Project measure / variable:   Crabbe4   BEC_grip30

ID, description, units MPD:19112   BEC_grip30   blood ethanol concentration   [mg/mL]  30 min post-i.p.  
ethanol study
Data set, strains Crabbe4   inbred   21 strains     sex: both     age: 7-12wks
Procedure alcohol quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Crabbe4 - blood ethanol concentration 30 min post-i.p.



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested21 strains21 strains
Mean of the strain means1.48   mg/mL 1.59   mg/mL
Median of the strain means1.46   mg/mL 1.62   mg/mL
SD of the strain means± 0.238 ± 0.217
Coefficient of variation (CV)0.161 0.136
Min–max range of strain means1.11   –   1.94   mg/mL 1.20   –   1.93   mg/mL
Mean sample size per strain6.3   mice 5.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.3503 0.3503 4.7733 0.03
strain 20 10.8377 0.5419 7.3832 < 0.0001
sex:strain 20 2.5184 0.1259 1.7157 0.0326
Residuals 213 15.633 0.0734


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 1.57 0.147   6 0.06 0.0937 1.39, 1.74 0.38
129S1/SvImJ m 1.62 0.255   6 0.104 0.157 1.27, 1.99 0.15
A/J f 1.11 0.331   6 0.135 0.299 0.53, 1.36 -1.55
A/J m 1.45 0.0762   6 0.0311 0.0525 1.33, 1.52 -0.64
AKR/J f 1.11 0.236   6 0.0965 0.213 0.87, 1.48 -1.55
AKR/J m 1.36 0.514   6 0.21 0.378 0.73, 2.18 -1.05
BALB/cByJ f 1.38 0.179   6 0.0731 0.129 1.14, 1.62 -0.41
BALB/cByJ m 1.32 0.17   6 0.0693 0.128 1.09, 1.57 -1.24
BTBR T+ Itpr3tf/J f 1.24 0.0812   6 0.0331 0.0653 1.1, 1.32 -1.0
BTBR T+ Itpr3tf/J m 1.46 0.144   5 0.0645 0.0988 1.32, 1.63 -0.59
C3H/HeJ f 1.42 0.18   6 0.0734 0.126 1.1, 1.6 -0.25
C3H/HeJ m 1.2 0.191   6 0.0779 0.159 0.93, 1.41 -1.79
C57BL/6J f 1.94 0.311   12 0.0899 0.16 1.53, 2.49 1.94
C57BL/6J m 1.92 0.111   6 0.0454 0.058 1.72, 2.01 1.53
C57L/J f 1.74 0.088   6 0.0359 0.0505 1.62, 1.86 1.1
C57L/J m 1.7 0.281   6 0.115 0.166 1.31, 2.16 0.52
C58/J f 1.43 0.0866   4 0.0433 0.0604 1.37, 1.56 -0.2
C58/J m 1.65 0.198   6 0.0807 0.12 1.41, 1.94 0.29
CAST/EiJ f 1.2 0.214   6 0.0873 0.178 0.85, 1.42 -1.17
CAST/EiJ m 1.38 0.204   5 0.0911 0.148 1.09, 1.59 -0.96
DBA/2J f 1.59 0.373   12 0.108 0.236 1.15, 2.3 0.47
DBA/2J m 1.93 0.0989   6 0.0404 0.0512 1.82, 2.1 1.58
FVB/NJ f 1.6 0.193   6 0.0789 0.121 1.29, 1.88 0.51
FVB/NJ m 1.67 0.426   6 0.174 0.255 1.23, 2.47 0.38
MOLF/EiJ f 1.48 0.447   5 0.2 0.302 0.69, 1.75 0.01
MOLF/EiJ m 1.46 0.503   6 0.205 0.345 0.73, 2.03 -0.59
NOD/ShiLtJ f 1.43 0.199   6 0.0812 0.139 1.16, 1.62 -0.2
NOD/ShiLtJ m 1.42 0.162   6 0.0662 0.114 1.23, 1.67 -0.78
NZB/BlNJ f 1.46 0.24   6 0.0979 0.164 1.25, 1.82 -0.08
NZB/BlNJ m 1.87 0.354   6 0.144 0.189 1.31, 2.27 1.3
PERA/EiJ f 1.67 0.258   8 0.0911 0.154 1.25, 1.92 0.8
PERA/EiJ m 1.86 0.182   4 0.0909 0.0976 1.71, 2.07 1.26
PL/J f 1.39 0.292   6 0.119 0.211 0.88, 1.68 -0.37
PL/J m 1.49 0.207   6 0.0844 0.139 1.19, 1.71 -0.45
SJL/J f 1.17 0.238   6 0.097 0.203 0.87, 1.44 -1.3
SJL/J m 1.7 0.395   5 0.177 0.233 1.21, 2.25 0.52
SM/J f 1.93 0.277   6 0.113 0.143 1.53, 2.29 1.9
SM/J m 1.67 0.199   6 0.0813 0.119 1.43, 1.98 0.38
SPRET/EiJ f 1.7 0.378   5 0.169 0.222 1.05, 2.0 0.93
SPRET/EiJ m 1.84 0.291   4 0.145 0.158 1.58, 2.24 1.16
SWR/J f 1.49 0.115   6 0.0468 0.0771 1.35, 1.68 0.05
SWR/J m 1.38 0.32   6 0.131 0.232 0.81, 1.65 -0.96


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 1.5683 0.1106 1.7863 1.3503
129S1/SvImJ m 1.6217 0.1106 1.8397 1.4037
A/J f 1.1067 0.1106 1.3247 0.8887
A/J m 1.45 0.1106 1.668 1.232
AKR/J f 1.11 0.1106 1.328 0.892
AKR/J m 1.3617 0.1106 1.5797 1.1437
BALB/cByJ f 1.3833 0.1106 1.6013 1.1653
BALB/cByJ m 1.3217 0.1106 1.5397 1.1037
BTBR T+ Itpr3tf/J f 1.2433 0.1106 1.4613 1.0253
BTBR T+ Itpr3tf/J m 1.46 0.1212 1.6988 1.2212
C3H/HeJ f 1.4233 0.1106 1.6413 1.2053
C3H/HeJ m 1.1983 0.1106 1.4163 0.9803
C57BL/6J f 1.9417 0.0782 2.0958 1.7875
C57BL/6J m 1.915 0.1106 2.133 1.697
C57L/J f 1.7433 0.1106 1.9613 1.5253
C57L/J m 1.6967 0.1106 1.9147 1.4787
C58/J f 1.4325 0.1355 1.6995 1.1655
C58/J m 1.6483 0.1106 1.8663 1.4303
CAST/EiJ f 1.2033 0.1106 1.4213 0.9853
CAST/EiJ m 1.378 0.1212 1.6168 1.1392
DBA/2J f 1.585 0.0782 1.7392 1.4308
DBA/2J m 1.9317 0.1106 2.1497 1.7137
FVB/NJ f 1.6017 0.1106 1.8197 1.3837
FVB/NJ m 1.67 0.1106 1.888 1.452
MOLF/EiJ f 1.48 0.1212 1.7188 1.2412
MOLF/EiJ m 1.4583 0.1106 1.6763 1.2403
NOD/ShiLtJ f 1.4317 0.1106 1.6497 1.2137
NOD/ShiLtJ m 1.4167 0.1106 1.6347 1.1987
NZB/BlNJ f 1.46 0.1106 1.678 1.242
NZB/BlNJ m 1.8667 0.1106 2.0847 1.6487
PERA/EiJ f 1.6688 0.0958 1.8576 1.4799
PERA/EiJ m 1.8625 0.1355 2.1295 1.5955
PL/J f 1.385 0.1106 1.603 1.167
PL/J m 1.4917 0.1106 1.7097 1.2737
SJL/J f 1.17 0.1106 1.388 0.952
SJL/J m 1.698 0.1212 1.9368 1.4592
SM/J f 1.9317 0.1106 2.1497 1.7137
SM/J m 1.67 0.1106 1.888 1.452
SPRET/EiJ f 1.704 0.1212 1.9428 1.4652
SPRET/EiJ m 1.8375 0.1355 2.1045 1.5705
SWR/J f 1.4867 0.1106 1.7047 1.2687
SWR/J m 1.3767 0.1106 1.5947 1.1587


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1.595 0.0782 1.7492 1.4408
A/J both 1.2783 0.0782 1.4325 1.1242
AKR/J both 1.2358 0.0782 1.39 1.0817
BALB/cByJ both 1.3525 0.0782 1.5067 1.1983
BTBR T+ Itpr3tf/J both 1.3517 0.082 1.5133 1.19
C3H/HeJ both 1.3108 0.0782 1.465 1.1567
C57BL/6J both 1.9283 0.0677 2.0618 1.7948
C57L/J both 1.72 0.0782 1.8742 1.5658
C58/J both 1.5404 0.0874 1.7128 1.3681
CAST/EiJ both 1.2907 0.082 1.4523 1.129
DBA/2J both 1.7583 0.0677 1.8918 1.6248
FVB/NJ both 1.6358 0.0782 1.79 1.4817
MOLF/EiJ both 1.4692 0.082 1.6308 1.3075
NOD/ShiLtJ both 1.4242 0.0782 1.5783 1.27
NZB/BlNJ both 1.6633 0.0782 1.8175 1.5092
PERA/EiJ both 1.7656 0.083 1.9291 1.6021
PL/J both 1.4383 0.0782 1.5925 1.2842
SJL/J both 1.434 0.082 1.5957 1.2723
SM/J both 1.8008 0.0782 1.955 1.6467
SPRET/EiJ both 1.7708 0.0909 1.9499 1.5916
SWR/J both 1.4317 0.0782 1.5858 1.2775




  GWAS USING LINEAR MIXED MODELS