Phenotype measure:   Cheverud1   GLU_clear10_hifat

ID, description, units MPD:17895   GLU_clear10_hifat   glucose levels, area under curve, glucose tolerance test (serum GLU, 10% glucose i.p., 4h fast)   [AUC]  high-fat diet
high-fat diet study
Data set, strains Cheverud1   LGXSM w/par   17 strains     sex: both     age: 10wks
Procedure glucose tolerance
Ontology mappings

  STRAIN COMPARISON PLOT
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Cheverud1 - glucose levels, area under curve, glucose tolerance test (serum GLU, 10% glucose i.p., 4h fast) high-fat diet



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested15 strains17 strains
Mean of the strain means0.00750   AUC 0.122   AUC
Median of the strain means0.0144   AUC 0.129   AUC
SD of the strain means± 0.0876 ± 0.0656
Coefficient of variation (CV)11.7 0.539
Min–max range of strain means-0.157   –   0.180   AUC -0.0488   –   0.211   AUC
Mean sample size per strain8.1   mice 8.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.7422 0.7422 56.8604 < 0.0001
strain 14 0.9774 0.0698 5.3481 < 0.0001
sex:strain 14 0.3742 0.0267 2.0477 0.0156
Residuals 226 2.9501 0.0131


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
LGXSM10 f -0.0156 0.0671   9 0.0224 -4.31 -0.098, 0.088 -0.26
LGXSM10 m 0.0818 0.0955   12 0.0276 1.17 -0.059, 0.225 -0.61
LGXSM15 f 0.0392 0.106   9 0.0354 2.7 -0.151, 0.216 0.36
LGXSM15 m 0.129 0.096   11 0.029 0.746 0.11
LGXSM18 f -0.157 0.118   9 0.0393 -0.752 -0.334, 0.015 -1.88
LGXSM18 m 0.12 0.225   7 0.0849 1.87 -0.136, 0.375 -0.03
LGXSM19 f 0.138 0.11   9 0.0366 0.793 -0.1, 0.25 1.49
LGXSM19 m 0.211 0.081   8 0.0286 0.384 0.044, 0.297 1.36
LGXSM20 f 0.062 0.0893   8 0.0316 1.44 -0.067, 0.197 0.62
LGXSM20 m 0.11 0.0807   6 0.033 0.732 -0.04, 0.167 -0.18
LGXSM22 f 0.0144 0.139   13 0.0384 9.64 -0.367, 0.209 0.08
LGXSM22 m 0.193 0.106   12 0.0305 0.547 -0.05, 0.367 1.09
LGXSM23 f 0.0147 0.118   6 0.0484 8.08 -0.158, 0.14 0.08
LGXSM23 m 0.12 0.13   10 0.0411 1.08 -0.084, 0.344 -0.03
LGXSM31 f 0.0462 0.0922   4 0.0461 1.99 -0.03, 0.172 0.44
LGXSM31 m 0.0377 0.13   7 0.0493 3.46 -0.137, 0.207 -1.28
LGXSM33 f 0.0102 0.127   15 0.0329 12.5 -0.231, 0.277 0.03
LGXSM33 m 0.172 0.139   17 0.0338 0.811 -0.074, 0.505 0.77
LGXSM38 f 0.0247 0.0786   7 0.0297 3.18 -0.108, 0.149 0.2
LGXSM38 m 0.151 0.106   5 0.0476 0.704 0.048, 0.298 0.45
LGXSM39 m 0.163 0.125   3 0.0722 0.767 0.026, 0.271 0.63
LGXSM4 f -0.0355 0.105   8 0.0371 -2.96 -0.123, 0.192 -0.49
LGXSM4 m 0.0603 0.152   6 0.062 2.52 -0.205, 0.193 -0.94
LGXSM45 f -0.127 0.0884   4 0.0442 -0.696 -0.255, -0.052 -1.54
LGXSM45 m 0.15 0.124   4 0.062 0.826 -0.011, 0.291 0.43
LGXSM46 f -0.00544 0.0752   9 0.0251 -13.8 -0.101, 0.169 -0.15
LGXSM46 m 0.0713 0.0907   10 0.0287 1.27 -0.045, 0.242 -0.77
LGXSM48 f -0.0763 0.0563   6 0.023 -0.737 -0.133, 0.0 -0.96
LGXSM48 m -0.0488 0.0815   8 0.0288 -1.67 -0.197, 0.033 -2.6
LGXSM5 f 0.18 0.103   8 0.0365 0.572 0.016, 0.39 1.97
LGXSM5 m 0.162 0.135   9 0.0451 0.836 -0.109, 0.299 0.61
SM/J m 0.186 0.154   6 0.0627 0.824 -0.021, 0.396 0.98


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
LGXSM10 f -0.0156 0.0381 0.0595 -0.0906
LGXSM10 m 0.0818 0.033 0.1467 0.0168
LGXSM15 f 0.0392 0.0381 0.1143 -0.0358
LGXSM15 m 0.1288 0.0344 0.1967 0.0609
LGXSM18 f -0.157 0.0381 -0.082 -0.232
LGXSM18 m 0.12 0.0432 0.2051 0.0349
LGXSM19 f 0.1382 0.0381 0.2133 0.0632
LGXSM19 m 0.211 0.0404 0.2906 0.1314
LGXSM20 f 0.062 0.0404 0.1416 -0.0176
LGXSM20 m 0.1103 0.0466 0.2022 0.0184
LGXSM22 f 0.0144 0.0317 0.0768 -0.0481
LGXSM22 m 0.1934 0.033 0.2584 0.1284
LGXSM23 f 0.0147 0.0466 0.1066 -0.0772
LGXSM23 m 0.1201 0.0361 0.1913 0.0489
LGXSM31 f 0.0462 0.0571 0.1588 -0.0663
LGXSM31 m 0.0377 0.0432 0.1228 -0.0474
LGXSM33 f 0.0102 0.0295 0.0683 -0.0479
LGXSM33 m 0.1716 0.0277 0.2263 0.117
LGXSM38 f 0.0247 0.0432 0.1098 -0.0604
LGXSM38 m 0.151 0.0511 0.2517 0.0503
LGXSM4 f -0.0355 0.0404 0.0441 -0.1151
LGXSM4 m 0.0603 0.0466 0.1522 -0.0316
LGXSM45 f -0.127 0.0571 -0.0144 -0.2396
LGXSM45 m 0.15 0.0571 0.2626 0.0374
LGXSM46 f -0.0054 0.0381 0.0696 -0.0805
LGXSM46 m 0.0713 0.0361 0.1425 0.0001
LGXSM48 f -0.0763 0.0466 0.0156 -0.1682
LGXSM48 m -0.0487 0.0404 0.0308 -0.1283
LGXSM5 f 0.1805 0.0404 0.2601 0.1009
LGXSM5 m 0.1618 0.0381 0.2368 0.0867


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
LGXSM10 both 0.0331 0.0252 0.0827 -0.0165
LGXSM15 both 0.084 0.0257 0.1346 0.0334
LGXSM18 both -0.0185 0.0288 0.0382 -0.0752
LGXSM19 both 0.1746 0.0278 0.2293 0.1199
LGXSM20 both 0.0862 0.0309 0.147 0.0254
LGXSM22 both 0.1039 0.0229 0.149 0.0588
LGXSM23 both 0.0674 0.0295 0.1255 0.0093
LGXSM31 both 0.042 0.0358 0.1125 -0.0286
LGXSM33 both 0.0909 0.0202 0.1308 0.051
LGXSM38 both 0.0879 0.0334 0.1538 0.0219
LGXSM4 both 0.0124 0.0309 0.0732 -0.0484
LGXSM45 both 0.0115 0.0404 0.0911 -0.0681
LGXSM46 both 0.0329 0.0262 0.0846 -0.0188
LGXSM48 both -0.0625 0.0309 -0.0017 -0.1233
LGXSM5 both 0.1711 0.0278 0.2258 0.1164




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA