Project measure / variable:   Threadgill1   liverwt_Rx300_24h

ID, description, units MPD:19463   liverwt_Rx300_24h   liver weight 24h after treatment   [g]  dose: 300 mg/kg  
acetaminophen study
Data set, strains Threadgill1   inbred w/CC7   37 strains     sex: m     age: 8-17wks
Procedure organ weights
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  STRAIN COMPARISON PLOT
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Threadgill1 - liver weight 24h after treatment dose: 300 mg/kg



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested37 strains
Mean of the strain means1.24   g
Median of the strain means1.26   g
SD of the strain means± 0.351
Coefficient of variation (CV)0.282
Min–max range of strain means0.547   –   1.92   g
Mean sample size per strain3.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 36 17.4074 0.4835 12.6196 < 0.0001
Residuals 106 4.0616 0.0383


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 1.0 0.0947   4 0.0473 0.0942 0.9, 1.13 -0.69
A/J m 0.997 0.221   4 0.11 0.221 0.69, 1.2 -0.7
AKR/J m 1.67 0.0944   6 0.0385 0.0566 1.56, 1.8 1.22
B6C3F1/J m 1.33 0.0577   3 0.0333 0.0433 1.3, 1.4 0.25
BALB/cByJ m 1.77 0.117   4 0.0587 0.0664 1.6, 1.87 1.5
BTBR T+ Itpr3tf/J m 1.8 0.271   4 0.135 0.15 1.6, 2.2 1.59
BUB/BnJ m 1.6 0.2   3 0.115 0.125 1.4, 1.8 1.02
C3H/HeJ m 1.3 0.229   4 0.114 0.176 1.1, 1.58 0.16
C57BL/10J m 1.31 0.131   4 0.0654 0.1 1.15, 1.47 0.19
C57BL/6J m 1.22 0.156   4 0.0782 0.128 1.07, 1.4 -0.07
C57BLKS/J m 1.27 0.169   4 0.0846 0.133 1.1, 1.43 0.08
C57BR/cdJ m 1.44 0.367   4 0.184 0.255 1.04, 1.91 0.56
C57L/J m 0.973 0.0987   3 0.057 0.101 0.86, 1.04 -0.77
CAST/EiJ m 0.547 0.139   4 0.0697 0.255 0.37, 0.7 -1.98
CBA/J m 1.52 0.164   4 0.0819 0.108 1.31, 1.7 0.79
CZECHII/EiJ m 0.857 0.214   3 0.123 0.249 0.7, 1.1 -1.1
DBA/2J m 1.26 0.115   6 0.0469 0.0911 1.1, 1.4 0.05
FVB/NJ m 1.44 0.335   4 0.167 0.233 1.1, 1.9 0.56
JF1/MsJ m 0.87 0.173   4 0.0863 0.198 0.71, 1.1 -1.06
KK/HlJ m 1.75 0.212   4 0.106 0.122 1.44, 1.92 1.44
LP/J m 1.0 0.195   3 0.113 0.194 0.81, 1.2 -0.69
MA/MyJ m 1.3 0.151   4 0.0753 0.116 1.14, 1.5 0.16
MSM/MsJ m 0.767 0.0577   3 0.0333 0.0753 0.7, 0.8 -1.36
NOD/ShiLtJ m 1.34 0.152   4 0.076 0.113 1.2, 1.53 0.28
NON/ShiLtJ m 1.47 0.129   4 0.0647 0.0882 1.29, 1.6 0.65
NZO/HlLtJ m 1.89 0.179   4 0.0896 0.0945 1.7, 2.1 1.84
NZW/LacJ m 1.92 0.216   4 0.108 0.113 1.66, 2.1 1.93
PERA/EiJ m 1.19 0.11   3 0.0636 0.0923 1.08, 1.3 -0.15
P/J m 1.26 0.144   3 0.0833 0.114 1.1, 1.38 0.05
PL/J m 0.905 0.226   4 0.113 0.249 0.59, 1.1 -0.96
PWD/PhJ m 0.807 0.127   4 0.0637 0.158 0.7, 0.95 -1.24
RIIIS/J m 0.973 0.166   4 0.0832 0.171 0.8, 1.19 -0.77
SEA/GnJ m 1.28 0.0451   4 0.0225 0.0351 1.25, 1.35 0.11
SJL/J m 1.18 0.171   4 0.0854 0.145 1.0, 1.4 -0.18
SM/J m 0.95 0.526   4 0.263 0.554 0.5, 1.7 -0.84
SWR/J m 1.26 0.146   3 0.0841 0.115 1.1, 1.38 0.05
WSB/EiJ m 0.578 0.0903   4 0.0452 0.156 0.5, 0.67 -1.9


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 1.005 0.0979 1.199 0.811
A/J m 0.9975 0.0979 1.1915 0.8035
AKR/J m 1.6667 0.0799 1.8251 1.5082
B6C3F1/J m 1.3333 0.113 1.5574 1.1093
BALB/cByJ m 1.77 0.0979 1.964 1.576
BTBR T+ Itpr3tf/J m 1.8 0.0979 1.994 1.606
BUB/BnJ m 1.6 0.113 1.8241 1.3759
C3H/HeJ m 1.3025 0.0979 1.4965 1.1085
C57BL/10J m 1.305 0.0979 1.499 1.111
C57BL/6J m 1.22 0.0979 1.414 1.026
C57BLKS/J m 1.27 0.0979 1.464 1.076
C57BR/cdJ m 1.4375 0.0979 1.6315 1.2435
C57L/J m 0.9733 0.113 1.1974 0.7493
CAST/EiJ m 0.5475 0.0979 0.7415 0.3535
CBA/J m 1.5225 0.0979 1.7165 1.3285
CZECHII/EiJ m 0.8567 0.113 1.0807 0.6326
DBA/2J m 1.2617 0.0799 1.4201 1.1032
FVB/NJ m 1.4375 0.0979 1.6315 1.2435
JF1/MsJ m 0.87 0.0979 1.064 0.676
KK/HlJ m 1.745 0.0979 1.939 1.551
LP/J m 1.0033 0.113 1.2274 0.7793
MA/MyJ m 1.2975 0.0979 1.4915 1.1035
MSM/MsJ m 0.7667 0.113 0.9907 0.5426
NOD/ShiLtJ m 1.3425 0.0979 1.5365 1.1485
NON/ShiLtJ m 1.4675 0.0979 1.6615 1.2735
NZO/HlLtJ m 1.895 0.0979 2.089 1.701
NZW/LacJ m 1.9225 0.0979 2.1165 1.7285
PERA/EiJ m 1.1933 0.113 1.4174 0.9693
P/J m 1.26 0.113 1.4841 1.0359
PL/J m 0.905 0.0979 1.099 0.711
PWD/PhJ m 0.8075 0.0979 1.0015 0.6135
RIIIS/J m 0.9725 0.0979 1.1665 0.7785
SEA/GnJ m 1.285 0.0979 1.479 1.091
SJL/J m 1.175 0.0979 1.369 0.981
SM/J m 0.95 0.0979 1.144 0.756
SWR/J m 1.2633 0.113 1.4874 1.0393
WSB/EiJ m 0.5775 0.0979 0.7715 0.3835




  GWAS USING LINEAR MIXED MODELS