Project measure / variable:   Crabbe4   BEC_grip60

ID, description, units MPD:19113   BEC_grip60   blood ethanol concentration   [mg/mL]  60 min post-i.p.  
ethanol study
Data set, strains Crabbe4   inbred   21 strains     sex: both     age: 7-12wks
Procedure alcohol quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Crabbe4 - blood ethanol concentration 60 min post-i.p.



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested21 strains21 strains
Mean of the strain means1.52   mg/mL 1.62   mg/mL
Median of the strain means1.52   mg/mL 1.62   mg/mL
SD of the strain means± 0.217 ± 0.169
Coefficient of variation (CV)0.143 0.104
Min–max range of strain means1.10   –   1.95   mg/mL 1.29   –   1.88   mg/mL
Mean sample size per strain6.1   mice 5.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.4419 0.4419 8.6557 0.0036
strain 20 6.2482 0.3124 6.1188 < 0.0001
sex:strain 20 2.0828 0.1041 2.0397 0.0071
Residuals 201 10.2625 0.0511


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 1.95 0.081   6 0.0331 0.0415 1.84, 2.06 1.99
129S1/SvImJ m 1.88 0.162   6 0.0663 0.0865 1.78, 2.2 1.57
A/J f 1.47 0.343   6 0.14 0.233 0.86, 1.84 -0.22
A/J m 1.68 0.117   6 0.0478 0.0695 1.49, 1.84 0.38
AKR/J f 1.3 0.0717   6 0.0293 0.0552 1.17, 1.38 -1.01
AKR/J m 1.78 0.144   6 0.059 0.0812 1.61, 1.98 0.98
BALB/cByJ f 1.56 0.152   6 0.0622 0.0976 1.35, 1.81 0.19
BALB/cByJ m 1.54 0.203   6 0.0828 0.132 1.33, 1.89 -0.45
BTBR T+ Itpr3tf/J f 1.43 0.188   6 0.0769 0.132 1.08, 1.62 -0.41
BTBR T+ Itpr3tf/J m 1.67 0.215   5 0.0964 0.129 1.33, 1.9 0.32
C3H/HeJ f 1.52 0.217   6 0.0888 0.143 1.15, 1.75 0.01
C3H/HeJ m 1.46 0.186   6 0.076 0.127 1.2, 1.76 -0.92
C57BL/6J f 1.76 0.192   11 0.0579 0.109 1.49, 2.06 1.11
C57BL/6J m 1.88 0.258   6 0.105 0.137 1.53, 2.11 1.57
C57L/J f 1.41 0.244   6 0.0996 0.173 1.07, 1.65 -0.5
C57L/J m 1.64 0.455   6 0.186 0.278 1.04, 2.34 0.15
C58/J f 1.25 0.219   4 0.11 0.176 1.01, 1.54 -1.24
C58/J m 1.5 0.271   6 0.111 0.181 1.07, 1.79 -0.68
CAST/EiJ f 1.19 0.26   5 0.116 0.218 0.89, 1.58 -1.51
CAST/EiJ m 1.33 0.129   4 0.0645 0.0968 1.2, 1.49 -1.69
DBA/2J f 1.63 0.122   12 0.0352 0.0749 1.37, 1.77 0.51
DBA/2J m 1.82 0.224   6 0.0913 0.123 1.51, 2.18 1.21
FVB/NJ f 1.73 0.349   6 0.143 0.202 1.25, 2.31 0.97
FVB/NJ m 1.59 0.22   6 0.0899 0.138 1.21, 1.79 -0.15
MOLF/EiJ f 1.1 0.309   5 0.138 0.28 0.58, 1.37 -1.93
MOLF/EiJ m 1.29 0.373   4 0.187 0.288 0.75, 1.58 -1.93
NOD/ShiLtJ f 1.54 0.126   5 0.0565 0.082 1.4, 1.67 0.1
NOD/ShiLtJ m 1.62 0.138   6 0.0564 0.0852 1.43, 1.79 0.03
NZB/BlNJ f 1.35 0.305   6 0.124 0.225 0.81, 1.64 -0.78
NZB/BlNJ m 1.78 0.172   6 0.0704 0.0972 1.6, 1.98 0.98
PERA/EiJ f 1.69 0.381   8 0.135 0.225 1.15, 2.44 0.79
PERA/EiJ m 1.79 0.252   4 0.126 0.141 1.63, 2.16 1.04
PL/J f 1.75 0.164   6 0.0671 0.0939 1.6, 1.98 1.07
PL/J m 1.46 0.224   5 0.1 0.154 1.15, 1.76 -0.92
SJL/J f 1.34 0.157   6 0.064 0.117 1.08, 1.46 -0.82
SJL/J m 1.56 0.184   4 0.0919 0.117 1.41, 1.79 -0.33
SM/J f 1.74 0.142   6 0.058 0.0818 1.52, 1.94 1.02
SM/J m 1.64 0.0855   6 0.0349 0.052 1.52, 1.74 0.15
SPRET/EiJ f 1.66 0.152   4 0.076 0.0916 1.53, 1.82 0.65
SPRET/EiJ m 1.58 0.354   2   0.25 0.224 1.33, 1.83 -0.21
SWR/J f 1.52 0.114   6 0.0464 0.0747 1.43, 1.73 0.01
SWR/J m 1.43 0.297   5 0.133 0.207 1.05, 1.87 -1.1


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 1.95 0.0922 2.1319 1.7681
129S1/SvImJ m 1.8767 0.0922 2.0586 1.6948
A/J f 1.4717 0.0922 1.6536 1.2898
A/J m 1.6833 0.0922 1.8652 1.5014
AKR/J f 1.2983 0.0922 1.4802 1.1164
AKR/J m 1.78 0.0922 1.9619 1.5981
BALB/cByJ f 1.56 0.0922 1.7419 1.3781
BALB/cByJ m 1.54 0.0922 1.7219 1.3581
BTBR T+ Itpr3tf/J f 1.4267 0.0922 1.6086 1.2448
BTBR T+ Itpr3tf/J m 1.668 0.1011 1.8673 1.4687
C3H/HeJ f 1.5167 0.0922 1.6986 1.3348
C3H/HeJ m 1.4617 0.0922 1.6436 1.2798
C57BL/6J f 1.7591 0.0681 1.8934 1.6248
C57BL/6J m 1.8783 0.0922 2.0602 1.6964
C57L/J f 1.4133 0.0922 1.5952 1.2314
C57L/J m 1.6383 0.0922 1.8202 1.4564
C58/J f 1.245 0.113 1.4678 1.0222
C58/J m 1.495 0.0922 1.6769 1.3131
CAST/EiJ f 1.19 0.1011 1.3893 0.9907
CAST/EiJ m 1.3325 0.113 1.5553 1.1097
DBA/2J f 1.6258 0.0652 1.7545 1.4972
DBA/2J m 1.815 0.0922 1.9969 1.6331
FVB/NJ f 1.7283 0.0922 1.9102 1.5464
FVB/NJ m 1.5917 0.0922 1.7736 1.4098
MOLF/EiJ f 1.104 0.1011 1.3033 0.9047
MOLF/EiJ m 1.295 0.113 1.5178 1.0722
NOD/ShiLtJ f 1.542 0.1011 1.7413 1.3427
NOD/ShiLtJ m 1.6217 0.0922 1.8036 1.4398
NZB/BlNJ f 1.3533 0.0922 1.5352 1.1714
NZB/BlNJ m 1.775 0.0922 1.9569 1.5931
PERA/EiJ f 1.69 0.0799 1.8475 1.5325
PERA/EiJ m 1.7875 0.113 2.0103 1.5647
PL/J f 1.75 0.0922 1.9319 1.5681
PL/J m 1.456 0.1011 1.6553 1.2567
SJL/J f 1.3367 0.0922 1.5186 1.1548
SJL/J m 1.565 0.113 1.7878 1.3422
SM/J f 1.735 0.0922 1.9169 1.5531
SM/J m 1.645 0.0922 1.8269 1.4631
SPRET/EiJ f 1.66 0.113 1.8828 1.4372
SPRET/EiJ m 1.58 0.1598 1.8951 1.2649
SWR/J f 1.5217 0.0922 1.7036 1.3398
SWR/J m 1.432 0.1011 1.6313 1.2327


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1.9133 0.0652 2.042 1.7847
A/J both 1.5775 0.0652 1.7061 1.4489
AKR/J both 1.5392 0.0652 1.6678 1.4105
BALB/cByJ both 1.55 0.0652 1.6786 1.4214
BTBR T+ Itpr3tf/J both 1.5473 0.0684 1.6822 1.4124
C3H/HeJ both 1.4892 0.0652 1.6178 1.3605
C57BL/6J both 1.8187 0.0573 1.9318 1.7056
C57L/J both 1.5258 0.0652 1.6545 1.3972
C58/J both 1.37 0.0729 1.5138 1.2262
CAST/EiJ both 1.2612 0.0758 1.4107 1.1118
DBA/2J both 1.7204 0.0565 1.8318 1.609
FVB/NJ both 1.66 0.0652 1.7886 1.5314
MOLF/EiJ both 1.1995 0.0758 1.3489 1.0501
NOD/ShiLtJ both 1.5818 0.0684 1.7167 1.4469
NZB/BlNJ both 1.5642 0.0652 1.6928 1.4355
PERA/EiJ both 1.7387 0.0692 1.8752 1.6023
PL/J both 1.603 0.0684 1.7379 1.4681
SJL/J both 1.4508 0.0729 1.5946 1.307
SM/J both 1.69 0.0652 1.8186 1.5614
SPRET/EiJ both 1.62 0.0978 1.8129 1.4271
SWR/J both 1.4768 0.0684 1.6117 1.3419




  GWAS USING LINEAR MIXED MODELS