Project measure / variable:   Lake1   bp_sd

ID, description, units MPD:19954   bp_sd   systolic blood pressure variability across tests (local parameter)   [mmHg]  
Data set, strains Lake1   B6.A consomic w/par   23 strains     sex: both     age: 10wks
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Lake1 - systolic blood pressure variability across tests (local parameter)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested23 strains23 strains
Mean of the strain means17.4   mmHg 17.9   mmHg
Median of the strain means16.2   mmHg 17.0   mmHg
SD of the strain means± 4.79 ± 4.13
Coefficient of variation (CV)0.275 0.231
Min–max range of strain means11.0   –   34.7   mmHg 12.8   –   32.2   mmHg
Mean sample size per strain8.0   mice 8.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 18.6437 18.6437 0.4971 0.4813
strain 22 6009.6443 273.1656 7.2839 < 0.0001
sex:strain 22 1059.6842 48.1675 1.2844 0.1784
Residuals 325 12188.3912 37.5027


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 34.7 6.08   8 2.15 0.175 27.2, 45.1 3.62
A/J m 32.2 10.7   8 3.77 0.331 16.9, 46.9 3.47
B6.A-Chr1 f 15.6 6.05   8 2.14 0.387 6.44, 25.5 -0.37
B6.A-Chr1 m 15.4 8.08   8 2.86 0.523 6.79, 27.9 -0.59
B6.A-Chr10 f 14.0 5.88   9 1.96 0.421 8.85, 28.0 -0.71
B6.A-Chr10 m 15.7 5.72   8 2.02 0.363 5.58, 23.6 -0.52
B6.A-Chr11 f 15.7 6.43   8 2.27 0.41 7.43, 29.4 -0.35
B6.A-Chr11 m 18.4 10.7   8 3.78 0.581 9.76, 40.3 0.13
B6.A-Chr12 f 17.1 2.84   8 1.0 0.166 12.9, 19.9 -0.06
B6.A-Chr12 m 18.9 5.64   8 1.99 0.299 13.5, 28.3 0.25
B6.A-Chr13 f 17.6 5.98   8 2.12 0.34 9.03, 26.1 0.05
B6.A-Chr13 m 17.0 7.69   8 2.72 0.453 8.2, 32.1 -0.21
B6.A-Chr14 f 20.7 7.53   8 2.66 0.364 10.6, 30.5 0.69
B6.A-Chr14 m 16.2 3.74   8 1.32 0.23 12.3, 22.7 -0.4
B6.A-Chr15 f 14.8 4.42   9 1.47 0.298 7.81, 22.4 -0.54
B6.A-Chr15 m 16.0 4.75   8 1.68 0.296 8.56, 21.9 -0.45
B6.A-Chr16 f 16.6 7.95   6 3.25 0.479 7.67, 27.4 -0.16
B6.A-Chr16 m 15.4 2.4   8 0.847 0.155 12.6, 19.3 -0.59
B6.A-Chr17 f 15.1 4.16   8 1.47 0.275 9.61, 21.7 -0.48
B6.A-Chr17 m 17.9 4.85   8 1.72 0.271 10.4, 26.6 0.01
B6.A-Chr18 f 15.3 4.38   8 1.55 0.287 9.84, 21.9 -0.44
B6.A-Chr18 m 18.7 6.75   8 2.39 0.362 9.59, 31.9 0.2
B6.A-Chr19 f 21.9 7.98   8 2.82 0.364 12.1, 34.2 0.94
B6.A-Chr19 m 24.6 6.67   8 2.36 0.271 15.1, 33.2 1.63
B6.A-Chr2 f 16.2 5.81   8 2.05 0.359 9.22, 28.3 -0.25
B6.A-Chr2 m 21.7 6.86   8 2.43 0.317 12.8, 30.4 0.93
B6.A-Chr3 f 19.9 5.76   8 2.04 0.29 15.1, 31.9 0.53
B6.A-Chr3 m 13.9 4.36   8 1.54 0.313 9.46, 22.9 -0.96
B6.A-Chr4 f 11.0 7.64   8 2.7 0.697 4.63, 28.3 -1.33
B6.A-Chr4 m 16.4 4.27   8 1.51 0.26 9.88, 23.1 -0.35
B6.A-Chr5 f 20.7 5.49   8 1.94 0.266 13.4, 29.5 0.69
B6.A-Chr5 m 16.9 4.9   8 1.73 0.289 9.25, 23.0 -0.23
B6.A-Chr6 f 19.6 8.62   7 3.26 0.44 8.27, 27.6 0.46
B6.A-Chr6 m 12.8 6.03   8 2.13 0.47 7.92, 26.3 -1.22
B6.A-Chr7 f 12.6 3.78   8 1.34 0.3 6.25, 17.8 -1.0
B6.A-Chr7 m 17.3 4.04   8 1.43 0.234 13.7, 25.6 -0.13
B6.A-Chr8 f 16.2 5.28   8 1.87 0.325 9.34, 23.2 -0.25
B6.A-Chr8 m 14.5 4.09   12 1.18 0.282 8.95, 23.6 -0.81
B6.A-Chr9 f 21.5 9.34   8 3.3 0.434 9.77, 34.7 0.86
B6.A-Chr9 m 21.7 4.27   8 1.51 0.197 15.3, 27.1 0.93
B6.A-ChrX f 14.0 4.39   8 1.55 0.313 9.26, 21.4 -0.71
B6.A-ChrX m 14.3 7.27   8 2.57 0.509 9.5, 30.7 -0.86
B6.A-ChrY f 13.0 4.68   8 1.65 0.359 7.3, 20.6 -0.92
B6.A-ChrY m 17.6 5.85   8 2.07 0.332 11.0, 29.4 -0.06
C57BL/6J f 16.0 3.56   8 1.26 0.222 12.1, 20.7 -0.29
C57BL/6J m 17.2 7.12   8 2.52 0.413 6.89, 30.7 -0.16


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 34.6875 2.1651 38.947 30.428
A/J m 32.1625 2.1651 36.422 27.903
B6.A-Chr1 f 15.63 2.1651 19.8895 11.3705
B6.A-Chr1 m 15.4475 2.1651 19.707 11.188
B6.A-Chr10 f 13.9578 2.0413 17.9736 9.9419
B6.A-Chr10 m 15.7475 2.1651 20.007 11.488
B6.A-Chr11 f 15.6912 2.1651 19.9507 11.4318
B6.A-Chr11 m 18.42 2.1651 22.6795 14.1605
B6.A-Chr12 f 17.075 2.1651 21.3345 12.8155
B6.A-Chr12 m 18.8875 2.1651 23.147 14.628
B6.A-Chr13 f 17.6037 2.1651 21.8632 13.3443
B6.A-Chr13 m 17.0 2.1651 21.2595 12.7405
B6.A-Chr14 f 20.7125 2.1651 24.972 16.453
B6.A-Chr14 m 16.2125 2.1651 20.472 11.953
B6.A-Chr15 f 14.8256 2.0413 18.8414 10.8097
B6.A-Chr15 m 16.0075 2.1651 20.267 11.748
B6.A-Chr16 f 16.5917 2.5001 21.5101 11.6733
B6.A-Chr16 m 15.425 2.1651 19.6845 11.1655
B6.A-Chr17 f 15.1075 2.1651 19.367 10.848
B6.A-Chr17 m 17.9125 2.1651 22.172 13.653
B6.A-Chr18 f 15.255 2.1651 19.5145 10.9955
B6.A-Chr18 m 18.6612 2.1651 22.9207 14.4018
B6.A-Chr19 f 21.9125 2.1651 26.172 17.653
B6.A-Chr19 m 24.575 2.1651 28.8345 20.3155
B6.A-Chr2 f 16.19 2.1651 20.4495 11.9305
B6.A-Chr2 m 21.6625 2.1651 25.922 17.403
B6.A-Chr3 f 19.8875 2.1651 24.147 15.628
B6.A-Chr3 m 13.9075 2.1651 18.167 9.648
B6.A-Chr4 f 10.96 2.1651 15.2195 6.7005
B6.A-Chr4 m 16.435 2.1651 20.6945 12.1755
B6.A-Chr5 f 20.6625 2.1651 24.922 16.403
B6.A-Chr5 m 16.9312 2.1651 21.1907 12.6718
B6.A-Chr6 f 19.5957 2.3146 24.1493 15.0422
B6.A-Chr6 m 12.8312 2.1651 17.0907 8.5718
B6.A-Chr7 f 12.6112 2.1651 16.8707 8.3518
B6.A-Chr7 m 17.3 2.1651 21.5595 13.0405
B6.A-Chr8 f 16.23 2.1651 20.4895 11.9705
B6.A-Chr8 m 14.51 1.7678 17.9878 11.0322
B6.A-Chr9 f 21.5212 2.1651 25.7807 17.2618
B6.A-Chr9 m 21.7375 2.1651 25.997 17.478
B6.A-ChrX f 14.02 2.1651 18.2795 9.7605
B6.A-ChrX m 14.2625 2.1651 18.522 10.003
B6.A-ChrY f 13.0337 2.1651 17.2932 8.7743
B6.A-ChrY m 17.6 2.1651 21.8595 13.3405
C57BL/6J f 16.0 2.1651 20.2595 11.7405
C57BL/6J m 17.2487 2.1651 21.5082 12.9893


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 33.425 1.531 36.4369 30.4131
B6.A-Chr1 both 15.5387 1.531 18.5506 12.5269
B6.A-Chr10 both 14.8526 1.4879 17.7797 11.9256
B6.A-Chr11 both 17.0556 1.531 20.0675 14.0437
B6.A-Chr12 both 17.9812 1.531 20.9931 14.9694
B6.A-Chr13 both 17.3019 1.531 20.3138 14.29
B6.A-Chr14 both 18.4625 1.531 21.4744 15.4506
B6.A-Chr15 both 15.4165 1.4879 18.3436 12.4895
B6.A-Chr16 both 16.0083 1.6537 19.2616 12.7551
B6.A-Chr17 both 16.51 1.531 19.5219 13.4981
B6.A-Chr18 both 16.9581 1.531 19.97 13.9462
B6.A-Chr19 both 23.2437 1.531 26.2556 20.2319
B6.A-Chr2 both 18.9262 1.531 21.9381 15.9144
B6.A-Chr3 both 16.8975 1.531 19.9094 13.8856
B6.A-Chr4 both 13.6975 1.531 16.7094 10.6856
B6.A-Chr5 both 18.7969 1.531 21.8088 15.785
B6.A-Chr6 both 16.2135 1.5847 19.3311 13.0959
B6.A-Chr7 both 14.9556 1.531 17.9675 11.9437
B6.A-Chr8 both 15.37 1.3976 18.1195 12.6205
B6.A-Chr9 both 21.6294 1.531 24.6413 18.6175
B6.A-ChrX both 14.1412 1.531 17.1531 11.1294
B6.A-ChrY both 15.3169 1.531 18.3288 12.305
C57BL/6J both 16.6244 1.531 19.6363 13.6125




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA