Project measure / variable:   Gavras1   BP_salt

ID, description, units MPD:14402   BP_salt   systolic blood pressure   [mmHg]  NaCl  
sodium chloride study
Data set, strains Gavras1   inbred   6 strains     sex: both     age: 9-12wks
Procedure tail cuff
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  STRAIN COMPARISON PLOT
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Gavras1 - systolic blood pressure NaCl



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested5 strains5 strains
Mean of the strain means112   mmHg 108   mmHg
Median of the strain means108   mmHg 106   mmHg
SD of the strain means± 9.97 ± 5.18
Coefficient of variation (CV)0.0891 0.0478
Min–max range of strain means103   –   128   mmHg 104   –   114   mmHg
Mean sample size per strain5.6   mice 6.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 65.1501 65.1501 1.0137 0.3196
strain 3 726.4861 242.162 3.768 0.0173
sex:strain 3 13.5872 4.5291 0.0705 0.9754
Residuals 43 2763.5064 64.2676


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
AKR/J f 106.0 5.82   8 2.06 0.0549 101.0, 118.0 -0.6
AKR/J m 104.0 7.21   8 2.55 0.069 93.4, 113.0 -0.85
C3H/HeJ f 103.0 10.7   5 4.79 0.104 88.5, 115.0 -0.9
C3H/HeJ m 104.0 7.87   6 3.21 0.0759 93.4, 116.0 -0.85
NOD/ShiLtJ m 114.0 5.87   8 2.08 0.0514 109.0, 128.0 1.08
PL/J f 115.0 5.25   7 1.98 0.0458 106.0, 120.0 0.3
PL/J m 114.0 8.62   3 4.98 0.0754 105.0, 122.0 1.08
RIIIS/J f 108.0 6.32   6 2.58 0.0585 99.9, 119.0 -0.4
RIIIS/J m 106.0 11.2   8 3.97 0.106 92.1, 124.0 -0.46
SWR/J f 128.0 8.49   2   6.0 0.0663 122.0, 134.0 1.6


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
AKR/J f 105.875 2.8343 111.591 100.159
AKR/J m 104.3875 2.8343 110.1035 98.6715
C3H/HeJ f 102.94 3.5852 110.1702 95.7098
C3H/HeJ m 103.6833 3.2728 110.2836 97.0831
PL/J f 114.7143 3.03 120.8249 108.6036
PL/J m 114.3333 4.6284 123.6675 104.9992
RIIIS/J f 107.9833 3.2728 114.5836 101.3831
RIIIS/J m 105.9625 2.8343 111.6785 100.2465


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
AKR/J both 105.1312 2.0042 109.1731 101.0894
C3H/HeJ both 103.3117 2.4272 108.2065 98.4168
PL/J both 114.5238 2.766 120.102 108.9456
RIIIS/J both 106.9729 2.1648 111.3386 102.6073




  GWAS USING LINEAR MIXED MODELS