Phenotype measure:   Chang1   rod_Bwave

ID, description, units MPD:15702   rod_Bwave   b-wave amplitude of rod photoreceptors (ERG)   [µV]
Data set, strains Chang1   inbred   15 strains     sex: both     age: >7wks
Procedure electroretinography
Ontology mappings

  STRAIN COMPARISON PLOT
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Chang1 - b-wave amplitude of rod photoreceptors (ERG)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested15 strains9 strains
Mean of the strain means133   µV 153   µV
Median of the strain means128   µV 132   µV
SD of the strain means± 46.2 ± 83.1
Coefficient of variation (CV)0.348 0.544
Min–max range of strain means73.9   –   258   µV 11.2   –   288   µV
Mean sample size per strain10.7   mice 6.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 144386.225 144386.225 14.9751 0.0001
strain 6 1286900.2169 214483.3695 22.2453 < 0.0001
sex:strain 6 9547.8819 1591.3136 0.165 0.9858
Residuals 251 2420072.68 9641.7238


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 103.0 70.3   17 17.0 0.682 15.0, 230.0 -0.64
BALB/cByJ f 129.0 73.3   10 23.2 0.567 14.0, 250.0 -0.08
BALB/cByJ m 147.0 49.6   5 22.2 0.338 97.0, 229.0 -0.07
BALB/cJ f 190.0 81.2   9 27.1 0.428 105.0, 320.0 1.24
C57BL/10J f 136.0 51.2   14 13.7 0.377 55.0, 220.0 0.07
C57BL/6J f 258.0 110.0   63 13.9 0.426 60.0, 610.0 2.71
C57BL/6J m 270.0 112.0   90 11.8 0.414 85.0, 740.0 1.41
C57BR/cdJ f 178.0 77.2   5 34.5 0.434 120.0, 295.0 0.98
CAST/EiJ f 128.0 21.0   4 10.5 0.164 107.0, 154.0 -0.1
CE/J f 132.0 39.9   10 12.6 0.302 77.0, 182.0 -0.02
CE/J m 132.0 46.4   5 20.8 0.351 70.0, 194.0 -0.25
CZECHII/EiJ f 109.0 38.4   4 19.2 0.352 77.0, 160.0 -0.51
CZECHII/EiJ m 113.0 9.02   4 4.51 0.0798 100.0, 120.0 -0.48
DBA/2J f 125.0 58.7   7 22.2 0.469 -0.17
LP/J f 99.5 72.3   11 21.8 0.727 25.0, 241.0 -0.72
NZW/LacJ f 138.0 61.2   9 20.4 0.444 40.0, 210.0 0.11
NZW/LacJ m 154.0 48.5   4 24.3 0.316 95.0, 197.0 0.02
PERA/EiJ f 99.7 107.0   29 19.9 1.08 -0.72
PERA/EiJ m 128.0 68.4   17 16.6 0.535 -0.3
PWK/PhJ m 288.0 13.5   4 6.74 0.0467 269.0, 300.0 1.63
SPRET/EiJ f 92.2 19.4   5 8.69 0.211 69.0, 115.0 -0.88
SWR/J m 11.2 14.4   4 7.18 1.28 -1.7
WSB/EiJ f 73.9 54.6   9 18.2 0.739 -1.27
WSB/EiJ m 131.0 61.9   6 25.3 0.473 69.0, 215.0 -0.26


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BALB/cByJ f 129.1 31.0511 190.254 67.946
BALB/cByJ m 147.0 43.9129 233.4848 60.5152
C57BL/6J f 258.3016 12.3711 282.6659 233.9373
C57BL/6J m 269.7222 10.3504 290.1069 249.3376
CE/J f 132.2 31.0511 193.354 71.046
CE/J m 132.4 43.9129 218.8848 45.9152
CZECHII/EiJ f 109.25 49.0961 205.9429 12.5571
CZECHII/EiJ m 113.0 49.0961 209.6929 16.3071
NZW/LacJ f 138.0 32.7308 202.4619 73.5381
NZW/LacJ m 153.75 49.0961 250.4429 57.0571
PERA/EiJ f 99.6897 18.2338 135.6005 63.7788
PERA/EiJ m 127.7647 23.8151 174.6676 80.8618
WSB/EiJ f 73.8889 32.7308 138.3508 9.427
WSB/EiJ m 131.0 40.0868 209.9494 52.0506


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
BALB/cByJ both 138.05 26.8911 191.0109 85.0891
C57BL/6J both 264.0119 8.0649 279.8955 248.1283
CE/J both 132.3 26.8911 185.2609 79.3391
CZECHII/EiJ both 111.125 34.7162 179.4972 42.7528
NZW/LacJ both 145.875 29.5031 203.9802 87.7698
PERA/EiJ both 113.7272 14.9969 143.2631 84.1913
WSB/EiJ both 102.4444 25.8759 153.4061 51.4828




  GWAS USING LINEAR MIXED MODELS