Project measure / variable:   Petkova1   CD4_all_M06

ID, description, units MPD:24229   CD4_all_M06   CD4 T cells, as percentage of total lymphocytes   [%]  at age 6mo  
Data set, strains Petkova1   inbred   32 strains     sex: both     age: 26wks
Procedure immune cell quantification
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  STRAIN COMPARISON PLOT
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Petkova1 - CD4 T cells, as percentage of total lymphocytes at age 6mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested32 strains31 strains
Mean of the strain means18.6   % 16.9   %
Median of the strain means13.9   % 14.1   %
SD of the strain means± 13.7 ± 11.8
Coefficient of variation (CV)0.734 0.700
Min–max range of strain means1.90   –   51.4   % 2.69   –   44.2   %
Mean sample size per strain8.0   mice 7.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 442.3469 442.3469 27.9872 < 0.0001
strain 30 67339.7814 2244.6594 142.019 < 0.0001
sex:strain 30 10665.5738 355.5191 22.4936 < 0.0001
Residuals 435 6875.3263 15.8053


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 7.78 7.5   8 2.65 0.963 2.9, 25.9 -0.79
129S1/SvImJ m 5.9 0.785   8 0.277 0.133 4.79, 7.51 -0.93
A/J f 12.8 5.56   8 1.97 0.435 8.3, 25.3 -0.43
A/J m 4.2 1.97   8 0.697 0.47 2.73, 8.87 -1.07
AKR/J f 6.84 3.29   8 1.16 0.482 2.33, 10.9 -0.86
AKR/J m 19.9 6.22   8 2.2 0.313 13.7, 32.6 0.26
BALB/cByJ f 16.6 2.56   8 0.905 0.155 13.4, 20.4 -0.15
BALB/cByJ m 24.9 5.04   8 1.78 0.203 14.9, 32.1 0.68
BTBR T+ Itpr3tf/J f 33.1 4.92   8 1.74 0.148 25.0, 38.2 1.06
BTBR T+ Itpr3tf/J m 29.6 3.57   8 1.26 0.121 25.5, 36.1 1.08
BUB/BnJ f 14.4 6.0   8 2.12 0.416 5.33, 22.9 -0.31
BUB/BnJ m 10.9 2.04   8 0.72 0.187 8.19, 13.8 -0.51
C3H/HeJ f 28.4 2.84   8 1.01 0.1 22.1, 31.1 0.72
C3H/HeJ m 20.5 7.02   8 2.48 0.343 6.8, 28.8 0.31
C57BL/10J f 1.9 0.417   8 0.147 0.22 1.35, 2.63 -1.22
C57BL/10J m 4.35 1.45   8 0.514 0.334 2.39, 6.47 -1.06
C57BL/6J f 7.48 1.84   8 0.649 0.245 3.93, 9.67 -0.82
C57BL/6J m 4.19 1.63   8 0.575 0.389 2.22, 7.3 -1.07
C57BLKS/J f 8.92 1.98   8 0.701 0.222 6.34, 12.3 -0.71
C57BLKS/J m 14.1 3.07   8 1.09 0.218 9.8, 18.7 -0.24
C57BR/cdJ f 9.98 4.53   8 1.6 0.454 4.22, 17.4 -0.63
C57BR/cdJ m 9.3 2.21   8 0.782 0.238 6.92, 13.2 -0.64
C57L/J f 7.13 2.01   8 0.709 0.281 3.36, 9.54 -0.84
C57L/J m 4.7 1.34   8 0.473 0.284 2.79, 6.48 -1.03
CAST/EiJ f 15.3 1.43   6 0.582 0.0931 13.1, 16.7 -0.24
CBA/J f 24.1 1.62   8 0.574 0.0674 22.2, 26.8 0.4
CBA/J m 14.6 4.9   8 1.73 0.336 5.13, 20.9 -0.19
DBA/2J f 2.84 1.16   8 0.41 0.408 1.31, 4.75 -1.15
DBA/2J m 18.2 5.24   8 1.85 0.288 13.3, 29.7 0.11
FVB/NJ f 36.0 4.91   8 1.73 0.136 28.0, 41.9 1.27
FVB/NJ m 19.9 4.68   8 1.66 0.235 13.4, 26.3 0.26
KK/HlJ f 8.42 4.05   8 1.43 0.48 4.49, 14.3 -0.75
KK/HlJ m 6.35 1.77   8 0.626 0.279 4.59, 9.58 -0.89
LP/J f 16.0 9.51   8 3.36 0.596 4.75, 32.3 -0.19
LP/J m 7.69 3.37   8 1.19 0.439 1.17, 11.5 -0.78
MOLF/EiJ f 22.0 5.5   7 2.08 0.25 14.2, 31.5 0.25
MOLF/EiJ m 22.7 5.1   8 1.8 0.225 14.8, 30.4 0.49
MRL/MpJ f 11.5 3.78   8 1.34 0.329 6.87, 18.8 -0.52
MRL/MpJ m 11.4 3.1   8 1.1 0.273 6.66, 17.1 -0.46
NOD.B10Sn-H2b/J f 30.9 5.31   9 1.77 0.172 23.4, 42.8 0.9
NOD.B10Sn-H2b/J m 18.9 1.75   7 0.663 0.0929 16.4, 21.2 0.17
NON/ShiLtJ f 4.65 1.86   8 0.659 0.401 2.55, 8.52 -1.02
NON/ShiLtJ m 2.69 0.584   8 0.206 0.217 2.0, 3.8 -1.2
NZO/HlLtJ f 15.5 5.09   8 1.8 0.328 8.36, 23.1 -0.23
NZO/HlLtJ m 11.9 3.88   8 1.37 0.327 5.47, 17.5 -0.42
NZW/LacJ f 5.65 1.99   8 0.702 0.351 3.08, 9.01 -0.95
NZW/LacJ m 5.63 0.928   8 0.328 0.165 4.38, 7.2 -0.95
P/J f 13.3 4.13   8 1.46 0.311 6.86, 21.2 -0.39
P/J m 44.2 4.22   8 1.49 0.0954 37.8, 48.8 2.31
PL/J f 51.4 4.28   7 1.62 0.0832 47.3, 56.4 2.4
PL/J m 41.1 2.02   7 0.762 0.049 38.8, 44.8 2.05
PWD/PhJ f 38.2 2.32   8 0.822 0.0608 35.8, 41.5 1.43
PWD/PhJ m 29.7 2.88   8 1.02 0.097 24.7, 33.3 1.08
RIIIS/J f 40.0 6.13   8 2.17 0.153 30.7, 50.7 1.56
RIIIS/J m 41.1 2.35   8 0.831 0.0572 37.6, 43.9 2.05
SJL/J f 47.7 2.91   8 1.03 0.0609 43.3, 52.8 2.13
SJL/J m 28.8 9.15   6 3.74 0.317 17.9, 40.5 1.01
SM/J f 13.4 2.28   16 0.571 0.171 10.5, 18.8 -0.38
SM/J m 10.8 1.77   8 0.625 0.164 7.45, 12.6 -0.51
SWR/J f 8.81 3.87   8 1.37 0.439 1.79, 13.4 -0.72
SWR/J m 7.61 2.26   8 0.8 0.297 4.15, 11.5 -0.78
WSB/EiJ f 35.0 4.42   8 1.56 0.126 29.1, 43.1 1.2
WSB/EiJ m 27.5 2.79   6 1.14 0.101 23.2, 30.9 0.9


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 7.7837 1.4056 10.5463 5.0212
129S1/SvImJ m 5.9 1.4056 8.6626 3.1374
A/J f 12.79 1.4056 15.5526 10.0274
A/J m 4.1963 1.4056 6.9588 1.4337
AKR/J f 6.8363 1.4056 9.5988 4.0737
AKR/J m 19.875 1.4056 22.6376 17.1124
BALB/cByJ f 16.5625 1.4056 19.3251 13.7999
BALB/cByJ m 24.875 1.4056 27.6376 22.1124
BTBR T+ Itpr3tf/J f 33.1125 1.4056 35.8751 30.3499
BTBR T+ Itpr3tf/J m 29.5875 1.4056 32.3501 26.8249
BUB/BnJ f 14.4013 1.4056 17.1638 11.6387
BUB/BnJ m 10.8863 1.4056 13.6488 8.1237
C3H/HeJ f 28.375 1.4056 31.1376 25.6124
C3H/HeJ m 20.4625 1.4056 23.2251 17.6999
C57BL/10J f 1.8988 1.4056 4.6613 0.0
C57BL/10J m 4.3513 1.4056 7.1138 1.5887
C57BL/6J f 7.4825 1.4056 10.2451 4.7199
C57BL/6J m 4.1875 1.4056 6.9501 1.4249
C57BLKS/J f 8.9187 1.4056 11.6813 6.1562
C57BLKS/J m 14.1125 1.4056 16.8751 11.3499
C57BR/cdJ f 9.9775 1.4056 12.7401 7.2149
C57BR/cdJ m 9.3 1.4056 12.0626 6.5374
C57L/J f 7.1287 1.4056 9.8913 4.3662
C57L/J m 4.7012 1.4056 7.4638 1.9387
CBA/J f 24.1 1.4056 26.8626 21.3374
CBA/J m 14.5788 1.4056 17.3413 11.8162
DBA/2J f 2.8412 1.4056 5.6038 0.0787
DBA/2J m 18.225 1.4056 20.9876 15.4624
FVB/NJ f 35.95 1.4056 38.7126 33.1874
FVB/NJ m 19.9125 1.4056 22.6751 17.1499
KK/HlJ f 8.4225 1.4056 11.1851 5.6599
KK/HlJ m 6.3538 1.4056 9.1163 3.5912
LP/J f 15.9525 1.4056 18.7151 13.1899
LP/J m 7.685 1.4056 10.4476 4.9224
MOLF/EiJ f 22.0286 1.5026 24.9819 19.0752
MOLF/EiJ m 22.675 1.4056 25.4376 19.9124
MRL/MpJ f 11.475 1.4056 14.2376 8.7124
MRL/MpJ m 11.3663 1.4056 14.1288 8.6037
NOD.B10Sn-H2b/J f 30.8667 1.3252 33.4713 28.2621
NOD.B10Sn-H2b/J m 18.8857 1.5026 21.839 15.9324
NON/ShiLtJ f 4.6512 1.4056 7.4138 1.8887
NON/ShiLtJ m 2.695 1.4056 5.4576 0.0
NZO/HlLtJ f 15.53 1.4056 18.2926 12.7674
NZO/HlLtJ m 11.8712 1.4056 14.6338 9.1087
NZW/LacJ f 5.6525 1.4056 8.4151 2.8899
NZW/LacJ m 5.6275 1.4056 8.3901 2.8649
P/J f 13.2575 1.4056 16.0201 10.4949
P/J m 44.1875 1.4056 46.9501 41.4249
PL/J f 51.4429 1.5026 54.3962 48.4895
PL/J m 41.1286 1.5026 44.0819 38.1752
PWD/PhJ f 38.2375 1.4056 41.0001 35.4749
PWD/PhJ m 29.7 1.4056 32.4626 26.9374
RIIIS/J f 40.05 1.4056 42.8126 37.2874
RIIIS/J m 41.1125 1.4056 43.8751 38.3499
SJL/J f 47.725 1.4056 50.4876 44.9624
SJL/J m 28.85 1.623 32.04 25.66
SM/J f 13.375 0.9939 15.3284 11.4216
SM/J m 10.7637 1.4056 13.5263 8.0012
SWR/J f 8.8075 1.4056 11.5701 6.0449
SWR/J m 7.61 1.4056 10.3726 4.8474
WSB/EiJ f 35.025 1.4056 37.7876 32.2624
WSB/EiJ m 27.5333 1.623 30.7233 24.3434


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 6.8419 0.9939 8.7953 4.8884
A/J both 8.4931 0.9939 10.4466 6.5397
AKR/J both 13.3556 0.9939 15.3091 11.4022
BALB/cByJ both 20.7187 0.9939 22.6722 18.7653
BTBR T+ Itpr3tf/J both 31.35 0.9939 33.3034 29.3966
BUB/BnJ both 12.6438 0.9939 14.5972 10.6903
C3H/HeJ both 24.4187 0.9939 26.3722 22.4653
C57BL/10J both 3.125 0.9939 5.0784 1.1716
C57BL/6J both 5.835 0.9939 7.7884 3.8816
C57BLKS/J both 11.5156 0.9939 13.4691 9.5622
C57BR/cdJ both 9.6388 0.9939 11.5922 7.6853
C57L/J both 5.915 0.9939 7.8684 3.9616
CBA/J both 19.3394 0.9939 21.2928 17.3859
DBA/2J both 10.5331 0.9939 12.4866 8.5797
FVB/NJ both 27.9312 0.9939 29.8847 25.9778
KK/HlJ both 7.3881 0.9939 9.3416 5.4347
LP/J both 11.8187 0.9939 13.7722 9.8653
MOLF/EiJ both 22.3518 1.0288 24.3738 20.3298
MRL/MpJ both 11.4206 0.9939 13.3741 9.4672
NOD.B10Sn-H2b/J both 24.8762 1.0018 26.8451 22.9073
NON/ShiLtJ both 3.6731 0.9939 5.6266 1.7197
NZO/HlLtJ both 13.7006 0.9939 15.6541 11.7472
NZW/LacJ both 5.64 0.9939 7.5934 3.6866
P/J both 28.7225 0.9939 30.6759 26.7691
PL/J both 46.2857 1.0625 48.374 44.1974
PWD/PhJ both 33.9688 0.9939 35.9222 32.0153
RIIIS/J both 40.5812 0.9939 42.5347 38.6278
SJL/J both 38.2875 1.0735 40.3975 36.1775
SM/J both 12.0694 0.8607 13.7611 10.3776
SWR/J both 8.2087 0.9939 10.1622 6.2553
WSB/EiJ both 31.2792 1.0735 33.3891 29.1692




  GWAS USING LINEAR MIXED MODELS