Project measure / variable:   Threadgill1   GSHratio_ctrl

ID, description, units MPD:19420   GSHratio_ctrl   ratio of reduced (GSH) to oxidized (GSSG) glutathione   [ratio]  control  
acetaminophen study
Data set, strains Threadgill1   inbred w/CC7   35 strains     sex: m     age: 8-17wks
Procedure metabolite quantification
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  STRAIN COMPARISON PLOT
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Threadgill1 - ratio of reduced (GSH) to oxidized (GSSG) glutathione control



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested35 strains
Mean of the strain means19.9   ratio
Median of the strain means19.7   ratio
SD of the strain means± 27.0
Coefficient of variation (CV)1.36
Min–max range of strain means-60.2   –   124   ratio
Mean sample size per strain1.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 30 47740.2185 1591.3406 1.1008 0.394
Residuals 32 46260.9437 1445.6545


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 19.4 6.15   3 3.55 0.316 14.2, 26.2 -0.02
A/J m 19.0 5.52   2   3.9 0.29 15.1, 22.9 -0.03
AKR/J m 38.4 12.3   2   8.7 0.32 29.7, 47.1 0.68
B6C3F1/J m 39.4 30.8   2   21.8 0.782 17.6, 61.1 0.72
BALB/cByJ m 15.3 0.283   2   0.2 0.0185 15.1, 15.5 -0.17
BTBR T+ Itpr3tf/J m 36.4 32.2   2   22.7 0.885 13.6, 59.1 0.61
BUB/BnJ m -43.9 3.82   2   2.7 -0.087 -46.6, -41.2 -2.36
C3H/HeJ m 21.6 2.97   2   2.1 0.137 19.5, 23.7 0.06
C57BL/10J m 14.1 1.77   2   1.25 0.126 12.8, 15.3 -0.21
C57BL/6J m 16.4 5.44   2   3.85 0.333 12.5, 20.2 -0.13
C57BLKS/J m 24.6 4.38   2   3.1 0.178 21.5, 27.7 0.17
C57BR/cdJ m -60.2 109.0   2   76.8 -1.8 -137.0, 16.6 -2.96
C57L/J m -10.2 52.0   2   36.8 -5.1 -47.0, 26.6 -1.11
CAST/EiJ m 22.7 0.0   1   0.0 0.0 22.7, 22.7 0.1
CBA/J m 17.2 0.566   2   0.4 0.0329 16.8, 17.6 -0.1
CZECHII/EiJ m 32.8 0.0   1   0.0 0.0 32.8, 32.8 0.48
DBA/2J m 22.4 2.76   2   1.95 0.123 20.5, 24.4 0.09
FVB/NJ m 14.6 2.47   2   1.75 0.169 12.9, 16.4 -0.2
KK/HlJ m 17.1 5.87   2   4.15 0.344 12.9, 21.2 -0.1
LP/J m 27.2 17.0   2   12.1 0.628 15.1, 39.2 0.27
MA/MyJ m 16.8 2.9   2   2.05 0.173 14.7, 18.8 -0.11
MSM/MsJ m 11.8 0.778   2   0.55 0.0662 11.2, 12.3 -0.3
NOD/ShiLtJ m 31.0 8.63   2   6.1 0.278 24.9, 37.1 0.41
NON/ShiLtJ m 11.8 0.212   2   0.15 0.0179 11.7, 12.0 -0.3
NZO/HlLtJ m 19.7 6.65   2   4.7 0.337 15.0, 24.4 -0.01
NZW/LacJ m 9.95 65.1   2   46.0 6.55 -36.1, 56.0 -0.37
PERA/EiJ m 15.6 4.95   2   3.5 0.317 12.1, 19.1 -0.16
PL/J m 21.9 18.2   2   12.9 0.828 9.09, 34.8 0.07
PWD/PhJ m 20.1 4.45   2   3.15 0.221 17.0, 23.3 0.01
RIIIS/J m 20.1 1.7   2   1.2 0.0844 18.9, 21.3 0.01
SEA/GnJ m 10.8 0.0   2   0.0 0.0 10.8, 10.8 -0.34
SJL/J m 30.9 1.48   2   1.05 0.0481 29.8, 31.9 0.41
SM/J m 124.0 156.0   2   110.0 1.26 13.3, 234.0 3.85
SWR/J m 22.4 0.0   1   0.0 0.0 22.4, 22.4 0.09
WSB/EiJ m 45.1 0.0   1   0.0 0.0 45.1, 45.1 0.93


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 19.4333 21.9519 64.1478 -25.2812
A/J m 19.0 26.8854 73.7639 -35.7639
AKR/J m 38.4 26.8854 93.1639 -16.3639
B6C3F1/J m 39.35 26.8854 94.1139 -15.4139
BALB/cByJ m 15.3 26.8854 70.0639 -39.4639
BTBR T+ Itpr3tf/J m 36.35 26.8854 91.1139 -18.4139
BUB/BnJ m -43.9 26.8854 10.8639 -98.6639
C3H/HeJ m 21.6 26.8854 76.3639 -33.1639
C57BL/10J m 14.05 26.8854 68.8139 -40.7139
C57BL/6J m 16.35 26.8854 71.1139 -38.4139
C57BLKS/J m 24.6 26.8854 79.3639 -30.1639
C57BR/cdJ m -60.2 26.8854 -5.4361 -114.9639
C57L/J m -10.2 26.8854 44.5639 -64.9639
CBA/J m 17.2 26.8854 71.9639 -37.5639
DBA/2J m 22.45 26.8854 77.2139 -32.3139
FVB/NJ m 14.65 26.8854 69.4139 -40.1139
KK/HlJ m 17.05 26.8854 71.8139 -37.7139
LP/J m 27.15 26.8854 81.9139 -27.6139
MA/MyJ m 16.75 26.8854 71.5139 -38.0139
MSM/MsJ m 11.75 26.8854 66.5139 -43.0139
NOD/ShiLtJ m 31.0 26.8854 85.7639 -23.7639
NON/ShiLtJ m 11.85 26.8854 66.6139 -42.9139
NZO/HlLtJ m 19.7 26.8854 74.4639 -35.0639
NZW/LacJ m 9.95 26.8854 64.7139 -44.8139
PERA/EiJ m 15.6 26.8854 70.3639 -39.1639
PL/J m 21.945 26.8854 76.7089 -32.8189
PWD/PhJ m 20.15 26.8854 74.9139 -34.6139
RIIIS/J m 20.1 26.8854 74.8639 -34.6639
SEA/GnJ m 10.8 26.8854 65.5639 -43.9639
SJL/J m 30.85 26.8854 85.6139 -23.9139
SM/J m 123.65 26.8854 178.4139 68.8861




  GWAS USING LINEAR MIXED MODELS