tf/J f 28.5 2.1748 32.7811 24.2189
BTBR T+ Itpr3tf/J m 25.46 2.7509 30.8752 20.0448
BUB/BnJ f 20.92 2.1748 25.2011 16.6389
BUB/BnJ m 23.5 2.5112 28.4434 18.5566
C3H/HeJ f 12.9325 2.1748 17.2136 8.6514
C3H/HeJ m 17.9662 2.1748 22.2473 13.6852
C57BL/6J f 6.1325 2.1748 10.4136 1.8514
C57BL/6J m 5.1371 2.3249 9.7138 0.5605
C57BR/cdJ f 12.3512 2.1748 16.6323 8.0702
C57BR/cdJ m 11.1262 2.1748 15.4073 6.8452
C57L/J f 7.2913 2.1748 11.5723 3.0102
C57L/J m 8.4817 2.5112 13.425 3.5383
CBA/J f 14.0762 2.1748 18.3573 9.7952
CBA/J m 16.7 2.5112 21.6434 11.7566
DBA/2J f 12.1671 2.3249 16.7438 7.5905
DBA/2J m 12.8663 2.1748 17.1473 8.5852
KK/HlJ f 10.3086 2.3249 14.8852 5.7319
KK/HlJ m 10.1529 2.3249 14.7295 5.5762
LP/J f 17.5243 2.3249 22.101 12.9476
LP/J m 19.7363 2.1748 24.0173 15.4552
MOLF/EiJ f 22.9444 2.0504 26.9807 18.9082
MOLF/EiJ m 20.2571 2.3249 24.8338 15.6805
MRL/MpJ f 13.4733 2.5112 18.4167 8.53
MRL/MpJ m 22.1 2.1748 26.3811 17.8189
NOD.B10Sn-H2b/J f 5.9057 2.3249 10.4824 1.329
NOD.B10Sn-H2b/J m 14.9367 2.5112 19.88 9.9933
NON/ShiLtJ f 12.6243 2.3249 17.201 8.0476
NON/ShiLtJ m 7.8257 2.3249 12.4024 3.249
NZW/LacJ f 16.6313 2.1748 20.9123 12.3502
NZW/LacJ m 18.98 2.3249 23.5567 14.4033
P/J f 14.934 2.7509 20.3492 9.5188
P/J m 13.14 3.0756 19.1944 7.0856
PL/J f 30.375 3.0756 36.4294 24.3206
PL/J m 33.94 2.7509 39.3552 28.5248
PWD/PhJ f 18.4887 2.1748 22.7698 14.2077
PWD/PhJ m 14.64 2.1748 18.9211 10.3589
SJL/J f 31.5125 2.1748 35.7936 27.2314
SJL/J m 32.0571 2.3249 36.6338 27.4805
SWR/J f 18.9 2.3249 23.4767 14.3233
SWR/J m 26.9667 2.5112 31.91 22.0233
WSB/EiJ f 33.05 2.1748 37.3311 28.7689
WSB/EiJ m 27.7857 2.3249 32.3624 23.209


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 22.3714 1.5918 25.5049 19.238
BALB/cByJ both 17.9527 1.661 21.2224 14.683
BTBR T+ Itpr3tf/J both 26.98 1.7533 30.4315 23.5285
BUB/BnJ both 22.21 1.661 25.4797 18.9403
C3H/HeJ both 15.4494 1.5378 18.4766 12.4222
C57BL/6J both 5.6348 1.5918 8.7683 2.5014
C57BR/cdJ both 11.7387 1.5378 14.7659 8.7116
C57L/J both 7.8865 1.661 11.1562 4.6167
CBA/J both 15.3881 1.661 18.6579 12.1184
DBA/2J both 12.5167 1.5918 15.6501 9.3833
KK/HlJ both 10.2307 1.644 13.4669 6.9945
LP/J both 18.6303 1.5918 21.7637 15.4968
MOLF/EiJ both 21.6008 1.5499 24.6519 18.5497
MRL/MpJ both 17.7867 1.661 21.0564 14.5169
NOD.B10Sn-H2b/J both 10.4212 1.7111 13.7895 7.0528
NON/ShiLtJ both 10.225 1.644 13.4612 6.9888
NZW/LacJ both 17.8056 1.5918 20.9391 14.6722
P/J both 14.037 2.0632 18.0984 9.9756
PL/J both 32.1575 2.0632 36.2189 28.0961
PWD/PhJ both 16.5644 1.5378 19.5916 13.5372
SJL/J both 31.7848 1.5918 34.9183 28.6514
SWR/J both 22.9333 1.7111 26.3017 19.565
WSB/EiJ both 30.4179 1.5918 33.5513 27.2844




  GWAS USING LINEAR MIXED MODELS