Project measure / variable:   Cheverud1   GLU_clear20_hifat

ID, description, units MPD:17896   GLU_clear20_hifat   glucose levels, area under curve, glucose tolerance test (serum GLU, 10% glucose i.p., 4h fast)   [AUC]  high-fat diet  
high-fat diet study
Data set, strains Cheverud1   LGXSM w/par   17 strains     sex: both     age: 20wks
Procedure glucose tolerance
Ontology mappings

  STRAIN COMPARISON PLOT
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Cheverud1 - glucose levels, area under curve, glucose tolerance test (serum GLU, 10% glucose i.p., 4h fast) high-fat diet



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested15 strains17 strains
Mean of the strain means0.0522   AUC 0.137   AUC
Median of the strain means0.0419   AUC 0.134   AUC
SD of the strain means± 0.0635 ± 0.0667
Coefficient of variation (CV)1.22 0.488
Min–max range of strain means-0.0394   –   0.199   AUC 0.0234   –   0.224   AUC
Mean sample size per strain8.2   mice 7.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.4679 0.4679 29.6161 < 0.0001
strain 14 0.5794 0.0414 2.6193 0.0015
sex:strain 14 0.5314 0.038 2.4023 0.0038
Residuals 223 3.5232 0.0158


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
LGXSM10 f 0.0839 0.0989   9 0.033 1.18 -0.034, 0.243 0.5
LGXSM10 m 0.0679 0.134   10 0.0423 1.97 -0.122, 0.265 -1.03
LGXSM15 f 0.0317 0.107   9 0.0356 3.37 -0.209, 0.142 -0.32
LGXSM15 m 0.119 0.129   11 0.0388 1.08 -0.188, 0.301 -0.27
LGXSM18 f -0.0213 0.0776   7 0.0293 -3.65 -0.125, 0.099 -1.16
LGXSM18 m 0.21 0.142   8 0.0501 0.673 -0.018, 0.414 1.1
LGXSM19 f 0.121 0.104   9 0.0346 0.858 -0.086, 0.242 1.08
LGXSM19 m 0.221 0.0936   8 0.0331 0.425 0.088, 0.346 1.26
LGXSM20 f 0.0199 0.0232   8 0.00819 1.17 -0.006, 0.054 -0.51
LGXSM20 m 0.155 0.0913   6 0.0373 0.59 0.022, 0.277 0.27
LGXSM22 f 0.199 0.182   13 0.0504 0.915 -0.065, 0.579 2.31
LGXSM22 m 0.224 0.09   11 0.0271 0.402 0.109, 0.373 1.31
LGXSM23 f 0.0454 0.0975   8 0.0345 2.15 -0.084, 0.171 -0.11
LGXSM23 m 0.134 0.18   10 0.0568 1.34 -0.193, 0.342 -0.04
LGXSM31 f 0.104 0.116   5 0.0519 1.12 -0.034, 0.255 0.82
LGXSM31 m 0.0234 0.116   7 0.044 4.97 -0.111, 0.196 -1.7
LGXSM33 f 0.0178 0.15   15 0.0386 8.4 -0.199, 0.242 -0.54
LGXSM33 m 0.205 0.136   15 0.035 0.662 -0.026, 0.464 1.02
LGXSM38 f -0.0214 0.0527   7 0.0199 -2.46 -0.08, 0.066 -1.16
LGXSM38 m 0.0772 0.076   4 0.038 0.983 -0.026, 0.156 -0.89
LGXSM39 m 0.174 0.217   3 0.125 1.25 -0.076, 0.308 0.56
LGXSM4 f 0.0389 0.165   8 0.0582 4.23 -0.181, 0.385 -0.21
LGXSM4 m 0.0418 0.0894   6 0.0365 2.14 -0.072, 0.157 -1.42
LGXSM45 f 0.0446 0.204   5 0.0914 4.58 -0.167, 0.383 -0.12
LGXSM45 m 0.184 0.152   3 0.088 0.827 0.009, 0.285 0.71
LGXSM46 f 0.117 0.0727   9 0.0242 0.623 0.027, 0.263 1.02
LGXSM46 m 0.0875 0.107   10 0.0338 1.22 -0.087, 0.252 -0.74
LGXSM48 f 0.0419 0.132   7 0.0498 3.15 -0.141, 0.236 -0.16
LGXSM48 m 0.0934 0.158   8 0.056 1.7 -0.141, 0.406 -0.65
LGXSM5 f -0.0394 0.135   8 0.0477 -3.43 -0.178, 0.241 -1.44
LGXSM5 m 0.213 0.105   9 0.035 0.493 0.082, 0.369 1.14
SM/J m 0.0935 0.0712   6 0.0291 0.762 0.013, 0.214 -0.65


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
LGXSM10 f 0.0839 0.0419 0.1665 0.0013
LGXSM10 m 0.0679 0.0397 0.1462 -0.0104
LGXSM15 f 0.0317 0.0419 0.1142 -0.0509
LGXSM15 m 0.1192 0.0379 0.1939 0.0445
LGXSM18 f -0.0213 0.0475 0.0723 -0.1149
LGXSM18 m 0.2104 0.0444 0.298 0.1228
LGXSM19 f 0.1208 0.0419 0.2033 0.0382
LGXSM19 m 0.2205 0.0444 0.3081 0.1329
LGXSM20 f 0.0199 0.0444 0.1075 -0.0677
LGXSM20 m 0.1548 0.0513 0.256 0.0537
LGXSM22 f 0.1987 0.0349 0.2674 0.13
LGXSM22 m 0.224 0.0379 0.2987 0.1493
LGXSM23 f 0.0454 0.0444 0.133 -0.0422
LGXSM23 m 0.134 0.0397 0.2123 0.0557
LGXSM31 f 0.104 0.0562 0.2148 -0.0068
LGXSM31 m 0.0234 0.0475 0.1171 -0.0702
LGXSM33 f 0.0178 0.0325 0.0818 -0.0462
LGXSM33 m 0.2051 0.0325 0.2691 0.1412
LGXSM38 f -0.0214 0.0475 0.0722 -0.1151
LGXSM38 m 0.0772 0.0628 0.2011 -0.0466
LGXSM4 f 0.0389 0.0444 0.1265 -0.0487
LGXSM4 m 0.0418 0.0513 0.143 -0.0593
LGXSM45 f 0.0446 0.0562 0.1554 -0.0662
LGXSM45 m 0.1843 0.0726 0.3273 0.0413
LGXSM46 f 0.1168 0.0419 0.1993 0.0342
LGXSM46 m 0.0875 0.0397 0.1658 0.0092
LGXSM48 f 0.0419 0.0475 0.1355 -0.0518
LGXSM48 m 0.0934 0.0444 0.181 0.0058
LGXSM5 f -0.0394 0.0444 0.0482 -0.127
LGXSM5 m 0.213 0.0419 0.2956 0.1304


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
LGXSM10 both 0.0759 0.0289 0.1328 0.019
LGXSM15 both 0.0754 0.0282 0.1311 0.0198
LGXSM18 both 0.0945 0.0325 0.1586 0.0304
LGXSM19 both 0.1706 0.0305 0.2308 0.1105
LGXSM20 both 0.0874 0.0339 0.1542 0.0205
LGXSM22 both 0.2113 0.0257 0.2621 0.1606
LGXSM23 both 0.0897 0.0298 0.1484 0.0309
LGXSM31 both 0.0637 0.0368 0.1362 -0.0088
LGXSM33 both 0.1115 0.0229 0.1567 0.0662
LGXSM38 both 0.0279 0.0394 0.1055 -0.0497
LGXSM4 both 0.0404 0.0339 0.1072 -0.0265
LGXSM45 both 0.1145 0.0459 0.2049 0.024
LGXSM46 both 0.1021 0.0289 0.159 0.0452
LGXSM48 both 0.0676 0.0325 0.1317 0.0035
LGXSM5 both 0.0868 0.0305 0.147 0.0266




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA