Project measure / variable:   Crabbe4   BEC_grip105

ID, description, units MPD:19114   BEC_grip105   blood ethanol concentration   [mg/mL]  105 min post-i.p.  
ethanol study
Data set, strains Crabbe4   inbred   21 strains     sex: both     age: 7-12wks
Procedure alcohol quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Crabbe4 - blood ethanol concentration 105 min post-i.p.



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested21 strains21 strains
Mean of the strain means1.08   mg/mL 1.26   mg/mL
Median of the strain means1.11   mg/mL 1.29   mg/mL
SD of the strain means± 0.216 ± 0.195
Coefficient of variation (CV)0.199 0.155
Min–max range of strain means0.560   –   1.51   mg/mL 0.810   –   1.58   mg/mL
Mean sample size per strain6.2   mice 5.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1.6526 1.6526 43.8854 < 0.0001
strain 20 7.2955 0.3648 9.6866 < 0.0001
sex:strain 20 2.1399 0.107 2.8412 0.0001
Residuals 204 7.6822 0.0377


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 1.51 0.15   6 0.0611 0.099 1.25, 1.65 1.97
129S1/SvImJ m 1.58 0.186   6 0.076 0.118 1.38, 1.86 1.66
A/J f 1.15 0.307   6 0.125 0.267 0.57, 1.43 0.3
A/J m 1.45 0.117   6 0.0477 0.0803 1.31, 1.58 0.99
AKR/J f 0.808 0.0891   6 0.0364 0.11 0.71, 0.91 -1.28
AKR/J m 1.35 0.0972   6 0.0397 0.072 1.21, 1.46 0.48
BALB/cByJ f 1.41 0.175   6 0.0713 0.124 1.22, 1.66 1.5
BALB/cByJ m 1.41 0.221   6 0.0903 0.157 1.19, 1.72 0.79
BTBR T+ Itpr3tf/J f 1.17 0.319   6 0.13 0.272 0.7, 1.68 0.39
BTBR T+ Itpr3tf/J m 1.2 0.259   5 0.116 0.216 0.79, 1.4 -0.29
C3H/HeJ f 1.13 0.229   6 0.0936 0.203 0.71, 1.38 0.21
C3H/HeJ m 1.1 0.0826   6 0.0337 0.0748 0.97, 1.21 -0.8
C57BL/6J f 1.39 0.256   12 0.074 0.185 1.12, 1.84 1.41
C57BL/6J m 1.39 0.125   6 0.051 0.0898 1.26, 1.63 0.69
C57L/J f 1.23 0.112   6 0.0458 0.091 1.02, 1.35 0.67
C57L/J m 1.42 0.112   6 0.0457 0.0789 1.28, 1.58 0.84
C58/J f 0.98 0.15   4 0.0752 0.153 0.87, 1.2 -0.48
C58/J m 1.33 0.243   6 0.0992 0.183 1.13, 1.77 0.38
CAST/EiJ f 0.803 0.13   6 0.0529 0.161 0.63, 0.98 -1.3
CAST/EiJ m 0.81 0.282   3 0.163 0.348 0.57, 1.12 -2.28
DBA/2J f 0.992 0.282   12 0.0814 0.284 0.56, 1.48 -0.43
DBA/2J m 1.23 0.17   6 0.0692 0.138 1.03, 1.47 -0.13
FVB/NJ f 1.11 0.116   5 0.0519 0.105 1.0, 1.28 0.12
FVB/NJ m 0.937 0.124   6 0.0506 0.132 0.76, 1.13 -1.63
MOLF/EiJ f 0.56 0.261   4 0.131 0.466 0.28, 0.91 -2.43
MOLF/EiJ m 1.12 0.242   3 0.14 0.217 0.86, 1.34 -0.7
NOD/ShiLtJ f 1.14 0.0731   6 0.0298 0.064 1.01, 1.2 0.26
NOD/ShiLtJ m 1.29 0.116   6 0.0474 0.0902 1.17, 1.44 0.18
NZB/BlNJ f 1.09 0.0877   6 0.0358 0.0804 0.99, 1.21 0.02
NZB/BlNJ m 1.21 0.0846   6 0.0345 0.0699 1.06, 1.3 -0.23
PERA/EiJ f 1.06 0.309   8 0.109 0.292 0.46, 1.55 -0.11
PERA/EiJ m 1.24 0.139   4 0.0697 0.113 1.1, 1.43 -0.08
PL/J f 1.2 0.189   6 0.077 0.157 0.94, 1.41 0.53
PL/J m 1.54 0.137   6 0.0559 0.0889 1.31, 1.68 1.46
SJL/J f 1.03 0.215   6 0.0879 0.21 0.85, 1.42 -0.25
SJL/J m 1.35 0.0949   4 0.0474 0.0703 1.21, 1.42 0.48
SM/J f 1.15 0.127   6 0.0517 0.11 0.97, 1.33 0.3
SM/J m 0.995 0.138   6 0.0561 0.138 0.8, 1.13 -1.34
SPRET/EiJ f 0.934 0.197   5 0.088 0.211 0.67, 1.2 -0.7
SPRET/EiJ m 1.32 0.179   3 0.103 0.135 1.21, 1.53 0.33
SWR/J f 0.933 0.116   6 0.0473 0.124 0.79, 1.06 -0.7
SWR/J m 1.1 0.287   6 0.117 0.261 0.65, 1.45 -0.8


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 1.5117 0.0792 1.6679 1.3555
129S1/SvImJ m 1.58 0.0792 1.7362 1.4238
A/J f 1.1467 0.0792 1.3029 0.9905
A/J m 1.4533 0.0792 1.6095 1.2971
AKR/J f 0.8083 0.0792 0.9645 0.6521
AKR/J m 1.35 0.0792 1.5062 1.1938
BALB/cByJ f 1.405 0.0792 1.5612 1.2488
BALB/cByJ m 1.4067 0.0792 1.5629 1.2505
BTBR T+ Itpr3tf/J f 1.1733 0.0792 1.3295 1.0171
BTBR T+ Itpr3tf/J m 1.198 0.0868 1.3691 1.0269
C3H/HeJ f 1.13 0.0792 1.2862 0.9738
C3H/HeJ m 1.105 0.0792 1.2612 0.9488
C57BL/6J f 1.3875 0.056 1.498 1.277
C57BL/6J m 1.3917 0.0792 1.5479 1.2355
C57L/J f 1.2333 0.0792 1.3895 1.0771
C57L/J m 1.4167 0.0792 1.5729 1.2605
C58/J f 0.98 0.097 1.1713 0.7887
C58/J m 1.3267 0.0792 1.4829 1.1705
CAST/EiJ f 0.8033 0.0792 0.9595 0.6471
CAST/EiJ m 0.81 0.112 1.0309 0.5891
DBA/2J f 0.9917 0.056 1.1021 0.8812
DBA/2J m 1.225 0.0792 1.3812 1.0688
FVB/NJ f 1.108 0.0868 1.2791 0.9369
FVB/NJ m 0.9367 0.0792 1.0929 0.7805
MOLF/EiJ f 0.56 0.097 0.7513 0.3687
MOLF/EiJ m 1.12 0.112 1.3409 0.8991
NOD/ShiLtJ f 1.1417 0.0792 1.2979 0.9855
NOD/ShiLtJ m 1.2883 0.0792 1.4445 1.1321
NZB/BlNJ f 1.0917 0.0792 1.2479 0.9355
NZB/BlNJ m 1.21 0.0792 1.3662 1.0538
PERA/EiJ f 1.0575 0.0686 1.1928 0.9222
PERA/EiJ m 1.2375 0.097 1.4288 1.0462
PL/J f 1.2033 0.0792 1.3595 1.0471
PL/J m 1.5417 0.0792 1.6979 1.3855
SJL/J f 1.025 0.0792 1.1812 0.8688
SJL/J m 1.35 0.097 1.5413 1.1587
SM/J f 1.1483 0.0792 1.3045 0.9921
SM/J m 0.995 0.0792 1.1512 0.8388
SPRET/EiJ f 0.934 0.0868 1.1051 0.7629
SPRET/EiJ m 1.3233 0.112 1.5442 1.1024
SWR/J f 0.9333 0.0792 1.0895 0.7771
SWR/J m 1.1 0.0792 1.2562 0.9438


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1.5458 0.056 1.6563 1.4354
A/J both 1.3 0.056 1.4105 1.1895
AKR/J both 1.0792 0.056 1.1896 0.9687
BALB/cByJ both 1.4058 0.056 1.5163 1.2954
BTBR T+ Itpr3tf/J both 1.1857 0.0588 1.3015 1.0698
C3H/HeJ both 1.1175 0.056 1.228 1.007
C57BL/6J both 1.3896 0.0485 1.4852 1.2939
C57L/J both 1.325 0.056 1.4355 1.2145
C58/J both 1.1533 0.0626 1.2768 1.0298
CAST/EiJ both 0.8067 0.0686 0.9419 0.6714
DBA/2J both 1.1083 0.0485 1.204 1.0127
FVB/NJ both 1.0223 0.0588 1.1382 0.9065
MOLF/EiJ both 0.84 0.0741 0.9861 0.6939
NOD/ShiLtJ both 1.215 0.056 1.3255 1.1045
NZB/BlNJ both 1.1508 0.056 1.2613 1.0404
PERA/EiJ both 1.1475 0.0594 1.2647 1.0303
PL/J both 1.3725 0.056 1.483 1.262
SJL/J both 1.1875 0.0626 1.311 1.064
SM/J both 1.0717 0.056 1.1821 0.9612
SPRET/EiJ both 1.1287 0.0709 1.2684 0.989
SWR/J both 1.0167 0.056 1.1271 0.9062




  GWAS USING LINEAR MIXED MODELS