Project measure / variable:   Petkova1   CD4_all_M12

ID, description, units MPD:24230   CD4_all_M12   CD4 T cells, as percentage of total lymphocytes   [%]  at age 12mo  
Data set, strains Petkova1   inbred   31 strains     sex: both     age: 52wks
Procedure immune cell quantification
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  STRAIN COMPARISON PLOT
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Petkova1 - CD4 T cells, as percentage of total lymphocytes at age 12mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested30 strains30 strains
Mean of the strain means22.5   % 19.2   %
Median of the strain means19.5   % 19.1   %
SD of the strain means± 13.3 ± 11.0
Coefficient of variation (CV)0.589 0.572
Min–max range of strain means2.30   –   55.1   % 3.56   –   48.4   %
Mean sample size per strain7.6   mice 7.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1322.4501 1322.4501 45.571 < 0.0001
strain 28 59923.6683 2140.131 73.7479 < 0.0001
sex:strain 28 4891.9626 174.7129 6.0205 < 0.0001
Residuals 389 11288.6029 29.0195


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 38.6 1.32   8 0.466 0.0341 35.8, 39.6 1.21
129S1/SvImJ m 13.4 3.39   8 1.2 0.253 6.49, 17.7 -0.53
A/J f 30.8 5.38   8 1.9 0.175 21.8, 39.5 0.62
A/J m 17.8 4.6   8 1.63 0.259 12.9, 27.3 -0.13
AKR/J m 9.92 6.32   5 2.83 0.637 0.18, 17.2 -0.85
BALB/cByJ f 27.7 3.61   8 1.28 0.13 20.7, 31.6 0.39
BALB/cByJ m 20.3 5.78   8 2.04 0.285 13.5, 28.1 0.1
BTBR T+ Itpr3tf/J f 43.3 3.11   8 1.1 0.0719 39.7, 48.1 1.56
BTBR T+ Itpr3tf/J m 37.2 4.32   7 1.63 0.116 31.2, 44.0 1.63
BUB/BnJ f 28.5 6.62   6 2.7 0.232 19.6, 36.4 0.45
BUB/BnJ m 20.4 3.22   9 1.07 0.157 14.7, 25.2 0.11
C3H/HeJ f 10.7 2.63   8 0.931 0.246 6.59, 13.2 -0.89
C3H/HeJ m 8.51 1.95   8 0.689 0.229 4.54, 11.0 -0.97
C57BL/10J f 2.3 0.498   8 0.176 0.216 1.62, 2.9 -1.52
C57BL/10J m 3.56 1.23   7 0.465 0.346 2.11, 6.1 -1.42
C57BL/6J f 3.96 1.16   8 0.411 0.293 2.82, 6.31 -1.4
C57BL/6J m 4.56 1.02   8 0.359 0.223 3.2, 6.61 -1.33
C57BLKS/J f 8.27 1.92   8 0.678 0.232 6.77, 12.8 -1.08
C57BLKS/J m 9.05 1.34   8 0.475 0.148 7.7, 11.5 -0.92
C57BR/cdJ f 14.9 2.57   8 0.908 0.172 10.9, 18.2 -0.58
C57BR/cdJ m 12.4 2.57   8 0.908 0.208 8.89, 16.8 -0.62
C57L/J f 9.83 3.14   7 1.19 0.319 4.99, 13.7 -0.96
C57L/J m 7.21 1.5   8 0.53 0.208 5.38, 9.4 -1.09
CAST/EiJ f 7.98 1.0   3 0.578 0.125 6.88, 8.84 -1.1
CBA/J f 22.9 3.76   8 1.33 0.165 18.5, 27.7 0.03
CBA/J m 22.0 4.17   8 1.47 0.189 13.6, 25.4 0.25
DBA/2J f 16.9 7.0   6 2.86 0.413 11.3, 30.0 -0.42
DBA/2J m 20.3 4.12   7 1.56 0.202 16.4, 27.4 0.1
FVB/NJ f 39.6 4.9   8 1.73 0.124 32.7, 45.3 1.29
FVB/NJ m 37.6 5.59   8 1.98 0.149 25.5, 43.8 1.67
KK/HlJ f 10.1 2.18   8 0.772 0.216 6.87, 13.1 -0.94
KK/HlJ m 14.1 5.67   8 2.01 0.402 6.22, 22.8 -0.47
LP/J f 23.4 14.8   7 5.59 0.632 3.49, 40.7 0.06
LP/J m 30.3 15.3   8 5.41 0.505 4.14, 51.8 1.01
MOLF/EiJ f 18.4 2.51   7 0.949 0.137 14.3, 21.4 -0.31
MOLF/EiJ m 20.7 3.88   9 1.29 0.188 16.3, 26.5 0.13
MRL/MpJ f 12.3 6.9   8 2.44 0.56 5.71, 26.6 -0.77
MRL/MpJ m 15.4 6.22   8 2.2 0.404 9.66, 24.2 -0.35
NON/ShiLtJ f 10.1 4.87   8 1.72 0.48 4.66, 18.3 -0.94
NON/ShiLtJ m 5.82 1.03   6 0.419 0.176 4.8, 7.32 -1.22
NZO/HlLtJ f 18.7 6.3   7 2.38 0.336 6.54, 26.9 -0.29
NZO/HlLtJ m 12.5 1.85   7 0.701 0.149 10.4, 15.3 -0.61
NZW/LacJ f 33.8 3.27   8 1.16 0.0967 29.3, 40.8 0.85
NZW/LacJ m 30.0 5.44   8 1.92 0.181 20.6, 35.6 0.98
P/J f 17.2 9.1   8 3.22 0.529 7.31, 33.1 -0.4
P/J m 10.8 4.77   7 1.8 0.441 6.0, 17.2 -0.77
PL/J f 33.9 8.36   7 3.16 0.247 15.5, 40.7 0.86
PL/J m 25.8 4.38   6 1.79 0.17 19.6, 32.3 0.6
PWD/PhJ f 20.3 3.7   8 1.31 0.182 15.3, 25.7 -0.17
PWD/PhJ m 22.4 3.2   8 1.13 0.143 16.2, 27.5 0.29
RIIIS/J f 55.1 4.94   8 1.75 0.0897 49.2, 62.3 2.45
RIIIS/J m 48.4 6.24   8 2.21 0.129 37.0, 55.2 2.65
SJL/J f 38.7 10.5   8 3.69 0.27 24.3, 56.6 1.22
SJL/J m 26.0 8.39   9 2.8 0.322 16.7, 39.6 0.62
SM/J f 14.2 2.42   8 0.856 0.17 9.09, 16.9 -0.63
SM/J m 10.2 2.3   8 0.815 0.226 7.13, 12.9 -0.82
SWR/J f 23.7 5.41   7 2.04 0.228 16.4, 31.5 0.09
SWR/J m 29.7 7.74   7 2.93 0.261 23.8, 45.1 0.95
WSB/EiJ f 40.1 5.12   8 1.81 0.128 31.1, 46.8 1.32
WSB/EiJ m 30.4 4.21   8 1.49 0.138 22.4, 37.5 1.02


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 38.6375 1.9046 42.3821 34.8929
129S1/SvImJ m 13.3863 1.9046 17.1308 9.6417
A/J f 30.775 1.9046 34.5196 27.0304
A/J m 17.7625 1.9046 21.5071 14.0179
BALB/cByJ f 27.7 1.9046 31.4446 23.9554
BALB/cByJ m 20.2875 1.9046 24.0321 16.5429
BTBR T+ Itpr3tf/J f 43.3375 1.9046 47.0821 39.5929
BTBR T+ Itpr3tf/J m 37.1857 2.0361 41.1888 33.1826
BUB/BnJ f 28.5167 2.1992 32.8405 24.1928
BUB/BnJ m 20.4333 1.7957 23.9637 16.9029
C3H/HeJ f 10.6963 1.9046 14.4408 6.9517
C3H/HeJ m 8.5062 1.9046 12.2508 4.7617
C57BL/10J f 2.2987 1.9046 6.0433 0.0
C57BL/10J m 3.5557 2.0361 7.5588 0.0
C57BL/6J f 3.965 1.9046 7.7096 0.2204
C57BL/6J m 4.56 1.9046 8.3046 0.8154
C57BLKS/J f 8.2688 1.9046 12.0133 4.5242
C57BLKS/J m 9.055 1.9046 12.7996 5.3104
C57BR/cdJ f 14.9 1.9046 18.6446 11.1554
C57BR/cdJ m 12.3688 1.9046 16.1133 8.6242
C57L/J f 9.8343 2.0361 13.8374 5.8312
C57L/J m 7.215 1.9046 10.9596 3.4704
CBA/J f 22.85 1.9046 26.5946 19.1054
CBA/J m 22.0125 1.9046 25.7571 18.2679
DBA/2J f 16.95 2.1992 21.2739 12.6261
DBA/2J m 20.3429 2.0361 24.346 16.3397
FVB/NJ f 39.6125 1.9046 43.3571 35.8679
FVB/NJ m 37.6375 1.9046 41.3821 33.8929
KK/HlJ f 10.0938 1.9046 13.8383 6.3492
KK/HlJ m 14.1012 1.9046 17.8458 10.3567
LP/J f 23.4271 2.0361 27.4303 19.424
LP/J m 30.28 1.9046 34.0246 26.5354
MOLF/EiJ f 18.3714 2.0361 22.3745 14.3683
MOLF/EiJ m 20.6778 1.7957 24.2082 17.1474
MRL/MpJ f 12.3263 1.9046 16.0708 8.5817
MRL/MpJ m 15.4062 1.9046 19.1508 11.6617
NON/ShiLtJ f 10.1425 1.9046 13.8871 6.3979
NON/ShiLtJ m 5.8167 2.1992 10.1405 1.4928
NZO/HlLtJ f 18.7486 2.0361 22.7517 14.7455
NZO/HlLtJ m 12.4714 2.0361 16.4745 8.4683
NZW/LacJ f 33.8125 1.9046 37.5571 30.0679
NZW/LacJ m 29.9875 1.9046 33.7321 26.2429
P/J f 17.2125 1.9046 20.9571 13.4679
P/J m 10.8 2.0361 14.8031 6.7969
PL/J f 33.8714 2.0361 37.8745 29.8683
PL/J m 25.75 2.1992 30.0739 21.4261
PWD/PhJ f 20.3 1.9046 24.0446 16.5554
PWD/PhJ m 22.3875 1.9046 26.1321 18.6429
RIIIS/J f 55.0875 1.9046 58.8321 51.3429
RIIIS/J m 48.45 1.9046 52.1946 44.7054
SJL/J f 38.6875 1.9046 42.4321 34.9429
SJL/J m 26.0444 1.7957 29.5749 22.514
SM/J f 14.2488 1.9046 17.9933 10.5042
SM/J m 10.2062 1.9046 13.9508 6.4617
SWR/J f 23.7143 2.0361 27.7174 19.7112
SWR/J m 29.6571 2.0361 33.6603 25.654
WSB/EiJ f 40.1 1.9046 43.8446 36.3554
WSB/EiJ m 30.4375 1.9046 34.1821 26.6929


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 26.0119 1.3467 28.6597 23.3641
A/J both 24.2687 1.3467 26.9166 21.6209
BALB/cByJ both 23.9937 1.3467 26.6416 21.3459
BTBR T+ Itpr3tf/J both 40.2616 1.394 43.0024 37.5209
BUB/BnJ both 24.475 1.4196 27.266 21.684
C3H/HeJ both 9.6013 1.3467 12.2491 6.9534
C57BL/10J both 2.9272 1.394 5.668 0.1865
C57BL/6J both 4.2625 1.3467 6.9103 1.6147
C57BLKS/J both 8.6619 1.3467 11.3097 6.0141
C57BR/cdJ both 13.6344 1.3467 16.2822 10.9866
C57L/J both 8.5246 1.394 11.2654 5.7839
CBA/J both 22.4312 1.3467 25.0791 19.7834
DBA/2J both 18.6464 1.4985 21.5926 15.7002
FVB/NJ both 38.625 1.3467 41.2728 35.9772
KK/HlJ both 12.0975 1.3467 14.7453 9.4497
LP/J both 26.8536 1.394 29.5943 24.1128
MOLF/EiJ both 19.5246 1.3574 22.1933 16.8559
MRL/MpJ both 13.8663 1.3467 16.5141 11.2184
NON/ShiLtJ both 7.9796 1.4547 10.8395 5.1196
NZO/HlLtJ both 15.61 1.4397 18.4406 12.7794
NZW/LacJ both 31.9 1.3467 34.5478 29.2522
P/J both 14.0062 1.394 16.747 11.2655
PL/J both 29.8107 1.4985 32.7569 26.8645
PWD/PhJ both 21.3437 1.3467 23.9916 18.6959
RIIIS/J both 51.7687 1.3467 54.4166 49.1209
SJL/J both 32.366 1.3088 34.9392 29.7928
SM/J both 12.2275 1.3467 14.8753 9.5797
SWR/J both 26.6857 1.4397 29.5163 23.8551
WSB/EiJ both 35.2687 1.3467 37.9166 32.6209




  GWAS USING LINEAR MIXED MODELS