Project measure / variable:   Hampton1   HR_VAR

ID, description, units MPD:1705   HR_VAR   heart rate variability   [n/min]  
Data set, strains Hampton1   inbred   17 strains     sex: both     age: 9-12wks
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  STRAIN COMPARISON PLOT
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Hampton1 - heart rate variability



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested17 strains17 strains
Mean of the strain means21.1   n/min 22.3   n/min
Median of the strain means13.4   n/min 12.5   n/min
SD of the strain means± 19.0 ± 23.2
Coefficient of variation (CV)0.901 1.04
Min–max range of strain means5.46   –   68.0   n/min 3.89   –   86.9   n/min
Mean sample size per strain7.7   mice 7.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 198.6531 198.6531 0.5856 0.445
strain 15 45097.5122 3006.5008 8.862 < 0.0001
sex:strain 15 20140.7877 1342.7192 3.9578 < 0.0001
Residuals 214 72601.1139 339.2575


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 9.12 4.9   8 1.73 0.537 3.6, 18.0 -0.63
129S1/SvImJ m 6.55 3.96   8 1.4 0.605 2.0, 13.5 -0.68
A/J f 18.2 10.6   8 3.75 0.581 7.4, 31.2 -0.15
A/J m 14.1 8.18   7 3.09 0.579 5.3, 29.3 -0.35
AKR/J f 9.96 6.23   8 2.2 0.626 4.8, 23.7 -0.59
AKR/J m 15.3 6.73   8 2.38 0.439 8.1, 29.2 -0.3
BALB/cJ f 59.1 42.3   7 16.0 0.716 10.9, 137.0 2.0
BALB/cJ m 32.1 18.4   8 6.5 0.572 6.7, 59.2 0.42
BTBR T+ Itpr3tf/J f 13.4 11.2   8 3.96 0.834 5.5, 36.6 -0.41
BTBR T+ Itpr3tf/J m 5.71 2.6   8 0.921 0.456 3.5, 11.6 -0.71
C3H/HeJ f 68.0 32.9   7 12.4 0.484 6.4, 117.0 2.46
C3H/HeJ m 48.6 40.6   8 14.3 0.835 4.7, 107.0 1.14
C57BL/6J f 10.3 8.97   8 3.17 0.871 5.3, 32.1 -0.57
C57BL/6J m 12.5 9.54   8 3.37 0.766 6.0, 33.9 -0.42
CAST/EiJ f 16.7 17.6   8 6.24 1.06 4.2, 56.5 -0.23
CAST/EiJ m 7.35 3.37   8 1.19 0.458 3.9, 13.8 -0.64
CBA/J f 9.49 2.53   7 0.957 0.267 5.8, 12.3 -0.61
CBA/J m 7.99 2.22   7 0.838 0.278 3.7, 10.8 -0.62
DBA/2J f 42.5 34.1   6 13.9 0.802 11.2, 91.1 1.12
DBA/2J m 86.9 0.0   1   0.0 0.0 86.9, 86.9 2.79
FVB/NJ f 37.7 36.7   7 13.9 0.972 4.3, 93.0 0.87
FVB/NJ m 7.16 3.21   8 1.14 0.448 4.2, 14.3 -0.65
LP/J f 8.14 3.87   8 1.37 0.476 3.7, 14.7 -0.68
LP/J m 21.2 38.5   8 13.6 1.81 4.1, 116.0 -0.05
NOD/ShiLtJ f 6.97 1.15   8 0.406 0.164 5.2, 8.6 -0.74
NOD/ShiLtJ m 3.89 0.653   8 0.231 0.168 2.7, 4.7 -0.79
NZB/BlNJ f 5.46 2.56   8 0.904 0.468 2.6, 8.7 -0.82
NZB/BlNJ m 27.0 38.1   7 14.4 1.41 3.0, 93.3 0.2
PL/J f 16.7 5.93   8 2.1 0.356 8.0, 27.6 -0.23
PL/J m 10.2 7.38   8 2.61 0.724 5.2, 27.7 -0.52
SJL/J f 19.3 9.71   8 3.43 0.504 9.3, 40.1 -0.1
SJL/J m 10.1 5.05   8 1.78 0.497 5.1, 18.7 -0.53
SWR/J f 7.93 3.14   8 1.11 0.396 4.6, 14.7 -0.69
SWR/J m 62.1 39.0   5 17.4 0.628 5.4, 91.2 1.72


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 9.125 6.5121 21.961 0.0
129S1/SvImJ m 6.55 6.5121 19.386 0.0
A/J f 18.25 6.5121 31.086 5.414
A/J m 14.1286 6.9617 27.8509 0.4063
AKR/J f 9.9625 6.5121 22.7985 0.0
AKR/J m 15.3375 6.5121 28.1735 2.5015
BALB/cJ f 59.0714 6.9617 72.7937 45.3491
BALB/cJ m 32.1 6.5121 44.936 19.264
BTBR T+ Itpr3tf/J f 13.4125 6.5121 26.2485 0.5765
BTBR T+ Itpr3tf/J m 5.7125 6.5121 18.5485 0.0
C3H/HeJ f 68.0 6.9617 81.7223 54.2777
C3H/HeJ m 48.6 6.5121 61.436 35.764
C57BL/6J f 10.3 6.5121 23.136 0.0
C57BL/6J m 12.4625 6.5121 25.2985 0.0
CAST/EiJ f 16.7 6.5121 29.536 3.864
CAST/EiJ m 7.35 6.5121 20.186 0.0
CBA/J f 9.4857 6.9617 23.208 0.0
CBA/J m 7.9857 6.9617 21.708 0.0
FVB/NJ f 37.7429 6.9617 51.4652 24.0206
FVB/NJ m 7.1625 6.5121 19.9985 0.0
LP/J f 8.1375 6.5121 20.9735 0.0
LP/J m 21.25 6.5121 34.086 8.414
NOD/ShiLtJ f 6.975 6.5121 19.811 0.0
NOD/ShiLtJ m 3.8875 6.5121 16.7235 0.0
NZB/BlNJ f 5.4625 6.5121 18.2985 0.0
NZB/BlNJ m 27.0143 6.9617 40.7366 13.292
PL/J f 16.675 6.5121 29.511 3.839
PL/J m 10.1875 6.5121 23.0235 0.0
SJL/J f 19.275 6.5121 32.111 6.439
SJL/J m 10.15 6.5121 22.986 0.0
SWR/J f 7.925 6.5121 20.761 0.0
SWR/J m 62.1 8.2372 78.3364 45.8636


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 7.8375 4.6047 16.9139 0.0
A/J both 16.1893 4.7664 25.5843 6.7943
AKR/J both 12.65 4.6047 21.7264 3.5736
BALB/cJ both 45.5857 4.7664 54.9807 36.1907
BTBR T+ Itpr3tf/J both 9.5625 4.6047 18.6389 0.4861
C3H/HeJ both 58.3 4.7664 67.695 48.905
C57BL/6J both 11.3812 4.6047 20.4577 2.3048
CAST/EiJ both 12.025 4.6047 21.1014 2.9486
CBA/J both 8.7357 4.9227 18.4388 0.0
FVB/NJ both 22.4527 4.7664 31.8477 13.0577
LP/J both 14.6937 4.6047 23.7702 5.6173
NOD/ShiLtJ both 5.4312 4.6047 14.5077 0.0
NZB/BlNJ both 16.2384 4.7664 25.6334 6.8434
PL/J both 13.4313 4.6047 22.5077 4.3548
SJL/J both 14.7125 4.6047 23.7889 5.6361
SWR/J both 35.0125 5.2502 45.3612 24.6638




  GWAS USING LINEAR MIXED MODELS