Project measure / variable:   Crabbe4   BEC_grip150

ID, description, units MPD:19115   BEC_grip150   blood ethanol concentration   [mg/mL]  150 min post-i.p.  
ethanol study
Data set, strains Crabbe4   inbred   21 strains     sex: both     age: 7-12wks
Procedure alcohol quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Crabbe4 - blood ethanol concentration 150 min post-i.p.



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested21 strains21 strains
Mean of the strain means0.529   mg/mL 0.733   mg/mL
Median of the strain means0.544   mg/mL 0.716   mg/mL
SD of the strain means± 0.226 ± 0.245
Coefficient of variation (CV)0.427 0.334
Min–max range of strain means0.116   –   0.963   mg/mL 0.137   –   1.24   mg/mL
Mean sample size per strain5.9   mice 5.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2.3142 2.3142 63.7281 < 0.0001
strain 20 9.5716 0.4786 13.1791 < 0.0001
sex:strain 20 2.4523 0.1226 3.3765 < 0.0001
Residuals 196 7.1175 0.0363


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.963 0.127   6 0.0519 0.132 0.77, 1.08 1.92
129S1/SvImJ m 1.24 0.238   6 0.0973 0.192 0.91, 1.55 2.07
A/J f 0.643 0.272   6 0.111 0.423 0.11, 0.85 0.5
A/J m 0.808 0.105   6 0.0428 0.13 0.66, 0.92 0.31
AKR/J f 0.2 0.0464   5 0.0207 0.232 0.15, 0.26 -1.46
AKR/J m 0.848 0.135   6 0.055 0.159 0.67, 1.02 0.47
BALB/cByJ f 0.83 0.249   6 0.102 0.3 0.59, 1.24 1.33
BALB/cByJ m 0.998 0.174   6 0.071 0.174 0.77, 1.25 1.08
BTBR T+ Itpr3tf/J f 0.544 0.169   5 0.0755 0.31 0.26, 0.7 0.06
BTBR T+ Itpr3tf/J m 0.716 0.246   5 0.11 0.343 0.31, 0.93 -0.07
C3H/HeJ f 0.605 0.162   6 0.0661 0.268 0.35, 0.8 0.33
C3H/HeJ m 0.662 0.181   6 0.0738 0.273 0.43, 0.97 -0.29
C57BL/6J f 0.895 0.273   12 0.0788 0.305 0.53, 1.43 1.62
C57BL/6J m 0.887 0.12   6 0.0488 0.135 0.75, 1.09 0.63
C57L/J f 0.656 0.128   5 0.0571 0.195 0.43, 0.73 0.56
C57L/J m 1.01 0.128   6 0.0521 0.126 0.88, 1.23 1.13
C58/J f 0.448 0.162   4 0.0811 0.362 0.27, 0.65 -0.36
C58/J m 0.624 0.101   5 0.0452 0.162 0.48, 0.73 -0.44
CAST/EiJ f 0.3 0.191   5 0.0856 0.638 0.08, 0.5 -1.01
CAST/EiJ m 0.137 0.116   3 0.0669 0.848 0.06, 0.27 -2.43
DBA/2J f 0.464 0.228   12 0.066 0.492 0.05, 0.84 -0.29
DBA/2J m 0.702 0.0886   6 0.0362 0.126 0.59, 0.8 -0.13
FVB/NJ f 0.642 0.434   6 0.177 0.677 0.32, 1.5 0.5
FVB/NJ m 0.388 0.149   6 0.0609 0.384 0.24, 0.63 -1.41
MOLF/EiJ f 0.116 0.0767   5 0.0343 0.661 0.07, 0.25 -1.83
MOLF/EiJ m 0.585 0.46   2   0.325 0.786 0.26, 0.91 -0.6
NOD/ShiLtJ f 0.698 0.104   5 0.0466 0.149 0.63, 0.88 0.75
NOD/ShiLtJ m 0.77 0.0707   6 0.0289 0.0918 0.66, 0.84 0.15
NZB/BlNJ f 0.457 0.124   6 0.0507 0.272 0.27, 0.56 -0.32
NZB/BlNJ m 0.808 0.0556   6 0.0227 0.0688 0.72, 0.87 0.31
PERA/EiJ f 0.386 0.213   7 0.0804 0.552 0.21, 0.81 -0.63
PERA/EiJ m 0.562 0.173   4 0.0865 0.308 0.37, 0.79 -0.7
PL/J f 0.693 0.191   6 0.0781 0.276 0.42, 0.9 0.72
PL/J m 1.04 0.191   4 0.0956 0.184 0.83, 1.2 1.25
SJL/J f 0.462 0.152   6 0.0622 0.33 0.22, 0.68 -0.3
SJL/J m 0.865 0.0954   4 0.0477 0.11 0.76, 0.99 0.54
SM/J f 0.558 0.134   6 0.0546 0.239 0.47, 0.81 0.13
SM/J m 0.515 0.142   6 0.058 0.276 0.31, 0.65 -0.89
SPRET/EiJ f 0.21 0.0572   4 0.0286 0.272 0.16, 0.29 -1.41
SPRET/EiJ m 0.698 0.245   4 0.122 0.351 0.52, 1.06 -0.14
SWR/J f 0.348 0.129   6 0.0526 0.37 0.16, 0.5 -0.8
SWR/J m 0.528 0.304   6 0.124 0.575 0.14, 0.93 -0.84


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.9633 0.0778 1.1168 0.8099
129S1/SvImJ m 1.2383 0.0778 1.3918 1.0849
A/J f 0.6433 0.0778 0.7968 0.4899
A/J m 0.8083 0.0778 0.9618 0.6549
AKR/J f 0.2 0.0852 0.3681 0.0319
AKR/J m 0.8483 0.0778 1.0018 0.6949
BALB/cByJ f 0.83 0.0778 0.9834 0.6766
BALB/cByJ m 0.9983 0.0778 1.1518 0.8449
BTBR T+ Itpr3tf/J f 0.544 0.0852 0.7121 0.3759
BTBR T+ Itpr3tf/J m 0.716 0.0852 0.8841 0.5479
C3H/HeJ f 0.605 0.0778 0.7584 0.4516
C3H/HeJ m 0.6617 0.0778 0.8151 0.5082
C57BL/6J f 0.895 0.055 1.0035 0.7865
C57BL/6J m 0.8867 0.0778 1.0401 0.7332
C57L/J f 0.656 0.0852 0.8241 0.4879
C57L/J m 1.0117 0.0778 1.1651 0.8582
C58/J f 0.4475 0.0953 0.6354 0.2596
C58/J m 0.624 0.0852 0.7921 0.4559
CAST/EiJ f 0.3 0.0852 0.4681 0.1319
CAST/EiJ m 0.1367 0.11 0.3536 0.0
DBA/2J f 0.4642 0.055 0.5727 0.3557
DBA/2J m 0.7017 0.0778 0.8551 0.5482
FVB/NJ f 0.6417 0.0778 0.7951 0.4882
FVB/NJ m 0.3883 0.0778 0.5418 0.2349
MOLF/EiJ f 0.116 0.0852 0.2841 0.0
MOLF/EiJ m 0.585 0.1347 0.8507 0.3193
NOD/ShiLtJ f 0.698 0.0852 0.8661 0.5299
NOD/ShiLtJ m 0.77 0.0778 0.9234 0.6166
NZB/BlNJ f 0.4567 0.0778 0.6101 0.3032
NZB/BlNJ m 0.8083 0.0778 0.9618 0.6549
PERA/EiJ f 0.3857 0.072 0.5278 0.2437
PERA/EiJ m 0.5625 0.0953 0.7504 0.3746
PL/J f 0.6933 0.0778 0.8468 0.5399
PL/J m 1.0375 0.0953 1.2254 0.8496
SJL/J f 0.4617 0.0778 0.6151 0.3082
SJL/J m 0.865 0.0953 1.0529 0.6771
SM/J f 0.5583 0.0778 0.7118 0.4049
SM/J m 0.515 0.0778 0.6684 0.3616
SPRET/EiJ f 0.21 0.0953 0.3979 0.0221
SPRET/EiJ m 0.6975 0.0953 0.8854 0.5096
SWR/J f 0.3483 0.0778 0.5018 0.1949
SWR/J m 0.5283 0.0778 0.6818 0.3749


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1.1008 0.055 1.2093 0.9923
A/J both 0.7258 0.055 0.8343 0.6173
AKR/J both 0.5242 0.0577 0.638 0.4104
BALB/cByJ both 0.9142 0.055 1.0227 0.8057
BTBR T+ Itpr3tf/J both 0.63 0.0603 0.7488 0.5112
C3H/HeJ both 0.6333 0.055 0.7418 0.5248
C57BL/6J both 0.8908 0.0476 0.9848 0.7969
C57L/J both 0.8338 0.0577 0.9476 0.72
C58/J both 0.5358 0.0639 0.6618 0.4097
CAST/EiJ both 0.2183 0.0696 0.3556 0.0811
DBA/2J both 0.5829 0.0476 0.6769 0.489
FVB/NJ both 0.515 0.055 0.6235 0.4065
MOLF/EiJ both 0.3505 0.0797 0.5077 0.1933
NOD/ShiLtJ both 0.734 0.0577 0.8478 0.6202
NZB/BlNJ both 0.6325 0.055 0.741 0.524
PERA/EiJ both 0.4741 0.0597 0.5919 0.3563
PL/J both 0.8654 0.0615 0.9867 0.7441
SJL/J both 0.6633 0.0615 0.7846 0.542
SM/J both 0.5367 0.055 0.6452 0.4282
SPRET/EiJ both 0.4538 0.0674 0.5866 0.3209
SWR/J both 0.4383 0.055 0.5468 0.3298




  GWAS USING LINEAR MIXED MODELS