Phenotype measure:   Richfield1   HVA

ID, description, units MPD:14524   HVA   4-hydroxy-3-methoxyphenylacetic acid (HVA), ng per mg total protein   [ratio]
Data set, strains Richfield1   inbred   15 strains     sex: m     age: 7-9wks
Procedure neurotransmitter quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Richfield1 - 4-hydroxy-3-methoxyphenylacetic acid (HVA), ng per mg total protein



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested15 strains
Mean of the strain means20.7   ratio
Median of the strain means23.0   ratio
SD of the strain means± 10.8
Coefficient of variation (CV)0.521
Min–max range of strain means4.79   –   41.2   ratio
Mean sample size per strain9.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 14 16320.7984 1165.7713 7.7781 < 0.0001
Residuals 143 21432.5514 149.878


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 32.4 15.8   10 4.98 0.486 21.3, 67.0 1.08
A/HeJ m 5.51 1.23   10 0.387 0.222 2.8, 6.6 -1.41
A/J m 25.7 11.2   10 3.54 0.434 13.9, 48.2 0.46
AKR/J m 27.9 16.6   10 5.24 0.594 11.6, 58.0 0.67
B10.D2-Hc0 m 41.2 28.6   10 9.03 0.693 19.3, 102.0 1.9
BALB/cByJ m 23.0 11.2   9 3.75 0.489 13.2, 50.4 0.21
BALB/cJ m 29.1 11.0   10 3.48 0.379 15.1, 51.2 0.78
C3H/HeJ m 21.1 10.1   10 3.19 0.476 11.7, 41.9 0.04
C57BL/6J m 15.1 10.3   20 2.31 0.684 5.7, 43.0 -0.52
CAST/EiJ m 8.14 2.15   10 0.68 0.264 4.9, 11.5 -1.17
DBA/2J m 23.0 8.53   10 2.7 0.371 14.2, 35.5 0.21
MRL/MpJ m 24.8 13.1   10 4.15 0.529 8.8, 48.3 0.38
NZB/BlNJ m 5.91 0.884   10 0.279 0.15 4.6, 7.4 -1.37
NZW/LacJ m 23.0 10.2   10 3.23 0.444 14.2, 46.9 0.21
SPRET/EiJ m 4.79 1.11   9 0.369 0.231 3.4, 6.4 -1.48


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129X1/SvJ m 32.39 3.8714 40.0426 24.7374
A/HeJ m 5.51 3.8714 13.1626 0.0
A/J m 25.74 3.8714 33.3926 18.0874
AKR/J m 27.92 3.8714 35.5726 20.2674
B10.D2-Hc0 m 41.18 3.8714 48.8326 33.5274
BALB/cByJ m 22.9778 4.0808 31.0443 14.9112
BALB/cJ m 29.06 3.8714 36.7126 21.4074
C3H/HeJ m 21.15 3.8714 28.8026 13.4974
C57BL/6J m 15.12 2.7375 20.5312 9.7088
CAST/EiJ m 8.14 3.8714 15.7926 0.4874
DBA/2J m 22.97 3.8714 30.6226 15.3174
MRL/MpJ m 24.81 3.8714 32.4626 17.1574
NZB/BlNJ m 5.91 3.8714 13.5626 0.0
NZW/LacJ m 23.01 3.8714 30.6626 15.3574
SPRET/EiJ m 4.7889 4.0808 12.8554 0.0




  GWAS USING LINEAR MIXED MODELS