Project measure / variable:   Petkova1   EOS_M12

ID, description, units MPD:24217   EOS_M12   eosinophil differential (EOS; percentage of total WBC)   [%]  at age 12mo  
Data set, strains Petkova1   inbred   31 strains     sex: both     age: 52wks
Procedure immune cell quantification
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  STRAIN COMPARISON PLOT
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Petkova1 - eosinophil differential (EOS; percentage of total WBC) at age 12mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested30 strains30 strains
Mean of the strain means3.34   % 3.39   %
Median of the strain means3.23   % 3.26   %
SD of the strain means± 1.72 ± 1.60
Coefficient of variation (CV)0.516 0.471
Min–max range of strain means0.954   –   9.52   % 1.05   –   7.12   %
Mean sample size per strain7.6   mice 7.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0296 0.0296 0.0123 0.9116
strain 28 990.7429 35.3837 14.7613 < 0.0001
sex:strain 28 257.0452 9.1802 3.8298 < 0.0001
Residuals 388 930.0591 2.3971


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 9.52 5.45   8 1.93 0.573 2.81, 16.9 3.58
129S1/SvImJ m 5.08 2.07   8 0.73 0.407 1.89, 7.97 1.05
A/J f 1.6 0.27   8 0.0953 0.168 1.28, 1.95 -1.01
A/J m 2.51 0.427   8 0.151 0.17 1.61, 3.11 -0.55
AKR/J m 4.16 2.64   5 1.18 0.636 2.39, 8.81 0.48
BALB/cByJ f 4.3 1.22   8 0.43 0.283 2.57, 6.04 0.56
BALB/cByJ m 4.26 1.64   8 0.581 0.386 1.86, 7.2 0.54
BTBR T+ Itpr3tf/J f 1.61 0.713   8 0.252 0.443 1.12, 3.3 -1.0
BTBR T+ Itpr3tf/J m 2.0 0.798   7 0.301 0.4 1.26, 3.07 -0.87
BUB/BnJ f 2.57 0.857   6 0.35 0.333 1.66, 3.61 -0.45
BUB/BnJ m 1.05 0.671   9 0.224 0.639 0.16, 2.29 -1.47
C3H/HeJ f 2.26 0.5   8 0.177 0.221 1.35, 2.94 -0.63
C3H/HeJ m 2.46 0.656   8 0.232 0.267 1.77, 3.85 -0.58
C57BL/10J f 5.34 2.89   8 1.02 0.541 3.27, 11.9 1.16
C57BL/10J m 5.04 1.58   7 0.596 0.313 3.19, 8.19 1.03
C57BL/6J f 4.04 1.01   8 0.359 0.251 2.82, 5.36 0.41
C57BL/6J m 3.71 1.03   8 0.363 0.277 2.61, 5.79 0.2
C57BLKS/J f 4.81 2.48   8 0.878 0.516 2.1, 10.4 0.85
C57BLKS/J m 6.12 1.13   8 0.4 0.185 4.8, 7.61 1.7
C57BR/cdJ f 2.63 0.62   8 0.219 0.236 1.47, 3.4 -0.41
C57BR/cdJ m 3.34 0.921   8 0.326 0.276 2.25, 5.25 -0.03
C57L/J f 2.13 0.957   7 0.362 0.45 0.88, 4.03 -0.7
C57L/J m 3.25 0.551   8 0.195 0.17 2.22, 3.92 -0.09
CAST/EiJ f 2.29 0.668   3 0.386 0.292 1.87, 3.06 -0.61
CBA/J f 2.4 1.24   8 0.439 0.519 0.26, 3.72 -0.54
CBA/J m 2.06 0.652   8 0.23 0.316 1.44, 3.08 -0.83
DBA/2J f 3.85 2.67   6 1.09 0.694 1.59, 8.87 0.3
DBA/2J m 1.19 0.758   7 0.286 0.634 0.38, 2.62 -1.38
FVB/NJ f 2.54 0.855   8 0.302 0.337 1.65, 3.82 -0.46
FVB/NJ m 4.05 0.657   8 0.232 0.162 3.21, 4.9 0.41
KK/HlJ f 3.54 0.848   8 0.3 0.239 2.22, 4.63 0.12
KK/HlJ m 7.12 1.69   8 0.598 0.237 4.52, 10.0 2.33
LP/J f 3.48 1.5   7 0.565 0.43 2.22, 6.6 0.08
LP/J m 4.91 1.84   8 0.651 0.375 2.36, 8.4 0.95
MOLF/EiJ f 3.66 1.6   7 0.604 0.437 2.08, 6.65 0.19
MOLF/EiJ m 3.82 3.2   9 1.07 0.837 1.99, 12.1 0.27
MRL/MpJ f 5.44 1.54   8 0.543 0.282 3.66, 8.63 1.22
MRL/MpJ m 4.88 2.46   8 0.869 0.504 1.03, 7.58 0.93
NON/ShiLtJ f 2.45 0.791   8 0.28 0.322 1.74, 3.79 -0.52
NON/ShiLtJ m 3.23 1.01   6 0.411 0.311 2.16, 4.77 -0.1
NZO/HlLtJ f 3.23 0.221   6 0.0904 0.0685 2.97, 3.58 -0.06
NZO/HlLtJ m 1.75 1.08   7 0.409 0.617 0.59, 3.71 -1.03
NZW/LacJ f 1.01 0.236   8 0.0835 0.235 0.64, 1.31 -1.35
NZW/LacJ m 1.67 0.629   8 0.222 0.377 0.98, 2.89 -1.08
P/J f 2.54 0.59   8 0.209 0.233 1.82, 3.55 -0.46
P/J m 1.91 0.619   7 0.234 0.324 1.07, 2.68 -0.93
PL/J f 3.23 1.68   7 0.635 0.519 1.4, 6.13 -0.06
PL/J m 5.37 0.607   6 0.248 0.113 4.95, 6.58 1.24
PWD/PhJ f 5.04 1.78   8 0.628 0.353 3.54, 9.11 0.99
PWD/PhJ m 2.87 0.543   8 0.192 0.189 2.16, 3.86 -0.33
RIIIS/J f 1.11 0.601   8 0.212 0.539 0.29, 2.0 -1.29
RIIIS/J m 1.58 0.418   8 0.148 0.264 1.04, 2.41 -1.13
SJL/J f 4.47 2.58   8 0.911 0.576 1.97, 9.64 0.66
SJL/J m 3.28 1.61   9 0.537 0.491 1.92, 6.87 -0.07
SM/J f 0.954 0.469   8 0.166 0.492 0.34, 1.88 -1.38
SM/J m 1.14 0.511   8 0.181 0.449 0.51, 2.16 -1.41
SWR/J f 3.59 1.08   7 0.406 0.3 2.24, 5.34 0.15
SWR/J m 2.62 0.9   7 0.34 0.344 1.71, 4.43 -0.48
WSB/EiJ f 4.55 1.54   8 0.545 0.339 2.43, 7.38 0.7
WSB/EiJ m 5.38 2.27   8 0.802 0.421 2.34, 8.03 1.24


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 9.515 0.5474 10.5912 8.4388
129S1/SvImJ m 5.075 0.5474 6.1512 3.9988
A/J f 1.605 0.5474 2.6812 0.5288
A/J m 2.5137 0.5474 3.59 1.4375
BALB/cByJ f 4.2963 0.5474 5.3725 3.22
BALB/cByJ m 4.2625 0.5474 5.3387 3.1863
BTBR T+ Itpr3tf/J f 1.61 0.5474 2.6862 0.5338
BTBR T+ Itpr3tf/J m 1.9957 0.5852 3.1462 0.8452
BUB/BnJ f 2.57 0.6321 3.8127 1.3273
BUB/BnJ m 1.0489 0.5161 2.0636 0.0342
C3H/HeJ f 2.2575 0.5474 3.3337 1.1813
C3H/HeJ m 2.4575 0.5474 3.5337 1.3813
C57BL/10J f 5.3387 0.5474 6.415 4.2625
C57BL/10J m 5.0371 0.5852 6.1877 3.8866
C57BL/6J f 4.04 0.5474 5.1162 2.9638
C57BL/6J m 3.705 0.5474 4.7812 2.6288
C57BLKS/J f 4.8088 0.5474 5.885 3.7325
C57BLKS/J m 6.1187 0.5474 7.195 5.0425
C57BR/cdJ f 2.6325 0.5474 3.7087 1.5563
C57BR/cdJ m 3.3388 0.5474 4.415 2.2625
C57L/J f 2.1257 0.5852 3.2762 0.9752
C57L/J m 3.245 0.5474 4.3212 2.1688
CBA/J f 2.3963 0.5474 3.4725 1.32
CBA/J m 2.0637 0.5474 3.14 0.9875
DBA/2J f 3.8467 0.6321 5.0894 2.604
DBA/2J m 1.1943 0.5852 2.3448 0.0438
FVB/NJ f 2.5412 0.5474 3.6175 1.465
FVB/NJ m 4.05 0.5474 5.1262 2.9738
KK/HlJ f 3.5438 0.5474 4.62 2.4675
KK/HlJ m 7.1213 0.5474 8.1975 6.045
LP/J f 3.4786 0.5852 4.6291 2.328
LP/J m 4.9075 0.5474 5.9837 3.8313
MOLF/EiJ f 3.6571 0.5852 4.8077 2.5066
MOLF/EiJ m 3.8233 0.5161 4.838 2.8087
MRL/MpJ f 5.4412 0.5474 6.5175 4.365
MRL/MpJ m 4.875 0.5474 5.9512 3.7988
NON/ShiLtJ f 2.4537 0.5474 3.53 1.3775
NON/ShiLtJ m 3.2317 0.6321 4.4744 1.989
NZO/HlLtJ f 3.2317 0.6321 4.4744 1.989
NZO/HlLtJ m 1.7543 0.5852 2.9048 0.6038
NZW/LacJ f 1.005 0.5474 2.0812 0.0
NZW/LacJ m 1.6662 0.5474 2.7425 0.59
P/J f 2.5362 0.5474 3.6125 1.46
P/J m 1.91 0.5852 3.0605 0.7595
PL/J f 3.2329 0.5852 4.3834 2.0823
PL/J m 5.3717 0.6321 6.6144 4.129
PWD/PhJ f 5.0413 0.5474 6.1175 3.965
PWD/PhJ m 2.875 0.5474 3.9512 1.7988
RIIIS/J f 1.1137 0.5474 2.19 0.0375
RIIIS/J m 1.5837 0.5474 2.66 0.5075
SJL/J f 4.475 0.5474 5.5512 3.3988
SJL/J m 3.2767 0.5161 4.2913 2.262
SM/J f 0.9538 0.5474 2.03 0.0
SM/J m 1.1388 0.5474 2.215 0.0625
SWR/J f 3.5857 0.5852 4.7362 2.4352
SWR/J m 2.6186 0.5852 3.7691 1.468
WSB/EiJ f 4.5525 0.5474 5.6287 3.4763
WSB/EiJ m 5.3837 0.5474 6.46 4.3075


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 7.295 0.3871 8.056 6.534
A/J both 2.0594 0.3871 2.8204 1.2984
BALB/cByJ both 4.2794 0.3871 5.0404 3.5184
BTBR T+ Itpr3tf/J both 1.8029 0.4006 2.5906 1.0151
BUB/BnJ both 1.8094 0.408 2.6116 1.0073
C3H/HeJ both 2.3575 0.3871 3.1185 1.5965
C57BL/10J both 5.1879 0.4006 5.9757 4.4002
C57BL/6J both 3.8725 0.3871 4.6335 3.1115
C57BLKS/J both 5.4637 0.3871 6.2247 4.7028
C57BR/cdJ both 2.9856 0.3871 3.7466 2.2246
C57L/J both 2.6854 0.4006 3.4731 1.8976
CBA/J both 2.23 0.3871 2.991 1.469
DBA/2J both 2.5205 0.4307 3.3672 1.6737
FVB/NJ both 3.2956 0.3871 4.0566 2.5346
KK/HlJ both 5.3325 0.3871 6.0935 4.5715
LP/J both 4.193 0.4006 4.9807 3.4053
MOLF/EiJ both 3.7402 0.3901 4.5073 2.9732
MRL/MpJ both 5.1581 0.3871 5.9191 4.3971
NON/ShiLtJ both 2.8427 0.4181 3.6647 2.0207
NZO/HlLtJ both 2.493 0.4307 3.3397 1.6462
NZW/LacJ both 1.3356 0.3871 2.0966 0.5746
P/J both 2.2231 0.4006 3.0108 1.4354
PL/J both 4.3023 0.4307 5.149 3.4555
PWD/PhJ both 3.9581 0.3871 4.7191 3.1971
RIIIS/J both 1.3487 0.3871 2.1097 0.5878
SJL/J both 3.8758 0.3762 4.6154 3.1363
SM/J both 1.0463 0.3871 1.8072 0.2853
SWR/J both 3.1021 0.4138 3.9157 2.2886
WSB/EiJ both 4.9681 0.3871 5.7291 4.2071




  GWAS USING LINEAR MIXED MODELS