Project measure / variable:   Chang1   cone_Bwave

ID, description, units MPD:15705   cone_Bwave   b-wave amplitude of cone photoreceptors (ERG)   [µV]  
Data set, strains Chang1   inbred   16 strains     sex: both     age: >7wks
Procedure electroretinography
Ontology mappings

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  STRAIN COMPARISON PLOT
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Chang1 - b-wave amplitude of cone photoreceptors (ERG)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested14 strains9 strains
Mean of the strain means55.2   µV 71.7   µV
Median of the strain means47.0   µV 69.8   µV
SD of the strain means± 25.0 ± 40.4
Coefficient of variation (CV)0.453 0.564
Min–max range of strain means29.0   –   104   µV 5.00   –   143   µV
Mean sample size per strain10.4   mice 6.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 18252.8528 18252.8528 15.5087 0.0001
strain 6 124562.0062 20760.3344 17.6392 < 0.0001
sex:strain 6 5395.6595 899.2766 0.7641 0.5988
Residuals 248 291881.97 1176.9434


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 29.0 23.0   17 5.58 0.793 -1.05
BALB/cByJ f 49.0 30.2   10 9.56 0.617 14.0, 100.0 -0.25
BALB/cByJ m 48.0 28.0   5 12.5 0.583 20.0, 80.0 -0.59
BALB/cJ f 45.0 25.7   9 8.57 0.571 15.0, 90.0 -0.41
C57BL/6J f 95.7 35.8   62 4.55 0.374 15.0, 180.0 1.62
C57BL/6J m 102.0 31.1   88 3.31 0.304 35.0, 200.0 0.75
C57BR/cdJ f 88.0 36.6   5 16.4 0.416 51.0, 139.0 1.31
CAST/EiJ f 36.8 9.6   4 4.8 0.261 27.0, 45.0 -0.74
CE/J f 62.2 25.0   10 7.9 0.402 32.0, 99.0 0.28
CE/J m 92.0 33.8   5 15.1 0.368 45.0, 139.0 0.5
CZECHII/EiJ f 44.0 10.7   4 5.34 0.243 34.0, 59.0 -0.45
CZECHII/EiJ m 41.2 11.7   4 5.85 0.284 24.0, 50.0 -0.75
DBA/2J f 65.3 30.0   7 11.3 0.459 15.0, 105.0 0.4
LP/J f 33.5 26.3   11 7.92 0.783 10.0, 86.0 -0.87
NZW/LacJ f 104.0 42.4   9 14.1 0.409 50.0, 160.0 1.95
NZW/LacJ m 143.0 29.4   4 14.7 0.206 115.0, 184.0 1.76
PERA/EiJ f 57.5 49.6   29 9.21 0.862 0.09
PERA/EiJ m 69.8 31.1   17 7.53 0.445 -0.05
PWK/PhJ m 91.0 9.87   4 4.93 0.108 80.0, 104.0 0.48
SPRET/EiJ f 32.6 9.76   5 4.37 0.299 20.0, 47.0 -0.9
SWR/J m 5.0 10.0   4 5.0 2.0 -1.65
WSB/EiJ f 30.4 21.3   9 7.12 0.701 -0.99
WSB/EiJ m 53.2 21.8   6 8.9 0.41 29.0, 78.0 -0.46


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BALB/cByJ f 49.0 10.8487 70.3673 27.6327
BALB/cByJ m 48.0 15.3424 78.218 17.782
C57BL/6J f 95.7097 4.3569 104.291 87.1283
C57BL/6J m 102.3409 3.6571 109.5438 95.138
CE/J f 62.2 10.8487 83.5673 40.8327
CE/J m 92.0 15.3424 122.218 61.782
CZECHII/EiJ f 44.0 17.1533 77.7847 10.2153
CZECHII/EiJ m 41.25 17.1533 75.0347 7.4653
NZW/LacJ f 103.7778 11.4355 126.3009 81.2546
NZW/LacJ m 142.75 17.1533 176.5347 108.9653
PERA/EiJ f 57.5172 6.3706 70.0646 44.9699
PERA/EiJ m 69.8235 8.3206 86.2115 53.4355
WSB/EiJ f 30.4444 11.4355 52.9676 7.9213
WSB/EiJ m 53.1667 14.0056 80.7518 25.5815


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
BALB/cByJ both 48.5 9.3953 67.0047 29.9953
C57BL/6J both 99.0253 2.8442 104.6271 93.4235
CE/J both 77.1 9.3953 95.6047 58.5953
CZECHII/EiJ both 42.625 12.1292 66.5144 18.7356
NZW/LacJ both 123.2639 10.3079 143.566 102.9618
PERA/EiJ both 63.6704 5.2397 73.9903 53.3505
WSB/EiJ both 41.8056 9.0406 59.6117 23.9994




  GWAS USING LINEAR MIXED MODELS