Project measure / variable:   Gershenfeld1   TST_immobility_pct

ID, description, units MPD:16205   TST_immobility_pct   TST immobility percentage, imipramine vs. saline, 6 min test   [%]  
imipramine study
Data set, strains Gershenfeld1   inbred   12 strains     sex: m     age: 5-10wks
Procedure tail suspension test
Ontology mappings

  STRAIN COMPARISON PLOT
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Gershenfeld1 - TST immobility percentage, imipramine vs. saline, 6 min test



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested12 strains
Mean of the strain means-11.4   %
Median of the strain means-10.4   %
SD of the strain means± 16.8
Coefficient of variation (CV)-1.47
Min–max range of strain means-35.5   –   30.5   %
Mean sample size per strain5.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 11 15472.5633 1406.5967 7.4093 < 0.0001
Residuals 50 9492.0654 189.8413


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S6/SvEvTac m -7.41 3.98   5 1.78 -0.537 -14.2, -3.86 0.24
A/J m -10.7 7.5   5 3.35 -0.699 -17.2, -0.43 0.04
AKR/J m 30.5 14.3   5 6.4 0.47 14.7, 51.1 2.5
BALB/cJ m -12.4 18.1   5 8.12 -1.47 -26.9, 18.9 -0.06
C3H/HeJ m -18.6 23.5   5 10.5 -1.26 -49.9, 9.88 -0.43
C57BL/6J m -8.69 5.61   5 2.51 -0.646 -17.6, -2.32 0.16
Crl:NMRI(Han) m -35.5 20.7   5 9.28 -0.585 -54.2, -5.91 -1.44
DBA/2J m -32.3 12.3   5 5.51 -0.381 -45.1, -18.8 -1.25
FVB/NJ m -23.2 12.8   5 5.73 -0.552 -42.2, -9.86 -0.7
LP/J m -10.2 15.7   7 5.95 -1.54 -33.1, 9.42 0.07
SENCARA/PtJ m -4.95 5.82   5 2.6 -1.18 -13.2, 0.54 0.39
SWR/J m -3.5 5.48   5 2.45 -1.56 -12.1, 1.49 0.47


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S6/SvEvTac m -7.414 6.1618 4.9624 -19.7904
A/J m -10.736 6.1618 1.6404 -23.1124
AKR/J m 30.48 6.1618 42.8564 18.1036
BALB/cJ m -12.38 6.1618 -0.0036 -24.7564
C3H/HeJ m -18.612 6.1618 -6.2356 -30.9884
C57BL/6J m -8.686 6.1618 3.6904 -21.0624
Crl:NMRI(Han) m -35.482 6.1618 -23.1056 -47.8584
DBA/2J m -32.34 6.1618 -19.9636 -44.7164
FVB/NJ m -23.212 6.1618 -10.8356 -35.5884
LP/J m -10.2157 5.2077 0.2443 -20.6757
SENCARA/PtJ m -4.946 6.1618 7.4304 -17.3224
SWR/J m -3.504 6.1618 8.8724 -15.8804




  GWAS USING LINEAR MIXED MODELS