Project measure / variable:   Threadgill1   GSH_ctrl

ID, description, units MPD:19414   GSH_ctrl   reduced glutathione (GSH)   [µmol/g]  control  
acetaminophen study
Data set, strains Threadgill1   inbred w/CC7   35 strains     sex: m     age: 8-17wks
Procedure metabolite quantification
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  STRAIN COMPARISON PLOT
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Threadgill1 - reduced glutathione (GSH) control



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested35 strains
Mean of the strain means4.70   µmol/g
Median of the strain means4.54   µmol/g
SD of the strain means± 1.34
Coefficient of variation (CV)0.285
Min–max range of strain means2.35   –   8.07   µmol/g
Mean sample size per strain1.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 30 111.1667 3.7056 1.0801 0.4142
Residuals 32 109.7799 3.4306


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 5.07 2.55   3 1.47 0.502 3.4, 8.0 0.28
A/J m 6.71 3.81   2   2.7 0.568 4.01, 9.4 1.5
AKR/J m 6.48 3.41   2   2.41 0.526 4.07, 8.89 1.33
B6C3F1/J m 3.98 0.523   2   0.37 0.131 3.61, 4.35 -0.54
BALB/cByJ m 2.75 0.0283   2   0.02 0.0103 2.73, 2.77 -1.46
BTBR T+ Itpr3tf/J m 3.23 0.41   2   0.29 0.127 2.94, 3.52 -1.1
BUB/BnJ m 6.48 2.94   2   2.08 0.454 4.4, 8.56 1.33
C3H/HeJ m 5.73 2.6   2   1.84 0.454 3.89, 7.57 0.77
C57BL/10J m 3.21 0.0849   2   0.06 0.0264 3.15, 3.27 -1.11
C57BL/6J m 4.54 2.26   2   1.59 0.496 2.95, 6.14 -0.12
C57BLKS/J m 3.81 1.58   2   1.11 0.413 2.7, 4.93 -0.66
C57BR/cdJ m 4.95 2.81   2   1.99 0.569 2.96, 6.94 0.19
C57L/J m 2.35 0.325   2   0.23 0.138 2.12, 2.58 -1.75
CAST/EiJ m 6.02 0.0   1   0.0 0.0 6.02, 6.02 0.98
CBA/J m 4.01 0.127   2   0.09 0.0317 3.92, 4.1 -0.52
CZECHII/EiJ m 3.77 0.0   1   0.0 0.0 3.77, 3.77 -0.69
DBA/2J m 4.49 2.49   2   1.76 0.554 2.73, 6.25 -0.16
FVB/NJ m 4.21 0.106   2   0.075 0.0252 4.13, 4.28 -0.37
KK/HlJ m 2.68 1.1   2   0.78 0.412 1.9, 3.46 -1.51
LP/J m 5.0 1.61   2   1.14 0.322 3.86, 6.14 0.22
MA/MyJ m 5.04 2.6   2   1.84 0.516 3.2, 6.88 0.25
MSM/MsJ m 4.95 0.198   2   0.14 0.04 4.81, 5.09 0.19
NOD/ShiLtJ m 8.07 0.467   2   0.33 0.0578 7.74, 8.4 2.51
NON/ShiLtJ m 3.95 0.184   2   0.13 0.0465 3.82, 4.08 -0.56
NZO/HlLtJ m 6.12 1.34   2   0.95 0.22 5.17, 7.07 1.06
NZW/LacJ m 6.04 1.87   2   1.33 0.31 4.72, 7.37 1.0
PERA/EiJ m 4.5 1.48   2   1.04 0.329 3.45, 5.54 -0.15
PL/J m 5.1 0.905   2   0.64 0.177 4.46, 5.74 0.3
PWD/PhJ m 2.92 1.35   2   0.955 0.462 1.97, 3.88 -1.33
RIIIS/J m 5.99 0.806   2   0.57 0.135 5.42, 6.56 0.96
SEA/GnJ m 4.71 1.28   2   0.905 0.272 3.8, 5.61 0.01
SJL/J m 6.38 1.46   2   1.04 0.229 5.35, 7.42 1.25
SM/J m 4.16 2.74   2   1.94 0.66 2.22, 6.1 -0.4
SWR/J m 3.93 0.0   1   0.0 0.0 3.93, 3.93 -0.57
WSB/EiJ m 3.2 0.0   1   0.0 0.0 3.2, 3.2 -1.12


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 5.07 1.0694 7.2482 2.8918
A/J m 6.705 1.3097 9.3728 4.0372
AKR/J m 6.48 1.3097 9.1478 3.8122
B6C3F1/J m 3.98 1.3097 6.6478 1.3122
BALB/cByJ m 2.75 1.3097 5.4178 0.0822
BTBR T+ Itpr3tf/J m 3.23 1.3097 5.8978 0.5622
BUB/BnJ m 6.48 1.3097 9.1478 3.8122
C3H/HeJ m 5.73 1.3097 8.3978 3.0622
C57BL/10J m 3.21 1.3097 5.8778 0.5422
C57BL/6J m 4.545 1.3097 7.2128 1.8772
C57BLKS/J m 3.815 1.3097 6.4828 1.1472
C57BR/cdJ m 4.95 1.3097 7.6178 2.2822
C57L/J m 2.35 1.3097 5.0178 0.0
CBA/J m 4.01 1.3097 6.6778 1.3422
DBA/2J m 4.49 1.3097 7.1578 1.8222
FVB/NJ m 4.205 1.3097 6.8728 1.5372
KK/HlJ m 2.68 1.3097 5.3478 0.0122
LP/J m 5.0 1.3097 7.6678 2.3322
MA/MyJ m 5.04 1.3097 7.7078 2.3722
MSM/MsJ m 4.95 1.3097 7.6178 2.2822
NOD/ShiLtJ m 8.07 1.3097 10.7378 5.4022
NON/ShiLtJ m 3.95 1.3097 6.6178 1.2822
NZO/HlLtJ m 6.12 1.3097 8.7878 3.4522
NZW/LacJ m 6.045 1.3097 8.7128 3.3772
PERA/EiJ m 4.495 1.3097 7.1628 1.8272
PL/J m 5.1 1.3097 7.7678 2.4322
PWD/PhJ m 2.925 1.3097 5.5928 0.2572
RIIIS/J m 5.99 1.3097 8.6578 3.3222
SEA/GnJ m 4.705 1.3097 7.3728 2.0372
SJL/J m 6.385 1.3097 9.0528 3.7172
SM/J m 4.16 1.3097 6.8278 1.4922




  GWAS USING LINEAR MIXED MODELS