Project measure / variable:   Eumorphia1   CK

ID, description, units MPD:23904   CK   creatine kinase (plasma CK)   [IU/L]  
Data set, strains Eumorphia1   inbred   4 strains     sex: both     age: 12wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Eumorphia1 - creatine kinase (plasma CK)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested4 strains4 strains
Mean of the strain means546   IU/L 652   IU/L
Median of the strain means461   IU/L 591   IU/L
SD of the strain means± 336 ± 394
Coefficient of variation (CV)0.616 0.605
Min–max range of strain means249   –   1013   IU/L 308   –   1119   IU/L
Mean sample size per strain33.2   mice 33.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 869542.1802 869542.1802 0.9098 0.3411
strain 3 21991194.4046 7330398.1349 7.6698 0.0001
sex:strain 3 4911231.4747 1637077.1582 1.7129 0.1647
Residuals 260 248493967.7315 955746.0297


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S2/SvPas f 249.0 409.0   35 69.2 1.65 12.0, 1898.0 -0.88
129S2/SvPas m 308.0 389.0   34 66.8 1.26 8.0, 1693.0 -0.87
BALB/cJ f 1013.0 1344.0   32 238.0 1.33 14.0, 4640.0 1.39
BALB/cJ m 839.0 1216.0   34 209.0 1.45 36.0, 4823.0 0.47
C3HeB/FeJ f 364.0 670.0   35 113.0 1.84 30.0, 3700.0 -0.54
C3HeB/FeJ m 343.0 535.0   34 91.8 1.56 18.0, 1984.0 -0.78
C57BL/6J f 558.0 567.0   31 102.0 1.02 42.0, 1712.0 0.04
C57BL/6J m 1119.0 1756.0   33 306.0 1.57 14.0, 8530.0 1.18


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S2/SvPas f 248.5429 165.2484 573.9384 0.0
129S2/SvPas m 307.8824 167.6609 638.0285 0.0
BALB/cJ f 1013.4062 172.8209 1353.7131 673.0994
BALB/cJ m 839.2941 167.6609 1169.4402 509.148
C3HeB/FeJ f 363.5429 165.2484 688.9384 38.1473
C3HeB/FeJ m 343.3235 167.6609 673.4696 13.1774
C57BL/6J f 558.3548 175.5862 904.1069 212.6028
C57BL/6J m 1119.2121 170.1823 1454.3231 784.1011


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S2/SvPas both 278.2126 117.7043 509.9877 46.4375
BALB/cJ both 926.3502 120.3923 1163.4183 689.2821
C3HeB/FeJ both 353.4332 117.7043 585.2083 121.6581
C57BL/6J both 838.7835 122.2625 1079.5343 598.0326




GWAS analysis not available: SNP data is not available for enough strains (at least 4)