Project measure / variable:   Eumorphia1   AST

ID, description, units MPD:23903   AST   aspartate transaminase (plasma AST)   [IU/L]  
Data set, strains Eumorphia1   inbred   4 strains     sex: both     age: 12wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Eumorphia1 - aspartate transaminase (plasma AST)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested4 strains4 strains
Mean of the strain means140   IU/L 126   IU/L
Median of the strain means126   IU/L 116   IU/L
SD of the strain means± 73.4 ± 53.3
Coefficient of variation (CV)0.525 0.424
Min–max range of strain means71.7   –   236   IU/L 76.7   –   194   IU/L
Mean sample size per strain20.0   mice 19.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 7827.4821 7827.4821 0.7757 0.3799
strain 3 395751.4461 131917.1487 13.0724 < 0.0001
sex:strain 3 93131.2903 31043.7634 3.0763 0.0295
Residuals 150 1513693.7816 10091.2919


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S2/SvPas f 71.7 30.4   20 6.79 0.424 48.0, 171.0 -0.93
129S2/SvPas m 76.7 22.2   19 5.08 0.289 44.0, 142.0 -0.92
BALB/cJ f 236.0 183.0   20 41.0 0.779 47.0, 725.0 1.31
BALB/cJ m 141.0 90.3   19 20.7 0.641 57.0, 328.0 0.29
C3HeB/FeJ f 95.2 57.0   20 12.7 0.598 52.0, 276.0 -0.61
C3HeB/FeJ m 90.7 64.4   20 14.4 0.71 38.0, 276.0 -0.65
C57BL/6J f 157.0 79.6   20 17.8 0.506 55.0, 347.0 0.23
C57BL/6J m 194.0 152.0   20 34.0 0.787 37.0, 560.0 1.28


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S2/SvPas f 71.65 22.4625 116.0338 27.2662
129S2/SvPas m 76.6842 23.0461 122.221 31.1474
BALB/cJ f 235.55 22.4625 279.9338 191.1662
BALB/cJ m 140.8421 23.0461 186.3789 95.3053
C3HeB/FeJ f 95.25 22.4625 139.6338 50.8662
C3HeB/FeJ m 90.65 22.4625 135.0338 46.2662
C57BL/6J f 157.35 22.4625 201.7338 112.9662
C57BL/6J m 193.6 22.4625 237.9838 149.2162


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S2/SvPas both 74.1671 16.091 105.9615 42.3727
BALB/cJ both 188.1961 16.091 219.9904 156.4017
C3HeB/FeJ both 92.95 15.8834 124.3341 61.5659
C57BL/6J both 175.475 15.8834 206.8591 144.0909




GWAS analysis not available: SNP data is not available for enough strains (at least 4)