Project measure / variable:   Hampton1   RR

ID, description, units MPD:1706   RR   interval between R-waves (RR)   [ms]  
Data set, strains Hampton1   inbred   17 strains     sex: both     age: 9-12wks
Procedure ECG
Ontology mappings

  STRAIN COMPARISON PLOT
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Hampton1 - interval between R-waves (RR)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested17 strains17 strains
Mean of the strain means84.5   ms 79.8   ms
Median of the strain means79.0   ms 76.9   ms
SD of the strain means± 11.8 ± 9.43
Coefficient of variation (CV)0.140 0.118
Min–max range of strain means73.1   –   114   ms 68.3   –   106   ms
Mean sample size per strain7.8   mice 7.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 874.2742 874.2742 22.9287 < 0.0001
strain 15 21919.634 1461.3089 38.3243 < 0.0001
sex:strain 15 3832.3633 255.4909 6.7005 < 0.0001
Residuals 216 8236.0923 38.1301


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 87.1 12.1   8 4.29 0.139 78.5, 116.0 0.22
129S1/SvImJ m 80.7 2.28   8 0.807 0.0283 77.8, 83.3 0.09
A/J f 84.2 8.42   8 2.98 0.1 75.2, 98.3 -0.03
A/J m 80.7 6.42   7 2.43 0.0796 73.8, 93.3 0.09
AKR/J f 83.4 7.07   8 2.5 0.0848 74.2, 93.4 -0.1
AKR/J m 96.6 12.8   8 4.51 0.132 72.9, 114.0 1.78
BALB/cJ f 114.0 7.55   7 2.86 0.0665 98.5, 122.0 2.5
BALB/cJ m 106.0 16.0   8 5.66 0.151 78.5, 121.0 2.78
BTBR T+ Itpr3tf/J f 83.7 5.66   8 2.0 0.0677 73.0, 89.4 -0.07
BTBR T+ Itpr3tf/J m 78.8 3.42   8 1.21 0.0435 73.6, 83.3 -0.11
C3H/HeJ f 76.3 2.92   7 1.1 0.0383 73.1, 82.4 -0.7
C3H/HeJ m 75.4 2.57   8 0.908 0.0341 72.9, 80.8 -0.47
C57BL/6J f 77.2 3.12   8 1.1 0.0404 72.5, 82.2 -0.62
C57BL/6J m 78.6 4.12   8 1.46 0.0525 74.1, 86.7 -0.13
CAST/EiJ f 74.6 2.45   8 0.867 0.0328 72.5, 80.4 -0.84
CAST/EiJ m 68.3 1.3   8 0.461 0.0191 66.9, 70.7 -1.22
CBA/J f 78.8 3.18   8 1.12 0.0404 74.1, 84.5 -0.48
CBA/J m 72.7 1.07   8 0.377 0.0147 70.7, 73.8 -0.75
DBA/2J f 99.1 16.6   6 6.76 0.167 85.5, 126.0 1.23
DBA/2J m 85.6 0.0   1   0.0 0.0 85.6, 85.6 0.61
FVB/NJ f 79.0 7.0   7 2.65 0.0887 73.5, 92.4 -0.47
FVB/NJ m 74.9 1.45   8 0.513 0.0194 73.3, 77.7 -0.52
LP/J f 75.7 2.83   8 1.0 0.0374 71.2, 79.6 -0.75
LP/J m 76.9 2.76   8 0.974 0.0358 72.8, 82.1 -0.31
NOD/ShiLtJ f 75.7 1.7   8 0.602 0.0225 73.3, 78.7 -0.75
NOD/ShiLtJ m 75.1 1.57   8 0.555 0.0209 72.3, 76.9 -0.5
NZB/BlNJ f 75.1 2.22   8 0.785 0.0296 71.1, 78.0 -0.8
NZB/BlNJ m 73.5 2.25   7 0.849 0.0306 71.5, 77.8 -0.67
PL/J f 97.9 8.72   8 3.08 0.089 84.5, 111.0 1.13
PL/J m 85.6 10.5   8 3.73 0.123 74.9, 105.0 0.61
SJL/J f 102.0 4.74   8 1.67 0.0464 95.7, 110.0 1.48
SJL/J m 76.1 1.11   8 0.394 0.0146 74.6, 77.5 -0.39
SWR/J f 73.1 2.87   8 1.02 0.0393 70.6, 78.6 -0.97
SWR/J m 71.3 2.42   5 1.08 0.034 69.3, 75.2 -0.9


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 87.125 2.1832 91.4281 82.8219
129S1/SvImJ m 80.725 2.1832 85.0281 76.4219
A/J f 84.1875 2.1832 88.4906 79.8844
A/J m 80.7286 2.3339 85.3287 76.1284
AKR/J f 83.3875 2.1832 87.6906 79.0844
AKR/J m 96.575 2.1832 100.8781 92.2719
BALB/cJ f 113.6429 2.3339 118.243 109.0427
BALB/cJ m 106.0375 2.1832 110.3406 101.7344
BTBR T+ Itpr3tf/J f 83.6625 2.1832 87.9656 79.3594
BTBR T+ Itpr3tf/J m 78.8 2.1832 83.1031 74.4969
C3H/HeJ f 76.3143 2.3339 80.9144 71.7141
C3H/HeJ m 75.4375 2.1832 79.7406 71.1344
C57BL/6J f 77.2 2.1832 81.5031 72.8969
C57BL/6J m 78.6125 2.1832 82.9156 74.3094
CAST/EiJ f 74.6375 2.1832 78.9406 70.3344
CAST/EiJ m 68.3375 2.1832 72.6406 64.0344
CBA/J f 78.825 2.1832 83.1281 74.5219
CBA/J m 72.65 2.1832 76.9531 68.3469
FVB/NJ f 79.0 2.3339 83.6002 74.3998
FVB/NJ m 74.8875 2.1832 79.1906 70.5844
LP/J f 75.725 2.1832 80.0281 71.4219
LP/J m 76.95 2.1832 81.2531 72.6469
NOD/ShiLtJ f 75.7125 2.1832 80.0156 71.4094
NOD/ShiLtJ m 75.075 2.1832 79.3781 70.7719
NZB/BlNJ f 75.075 2.1832 79.3781 70.7719
NZB/BlNJ m 73.4857 2.3339 78.0859 68.8856
PL/J f 97.9125 2.1832 102.2156 93.6094
PL/J m 85.6 2.1832 89.9031 81.2969
SJL/J f 102.0125 2.1832 106.3156 97.7094
SJL/J m 76.125 2.1832 80.4281 71.8219
SWR/J f 73.1125 2.1832 77.4156 68.8094
SWR/J m 71.3 2.7615 76.743 65.857


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 83.925 1.5437 86.9677 80.8823
A/J both 82.458 1.5979 85.6076 79.3085
AKR/J both 89.9813 1.5437 93.024 86.9385
BALB/cJ both 109.8402 1.5979 112.9897 106.6907
BTBR T+ Itpr3tf/J both 81.2313 1.5437 84.274 78.1885
C3H/HeJ both 75.8759 1.5979 79.0254 72.7264
C57BL/6J both 77.9063 1.5437 80.949 74.8635
CAST/EiJ both 71.4875 1.5437 74.5302 68.4448
CBA/J both 75.7375 1.5437 78.7802 72.6948
FVB/NJ both 76.9438 1.5979 80.0933 73.7942
LP/J both 76.3375 1.5437 79.3802 73.2948
NOD/ShiLtJ both 75.3938 1.5437 78.4365 72.351
NZB/BlNJ both 74.2804 1.5979 77.4299 71.1308
PL/J both 91.7563 1.5437 94.799 88.7135
SJL/J both 89.0688 1.5437 92.1115 86.026
SWR/J both 72.2063 1.7601 75.6755 68.737




  GWAS USING LINEAR MIXED MODELS