Project measure / variable:   Threadgill1   liverwt_ctrl

ID, description, units MPD:19401   liverwt_ctrl   liver weight 24h after treatment   [g]  control  
acetaminophen study
Data set, strains Threadgill1   inbred w/CC7   37 strains     sex: m     age: 8-17wks
Procedure organ weights
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  STRAIN COMPARISON PLOT
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Threadgill1 - liver weight 24h after treatment control



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested37 strains
Mean of the strain means1.12   g
Median of the strain means1.11   g
SD of the strain means± 0.311
Coefficient of variation (CV)0.278
Min–max range of strain means0.550   –   1.88   g
Mean sample size per strain4.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 36 14.1657 0.3935 6.9466 < 0.0001
Residuals 116 6.5708 0.0566


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 0.984 0.091   5 0.0407 0.0925 0.9, 1.12 -0.44
A/J m 1.03 0.126   4 0.0629 0.123 0.9, 1.2 -0.29
AKR/J m 1.44 0.357   4 0.179 0.249 0.9, 1.64 1.03
B6C3F1/J m 1.2 0.294   4 0.147 0.245 0.9, 1.5 0.26
BALB/cByJ m 1.61 0.18   4 0.09 0.112 1.4, 1.84 1.57
BTBR T+ Itpr3tf/J m 1.4 0.535   4 0.268 0.382 0.8, 1.9 0.9
BUB/BnJ m 1.52 0.303   5 0.136 0.2 1.0, 1.7 1.28
C3H/HeJ m 1.2 0.218   4 0.109 0.181 0.9, 1.4 0.26
C57BL/10J m 1.06 0.304   4 0.152 0.286 0.8, 1.35 -0.19
C57BL/6J m 1.27 0.222   4 0.111 0.174 1.0, 1.5 0.48
C57BLKS/J m 1.06 0.224   4 0.112 0.212 0.8, 1.34 -0.19
C57BR/cdJ m 1.25 0.209   4 0.105 0.167 1.0, 1.5 0.42
C57L/J m 0.91 0.359   4 0.179 0.394 0.6, 1.25 -0.68
CAST/EiJ m 0.703 0.195   3 0.113 0.277 0.51, 0.9 -1.34
CBA/J m 1.26 0.182   4 0.0911 0.145 1.0, 1.43 0.45
CZECHII/EiJ m 0.66 0.164   5 0.0736 0.249 0.5, 0.89 -1.48
DBA/2J m 1.11 0.308   4 0.154 0.278 0.8, 1.44 -0.03
FVB/NJ m 1.26 0.189   4 0.0944 0.15 1.1, 1.45 0.45
JF1/MsJ m 0.762 0.075   4 0.0375 0.0984 0.7, 0.85 -1.15
KK/HlJ m 1.4 0.306   4 0.153 0.219 1.0, 1.73 0.9
LP/J m 0.922 0.246   5 0.11 0.267 0.6, 1.2 -0.64
MA/MyJ m 1.26 0.126   4 0.063 0.1 1.1, 1.4 0.45
MSM/MsJ m 0.55 0.0577   4 0.0289 0.105 0.5, 0.6 -1.83
NOD/ShiLtJ m 1.43 0.162   4 0.081 0.113 1.3, 1.63 0.99
NON/ShiLtJ m 1.31 0.309   4 0.155 0.235 1.0, 1.6 0.61
NZO/HlLtJ m 1.88 0.222   4 0.111 0.118 1.6, 2.1 2.44
NZW/LacJ m 1.67 0.287   4 0.143 0.172 1.3, 2.0 1.77
PERA/EiJ m 1.04 0.106   5 0.0474 0.102 0.9, 1.15 -0.26
P/J m 0.915 0.244   4 0.122 0.267 0.7, 1.26 -0.66
PL/J m 1.04 0.376   4 0.188 0.361 0.8, 1.6 -0.26
PWD/PhJ m 0.598 0.159   4 0.0796 0.267 0.4, 0.79 -1.68
RIIIS/J m 1.04 0.159   4 0.0794 0.152 0.9, 1.27 -0.26
SEA/GnJ m 1.11 0.195   4 0.0977 0.176 0.9, 1.33 -0.03
SJL/J m 1.18 0.25   4 0.125 0.213 0.9, 1.5 0.19
SM/J m 0.8 0.141   4 0.0707 0.177 0.7, 1.0 -1.03
SWR/J m 1.06 0.13   5 0.058 0.123 0.9, 1.25 -0.19
WSB/EiJ m 0.57 0.0945   4 0.0473 0.166 0.5, 0.7 -1.77


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 0.984 0.1064 1.1948 0.7732
A/J m 1.025 0.119 1.2607 0.7893
AKR/J m 1.435 0.119 1.6707 1.1993
B6C3F1/J m 1.2 0.119 1.4357 0.9643
BALB/cByJ m 1.61 0.119 1.8457 1.3743
BTBR T+ Itpr3tf/J m 1.4 0.119 1.6357 1.1643
BUB/BnJ m 1.52 0.1064 1.7308 1.3092
C3H/HeJ m 1.2025 0.119 1.4382 0.9668
C57BL/10J m 1.0625 0.119 1.2982 0.8268
C57BL/6J m 1.275 0.119 1.5107 1.0393
C57BLKS/J m 1.06 0.119 1.2957 0.8243
C57BR/cdJ m 1.2525 0.119 1.4882 1.0168
C57L/J m 0.91 0.119 1.1457 0.6743
CAST/EiJ m 0.7033 0.1374 0.9755 0.4312
CBA/J m 1.2575 0.119 1.4932 1.0218
CZECHII/EiJ m 0.66 0.1064 0.8708 0.4492
DBA/2J m 1.11 0.119 1.3457 0.8743
FVB/NJ m 1.2625 0.119 1.4982 1.0268
JF1/MsJ m 0.7625 0.119 0.9982 0.5268
KK/HlJ m 1.3975 0.119 1.6332 1.1618
LP/J m 0.922 0.1064 1.1328 0.7112
MA/MyJ m 1.2575 0.119 1.4932 1.0218
MSM/MsJ m 0.55 0.119 0.7857 0.3143
NOD/ShiLtJ m 1.4325 0.119 1.6682 1.1968
NON/ShiLtJ m 1.315 0.119 1.5507 1.0793
NZO/HlLtJ m 1.875 0.119 2.1107 1.6393
NZW/LacJ m 1.6675 0.119 1.9032 1.4318
PERA/EiJ m 1.038 0.1064 1.2488 0.8272
P/J m 0.915 0.119 1.1507 0.6793
PL/J m 1.04 0.119 1.2757 0.8043
PWD/PhJ m 0.5975 0.119 0.8332 0.3618
RIIIS/J m 1.0425 0.119 1.2782 0.8068
SEA/GnJ m 1.11 0.119 1.3457 0.8743
SJL/J m 1.175 0.119 1.4107 0.9393
SM/J m 0.8 0.119 1.0357 0.5643
SWR/J m 1.058 0.1064 1.2688 0.8472
WSB/EiJ m 0.57 0.119 0.8057 0.3343




  GWAS USING LINEAR MIXED MODELS