Project measure / variable:   Eumorphia1   LDH

ID, description, units MPD:23909   LDH   lactate dehydrogenase (plasma LDH)   [IU/L]  
Data set, strains Eumorphia1   inbred   4 strains     sex: both     age: 12wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Eumorphia1 - lactate dehydrogenase (plasma LDH)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested4 strains4 strains
Mean of the strain means552   IU/L 508   IU/L
Median of the strain means534   IU/L 550   IU/L
SD of the strain means± 248 ± 177
Coefficient of variation (CV)0.449 0.349
Min–max range of strain means268   –   873   IU/L 259   –   675   IU/L
Mean sample size per strain20.0   mice 19.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 66931.789 66931.789 0.5106 0.476
strain 3 4475772.1612 1491924.0537 11.3811 < 0.0001
sex:strain 3 1027501.3515 342500.4505 2.6128 0.0535
Residuals 150 19663116.5526 131087.4437


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S2/SvPas f 268.0 144.0   20 32.3 0.539 161.0, 820.0 -1.15
129S2/SvPas m 259.0 99.9   19 22.9 0.385 132.0, 486.0 -1.41
BALB/cJ f 873.0 632.0   20 141.0 0.724 206.0, 2982.0 1.29
BALB/cJ m 571.0 325.0   19 74.5 0.569 205.0, 1272.0 0.35
C3HeB/FeJ f 536.0 296.0   20 66.1 0.552 256.0, 1482.0 -0.07
C3HeB/FeJ m 528.0 426.0   20 95.4 0.807 243.0, 2067.0 0.11
C57BL/6J f 532.0 174.0   20 38.9 0.327 233.0, 1006.0 -0.08
C57BL/6J m 675.0 454.0   20 101.0 0.672 140.0, 1588.0 0.94


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S2/SvPas f 267.8 80.9591 427.7675 107.8325
129S2/SvPas m 259.4211 83.0623 423.5442 95.2979
BALB/cJ f 872.8 80.9591 1032.7675 712.8325
BALB/cJ m 570.6316 83.0623 734.7547 406.5084
C3HeB/FeJ f 535.75 80.9591 695.7175 375.7825
C3HeB/FeJ m 528.3 80.9591 688.2675 368.3325
C57BL/6J f 531.55 80.9591 691.5175 371.5825
C57BL/6J m 675.3 80.9591 835.2675 515.3325


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S2/SvPas both 263.6105 57.9951 378.2033 149.0178
BALB/cJ both 721.7158 57.9951 836.3086 607.123
C3HeB/FeJ both 532.025 57.2467 645.1391 418.9109
C57BL/6J both 603.425 57.2467 716.5391 490.3109




GWAS analysis not available: SNP data is not available for enough strains (at least 4)