Project measure / variable:   Gershenfeld1   LDtransits_Rx

ID, description, units MPD:16211   LDtransits_Rx   number of transitions between light and dark compartments in 10 min   [n]  imipramine 30mg/kg  
imipramine study
Data set, strains Gershenfeld1   inbred   12 strains     sex: m     age: 5-10wks
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  STRAIN COMPARISON PLOT
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Gershenfeld1 - number of transitions between light and dark compartments in 10 min imipramine 30mg/kg



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested12 strains
Mean of the strain means23.2   n
Median of the strain means19.8   n
SD of the strain means± 18.6
Coefficient of variation (CV)0.801
Min–max range of strain means0.200   –   53.0   n
Mean sample size per strain4.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 11 18288.0048 1662.5459 19.5777 < 0.0001
Residuals 48 4076.1786 84.9204


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S6/SvEvTac m 12.6 11.0   5 4.92 0.872 2.0, 28.0 -0.57
A/J m 0.2 0.447   5 0.2 2.24 -1.24
AKR/J m 23.0 9.62   5 4.3 0.418 13.0, 36.0 -0.01
BALB/cJ m 3.4 5.5   5 2.46 1.62 -1.07
C3H/HeJ m 24.4 4.34   5 1.94 0.178 20.0, 30.0 0.07
C57BL/6J m 46.6 11.6   5 5.17 0.248 38.0, 64.0 1.26
Crl:NMRI(Han) m 53.0 16.9   4 8.44 0.318 28.0, 65.0 1.61
DBA/2J m 16.6 5.5   5 2.46 0.332 13.0, 26.0 -0.35
FVB/NJ m 53.0 9.95   5 4.45 0.188 41.0, 64.0 1.61
LP/J m 10.7 10.3   7 3.88 0.957 -0.67
SENCARA/PtJ m 8.4 9.76   5 4.37 1.16 -0.8
SWR/J m 26.2 5.97   4 2.98 0.227 22.0, 35.0 0.16


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S6/SvEvTac m 12.6 4.1212 20.8862 4.3138
A/J m 0.2 4.1212 8.4862 0.0
AKR/J m 23.0 4.1212 31.2862 14.7138
BALB/cJ m 3.4 4.1212 11.6862 0.0
C3H/HeJ m 24.4 4.1212 32.6862 16.1138
C57BL/6J m 46.6 4.1212 54.8862 38.3138
Crl:NMRI(Han) m 53.0 4.6076 62.2642 43.7358
DBA/2J m 16.6 4.1212 24.8862 8.3138
FVB/NJ m 53.0 4.1212 61.2862 44.7138
LP/J m 10.7143 3.483 17.7174 3.7112
SENCARA/PtJ m 8.4 4.1212 16.6862 0.1138
SWR/J m 26.25 4.6076 35.5142 16.9858




  GWAS USING LINEAR MIXED MODELS