Phenotype measure:   Richfield1   DA_turnover2

ID, description, units MPD:14527   DA_turnover2   dopamine turnover ([DOPAC] + [HVA]/[DA])   [ratio]
Data set, strains Richfield1   inbred   15 strains     sex: m     age: 7-9wks
Procedure neurotransmitter quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Richfield1 - dopamine turnover ([DOPAC] + [HVA]/[DA])



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested15 strains
Mean of the strain means23.7   ratio
Median of the strain means21.7   ratio
SD of the strain means± 5.03
Coefficient of variation (CV)0.212
Min–max range of strain means18.5   –   32.6   ratio
Mean sample size per strain9.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 14 3647.1239 260.5089 7.2166 < 0.0001
Residuals 143 5162.1004 36.0986


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 21.7 2.43   10 0.768 0.112 17.8, 25.2 -0.4
A/HeJ m 19.6 4.7   10 1.48 0.24 11.7, 27.0 -0.82
A/J m 30.1 4.71   10 1.49 0.156 23.4, 39.5 1.27
AKR/J m 24.9 3.75   10 1.19 0.15 18.7, 31.4 0.24
B10.D2-Hc0 m 32.6 7.92   10 2.5 0.243 26.2, 52.2 1.77
BALB/cByJ m 30.0 8.68   9 2.89 0.289 20.3, 49.6 1.25
BALB/cJ m 32.6 6.58   10 2.08 0.201 23.0, 47.0 1.77
C3H/HeJ m 21.4 2.7   10 0.854 0.126 16.1, 26.1 -0.46
C57BL/6J m 19.8 8.5   20 1.9 0.43 11.4, 52.2 -0.78
CAST/EiJ m 19.8 9.69   10 3.06 0.488 10.1, 37.3 -0.78
DBA/2J m 21.9 3.82   10 1.21 0.175 15.3, 28.7 -0.36
MRL/MpJ m 21.4 2.9   10 0.918 0.136 18.5, 28.4 -0.46
NZB/BlNJ m 19.4 5.28   10 1.67 0.272 14.4, 29.7 -0.86
NZW/LacJ m 22.0 3.06   10 0.967 0.139 17.8, 27.4 -0.34
SPRET/EiJ m 18.5 5.05   9 1.68 0.273 12.0, 30.5 -1.04


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129X1/SvJ m 21.67 1.9 25.4256 17.9144
A/HeJ m 19.59 1.9 23.3456 15.8344
A/J m 30.13 1.9 33.8856 26.3744
AKR/J m 24.94 1.9 28.6956 21.1844
B10.D2-Hc0 m 32.62 1.9 36.3756 28.8644
BALB/cByJ m 30.0333 2.0027 33.9921 26.0745
BALB/cJ m 32.65 1.9 36.4056 28.8944
C3H/HeJ m 21.4 1.9 25.1556 17.6444
C57BL/6J m 19.755 1.3435 22.4106 17.0994
CAST/EiJ m 19.84 1.9 23.5956 16.0844
DBA/2J m 21.87 1.9 25.6256 18.1144
MRL/MpJ m 21.35 1.9 25.1056 17.5944
NZB/BlNJ m 19.38 1.9 23.1356 15.6244
NZW/LacJ m 22.0 1.9 25.7556 18.2444
SPRET/EiJ m 18.5111 2.0027 22.4699 14.5523




  GWAS USING LINEAR MIXED MODELS