Project measure / variable:   Eumorphia1   ALT

ID, description, units MPD:23901   ALT   alanine transaminase (plasma ALT)   [IU/L]  
Data set, strains Eumorphia1   inbred   4 strains     sex: both     age: 12wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Eumorphia1 - alanine transaminase (plasma ALT)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested4 strains4 strains
Mean of the strain means47.9   IU/L 42.2   IU/L
Median of the strain means38.1   IU/L 39.4   IU/L
SD of the strain means± 28.3 ± 14.8
Coefficient of variation (CV)0.590 0.351
Min–max range of strain means26.4   –   89.0   IU/L 27.6   –   62.6   IU/L
Mean sample size per strain20.0   mice 19.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1309.6928 1309.6928 0.9955 0.32
strain 3 54790.1496 18263.3832 13.8817 < 0.0001
sex:strain 3 5718.1286 1906.0429 1.4488 0.231
Residuals 150 197346.2632 1315.6418


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S2/SvPas f 26.4 17.3   20 3.87 0.657 14.0, 93.0 -0.76
129S2/SvPas m 27.6 11.5   19 2.63 0.416 13.0, 56.0 -0.99
BALB/cJ f 89.0 75.3   20 16.8 0.847 22.0, 344.0 1.45
BALB/cJ m 62.6 42.0   19 9.63 0.671 21.0, 187.0 1.37
C3HeB/FeJ f 32.8 17.3   20 3.86 0.526 19.0, 94.0 -0.53
C3HeB/FeJ m 36.6 28.0   20 6.25 0.764 21.0, 144.0 -0.38
C57BL/6J f 43.5 32.4   20 7.25 0.744 18.0, 155.0 -0.16
C57BL/6J m 42.1 22.1   20 4.95 0.525 10.0, 84.0 -0.01


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S2/SvPas f 26.35 8.1106 42.3758 10.3242
129S2/SvPas m 27.5789 8.3213 44.0211 11.1368
BALB/cJ f 88.95 8.1106 104.9758 72.9242
BALB/cJ m 62.5789 8.3213 79.0211 46.1368
C3HeB/FeJ f 32.8 8.1106 48.8258 16.7742
C3HeB/FeJ m 36.6 8.1106 52.6258 20.5742
C57BL/6J f 43.55 8.1106 59.5758 27.5242
C57BL/6J m 42.15 8.1106 58.1758 26.1242


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S2/SvPas both 26.9645 5.81 38.4446 15.4844
BALB/cJ both 75.7645 5.81 87.2446 64.2844
C3HeB/FeJ both 34.7 5.7351 46.032 23.368
C57BL/6J both 42.85 5.7351 54.182 31.518




GWAS analysis not available: SNP data is not available for enough strains (at least 4)