MPD: Project measure / variable: Petkova1 NEUT

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Petkova1 - neutrophil differential (NEUT; percentage of total WBC) at age 12mo

Measure Summary	Female	Male
Number of strains tested	30 strains	30 strains
Mean of the strain means	18.6 %	21.4 %
Median of the strain means	13.9 %	20.5 %
SD of the strain means	± 11.9	± 10.6
Coefficient of variation (CV)	0.639	0.497
Min–max range of strain means	5.48 – 60.2 %	9.36 – 43.4 %
Mean sample size per strain	7.6 mice	7.7 mice

ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p value (Pr>F)
sex	1	477.8822	477.8822	6.0636	0.0142
strain	28	46424.2122	1658.0076	21.0377	< 0.0001
sex:strain	28	9780.8469	349.316	4.4323	< 0.0001
Residuals	388	30578.7536	78.8112

Q-Q normality assessment based on residuals

STRAIN MEANS (UNADJUSTED)

Strain	Sex	Mean	SD	N mice	SEM	CV	Min, Max	Z score
129S1/SvImJ	f	15.6	3.25	8	1.15	0.209	11.6, 22.3	-0.25
129S1/SvImJ	m	42.7	14.2	8	5.03	0.333	25.0, 68.7	2.01
A/J	f	23.1	7.58	8	2.68	0.329	14.8, 34.4	0.38
A/J	m	20.4	9.07	8	3.21	0.444	12.6, 39.9	-0.09
AKR/J	m	26.7	8.07	5	3.61	0.302	19.0, 36.3	0.5
BALB/cByJ	f	11.5	4.84	8	1.71	0.422	4.58, 19.8	-0.6
BALB/cByJ	m	15.7	5.85	8	2.07	0.373	9.52, 28.3	-0.54
BTBR T⁺ Itpr3^tf/J	f	11.9	2.31	8	0.817	0.194	7.5, 14.1	-0.56
BTBR T⁺ Itpr3^tf/J	m	15.3	4.75	7	1.8	0.311	9.85, 24.9	-0.57
BUB/BnJ	f	11.4	6.49	6	2.65	0.568	4.29, 20.3	-0.61
BUB/BnJ	m	10.5	3.04	9	1.01	0.29	7.19, 17.4	-1.02
C3H/HeJ	f	60.2	11.6	8	4.1	0.193	33.4, 70.0	3.49
C3H/HeJ	m	36.1	10.3	8	3.63	0.284	16.0, 44.6	1.38
C57BL/10J	f	13.5	6.23	8	2.2	0.462	7.97, 26.1	-0.43
C57BL/10J	m	9.36	5.71	7	2.16	0.61	4.06, 21.4	-1.13
C57BL/6J	f	16.8	8.97	8	3.17	0.534	7.64, 35.8	-0.15
C57BL/6J	m	12.2	3.67	8	1.3	0.3	8.17, 17.9	-0.86
C57BLKS/J	f	10.3	8.31	8	2.94	0.805	3.76, 26.8	-0.7
C57BLKS/J	m	9.7	2.57	8	0.909	0.265	6.11, 13.1	-1.1
C57BR/cdJ	f	13.7	3.74	8	1.32	0.273	7.18, 18.5	-0.41
C57BR/cdJ	m	10.6	3.29	8	1.16	0.311	4.96, 14.3	-1.02
C57L/J	f	13.1	5.41	7	2.04	0.412	6.43, 22.8	-0.46
C57L/J	m	10.6	5.61	8	1.98	0.53	6.37, 23.6	-1.02
CAST/EiJ	f	10.7	7.19	3	4.15	0.674	4.58, 18.6	-0.67
CBA/J	f	21.4	24.5	8	8.65	1.14	8.35, 81.4	0.23
CBA/J	m	22.9	8.23	8	2.91	0.36	12.8, 31.0	0.14
DBA/2J	f	32.5	17.1	6	6.96	0.525	15.3, 62.9	1.17
DBA/2J	m	31.5	12.3	7	4.64	0.39	23.2, 58.0	0.95
FVB/NJ	f	10.6	1.97	8	0.695	0.186	9.17, 15.2	-0.67
FVB/NJ	m	28.5	8.59	8	3.04	0.302	19.6, 43.0	0.67
KK/HlJ	f	35.6	6.04	8	2.14	0.17	23.9, 44.2	1.43
KK/HlJ	m	43.4	12.3	8	4.35	0.284	26.5, 62.4	2.07
LP/J	f	14.2	8.07	7	3.05	0.567	6.85, 30.8	-0.37
LP/J	m	16.4	7.44	8	2.63	0.455	6.98, 29.0	-0.47
MOLF/EiJ	f	7.54	1.89	7	0.714	0.251	4.86, 10.7	-0.93
MOLF/EiJ	m	20.6	14.8	9	4.94	0.719	2.35, 47.2	-0.07
MRL/MpJ	f	37.6	10.1	8	3.57	0.269	21.4, 55.3	1.6
MRL/MpJ	m	34.7	18.4	8	6.52	0.532	9.9, 59.9	1.25
NON/ShiLtJ	f	39.7	8.31	8	2.94	0.209	31.2, 58.0	1.77
NON/ShiLtJ	m	42.4	12.1	6	4.96	0.286	27.0, 55.6	1.98
NZO/HlLtJ	f	18.3	6.59	6	2.69	0.359	10.3, 28.9	-0.03
NZO/HlLtJ	m	21.1	9.79	7	3.7	0.464	8.0, 38.8	-0.03
NZW/LacJ	f	11.5	1.68	8	0.595	0.146	8.67, 13.3	-0.6
NZW/LacJ	m	24.2	8.06	8	2.85	0.333	16.4, 41.6	0.26
P/J	f	14.6	5.87	8	2.07	0.402	8.9, 23.4	-0.34
P/J	m	11.2	3.58	7	1.35	0.32	6.3, 16.8	-0.96
PL/J	f	21.4	7.34	7	2.77	0.343	11.1, 30.5	0.23
PL/J	m	27.6	5.57	6	2.27	0.202	22.4, 37.1	0.58
PWD/PhJ	f	24.7	15.3	8	5.4	0.619	13.1, 60.9	0.51
PWD/PhJ	m	16.0	5.12	8	1.81	0.319	8.33, 22.4	-0.51
RIIIS/J	f	8.46	4.34	8	1.53	0.512	3.73, 15.5	-0.85
RIIIS/J	m	11.0	7.91	8	2.8	0.716	5.14, 29.7	-0.98
SJL/J	f	5.48	3.13	8	1.11	0.571	1.57, 9.43	-1.1
SJL/J	m	22.0	6.49	9	2.16	0.295	11.5, 35.1	0.06
SM/J	f	13.6	3.3	8	1.17	0.243	10.1, 17.8	-0.42
SM/J	m	11.6	5.25	8	1.86	0.453	5.03, 21.3	-0.92
SWR/J	f	10.1	3.86	7	1.46	0.38	7.81, 18.8	-0.72
SWR/J	m	11.2	3.49	7	1.32	0.312	7.02, 17.7	-0.96
WSB/EiJ	f	19.4	12.2	8	4.31	0.63	6.46, 38.2	0.07
WSB/EiJ	m	25.5	13.4	8	4.75	0.528	11.6, 46.6	0.39

LEAST SQUARES MEANS (MODEL-ADJUSTED)

Strain	Sex	Mean	SEM	UpperCL	LowerCL
129S1/SvImJ	f	15.5875	3.1387	21.7585	9.4165
129S1/SvImJ	m	42.7375	3.1387	48.9085	36.5665
A/J	f	23.05	3.1387	29.221	16.879
A/J	m	20.4375	3.1387	26.6085	14.2665
BALB/cByJ	f	11.47	3.1387	17.641	5.299
BALB/cByJ	m	15.69	3.1387	21.861	9.519
BTBR T⁺ Itpr3^tf/J	f	11.9012	3.1387	18.0722	5.7303
BTBR T⁺ Itpr3^tf/J	m	15.2786	3.3554	21.8756	8.6815
BUB/BnJ	f	11.43	3.6243	18.5556	4.3044
BUB/BnJ	m	10.4978	2.9592	16.3158	4.6797
C3H/HeJ	f	60.225	3.1387	66.396	54.054
C3H/HeJ	m	36.0875	3.1387	42.2585	29.9165
C57BL/10J	f	13.4875	3.1387	19.6585	7.3165
C57BL/10J	m	9.3557	3.3554	15.9528	2.7587
C57BL/6J	f	16.7987	3.1387	22.9697	10.6278
C57BL/6J	m	12.2213	3.1387	18.3922	6.0503
C57BLKS/J	f	10.3263	3.1387	16.4972	4.1553
C57BLKS/J	m	9.6963	3.1387	15.8672	3.5253
C57BR/cdJ	f	13.7225	3.1387	19.8935	7.5515
C57BR/cdJ	m	10.6013	3.1387	16.7722	4.4303
C57L/J	f	13.1186	3.3554	19.7156	6.5215
C57L/J	m	10.5788	3.1387	16.7497	4.4078
CBA/J	f	21.4412	3.1387	27.6122	15.2703
CBA/J	m	22.8625	3.1387	29.0335	16.6915
DBA/2J	f	32.4667	3.6243	39.5923	25.341
DBA/2J	m	31.4714	3.3554	38.0685	24.8744
FVB/NJ	f	10.565	3.1387	16.736	4.394
FVB/NJ	m	28.4875	3.1387	34.6585	22.3165
KK/HlJ	f	35.65	3.1387	41.821	29.479
KK/HlJ	m	43.4375	3.1387	49.6085	37.2665
LP/J	f	14.24	3.3554	20.8371	7.6429
LP/J	m	16.3675	3.1387	22.5385	10.1965
MOLF/EiJ	f	7.5386	3.3554	14.1356	0.9415
MOLF/EiJ	m	20.6167	2.9592	26.4347	14.7986
MRL/MpJ	f	37.55	3.1387	43.721	31.379
MRL/MpJ	m	34.6625	3.1387	40.8335	28.4915
NON/ShiLtJ	f	39.675	3.1387	45.846	33.504
NON/ShiLtJ	m	42.4	3.6243	49.5256	35.2744
NZO/HlLtJ	f	18.3333	3.6243	25.459	11.2077
NZO/HlLtJ	m	21.1143	3.3554	27.7113	14.5172
NZW/LacJ	f	11.4988	3.1387	17.6697	5.3278
NZW/LacJ	m	24.2125	3.1387	30.3835	18.0415
P/J	f	14.6	3.1387	20.771	8.429
P/J	m	11.1771	3.3554	17.7742	4.5801
PL/J	f	21.4286	3.3554	28.0256	14.8315
PL/J	m	27.6167	3.6243	34.7423	20.491
PWD/PhJ	f	24.675	3.1387	30.846	18.504
PWD/PhJ	m	16.04	3.1387	22.211	9.869
RIIIS/J	f	8.4613	3.1387	14.6322	2.2903
RIIIS/J	m	11.0463	3.1387	17.2172	4.8753
SJL/J	f	5.4788	3.1387	11.6497	0.0
SJL/J	m	22.0111	2.9592	27.8292	16.1931
SM/J	f	13.575	3.1387	19.746	7.404
SM/J	m	11.5925	3.1387	17.7635	5.4215
SWR/J	f	10.1443	3.3554	16.7413	3.5472
SWR/J	m	11.1914	3.3554	17.7885	4.5944
WSB/EiJ	f	19.3688	3.1387	25.5397	13.1978
WSB/EiJ	m	25.475	3.1387	31.646	19.304

LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED

Strain	Sex	Mean	SEM	UpperCL	LowerCL
129S1/SvImJ	both	29.1625	2.2194	33.526	24.799
A/J	both	21.7437	2.2194	26.1073	17.3802
BALB/cByJ	both	13.58	2.2194	17.9435	9.2165
BTBR T⁺ Itpr3^tf/J	both	13.5899	2.2973	18.1066	9.0732
BUB/BnJ	both	10.9639	2.3394	15.5635	6.3643
C3H/HeJ	both	48.1562	2.2194	52.5198	43.7927
C57BL/10J	both	11.4216	2.2973	15.9383	6.9049
C57BL/6J	both	14.51	2.2194	18.8735	10.1465
C57BLKS/J	both	10.0113	2.2194	14.3748	5.6477
C57BR/cdJ	both	12.1619	2.2194	16.5254	7.7983
C57L/J	both	11.8487	2.2973	16.3654	7.332
CBA/J	both	22.1519	2.2194	26.5154	17.7883
DBA/2J	both	31.969	2.4695	36.8243	27.1137
FVB/NJ	both	19.5263	2.2194	23.8898	15.1627
KK/HlJ	both	39.5438	2.2194	43.9073	35.1802
LP/J	both	15.3038	2.2973	19.8204	10.7871
MOLF/EiJ	both	14.0776	2.2369	18.4757	9.6796
MRL/MpJ	both	36.1062	2.2194	40.4698	31.7427
NON/ShiLtJ	both	41.0375	2.3972	45.7507	36.3243
NZO/HlLtJ	both	19.7238	2.4695	24.5791	14.8685
NZW/LacJ	both	17.8556	2.2194	22.2192	13.4921
P/J	both	12.8886	2.2973	17.4053	8.3719
PL/J	both	24.5226	2.4695	29.3779	19.6673
PWD/PhJ	both	20.3575	2.2194	24.721	15.994
RIIIS/J	both	9.7538	2.2194	14.1173	5.3902
SJL/J	both	13.7449	2.1569	17.9855	9.5043
SM/J	both	12.5838	2.2194	16.9473	8.2202
SWR/J	both	10.6679	2.3726	15.3327	6.003
WSB/EiJ	both	22.4219	2.2194	26.7854	18.0583

INDIVIDUAL ANIMAL VALUES

Click here to view individual animal values

GWAS USING LINEAR MIXED MODELS

ID, description, units	MPD:24212 NEUT_M12 neutrophil differential (NEUT; percentage of total WBC) [%] at age 12mo
Data set, strains	Petkova1 inbred 31 strains sex: both age: 52wks
Procedure	immune cell quantification
Ontology mappings	MA:0000059 blood MP:0012440 abnormal neutrophil cell number VT:0000222 neutrophil quantity