Project measure / variable:   Lake1   bp

ID, description, units MPD:19953   bp   systolic blood pressure   [mmHg]  
Data set, strains Lake1   B6.A consomic w/par   23 strains     sex: both     age: 10wks
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  STRAIN COMPARISON PLOT
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Lake1 - systolic blood pressure



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested23 strains23 strains
Mean of the strain means116   mmHg 114   mmHg
Median of the strain means115   mmHg 113   mmHg
SD of the strain means± 7.99 ± 6.48
Coefficient of variation (CV)0.0689 0.0568
Min–max range of strain means94.6   –   131   mmHg 99.1   –   131   mmHg
Mean sample size per strain8.0   mice 8.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 315.7587 315.7587 2.327 0.1281
strain 22 11171.3642 507.7893 3.7421 < 0.0001
sex:strain 22 7301.1189 331.869 2.4457 0.0004
Residuals 325 44101.277 135.6962


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 94.6 12.7   8 4.5 0.134 73.7, 113.0 -2.67
A/J m 111.0 12.7   8 4.5 0.115 98.5, 135.0 -0.46
B6.A-Chr1 f 121.0 21.6   8 7.63 0.179 81.5, 149.0 0.63
B6.A-Chr1 m 112.0 5.35   8 1.89 0.0479 104.0, 119.0 -0.31
B6.A-Chr10 f 113.0 8.59   9 2.86 0.0757 101.0, 129.0 -0.37
B6.A-Chr10 m 109.0 5.92   8 2.09 0.0545 98.4, 115.0 -0.77
B6.A-Chr11 f 110.0 16.1   8 5.69 0.146 87.8, 128.0 -0.74
B6.A-Chr11 m 112.0 13.5   8 4.79 0.121 93.5, 135.0 -0.31
B6.A-Chr12 f 112.0 6.36   8 2.25 0.0567 103.0, 120.0 -0.49
B6.A-Chr12 m 115.0 7.31   8 2.58 0.0633 101.0, 126.0 0.15
B6.A-Chr13 f 122.0 8.43   8 2.98 0.069 113.0, 141.0 0.76
B6.A-Chr13 m 109.0 12.0   8 4.25 0.11 97.1, 131.0 -0.77
B6.A-Chr14 f 108.0 6.87   8 2.43 0.0636 95.2, 117.0 -0.99
B6.A-Chr14 m 108.0 13.9   8 4.9 0.128 78.0, 121.0 -0.93
B6.A-Chr15 f 118.0 9.5   9 3.17 0.0807 105.0, 136.0 0.26
B6.A-Chr15 m 113.0 11.9   8 4.21 0.106 90.7, 124.0 -0.16
B6.A-Chr16 f 111.0 11.8   6 4.82 0.106 97.2, 125.0 -0.62
B6.A-Chr16 m 109.0 14.0   8 4.96 0.128 87.5, 131.0 -0.77
B6.A-Chr17 f 117.0 5.1   8 1.8 0.0437 110.0, 124.0 0.13
B6.A-Chr17 m 116.0 16.6   8 5.86 0.143 90.7, 139.0 0.31
B6.A-Chr18 f 110.0 10.1   8 3.57 0.0919 96.7, 124.0 -0.74
B6.A-Chr18 m 111.0 17.9   8 6.32 0.161 74.5, 129.0 -0.46
B6.A-Chr19 f 123.0 15.4   8 5.45 0.125 103.0, 152.0 0.88
B6.A-Chr19 m 123.0 9.71   8 3.43 0.0788 109.0, 137.0 1.39
B6.A-Chr2 f 114.0 13.9   8 4.92 0.122 99.8, 132.0 -0.24
B6.A-Chr2 m 116.0 13.0   8 4.61 0.113 103.0, 137.0 0.31
B6.A-Chr3 f 129.0 11.5   8 4.07 0.0894 113.0, 148.0 1.64
B6.A-Chr3 m 99.1 5.42   8 1.92 0.0547 92.1, 106.0 -2.3
B6.A-Chr4 f 108.0 12.6   8 4.44 0.116 93.7, 134.0 -0.99
B6.A-Chr4 m 110.0 8.1   8 2.86 0.0736 97.1, 121.0 -0.62
B6.A-Chr5 f 115.0 6.41   8 2.27 0.0556 106.0, 128.0 -0.12
B6.A-Chr5 m 114.0 9.12   8 3.22 0.0797 99.6, 127.0 0.0
B6.A-Chr6 f 125.0 9.67   7 3.66 0.0776 112.0, 136.0 1.13
B6.A-Chr6 m 117.0 6.61   8 2.34 0.0563 110.0, 129.0 0.46
B6.A-Chr7 f 124.0 11.5   8 4.08 0.093 106.0, 138.0 1.01
B6.A-Chr7 m 122.0 7.78   8 2.75 0.0636 110.0, 133.0 1.23
B6.A-Chr8 f 111.0 10.5   8 3.72 0.0946 96.1, 127.0 -0.62
B6.A-Chr8 m 120.0 13.5   12 3.91 0.113 103.0, 142.0 0.93
B6.A-Chr9 f 118.0 17.5   8 6.19 0.148 96.5, 155.0 0.26
B6.A-Chr9 m 131.0 13.8   8 4.88 0.105 108.0, 152.0 2.62
B6.A-ChrX f 118.0 9.71   8 3.43 0.0824 106.0, 136.0 0.26
B6.A-ChrX m 113.0 14.6   8 5.16 0.129 88.5, 132.0 -0.16
B6.A-ChrY f 114.0 7.61   8 2.69 0.0666 105.0, 127.0 -0.24
B6.A-ChrY m 111.0 8.1   8 2.86 0.0729 98.6, 120.0 -0.46
C57BL/6J f 131.0 7.45   8 2.64 0.057 117.0, 140.0 1.89
C57BL/6J m 121.0 14.2   8 5.03 0.118 107.0, 142.0 1.08


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 94.575 4.1185 102.6773 86.4727
A/J m 110.6 4.1185 118.7023 102.4977
B6.A-Chr1 f 120.8125 4.1185 128.9148 112.7102
B6.A-Chr1 m 111.5 4.1185 119.6023 103.3977
B6.A-Chr10 f 113.4444 3.883 121.0833 105.8055
B6.A-Chr10 m 108.675 4.1185 116.7773 100.5727
B6.A-Chr11 f 110.2875 4.1185 118.3898 102.1852
B6.A-Chr11 m 111.9 4.1185 120.0023 103.7977
B6.A-Chr12 f 112.25 4.1185 120.3523 104.1477
B6.A-Chr12 m 115.375 4.1185 123.4773 107.2727
B6.A-Chr13 f 122.25 4.1185 130.3523 114.1477
B6.A-Chr13 m 109.4 4.1185 117.5023 101.2977
B6.A-Chr14 f 108.025 4.1185 116.1273 99.9227
B6.A-Chr14 m 108.0 4.1185 116.1023 99.8977
B6.A-Chr15 f 117.6667 3.883 125.3056 110.0278
B6.A-Chr15 m 112.7375 4.1185 120.8398 104.6352
B6.A-Chr16 f 111.2 4.7556 120.5557 101.8443
B6.A-Chr16 m 109.3125 4.1185 117.4148 101.2102
B6.A-Chr17 f 116.625 4.1185 124.7273 108.5227
B6.A-Chr17 m 116.3375 4.1185 124.4398 108.2352
B6.A-Chr18 f 109.775 4.1185 117.8773 101.6727
B6.A-Chr18 m 111.3125 4.1185 119.4148 103.2102
B6.A-Chr19 f 123.375 4.1185 131.4773 115.2727
B6.A-Chr19 m 123.25 4.1185 131.3523 115.1477
B6.A-Chr2 f 113.975 4.1185 122.0773 105.8727
B6.A-Chr2 m 115.625 4.1185 123.7273 107.5227
B6.A-Chr3 f 128.875 4.1185 136.9773 120.7727
B6.A-Chr3 m 99.0625 4.1185 107.1648 90.9602
B6.A-Chr4 f 108.5 4.1185 116.6023 100.3977
B6.A-Chr4 m 110.0125 4.1185 118.1148 101.9102
B6.A-Chr5 f 115.25 4.1185 123.3523 107.1477
B6.A-Chr5 m 114.45 4.1185 122.5523 106.3477
B6.A-Chr6 f 124.7143 4.4029 133.376 116.0526
B6.A-Chr6 m 117.25 4.1185 125.3523 109.1477
B6.A-Chr7 f 124.125 4.1185 132.2273 116.0227
B6.A-Chr7 m 122.375 4.1185 130.4773 114.2727
B6.A-Chr8 f 111.1375 4.1185 119.2398 103.0352
B6.A-Chr8 m 119.5 3.3627 126.1155 112.8845
B6.A-Chr9 f 118.1875 4.1185 126.2898 110.0852
B6.A-Chr9 m 131.0 4.1185 139.1023 122.8977
B6.A-ChrX f 117.75 4.1185 125.8523 109.6477
B6.A-ChrX m 113.3125 4.1185 121.4148 105.2102
B6.A-ChrY f 114.375 4.1185 122.4773 106.2727
B6.A-ChrY m 111.2 4.1185 119.3023 103.0977
C57BL/6J f 130.875 4.1185 138.9773 122.7727
C57BL/6J m 120.75 4.1185 128.8523 112.6477


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 102.5875 2.9122 108.3167 96.8583
B6.A-Chr1 both 116.1562 2.9122 121.8854 110.4271
B6.A-Chr10 both 111.0597 2.8302 116.6275 105.492
B6.A-Chr11 both 111.0938 2.9122 116.8229 105.3646
B6.A-Chr12 both 113.8125 2.9122 119.5417 108.0833
B6.A-Chr13 both 115.825 2.9122 121.5542 110.0958
B6.A-Chr14 both 108.0125 2.9122 113.7417 102.2833
B6.A-Chr15 both 115.2021 2.8302 120.7698 109.6343
B6.A-Chr16 both 110.2562 3.1456 116.4445 104.068
B6.A-Chr17 both 116.4812 2.9122 122.2104 110.7521
B6.A-Chr18 both 110.5438 2.9122 116.2729 104.8146
B6.A-Chr19 both 123.3125 2.9122 129.0417 117.5833
B6.A-Chr2 both 114.8 2.9122 120.5292 109.0708
B6.A-Chr3 both 113.9688 2.9122 119.6979 108.2396
B6.A-Chr4 both 109.2563 2.9122 114.9854 103.5271
B6.A-Chr5 both 114.85 2.9122 120.5792 109.1208
B6.A-Chr6 both 120.9821 3.0144 126.9124 115.0519
B6.A-Chr7 both 123.25 2.9122 128.9792 117.5208
B6.A-Chr8 both 115.3187 2.6585 120.5488 110.0887
B6.A-Chr9 both 124.5938 2.9122 130.3229 118.8646
B6.A-ChrX both 115.5312 2.9122 121.2604 109.8021
B6.A-ChrY both 112.7875 2.9122 118.5167 107.0583
C57BL/6J both 125.8125 2.9122 131.5417 120.0833




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA