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Project measure / variable:   Hampton1   HR

ID, description, units MPD:1704   HR   heart rate   [n/min]  
Data set, strains Hampton1   inbred   17 strains     sex: both     age: 9-12wks
Procedure ECG
Ontology mappings

  STRAIN COMPARISON PLOT
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Hampton1 - heart rate



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested17 strains17 strains
Mean of the strain means727   n/min 766   n/min
Median of the strain means764   n/min 782   n/min
SD of the strain means± 85.3 ± 72.5
Coefficient of variation (CV)0.117 0.0947
Min–max range of strain means537   –   822   n/min 581   –   878   n/min
Mean sample size per strain7.9   mice 7.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 108564.3134 108564.3134 49.8865 < 0.0001
strain 16 1349695.4387 84355.9649 38.7625 < 0.0001
sex:strain 16 248262.1132 15516.3821 7.1299 < 0.0001
Residuals 234 509236.9107 2176.2261


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 699.0 78.0   8 27.6 0.112 519.0, 764.0 -0.32
129S1/SvImJ m 744.0 21.3   8 7.54 0.0287 720.0, 771.0 -0.3
A/J f 720.0 66.8   8 23.6 0.0929 612.0, 798.0 -0.08
A/J m 747.0 55.1   7 20.8 0.0738 645.0, 813.0 -0.26
AKR/J f 724.0 61.3   8 21.7 0.0847 643.0, 808.0 -0.03
AKR/J m 632.0 90.6   8 32.0 0.143 525.0, 823.0 -1.85
BALB/cJ f 537.0 33.2   8 11.7 0.0619 508.0, 612.0 -2.22
BALB/cJ m 581.0 97.1   8 34.3 0.167 498.0, 765.0 -2.55
BTBR T+ Itpr3tf/J f 721.0 52.4   8 18.5 0.0727 671.0, 824.0 -0.07
BTBR T+ Itpr3tf/J m 763.0 33.3   8 11.8 0.0436 721.0, 815.0 -0.04
C3H/HeJ f 795.0 22.2   7 8.4 0.028 757.0, 829.0 0.8
C3H/HeJ m 800.0 27.3   8 9.64 0.0341 743.0, 831.0 0.47
C57BL/6J f 764.0 36.7   8 13.0 0.048 715.0, 828.0 0.44
C57BL/6J m 764.0 37.0   8 13.1 0.0484 694.0, 810.0 -0.03
CAST/EiJ f 806.0 23.7   8 8.38 0.0294 751.0, 828.0 0.93
CAST/EiJ m 878.0 16.6   8 5.85 0.0188 849.0, 897.0 1.54
CBA/J f 783.0 21.9   8 7.75 0.028 747.0, 810.0 0.66
CBA/J m 831.0 13.7   8 4.83 0.0165 816.0, 851.0 0.89
DBA/2J f 628.0 84.1   8 29.7 0.134 479.0, 702.0 -1.16
DBA/2J m 757.0 34.9   8 12.4 0.0462 715.0, 810.0 -0.13
FVB/NJ f 767.0 63.6   7 24.0 0.083 649.0, 821.0 0.47
FVB/NJ m 794.0 14.1   8 4.98 0.0177 773.0, 812.0 0.38
LP/J f 794.0 29.9   8 10.6 0.0376 754.0, 843.0 0.79
LP/J m 782.0 27.6   8 9.77 0.0353 731.0, 825.0 0.22
NOD/ShiLtJ f 788.0 17.8   8 6.3 0.0226 763.0, 818.0 0.72
NOD/ShiLtJ m 800.0 17.0   8 6.0 0.0212 780.0, 830.0 0.47
NZB/BlNJ f 797.0 19.3   8 6.82 0.0242 770.0, 824.0 0.82
NZB/BlNJ m 820.0 19.7   7 7.44 0.024 790.0, 844.0 0.74
PL/J f 618.0 54.6   8 19.3 0.0884 543.0, 710.0 -1.27
PL/J m 710.0 81.8   8 28.9 0.115 574.0, 801.0 -0.77
SJL/J f 590.0 27.4   8 9.68 0.0464 544.0, 627.0 -1.6
SJL/J m 789.0 11.6   8 4.09 0.0147 775.0, 805.0 0.32
SWR/J f 822.0 30.9   8 10.9 0.0375 764.0, 850.0 1.12
SWR/J m 832.0 31.1   8 11.0 0.0373 780.0, 867.0 0.91


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 698.625 16.4933 731.1193 666.1307
129S1/SvImJ m 743.875 16.4933 776.3693 711.3807
A/J f 719.5 16.4933 751.9943 687.0057
A/J m 747.2857 17.6321 782.0236 712.5479
AKR/J f 724.125 16.4933 756.6193 691.6307
AKR/J m 632.125 16.4933 664.6193 599.6307
BALB/cJ f 537.0 16.4933 569.4943 504.5057
BALB/cJ m 580.625 16.4933 613.1193 548.1307
BTBR T+ Itpr3tf/J f 720.75 16.4933 753.2443 688.2557
BTBR T+ Itpr3tf/J m 763.0 16.4933 795.4943 730.5057
C3H/HeJ f 795.2857 17.6321 830.0236 760.5479
C3H/HeJ m 800.375 16.4933 832.8693 767.8807
C57BL/6J f 764.5 16.4933 796.9943 732.0057
C57BL/6J m 764.0 16.4933 796.4943 731.5057
CAST/EiJ f 805.5 16.4933 837.9943 773.0057
CAST/EiJ m 878.25 16.4933 910.7443 845.7557
CBA/J f 782.75 16.4933 815.2443 750.2557
CBA/J m 831.125 16.4933 863.6193 798.6307
DBA/2J f 627.75 16.4933 660.2443 595.2557
DBA/2J m 756.875 16.4933 789.3693 724.3807
FVB/NJ f 766.5714 17.6321 801.3093 731.8336
FVB/NJ m 794.375 16.4933 826.8693 761.8807
LP/J f 793.625 16.4933 826.1193 761.1307
LP/J m 782.375 16.4933 814.8693 749.8807
NOD/ShiLtJ f 787.5 16.4933 819.9943 755.0057
NOD/ShiLtJ m 799.875 16.4933 832.3693 767.3807
NZB/BlNJ f 797.375 16.4933 829.8693 764.8807
NZB/BlNJ m 820.4286 17.6321 855.1664 785.6907
PL/J f 618.0 16.4933 650.4943 585.5057
PL/J m 710.125 16.4933 742.6193 677.6307
SJL/J f 590.0 16.4933 622.4943 557.5057
SJL/J m 788.75 16.4933 821.2443 756.2557
SWR/J f 822.0 16.4933 854.4943 789.5057
SWR/J m 832.375 16.4933 864.8693 799.8807


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 721.25 11.6625 744.2269 698.2731
A/J both 733.3929 12.0718 757.1762 709.6095
AKR/J both 678.125 11.6625 701.1019 655.1481
BALB/cJ both 558.8125 11.6625 581.7894 535.8356
BTBR T+ Itpr3tf/J both 741.875 11.6625 764.8519 718.8981
C3H/HeJ both 797.8304 12.0718 821.6137 774.047
C57BL/6J both 764.25 11.6625 787.2269 741.2731
CAST/EiJ both 841.875 11.6625 864.8519 818.8981
CBA/J both 806.9375 11.6625 829.9144 783.9606
DBA/2J both 692.3125 11.6625 715.2894 669.3356
FVB/NJ both 780.4732 12.0718 804.2566 756.6898
LP/J both 788.0 11.6625 810.9769 765.0231
NOD/ShiLtJ both 793.6875 11.6625 816.6644 770.7106
NZB/BlNJ both 808.9018 12.0718 832.6852 785.1184
PL/J both 664.0625 11.6625 687.0394 641.0856
SJL/J both 689.375 11.6625 712.3519 666.3981
SWR/J both 827.1875 11.6625 850.1644 804.2106




  GWAS USING LINEAR MIXED MODELS